Found 11 hits with Last Name = 'hernandez' and Initial = 'rj' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM86149
(CAS_131413 | NCS-382 | NSC_131413)Show InChI InChI=1S/C13H14O3/c14-12(15)8-10-6-3-5-9-4-1-2-7-11(9)13(10)16/h1-2,4,7-8,13,16H,3,5-6H2,(H,14,15)/p-1/b10-8- | UniProtKB/TrEMBL
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PC cid PC sid UniChem
Similars
| Article PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 675-9 (2003)
Article DOI: 10.1124/jpet.102.046797 BindingDB Entry DOI: 10.7270/Q2S1812F |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM86150
(UMB58)Show InChI InChI=1S/C5H10O3/c6-4-2-1-3-5(7)8/h6H,1-4H2,(H,7,8)/p-1 | UniProtKB/TrEMBL
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MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 675-9 (2003)
Article DOI: 10.1124/jpet.102.046797 BindingDB Entry DOI: 10.7270/Q2S1812F |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM86151
(UMB68)Show InChI InChI=1S/C6H12O3/c1-6(2,9)4-3-5(7)8/h9H,3-4H2,1-2H3,(H,7,8)/p-1 | UniProtKB/TrEMBL
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PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 675-9 (2003)
Article DOI: 10.1124/jpet.102.046797 BindingDB Entry DOI: 10.7270/Q2S1812F |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM86152
(UMB75)Show InChI InChI=1S/C7H14O3/c1-7(2,10)5-3-4-6(8)9/h10H,3-5H2,1-2H3,(H,8,9)/p-1 | UniProtKB/TrEMBL
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PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 305: 675-9 (2003)
Article DOI: 10.1124/jpet.102.046797 BindingDB Entry DOI: 10.7270/Q2S1812F |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50168281
(CHEMBL189853 | [3-(3-Phenyl-propoxy)-phenyl]-aceti...)Show InChI InChI=1S/C17H18O3/c18-17(19)13-15-8-4-10-16(12-15)20-11-5-9-14-6-2-1-3-7-14/h1-4,6-8,10,12H,5,9,11,13H2,(H,18,19) | UniProtKB/TrEMBL
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50168285
((3-Phenethyloxy-phenyl)-acetic acid | CHEMBL190961)Show InChI InChI=1S/C16H16O3/c17-16(18)12-14-7-4-8-15(11-14)19-10-9-13-5-2-1-3-6-13/h1-8,11H,9-10,12H2,(H,17,18) | UniProtKB/TrEMBL
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50168283
((3-hydroxyphenyl)acetic acid | (m-hydroxyphenyl)ac...)Show InChI InChI=1S/C8H8O3/c9-7-3-1-2-6(4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11) | UniProtKB/TrEMBL
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Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50060976
((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066)Show InChI InChI=1S/C14H12O3/c15-14(16)10-11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9H,10H2,(H,15,16) | UniProtKB/TrEMBL
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50023575
(4-hydroxy-butyric acid | 4-hydroxybutanoic acid | ...)Show InChI InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7) | UniProtKB/TrEMBL
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50168282
((3-Benzyloxy-phenyl)-acetic acid | CHEMBL190962)Show InChI InChI=1S/C15H14O3/c16-15(17)10-13-7-4-8-14(9-13)18-11-12-5-2-1-3-6-12/h1-9H,10-11H2,(H,16,17) | UniProtKB/TrEMBL
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CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |
Gamma-hydroxybutyrate receptor
(RAT) | BDBM50168284
(4-Phenoxy-butyric acid | CHEMBL190723)Show InChI InChI=1S/C10H12O3/c11-10(12)7-4-8-13-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12) | UniProtKB/TrEMBL
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CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 2.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description Displacement of [3H]-NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranes |
Bioorg Med Chem Lett 15: 3201-2 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.011 BindingDB Entry DOI: 10.7270/Q2MP52TK |
More data for this Ligand-Target Pair | |