Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3148 (2-pyridinone deriv. 54 | 5-ethyl-3-{[(2-methoxy-5,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3142 (2-pyridinone deriv. 48 | 5-ethyl-3-{[(2-methoxy-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3145 (2-pyridinone deriv. 51 | 5-ethyl-3-{[(5-ethyl-2-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3141 (2-pyridinone deriv. 47 | 5-ethyl-3-{[(2-methoxy-4-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3146 (2-pyridinone deriv. 52 | 5-ethyl-3-{[(5-ethyl-2-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3147 (2-pyridinone deriv. 53 | 5-ethyl-3-{[(6-methoxy-2,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3121 (2-pyridinone deriv. 27 | 5-ethyl-3-{[(2-methoxyphe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 265 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3123 (2-pyridinone deriv. 29 | 3-{[(2-ethoxyphenyl)methy...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3144 (2-pyridinone deriv. 50 | 5-ethyl-3-{[(4-ethyl-2-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3124 (2-pyridinone deriv. 30 | 5-ethyl-6-methyl-3-{[(2-n...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3119 (2-pyridinone deriv. 25 | 5-ethyl-3-{[(2-methoxypyr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3125 (2-pyridinone deriv. 31 | 2-{[(5-ethyl-6-methyl-2-o...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3135 (2-pyridinone deriv. 41 | 5-ethyl-3-{[(3-methoxyphe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3143 (2-pyridinone deriv. 49 | 5-ethyl-3-{[(2-methoxy-6-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3126 (2-pyridinone deriv. 32 | 5-ethyl-3-{[(2-fluorophen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3127 (2-pyridinone deriv. 33 | 3-{[(2-chlorophenyl)methy...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3128 (2-pyridinone deriv. 34 | 5-ethyl-6-methyl-3-({[2-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3139 (2-pyridinone deriv. 45 | 5-ethyl-3-{[(3-methoxypyr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3129 (2-pyridinone deriv. 35 | 5-ethyl-6-methyl-3-{[(2-m...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3140 (2-pyridinone deriv. 46 | 5-ethyl-3-{[(2-methoxy-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3130 (2-pyridinone deriv. 36 | 5-ethyl-3-{[(2-hydroxyphe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1298 (2-pyridinone deriv. 28 | 3-(benzylamino)-5-ethyl-6...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3131 (2-pyridinone deriv. 37 | 5-ethyl-3-{[(2-ethylpheny...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3136 (2-pyridinone deriv. 42 | 5-ethyl-3-{[(4-methoxyphe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3138 (2-pyridinone deriv. 44 | 5-ethyl-3-{[(4-methoxypyr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3132 (2-pyridinone deriv. 38 | 5-ethyl-6-methyl-3-({[2-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3133 (2-pyridinone deriv. 39 | 3-{[(2-aminophenyl)methyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3134 (2-pyridinone deriv. 40 | 5-ethyl-3-({[2-(methoxyme...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.55E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM3137 (2-pyridinone deriv. 43 | 5-ethyl-3-{[(3-methoxypyr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1308 (2-pyridinone deriv. 26 | 3-Aminopyridin-2(1H)-one ...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 249-55 (1993) Article DOI: 10.1021/jm00054a009 BindingDB Entry DOI: 10.7270/Q20863HM | |||||||||||
More data for this Ligand-Target Pair |