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Compile Data Set for Download or QSAR

Found 170 hits with Last Name = 'cseh' and Initial = 's'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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US Patent
n/an/a 0.100n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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US Patent
n/an/a 0.200n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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US Patent
n/an/a 0.5n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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US Patent
n/an/a 1n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 4


(Homo sapiens)
BDBM50058655
PNG
(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Show SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC
Show InChI InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
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n/an/a 59n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50232678
PNG
(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Show InChI InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2
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n/an/a 73n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50058655
PNG
(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Show SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC
Show InChI InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
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n/an/a 93n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM43362
PNG
(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Show SMILES CN(C)C(=S)SSC(=S)N(C)C
Show InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
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n/an/a 110n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50058655
PNG
(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Show SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC
Show InChI InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
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n/an/a 150n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM43362
PNG
(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Show SMILES CN(C)C(=S)SSC(=S)N(C)C
Show InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
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n/an/a 170n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50232678
PNG
(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Show InChI InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2
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n/an/a 170n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 4


(Homo sapiens)
BDBM43362
PNG
(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Show SMILES CN(C)C(=S)SSC(=S)N(C)C
Show InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
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n/an/a 180n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
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US Patent
n/an/a 280n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Protein-lysine 6-oxidase


(Homo sapiens (Human))
BDBM50058655
PNG
(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Show SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC
Show InChI InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
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n/an/a 320n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50463620
PNG
(CHEMBL4240937)
Show SMILES CCN1\C(C=Cc2ccccc12)=C1/C(=O)N(N=C1Nc1ccccc1)c1ccccc1 |c:4,18|
Show InChI InChI=1S/C26H22N4O/c1-2-29-22-16-10-9-11-19(22)17-18-23(29)24-25(27-20-12-5-3-6-13-20)28-30(26(24)31)21-14-7-4-8-15-21/h3-18H,2H2,1H3,(H,27,28)/b24-23-
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n/an/a 1.00E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Protein-lysine 6-oxidase


(Homo sapiens (Human))
BDBM43362
PNG
(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Show SMILES CN(C)C(=S)SSC(=S)N(C)C
Show InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
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n/an/a 1.04E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
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n/an/a 1.24E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50463622
PNG
(CHEMBL4245637)
Show SMILES CC1C(C)=NN(C1=O)c1ccccc1 |c:3|
Show InChI InChI=1S/C11H12N2O/c1-8-9(2)12-13(11(8)14)10-6-4-3-5-7-10/h3-8H,1-2H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256131
PNG
(US9487462, 13)
Show SMILES OC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-20-10-12-26-13-11-20)14-19-6-8-22(9-7-19)31-17-21-4-2-1-3-5-21/h1-13,18H,14-17H2,(H,29,30)
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US Patent
n/an/a 1.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256128
PNG
(US9487462, 10)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3cccnc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-19-3-1-9-25-11-19)13-18-5-7-21(8-6-18)31-16-20-4-2-10-26-12-20/h1-12,17H,13-16H2,(H,29,30)
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n/an/a 1.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Protein-lysine 6-oxidase


(Homo sapiens (Human))
BDBM50463618
PNG
(CHEMBL4241062)
Show SMILES CC1=NN(C(=O)\C1=C\NNc1nnc(C)c(O)n1)c1ccccc1 |t:1|
Show InChI InChI=1S/C15H15N7O2/c1-9-12(8-16-19-15-17-13(23)10(2)18-20-15)14(24)22(21-9)11-6-4-3-5-7-11/h3-8,16H,1-2H3,(H2,17,19,20,23)/b12-8+
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n/an/a 1.60E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
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n/an/a 1.76E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256125
PNG
(US9487462, 6)
Show SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C33H30N2O3S/c36-33(37)31-24-39-32(34-31)22-35(21-30(27-12-6-2-7-13-27)28-14-8-3-9-15-28)20-25-16-18-29(19-17-25)38-23-26-10-4-1-5-11-26/h1-19,24,30H,20-23H2,(H,36,37)
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n/an/a 1.76E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50463620
PNG
(CHEMBL4240937)
Show SMILES CCN1\C(C=Cc2ccccc12)=C1/C(=O)N(N=C1Nc1ccccc1)c1ccccc1 |c:4,18|
Show InChI InChI=1S/C26H22N4O/c1-2-29-22-16-10-9-11-19(22)17-18-23(29)24-25(27-20-12-5-3-6-13-20)28-30(26(24)31)21-14-7-4-8-15-21/h3-18H,2H2,1H3,(H,27,28)/b24-23-
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n/an/a 2.10E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 4


(Homo sapiens)
BDBM50463622
PNG
(CHEMBL4245637)
Show SMILES CC1C(C)=NN(C1=O)c1ccccc1 |c:3|
Show InChI InChI=1S/C11H12N2O/c1-8-9(2)12-13(11(8)14)10-6-4-3-5-7-10/h3-8H,1-2H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50463622
PNG
(CHEMBL4245637)
Show SMILES CC1C(C)=NN(C1=O)c1ccccc1 |c:3|
Show InChI InChI=1S/C11H12N2O/c1-8-9(2)12-13(11(8)14)10-6-4-3-5-7-10/h3-8H,1-2H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
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n/an/a 2.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Protein-lysine 6-oxidase


(Homo sapiens (Human))
BDBM50463622
PNG
(CHEMBL4245637)
Show SMILES CC1C(C)=NN(C1=O)c1ccccc1 |c:3|
Show InChI InChI=1S/C11H12N2O/c1-8-9(2)12-13(11(8)14)10-6-4-3-5-7-10/h3-8H,1-2H3
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n/an/a 2.60E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256133
PNG
(US9487462, 15)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H21FN2O2S/c26-22-12-8-19(9-13-22)15-28(16-24-27-23(17-31-24)25(29)30)14-18-6-10-21(11-7-18)20-4-2-1-3-5-20/h1-13,17H,14-16H2,(H,29,30)
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n/an/a 3.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256126
PNG
(US9487462, 7)
Show SMILES OC(=O)c1csc(CN(Cc2ccccc2)Cc2ccccc2)n1
Show InChI InChI=1S/C19H18N2O2S/c22-19(23)17-14-24-18(20-17)13-21(11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,14H,11-13H2,(H,22,23)
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n/an/a 3.20E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 4


(Homo sapiens)
BDBM50463615
PNG
(CHEMBL4251179)
Show SMILES CCOC(=O)c1sc(N\N=C2\C(N)=NN(C2=O)c2ccccc2)c(C(=O)OCC)c1C |c:12|
Show InChI InChI=1S/C20H21N5O5S/c1-4-29-19(27)13-11(3)15(20(28)30-5-2)31-17(13)23-22-14-16(21)24-25(18(14)26)12-9-7-6-8-10-12/h6-10,23H,4-5H2,1-3H3,(H2,21,24)/b22-14-
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n/an/a 3.30E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
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n/an/a 3.30E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256121
PNG
(US9487462, 2)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C27H26FN3O3S/c1-2-33-27(32)25-19-35-26(30-25)17-31(15-20-5-9-23(28)10-6-20)16-21-7-11-24(12-8-21)34-18-22-4-3-13-29-14-22/h3-14,19H,2,15-18H2,1H3
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n/an/a 3.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50463617
PNG
(CHEMBL4238380)
Show SMILES Cc1cc(c(C)o1)-c1ccc2c(n1)[nH]n(-c1ccccc1)c2=O
Show InChI InChI=1S/C18H15N3O2/c1-11-10-15(12(2)23-11)16-9-8-14-17(19-16)20-21(18(14)22)13-6-4-3-5-7-13/h3-10H,1-2H3,(H,19,20)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
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n/an/a 3.90E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
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n/an/a 4.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50463614
PNG
(CHEMBL4237334)
Show SMILES O=c1n([nH]c2nc(ccc12)-c1cccs1)-c1ccccc1
Show InChI InChI=1S/C16H11N3OS/c20-16-12-8-9-13(14-7-4-10-21-14)17-15(12)18-19(16)11-5-2-1-3-6-11/h1-10H,(H,17,18)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 3


(Homo sapiens (Human))
BDBM50463617
PNG
(CHEMBL4238380)
Show SMILES Cc1cc(c(C)o1)-c1ccc2c(n1)[nH]n(-c1ccccc1)c2=O
Show InChI InChI=1S/C18H15N3O2/c1-11-10-15(12(2)23-11)16-9-8-14-17(19-16)20-21(18(14)22)13-6-4-3-5-7-13/h3-10H,1-2H3,(H,19,20)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Protein-lysine 6-oxidase


(Homo sapiens (Human))
BDBM50463615
PNG
(CHEMBL4251179)
Show SMILES CCOC(=O)c1sc(N\N=C2\C(N)=NN(C2=O)c2ccccc2)c(C(=O)OCC)c1C |c:12|
Show InChI InChI=1S/C20H21N5O5S/c1-4-29-19(27)13-11(3)15(20(28)30-5-2)31-17(13)23-22-14-16(21)24-25(18(14)26)12-9-7-6-8-10-12/h6-10,23H,4-5H2,1-3H3,(H2,21,24)/b22-14-
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Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256134
PNG
(US9487462, 16)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-23-9-6-14-28-15-23)16-21-10-12-24(13-11-21)33-19-22-7-4-3-5-8-22/h3-15,20H,2,16-19H2,1H3
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n/an/a 5.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256120
PNG
(US9487462, 1)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3cccnc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-7-3-18(4-8-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-5-9-22(10-6-19)32-16-20-2-1-11-27-12-20/h1-12,17H,13-16H2,(H,30,31)
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n/an/a 5.70E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM256124
PNG
(US9487462, 5)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccc(F)c2)n1
Show InChI InChI=1S/C26H23FN2O3S/c27-22-8-4-7-21(13-22)15-29(16-25-28-24(18-33-25)26(30)31)14-19-9-11-23(12-10-19)32-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,30,31)
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n/an/a 6.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256141
PNG
(US9487462, 30)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C26H24FN3O3/c27-22-10-6-19(7-11-22)15-30(17-25-28-14-24(29-25)26(31)32)16-20-8-12-23(13-9-20)33-18-21-4-2-1-3-5-21/h1-14H,15-18H2,(H,28,29)(H,31,32)
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n/an/a 6.60E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256138
PNG
(US9487462, 20)
Show SMILES CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C27H27N3O3S/c1-2-32-27(31)25-20-34-26(29-25)18-30(17-22-12-14-28-15-13-22)16-21-8-10-24(11-9-21)33-19-23-6-4-3-5-7-23/h3-15,20H,2,16-19H2,1H3
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n/an/a 7.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Lysyl oxidase homolog 2


(Homo sapiens (Human))
BDBM50463614
PNG
(CHEMBL4237334)
Show SMILES O=c1n([nH]c2nc(ccc12)-c1cccs1)-c1ccccc1
Show InChI InChI=1S/C16H11N3OS/c20-16-12-8-9-13(14-7-4-10-21-14)17-15(12)18-19(16)11-5-2-1-3-6-11/h1-10H,(H,17,18)
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Article
PubMed
n/an/a 7.80E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...


Bioorg Med Chem Lett 28: 3113-3118 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.001
BindingDB Entry DOI: 10.7270/Q28P6366
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256139
PNG
(US9487462, 22)
Show SMILES OC(=O)c1c[nH]c(CN(Cc2ccc(F)cc2)Cc2ccc(OC(c3ccccc3)c3ccccc3)cc2)n1
Show InChI InChI=1S/C32H28FN3O3/c33-27-15-11-23(12-16-27)20-36(22-30-34-19-29(35-30)32(37)38)21-24-13-17-28(18-14-24)39-31(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-19,31H,20-22H2,(H,34,35)(H,37,38)
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n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
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n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256132
PNG
(US9487462, 14)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccccc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C25H23N3O3S/c29-25(30)23-18-32-24(27-23)16-28(15-21-7-4-12-26-13-21)14-19-8-10-22(11-9-19)31-17-20-5-2-1-3-6-20/h1-13,18H,14-17H2,(H,29,30)
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n/an/a 8.00E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM256130
PNG
(US9487462, 12)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1
Show InChI InChI=1S/C24H22N4O3S/c29-24(30)22-17-32-23(27-22)15-28(14-20-2-1-9-26-12-20)13-18-3-5-21(6-4-18)31-16-19-7-10-25-11-8-19/h1-12,17H,13-16H2,(H,29,30)
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n/an/a 8.50E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM256127
PNG
(US9487462, 9)
Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2ccc(OCc3ccncc3)cc2)n1
Show InChI InChI=1S/C25H22FN3O3S/c26-21-5-1-18(2-6-21)13-29(15-24-28-23(17-33-24)25(30)31)14-19-3-7-22(8-4-19)32-16-20-9-11-27-12-10-20/h1-12,17H,13-16H2,(H,30,31)
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n/an/a 8.80E+3n/an/an/an/a7.537



PharmaHungary 2000 Kft.; TargetEx Kft.

US Patent


Assay Description
Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...


US Patent US9487462 (2016)


BindingDB Entry DOI: 10.7270/Q2W094VZ
More data for this
Ligand-Target Pair
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