Found 204 hits with Last Name = 'zozulya' and Initial = 's' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM220447
(US10633379, Compound X | US9296741, 36)Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of BRD4 (unknown origin) |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273481
(CHEMBL4125931)Show SMILES Cc1noc2C(CC(N)=O)N=C(c3ccc(Cl)cc3)c3ccccc3-c12 |t:10| Show InChI InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of BRD4 (unknown origin) |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50117930
((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)Show SMILES Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1 Show InChI InChI=1S/C21H27N3O3S/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27/h3-9,18,23H,10-15H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Saint Petersburg State University
Curated by ChEMBL
| Assay Description Inhibition of human ERG expressed in cell membranes after 4 hrs by fluorescence polarization assay |
Bioorg Med Chem 24: 2954-2963 (2016)
Article DOI: 10.1016/j.bmc.2016.04.065 BindingDB Entry DOI: 10.7270/Q2SB47PK |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273482
(CHEMBL4127310)Show SMILES Cc1sc-2c(c1C)C(=NC(CC(=O)Nc1ccc(O)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1 |c:8| Show InChI InChI=1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of BRD4 (unknown origin) |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50399434
(CHEMBL2179387)Show InChI InChI=1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of BRD4 (unknown origin) |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049923
(CHEMBL3322421)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)c(Cl)c1 |c:14| Show InChI InChI=1S/C15H13Cl2N3O2S/c16-13-6-1-10(9-14(13)17)15-19-7-8-20(15)11-2-4-12(5-3-11)23(18,21)22/h1-6,9H,7-8H2,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50365463
(CHEMBL1232461)Show SMILES CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc12 |r,t:7| Show InChI InChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of BRD4 (unknown origin) |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049924
(CHEMBL3322422)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)c(c1)C(F)(F)F |c:14| Show InChI InChI=1S/C16H13ClF3N3O2S/c17-14-6-1-10(9-13(14)16(18,19)20)15-22-7-8-23(15)11-2-4-12(5-3-11)26(21,24)25/h1-6,9H,7-8H2,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273496
(CHEMBL4125924)Show InChI InChI=1S/C17H17N3O2S/c1-19-12-7-6-11(9-13(12)20(2)17(19)22)18-16(21)15-8-10-4-3-5-14(10)23-15/h6-9H,3-5H2,1-2H3,(H,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049888
(CHEMBL3322406)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)c(Cl)c1 |c:14| Show InChI InChI=1S/C16H14Cl2N2O2S/c1-23(21,22)13-5-3-12(4-6-13)20-9-8-19-16(20)11-2-7-14(17)15(18)10-11/h2-7,10H,8-9H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50032921
(CHEMBL1444120)Show SMILES Cc1ccc(c(C)c1)S(=O)(=O)Nc1ccc2n(C)c(=O)n(C)c2c1 Show InChI InChI=1S/C17H19N3O3S/c1-11-5-8-16(12(2)9-11)24(22,23)18-13-6-7-14-15(10-13)20(4)17(21)19(14)3/h5-10,18H,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049917
(CHEMBL3322415)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Cl)c1 |c:14| Show InChI InChI=1S/C15H14ClN3O2S/c16-12-3-1-2-11(10-12)15-18-8-9-19(15)13-4-6-14(7-5-13)22(17,20)21/h1-7,10H,8-9H2,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049894
(CHEMBL3322412)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Br)c1 |c:14| Show InChI InChI=1S/C15H14BrN3O2S/c16-12-3-1-2-11(10-12)15-18-8-9-19(15)13-4-6-14(7-5-13)22(17,20)21/h1-7,10H,8-9H2,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273497
(CHEMBL4129632)Show InChI InChI=1S/C18H16N2O4/c1-20-11-14(7-8-16(20)21)19-18(22)17-13(9-10-23-17)12-24-15-5-3-2-4-6-15/h2-11H,12H2,1H3,(H,19,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049892
(CHEMBL3322410)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)cc1 |c:14| Show InChI InChI=1S/C15H14ClN3O2S/c16-12-3-1-11(2-4-12)15-18-9-10-19(15)13-5-7-14(8-6-13)22(17,20)21/h1-8H,9-10H2,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049889
(CHEMBL3322407)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)c(c1)C(F)(F)F |c:14| Show InChI InChI=1S/C17H14ClF3N2O2S/c1-26(24,25)13-5-3-12(4-6-13)23-9-8-22-16(23)11-2-7-15(18)14(10-11)17(19,20)21/h2-7,10H,8-9H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049921
(CHEMBL3322419)Show SMILES COc1ccc(cc1Cl)C1=NCCN1c1ccc(cc1)S(N)(=O)=O |t:10| Show InChI InChI=1S/C16H16ClN3O3S/c1-23-15-7-2-11(10-14(15)17)16-19-8-9-20(16)12-3-5-13(6-4-12)24(18,21)22/h2-7,10H,8-9H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049922
(CHEMBL3322420)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(F)c(F)c1 |c:14| Show InChI InChI=1S/C15H13F2N3O2S/c16-13-6-1-10(9-14(13)17)15-19-7-8-20(15)11-2-4-12(5-3-11)23(18,21)22/h1-6,9H,7-8H2,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049879
(CHEMBL3322397)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Br)c1 |c:14| Show InChI InChI=1S/C16H15BrN2O2S/c1-22(20,21)15-7-5-14(6-8-15)19-10-9-18-16(19)12-3-2-4-13(17)11-12/h2-8,11H,9-10H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049890
(CHEMBL3322408)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(F)cc1 |c:14| Show InChI InChI=1S/C15H14FN3O2S/c16-12-3-1-11(2-4-12)15-18-9-10-19(15)13-5-7-14(8-6-13)22(17,20)21/h1-8H,9-10H2,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049878
(CHEMBL3322396)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(Cl)cc1 |c:14| Show InChI InChI=1S/C16H15ClN2O2S/c1-22(20,21)15-8-6-14(7-9-15)19-11-10-18-16(19)12-2-4-13(17)5-3-12/h2-9H,10-11H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049916
(CHEMBL3322414)Show SMILES NS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(F)c1 |c:14| Show InChI InChI=1S/C15H14FN3O2S/c16-12-3-1-2-11(10-12)15-18-8-9-19(15)13-4-6-14(7-5-13)22(17,20)21/h1-7,10H,8-9H2,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273483
(CHEMBL4129169)Show SMILES Cc1nc(cs1)-c1cccc(NC(=O)c2ccc3[nH]c(C)c(C)c3c2)c1 Show InChI InChI=1S/C21H19N3OS/c1-12-13(2)22-19-8-7-16(10-18(12)19)21(25)24-17-6-4-5-15(9-17)20-11-26-14(3)23-20/h4-11,22H,1-3H3,(H,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049882
(CHEMBL3322400)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(Cl)c1 |c:14| Show InChI InChI=1S/C16H15ClN2O2S/c1-22(20,21)15-7-5-14(6-8-15)19-10-9-18-16(19)12-3-2-4-13(17)11-12/h2-8,11H,9-10H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049919
(CHEMBL3322417)Show SMILES COc1ccc(cc1F)C1=NCCN1c1ccc(cc1)S(N)(=O)=O |t:10| Show InChI InChI=1S/C16H16FN3O3S/c1-23-15-7-2-11(10-14(15)17)16-19-8-9-20(16)12-3-5-13(6-4-12)24(18,21)22/h2-7,10H,8-9H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049920
(CHEMBL3322418)Show SMILES COc1cc(ccc1F)C1=NCCN1c1ccc(cc1)S(N)(=O)=O |t:10| Show InChI InChI=1S/C16H16FN3O3S/c1-23-15-10-11(2-7-14(15)17)16-19-8-9-20(16)12-3-5-13(6-4-12)24(18,21)22/h2-7,10H,8-9H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049918
(CHEMBL3322416)Show SMILES Cc1cccc(c1)C1=NCCN1c1ccc(cc1)S(N)(=O)=O |t:8| Show InChI InChI=1S/C16H17N3O2S/c1-12-3-2-4-13(11-12)16-18-9-10-19(16)14-5-7-15(8-6-14)22(17,20)21/h2-8,11H,9-10H2,1H3,(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049895
(CHEMBL3322413)Show SMILES CC1CN(C(=N1)c1cccc(Br)c1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C16H16BrN3O2S/c1-11-10-20(14-5-7-15(8-6-14)23(18,21)22)16(19-11)12-3-2-4-13(17)9-12/h2-9,11H,10H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049893
(CHEMBL3322411)Show SMILES CC1CN(C(=N1)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C16H16ClN3O2S/c1-11-10-20(14-6-8-15(9-7-14)23(18,21)22)16(19-11)12-2-4-13(17)5-3-12/h2-9,11H,10H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049891
(CHEMBL3322409)Show SMILES CC1CN(C(=N1)c1ccc(F)cc1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C16H16FN3O2S/c1-11-10-20(14-6-8-15(9-7-14)23(18,21)22)16(19-11)12-2-4-13(17)5-3-12/h2-9,11H,10H2,1H3,(H2,18,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049887
(CHEMBL3322405)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(F)c(F)c1 |c:14| Show InChI InChI=1S/C16H14F2N2O2S/c1-23(21,22)13-5-3-12(4-6-13)20-9-8-19-16(20)11-2-7-14(17)15(18)10-11/h2-7,10H,8-9H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049886
(CHEMBL3322404)Show SMILES COc1ccc(cc1Cl)C1=NCCN1c1ccc(cc1)S(C)(=O)=O |t:10| Show InChI InChI=1S/C17H17ClN2O3S/c1-23-16-8-3-12(11-15(16)18)17-19-9-10-20(17)13-4-6-14(7-5-13)24(2,21)22/h3-8,11H,9-10H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049885
(CHEMBL3322403)Show SMILES COc1cc(ccc1F)C1=NCCN1c1ccc(cc1)S(C)(=O)=O |t:10| Show InChI InChI=1S/C17H17FN2O3S/c1-23-16-11-12(3-8-15(16)18)17-19-9-10-20(17)13-4-6-14(7-5-13)24(2,21)22/h3-8,11H,9-10H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049884
(CHEMBL3322402)Show SMILES COc1ccc(cc1F)C1=NCCN1c1ccc(cc1)S(C)(=O)=O |t:10| Show InChI InChI=1S/C17H17FN2O3S/c1-23-16-8-3-12(11-15(16)18)17-19-9-10-20(17)13-4-6-14(7-5-13)24(2,21)22/h3-8,11H,9-10H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049883
(CHEMBL3322401)Show SMILES Cc1cccc(c1)C1=NCCN1c1ccc(cc1)S(C)(=O)=O |t:8| Show InChI InChI=1S/C17H18N2O2S/c1-13-4-3-5-14(12-13)17-18-10-11-19(17)15-6-8-16(9-7-15)22(2,20)21/h3-9,12H,10-11H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049881
(CHEMBL3322399)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1cccc(F)c1 |c:14| Show InChI InChI=1S/C16H15FN2O2S/c1-22(20,21)15-7-5-14(6-8-15)19-10-9-18-16(19)12-3-2-4-13(17)11-12/h2-8,11H,9-10H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049880
(CHEMBL3322398)Show SMILES CC1CN(C(=N1)c1cccc(Br)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C17H17BrN2O2S/c1-12-11-20(15-6-8-16(9-7-15)23(2,21)22)17(19-12)13-4-3-5-14(18)10-13/h3-10,12H,11H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049877
(CHEMBL3322395)Show SMILES CC1CN(C(=N1)c1ccc(F)cc1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C17H17FN2O2S/c1-12-11-20(15-7-9-16(10-8-15)23(2,21)22)17(19-12)13-3-5-14(18)6-4-13/h3-10,12H,11H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049876
(CHEMBL3322394)Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCN=C1c1ccc(F)cc1 |c:14| Show InChI InChI=1S/C16H15FN2O2S/c1-22(20,21)15-8-6-14(7-9-15)19-11-10-18-16(19)12-2-4-13(17)5-3-12/h2-9H,10-11H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50049875
(CHEMBL3322393)Show SMILES CC1CN(C(=N1)c1ccc(Cl)cc1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C17H17ClN2O2S/c1-12-11-20(15-7-9-16(10-8-15)23(2,21)22)17(19-12)13-3-5-14(18)6-4-13/h3-10,12H,11H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50032911
(CHEMBL1535485)Show InChI InChI=1S/C17H17N3O3/c1-19-14-8-7-12(10-15(14)20(2)17(19)22)18-16(21)11-5-4-6-13(9-11)23-3/h4-10H,1-3H3,(H,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273480
(CHEMBL4126342)Show InChI InChI=1S/C19H23N3O3/c1-21-16-9-8-15(12-17(16)22(2)19(21)23)20-13-14-6-4-5-7-18(14)25-11-10-24-3/h4-9,12,20H,10-11,13H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50271103
(CHEMBL4129770)Show SMILES Cc1cc2cc(NC(=O)c3sc4nc(ccc4c3C)C(F)(F)F)ccc2[nH]1 Show InChI InChI=1S/C19H14F3N3OS/c1-9-7-11-8-12(3-5-14(11)23-9)24-17(26)16-10(2)13-4-6-15(19(20,21)22)25-18(13)27-16/h3-8,23H,1-2H3,(H,24,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273493
(CHEMBL4127163)Show SMILES Cc1cc2cc(NC(=O)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3)ccc2[nH]1 Show InChI InChI=1S/C22H16F3N3O2/c1-13-10-15-11-17(5-8-19(15)27-13)28-21(29)14-2-6-18(7-3-14)30-20-9-4-16(12-26-20)22(23,24)25/h2-12,27H,1H3,(H,28,29) | PDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273495
(CHEMBL4127306)Show SMILES COc1ccc(OC)c(CCC(=O)Nc2ccc3n(C)c(=O)n(C)c3c2)c1 Show InChI InChI=1S/C20H23N3O4/c1-22-16-8-6-14(12-17(16)23(2)20(22)25)21-19(24)10-5-13-11-15(26-3)7-9-18(13)27-4/h6-9,11-12H,5,10H2,1-4H3,(H,21,24) | PDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50270480
(CHEMBL4126540)Show SMILES CC1CCCC(C)N1C(=O)CSc1nc2sc3CCCCc3c2c(=O)n1C Show InChI InChI=1S/C20H27N3O2S2/c1-12-7-6-8-13(2)23(12)16(24)11-26-20-21-18-17(19(25)22(20)3)14-9-4-5-10-15(14)27-18/h12-13H,4-11H2,1-3H3 | PDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273479
(CHEMBL4128551)Show SMILES Cc1ccc(cc1[N+]([O-])=O)C(=O)Nc1ccc2nc(sc2c1)N1CCCC1 Show InChI InChI=1S/C19H18N4O3S/c1-12-4-5-13(10-16(12)23(25)26)18(24)20-14-6-7-15-17(11-14)27-19(21-15)22-8-2-3-9-22/h4-7,10-11H,2-3,8-9H2,1H3,(H,20,24) | PDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50057932
(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)Show SMILES Cc1cn(c(n1)-c1ccc(Cl)cc1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H15ClN2O2S/c1-12-11-20(15-7-9-16(10-8-15)23(2,21)22)17(19-12)13-3-5-14(18)6-4-13/h3-11H,1-2H3 | PDB
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B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 using fluorometric substrate by fluorescent inhibitor screening assay |
Eur J Med Chem 84: 160-72 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.023 BindingDB Entry DOI: 10.7270/Q2WQ05FT |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50273484
(CHEMBL4127934)Show InChI InChI=1S/C17H14ClNO3/c18-12-7-8-15-14(11-12)16(20)17(21)19(15)9-4-10-22-13-5-2-1-3-6-13/h1-3,5-8,11H,4,9-10H2 | PDB
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UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bienta/Enamine Ltd.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assay |
Bioorg Med Chem 26: 3399-3405 (2018)
Article DOI: 10.1016/j.bmc.2018.05.010 BindingDB Entry DOI: 10.7270/Q2H70J9B |
More data for this Ligand-Target Pair | |
Free fatty acid receptor 1
(Homo sapiens (Human)) | BDBM50107285
(CHEMBL3601060)Show InChI InChI=1S/C16H14N2O5/c19-15(20)8-5-11-3-6-12(7-4-11)22-10-14-17-16(18-23-14)13-2-1-9-21-13/h1-4,6-7,9H,5,8,10H2,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
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| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Enamine Ltd
Curated by ChEMBL
| Assay Description Agonist activity at GPR40 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin |
Bioorg Med Chem Lett 25: 3105-11 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.018 BindingDB Entry DOI: 10.7270/Q26D5VS5 |
More data for this Ligand-Target Pair | |