Compile Data Set for Download or QSAR

Found 16 hits with Last Name = 'levine' and Initial = 'sd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226906 (CHEMBL30001) Show SMILES COc1cc2nc(O)nc(Cc3ccccc3)c2cc1OC Show InChI InChI=1S/C17H16N2O3/c1-21-15-9-12-13(8-11-6-4-3-5-7-11)18-17(20)19-14(12)10-16(15)22-2/h3-7,9-10H,8H2,1-2H3,(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226909 (CHEMBL31133) Show SMILES COc1cc2nc(O)nc(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C16H14N2O3/c1-20-13-8-11-12(9-14(13)21-2)17-16(19)18-15(11)10-6-4-3-5-7-10/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226910 (Bemarinone) Show SMILES COc1ccc2[nH]c(=O)nc(C)c2c1OC Show InChI InChI=1S/C11H12N2O3/c1-6-9-7(13-11(14)12-6)4-5-8(15-2)10(9)16-3/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 0.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226908 (CHEMBL30387) Show SMILES CCc1nc(O)nc2ccc(OC)c(OC)c12 Show InChI InChI=1S/C12H14N2O3/c1-4-7-10-8(14-12(15)13-7)5-6-9(16-2)11(10)17-3/h5-6H,4H2,1-3H3,(H,13,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226905 (CHEMBL1743762) Show SMILES Br.Cc1nc(O)nc2ccc(O)c(O)c12 Show InChI InChI=1S/C9H8N2O3/c1-4-7-5(11-9(14)10-4)2-3-6(12)8(7)13/h2-3,12-13H,1H3,(H,10,11,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226907 (CHEMBL30636) Show SMILES COc1cc2nc(O)nc(C3CCCC3)c2cc1OC Show InChI InChI=1S/C15H18N2O3/c1-19-12-7-10-11(8-13(12)20-2)16-15(18)17-14(10)9-5-3-4-6-9/h7-9H,3-6H2,1-2H3,(H,16,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226913 (CHEMBL30542) Show SMILES COc1cc(OC)c2c(C)nc(O)nc2c1 Show InChI InChI=1S/C11H12N2O3/c1-6-10-8(13-11(14)12-6)4-7(15-2)5-9(10)16-3/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226912 (CHEMBL284443) Show SMILES CN(C)c1ccc2nc(O)nc(C)c2c1 Show InChI InChI=1S/C11H13N3O/c1-7-9-6-8(14(2)3)4-5-10(9)13-11(15)12-7/h4-6H,1-3H3,(H,12,13,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226914 (CHEMBL30607) Show SMILES COc1cc2nc(O)nc(C(C)C)c2cc1OC Show InChI InChI=1S/C13H16N2O3/c1-7(2)12-8-5-10(17-3)11(18-4)6-9(8)14-13(16)15-12/h5-7H,1-4H3,(H,14,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM34651 (Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226903 (CHEMBL30699) Show SMILES COc1cc2nc(O)nc(C)c2cc1OC Show InChI InChI=1S/C11H12N2O3/c1-6-7-4-9(15-2)10(16-3)5-8(7)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226915 (CHEMBL284798) Show SMILES COc1cc2nc(O)nc(c2cc1OC)C(F)(F)F Show InChI InChI=1S/C11H9F3N2O3/c1-18-7-3-5-6(4-8(7)19-2)15-10(17)16-9(5)11(12,13)14/h3-4H,1-2H3,(H,15,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226904 (CHEMBL30629) Show SMILES COc1ccc(OC)c2c(C)nc(O)nc12 Show InChI InChI=1S/C11H12N2O3/c1-6-9-7(15-2)4-5-8(16-3)10(9)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226916 (CHEMBL281242) Show SMILES Cc1nc(O)nc2ccccc12 Show InChI InChI=1S/C9H8N2O/c1-6-7-4-2-3-5-8(7)11-9(12)10-6/h2-5H,1H3,(H,10,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226911 (CHEMBL30541) Show SMILES COc1cc(OC)c2nc(O)nc(C)c2c1 Show InChI InChI=1S/C11H12N2O3/c1-6-8-4-7(15-2)5-9(16-3)10(8)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226902 (CHEMBL435758) Show SMILES CN1CCN(CC1)c1ccc2nc(O)nc(C)c2c1 Show InChI InChI=1S/C14H18N4O/c1-10-12-9-11(18-7-5-17(2)6-8-18)3-4-13(12)16-14(19)15-10/h3-4,9H,5-8H2,1-2H3,(H,15,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair