Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50232636![]() ((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50346601![]() (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50346601![]() (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50232636![]() ((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50232636![]() ((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50346601![]() (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50316020![]() ((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50346601![]() (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50232636![]() ((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50316020![]() ((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50232635![]() (CHEMBL4089985) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50316020![]() ((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50232635![]() (CHEMBL4089985) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50316020![]() ((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50232634![]() (CHEBI:67726 | Furospongin 1) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50232634![]() (CHEBI:67726 | Furospongin 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50232634![]() (CHEBI:67726 | Furospongin 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50092807![]() (CHEMBL3586411) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50234486![]() (Melophlin C) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Bioorg Med Chem Lett 27: 999-1002 (2017) Article DOI: 10.1016/j.bmcl.2016.12.077 BindingDB Entry DOI: 10.7270/Q2FT8P98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50092807![]() (CHEMBL3586411) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50092807![]() (CHEMBL3586411) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50092807![]() (CHEMBL3586411) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50256931![]() (CHEMBL1186032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50256931![]() (CHEMBL1186032) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase 3 (Homo sapiens (Human)) | BDBM50256931![]() (CHEMBL1186032) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50256931![]() (CHEMBL1186032) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Natural Product Chemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan. Electronic address: yamazaki@tohoku-mpu.ac. Curated by ChEMBL | Assay Description Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ... | Bioorg Med Chem Lett 27: 2207-2209 (2017) Article DOI: 10.1016/j.bmcl.2017.03.033 BindingDB Entry DOI: 10.7270/Q2XP77DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50232635![]() (CHEMBL4089985) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50232635![]() (CHEMBL4089985) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50232634![]() (CHEBI:67726 | Furospongin 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su... | Bioorg Med Chem Lett 27: 1159-1161 (2017) Article DOI: 10.1016/j.bmcl.2017.01.071 BindingDB Entry DOI: 10.7270/Q2ST7S23 | |||||||||||
More data for this Ligand-Target Pair |