Compile Data Set for Download or QSAR

Found 57 hits with Last Name = 'moon' and Initial = 'sk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304788 (CHEMBL594160 | methyl 4-(3-chloro-4-methoxybenzyla...) Show SMILES COC(=O)N(C)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O5/c1-27(22(29)32-4)17-10-15-19(14(7-8-28)20(17)31-3)25-12-26-21(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,7-8,11H2,1-4H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304790 (CHEMBL595330 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCN(C(=O)CC)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C24H29ClN4O4/c1-5-21(31)29(6-2)19-12-17-22(16(9-10-30)23(19)33-4)27-14-28-24(17)26-13-15-7-8-20(32-3)18(25)11-15/h7-8,11-12,14,30H,5-6,9-10,13H2,1-4H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304792 (CHEMBL595104 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(cc23)N(C)C(=O)C2CC2)cc1Cl Show InChI InChI=1S/C24H27ClN4O4/c1-29(24(31)15-5-6-15)19-11-17-21(16(8-9-30)22(19)33-3)27-13-28-23(17)26-12-14-4-7-20(32-2)18(25)10-14/h4,7,10-11,13,15,30H,5-6,8-9,12H2,1-3H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246252 (CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O4/c1-4-19(29)27-17-10-15-20(14(7-8-28)21(17)31-3)25-12-26-22(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,4,7-8,11H2,1-3H3,(H,27,29)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246252 (CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O4/c1-4-19(29)27-17-10-15-20(14(7-8-28)21(17)31-3)25-12-26-22(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,4,7-8,11H2,1-3H3,(H,27,29)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304789 (CHEMBL604271 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)N(C)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C23H27ClN4O4/c1-5-20(30)28(2)18-11-16-21(15(8-9-29)22(18)32-4)26-13-27-23(16)25-12-14-6-7-19(31-3)17(24)10-14/h6-7,10-11,13,29H,5,8-9,12H2,1-4H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304791 (CHEMBL592986 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(cc23)N(C)C(=O)C(C)C)cc1Cl Show InChI InChI=1S/C24H29ClN4O4/c1-14(2)24(31)29(3)19-11-17-21(16(8-9-30)22(19)33-5)27-13-28-23(17)26-12-15-6-7-20(32-4)18(25)10-15/h6-7,10-11,13-14,30H,8-9,12H2,1-5H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304786 (CHEMBL603422 | methyl 4-(3-chloro-4-methoxybenzyla...) Show SMILES COC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C21H23ClN4O5/c1-29-17-5-4-12(8-15(17)22)10-23-20-14-9-16(26-21(28)31-3)19(30-2)13(6-7-27)18(14)24-11-25-20/h4-5,8-9,11,27H,6-7,10H2,1-3H3,(H,26,28)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246104 (CHEMBL512174 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C(F)(F)F)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H22ClF3N4O3/c1-4-5-13-18-14(9-16(19(13)33-3)30-21(31)22(24,25)26)20(29-11-28-18)27-10-12-6-7-17(32-2)15(23)8-12/h6-9,11H,4-5,10H2,1-3H3,(H,30,31)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246145 (CHEMBL471702 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)CC)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C23H27ClN4O3/c1-5-7-15-21-16(11-18(22(15)31-4)28-20(29)6-2)23(27-13-26-21)25-12-14-8-9-19(30-3)17(24)10-14/h8-11,13H,5-7,12H2,1-4H3,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246015 (CHEMBL473301 | N-(3-chloro-4-methoxybenzyl)-7-chlo...) Show SMILES COc1ccc(CNc2ncnc3cc(Cl)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O3/c1-25-15-3-2-9(4-12(15)18)7-19-16-10-5-14(22(23)24)11(17)6-13(10)20-8-21-16/h2-6,8H,7H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246199 (CHEMBL488265 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(C)=O)cc23)cc1Cl Show InChI InChI=1S/C21H23ClN4O4/c1-12(28)26-17-9-15-19(14(6-7-27)20(17)30-3)24-11-25-21(15)23-10-13-4-5-18(29-2)16(22)8-13/h4-5,8-9,11,27H,6-7,10H2,1-3H3,(H,26,28)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304784 (CHEMBL596454 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NS(C)(=O)=O)cc23)cc1Cl Show InChI InChI=1S/C20H23ClN4O5S/c1-29-17-5-4-12(8-15(17)21)10-22-20-14-9-16(25-31(3,27)28)19(30-2)13(6-7-26)18(14)23-11-24-20/h4-5,8-9,11,25-26H,6-7,10H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246070 (CHEMBL470310 | N-(3-chloro-4-methoxybenzyl)-8-ally...) Show SMILES COc1ccc(CNc2ncnc3c(CC=C)c(OC)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C20H19ClN4O4/c1-4-5-13-18-14(9-16(25(26)27)19(13)29-3)20(24-11-23-18)22-10-12-6-7-17(28-2)15(21)8-12/h4,6-9,11H,1,5,10H2,2-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246069 (4-(3-chloro-4-methoxybenzylamino)-8-allyl-6-nitroq...) Show SMILES COc1ccc(CNc2ncnc3c(CC=C)c(O)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C19H17ClN4O4/c1-3-4-12-17-13(8-15(18(12)25)24(26)27)19(23-10-22-17)21-9-11-5-6-16(28-2)14(20)7-11/h3,5-8,10,25H,1,4,9H2,2H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304785 (2-(4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-6-[...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NS(=O)(=O)N(C)C)cc23)cc1Cl Show InChI InChI=1S/C21H26ClN5O5S/c1-27(2)33(29,30)26-17-10-15-19(14(7-8-28)20(17)32-4)24-12-25-21(15)23-11-13-5-6-18(31-3)16(22)9-13/h5-6,9-10,12,26,28H,7-8,11H2,1-4H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14777 ((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...) Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(C)C2=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM14777 ((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...) Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(C)C2=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246146 (CHEMBL471703 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C(C)(C)C)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C25H31ClN4O3/c1-7-8-16-21-17(12-19(22(16)33-6)30-24(31)25(2,3)4)23(29-14-28-21)27-13-15-9-10-20(32-5)18(26)11-15/h9-12,14H,7-8,13H2,1-6H3,(H,30,31)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246148 (CHEMBL470492 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCN(C)C)c(OC)c(NC(=O)C(F)(F)F)cc23)cc1Cl Show InChI InChI=1S/C23H25ClF3N5O3/c1-32(2)8-7-14-19-15(10-17(20(14)35-4)31-22(33)23(25,26)27)21(30-12-29-19)28-11-13-5-6-18(34-3)16(24)9-13/h5-6,9-10,12H,7-8,11H2,1-4H3,(H,31,33)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304787 (CHEMBL596489 | ethyl 4-(3-chloro-4-methoxybenzylam...) Show SMILES CCOC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O5/c1-4-32-22(29)27-17-10-15-19(14(7-8-28)20(17)31-3)25-12-26-21(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,4,7-8,11H2,1-3H3,(H,27,29)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246197 (CHEMBL520074 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CC=C)c1OC Show InChI InChI=1S/C23H25ClN4O3/c1-5-7-15-21-16(11-18(22(15)31-4)28-20(29)6-2)23(27-13-26-21)25-12-14-8-9-19(30-3)17(24)10-14/h5,8-11,13H,1,6-7,12H2,2-4H3,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246106 (CHEMBL471529 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(C)=O)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H25ClN4O3/c1-5-6-15-20-16(10-18(21(15)30-4)27-13(2)28)22(26-12-25-20)24-11-14-7-8-19(29-3)17(23)9-14/h7-10,12H,5-6,11H2,1-4H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246107 (CHEMBL471701 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C2CC2)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C24H27ClN4O3/c1-4-5-16-21-17(11-19(22(16)32-3)29-24(30)15-7-8-15)23(28-13-27-21)26-12-14-6-9-20(31-2)18(25)10-14/h6,9-11,13,15H,4-5,7-8,12H2,1-3H3,(H,29,30)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246147 (CHEMBL513593 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCN4CCCCC4)c(OC)c(NC(=O)C(F)(F)F)cc23)cc1Cl Show InChI InChI=1S/C26H29ClF3N5O3/c1-37-21-7-6-16(12-19(21)27)14-31-24-18-13-20(34-25(36)26(28,29)30)23(38-2)17(22(18)32-15-33-24)8-11-35-9-4-3-5-10-35/h6-7,12-13,15H,3-5,8-11,14H2,1-2H3,(H,34,36)(H,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246251 (CHEMBL488080 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(=O)C(C)C)cc23)cc1Cl Show InChI InChI=1S/C23H27ClN4O4/c1-13(2)23(30)28-18-10-16-20(15(7-8-29)21(18)32-4)26-12-27-22(16)25-11-14-5-6-19(31-3)17(24)9-14/h5-6,9-10,12-13,29H,7-8,11H2,1-4H3,(H,28,30)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246105 (CHEMBL471528 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)CN)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H26ClN5O3/c1-4-5-14-20-15(9-17(21(14)31-3)28-19(29)10-24)22(27-12-26-20)25-11-13-6-7-18(30-2)16(23)8-13/h6-9,12H,4-5,10-11,24H2,1-3H3,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246068 (CHEMBL472558 | N-(3-chloro-4-methoxybenzyl)-7-meth...) Show SMILES COc1ccc(CNc2ncnc3cc(OC)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C17H15ClN4O4/c1-25-15-4-3-10(5-12(15)18)8-19-17-11-6-14(22(23)24)16(26-2)7-13(11)20-9-21-17/h3-7,9H,8H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246198 (CHEMBL488091 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CC=C)c1OC Show InChI InChI=1S/C24H27ClN4O3/c1-5-7-16-22-17(12-19(23(16)32-4)29-21(30)8-6-2)24(28-14-27-22)26-13-15-9-10-20(31-3)18(25)11-15/h5,9-12,14H,1,6-8,13H2,2-4H3,(H,29,30)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246067 (CHEMBL524871 | N4-(3-chloro-4-methoxybenzyl)-N7,N7...) Show SMILES COc1ccc(CNc2ncnc3cc(N(C)C)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C18H18ClN5O3/c1-23(2)15-8-14-12(7-16(15)24(25)26)18(22-10-21-14)20-9-11-4-5-17(27-3)13(19)6-11/h4-8,10H,9H2,1-3H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304788 (CHEMBL594160 | methyl 4-(3-chloro-4-methoxybenzyla...) Show SMILES COC(=O)N(C)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O5/c1-27(22(29)32-4)17-10-15-19(14(7-8-28)20(17)31-3)25-12-26-21(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,7-8,11H2,1-4H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM14777 ((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...) Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(C)C2=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304789 (CHEMBL604271 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)N(C)c1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C23H27ClN4O4/c1-5-20(30)28(2)18-11-16-21(15(8-9-29)22(18)32-4)26-13-27-23(16)25-12-14-6-7-19(31-3)17(24)10-14/h6-7,10-11,13,29H,5,8-9,12H2,1-4H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304792 (CHEMBL595104 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(cc23)N(C)C(=O)C2CC2)cc1Cl Show InChI InChI=1S/C24H27ClN4O4/c1-29(24(31)15-5-6-15)19-11-17-21(16(8-9-30)22(19)33-3)27-13-28-23(17)26-12-14-4-7-20(32-2)18(25)10-14/h4,7,10-11,13,15,30H,5-6,8-9,12H2,1-3H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50246252 (CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O4/c1-4-19(29)27-17-10-15-20(14(7-8-28)21(17)31-3)25-12-26-22(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,4,7-8,11H2,1-3H3,(H,27,29)(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246016 (CHEMBL473507 | N4-(3-chloro-4-methoxybenzyl)-N7-(2...) Show SMILES COc1ccc(CNc2ncnc3cc(NCCN)c(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C18H19ClN6O3/c1-28-17-3-2-11(6-13(17)19)9-22-18-12-7-16(25(26)27)15(21-5-4-20)8-14(12)23-10-24-18/h2-3,6-8,10,21H,4-5,9,20H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304787 (CHEMBL596489 | ethyl 4-(3-chloro-4-methoxybenzylam...) Show SMILES CCOC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C22H25ClN4O5/c1-4-32-22(29)27-17-10-15-19(14(7-8-28)20(17)31-3)25-12-26-21(15)24-11-13-5-6-18(30-2)16(23)9-13/h5-6,9-10,12,28H,4,7-8,11H2,1-3H3,(H,27,29)(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304786 (CHEMBL603422 | methyl 4-(3-chloro-4-methoxybenzyla...) Show SMILES COC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC Show InChI InChI=1S/C21H23ClN4O5/c1-29-17-5-4-12(8-15(17)22)10-23-20-14-9-16(26-21(28)31-3)19(30-2)13(6-7-27)18(14)24-11-25-20/h4-5,8-9,11,27H,6-7,10H2,1-3H3,(H,26,28)(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246071 (CHEMBL470311 | N4-(3-chloro-4-methoxybenzyl)-8-all...) Show SMILES COc1ccc(CNc2ncnc3c(CC=C)c(OC)c(N)cc23)cc1Cl Show InChI InChI=1S/C20H21ClN4O2/c1-4-5-13-18-14(9-16(22)19(13)27-3)20(25-11-24-18)23-10-12-6-7-17(26-2)15(21)8-12/h4,6-9,11H,1,5,10,22H2,2-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM50304791 (CHEMBL592986 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(cc23)N(C)C(=O)C(C)C)cc1Cl Show InChI InChI=1S/C24H29ClN4O4/c1-14(2)24(31)29(3)19-11-17-21(16(8-9-30)22(19)33-5)27-13-28-23(17)26-12-15-6-7-20(32-4)18(25)10-15/h6-7,10-11,13-14,30H,8-9,12H2,1-5H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50246200 (CHEMBL487247 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(=O)c4ccccn4)cc23)cc1Cl Show InChI InChI=1S/C25H24ClN5O4/c1-34-21-7-6-15(11-18(21)26)13-28-24-17-12-20(31-25(33)19-5-3-4-9-27-19)23(35-2)16(8-10-32)22(17)29-14-30-24/h3-7,9,11-12,14,32H,8,10,13H2,1-2H3,(H,31,33)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bos taurus (Bovine))	BDBM14777 ((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...) Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(C)C2=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine retina PDE6				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50246104 (CHEMBL512174 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C(F)(F)F)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H22ClF3N4O3/c1-4-5-13-18-14(9-16(19(13)33-3)30-21(31)22(24,25)26)20(29-11-28-18)27-10-12-6-7-17(32-2)15(23)8-12/h6-9,11H,4-5,10H2,1-3H3,(H,30,31)(H,27,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50246251 (CHEMBL488080 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(=O)C(C)C)cc23)cc1Cl Show InChI InChI=1S/C23H27ClN4O4/c1-13(2)23(30)28-18-10-16-20(15(7-8-29)21(18)32-4)26-12-27-22(16)25-11-14-5-6-19(31-3)17(24)9-14/h5-6,9-10,12-13,29H,7-8,11H2,1-4H3,(H,28,30)(H,25,26,27)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50246145 (CHEMBL471702 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)CC)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C23H27ClN4O3/c1-5-7-15-21-16(11-18(22(15)31-4)28-20(29)6-2)23(27-13-26-21)25-12-14-8-9-19(30-3)17(24)10-14/h8-11,13H,5-7,12H2,1-4H3,(H,28,29)(H,25,26,27)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50246197 (CHEMBL520074 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CC=C)c1OC Show InChI InChI=1S/C23H25ClN4O3/c1-5-7-15-21-16(11-18(22(15)31-4)28-20(29)6-2)23(27-13-26-21)25-12-14-8-9-19(30-3)17(24)10-14/h5,8-11,13H,1,6-7,12H2,2-4H3,(H,28,29)(H,25,26,27)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair

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