Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50304784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50304784 (CHEMBL596454 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NS(C)(=O)=O)cc23)cc1Cl Show InChI InChI=1S/C20H23ClN4O5S/c1-29-17-5-4-12(8-15(17)21)10-22-20-14-9-16(25-31(3,27)28)19(30-2)13(6-7-26)18(14)23-11-24-20/h4-5,8-9,11,25-26H,6-7,10H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine platelet PDE5				Bioorg Med Chem Lett 20: 383-6 (2010) Article DOI: 10.1016/j.bmcl.2009.10.071 BindingDB Entry DOI: 10.7270/Q28P60KW
					More data for this Ligand-Target Pair