Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'tatsuoka' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167871 (3-Chloro-4-{4-[5-(4-methyl-pyrimidin-2-yl)-3,4-dih...) Show SMILES Cc1ccnc(n1)C1=CN(CCCCN2C(Cl)=COc3ccccc3C2=O)CCC1 |c:17,t:8| Show InChI InChI=1S/C23H25ClN4O2/c1-17-10-11-25-22(26-17)18-7-6-13-27(15-18)12-4-5-14-28-21(24)16-30-20-9-3-2-8-19(20)23(28)29/h2-3,8-11,15-16H,4-7,12-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.185	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097342 (3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ccccn1 |c:22,t:1| Show InChI InChI=1S/C23H24ClN3O2/c24-22-17-29-21-9-2-1-7-19(21)23(28)27(22)14-6-5-13-26-15-10-18(11-16-26)20-8-3-4-12-25-20/h1-4,7-10,12,17H,5-6,11,13-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097341 (3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097341 (3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167872 (3-Chloro-4-[4-(4-pyrimidin-2-yl-3,6-dihydro-2H-pyr...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ncccn1 |c:22,t:1| Show InChI InChI=1S/C22H23ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-8,10-11,16H,3-4,9,12-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097343 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.59	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097343 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167869 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperidin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-7,10-11,16-17H,3-4,8-9,12-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.81	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097345 (3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H27N5O2/c1-18-17-29-20-8-3-2-7-19(20)21(28)27(18)12-5-4-11-25-13-15-26(16-14-25)22-23-9-6-10-24-22/h2-3,6-10,17H,4-5,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50097344 (4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)C=COc2ccccc12 |c:21| Show InChI InChI=1S/C21H25N5O2/c27-20-18-6-1-2-7-19(18)28-17-16-25(20)11-4-3-10-24-12-14-26(15-13-24)21-22-8-5-9-23-21/h1-2,5-9,16-17H,3-4,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097341 (3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097341 (3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167870 (3-Chloro-4-[4-(5-pyrimidin-2-yl-3,6-dihydro-2H-pyr...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC=C(C1)c1ncccn1 |c:22,t:1| Show InChI InChI=1S/C22H23ClN4O2/c23-20-16-29-19-9-2-1-8-18(19)22(28)27(20)14-4-3-12-26-13-5-7-17(15-26)21-24-10-6-11-25-21/h1-2,6-11,16H,3-5,12-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.6	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097342 (3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ccccn1 |c:22,t:1| Show InChI InChI=1S/C23H24ClN3O2/c24-22-17-29-21-9-2-1-7-19(21)23(28)27(22)14-6-5-13-26-15-10-18(11-16-26)20-8-3-4-12-25-20/h1-4,7-10,12,17H,5-6,11,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011937 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCCCCCn2ccnc2)cc1O Show InChI InChI=1S/C21H25N3O4/c22-15-18(13-17-7-8-19(25)20(26)14-17)21(27)28-12-6-4-2-1-3-5-10-24-11-9-23-16-24/h7-9,11,13-14,16,25-26H,1-6,10,12H2/b18-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097343 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097343 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167874 (3-Chloro-4-[4-(3-pyrimidin-2-yl-piperidin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCCC(C1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-16-29-19-9-2-1-8-18(19)22(28)27(20)14-4-3-12-26-13-5-7-17(15-26)21-24-10-6-11-25-21/h1-2,6,8-11,16-17H,3-5,7,12-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011932 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...) Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011934 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011933 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Rattus norvegicus)	BDBM50011936 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O Show InChI InChI=1S/C18H16N2O4/c19-11-15(9-14-5-6-16(21)17(22)10-14)18(23)24-8-2-4-13-3-1-7-20-12-13/h1,3,5-7,9-10,12,21-22H,2,4,8H2/b15-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasma				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50167872 (3-Chloro-4-[4-(4-pyrimidin-2-yl-3,6-dihydro-2H-pyr...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ncccn1 |c:22,t:1| Show InChI InChI=1S/C22H23ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-8,10-11,16H,3-4,9,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	494	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011938 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50167871 (3-Chloro-4-{4-[5-(4-methyl-pyrimidin-2-yl)-3,4-dih...) Show SMILES Cc1ccnc(n1)C1=CN(CCCCN2C(Cl)=COc3ccccc3C2=O)CCC1 |c:17,t:8| Show InChI InChI=1S/C23H25ClN4O2/c1-17-10-11-25-22(26-17)18-7-6-13-27(15-18)12-4-5-14-28-21(24)16-30-20-9-3-2-8-19(20)23(28)29/h2-3,8-11,15-16H,4-7,12-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	763	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50167870 (3-Chloro-4-[4-(5-pyrimidin-2-yl-3,6-dihydro-2H-pyr...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC=C(C1)c1ncccn1 |c:22,t:1| Show InChI InChI=1S/C22H23ClN4O2/c23-20-16-29-19-9-2-1-8-18(19)22(28)27(20)14-4-3-12-26-13-5-7-17(15-26)21-24-10-6-11-25-21/h1-2,6-11,16H,3-5,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	893	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50097345 (3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...) Show SMILES CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H27N5O2/c1-18-17-29-20-8-3-2-7-19(20)21(28)27(18)12-5-4-11-25-13-15-26(16-14-25)22-23-9-6-10-24-22/h2-3,6-10,17H,4-5,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Biomedical Research Limited Curated by ChEMBL					Assay Description Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand				Bioorg Med Chem Lett 11: 595-8 (2001) BindingDB Entry DOI: 10.7270/Q2P26XDB
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011930 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus)	BDBM50011935 (2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...) Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50167869 (3-Chloro-4-[4-(4-pyrimidin-2-yl-piperidin-1-yl)-bu...) Show SMILES ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(CC1)c1ncccn1 |t:1| Show InChI InChI=1S/C22H25ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-7,10-11,16-17H,3-4,8-9,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50011931 ((2E)‐3‐phenylprop‐2‐enR...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytes				J Med Chem 34: 1503-5 (1991) BindingDB Entry DOI: 10.7270/Q22Z14G6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50167873 (3-Chloro-4-[4-(4-hydroxy-4-pyrimidin-2-yl-piperidi...) Show SMILES OC1(CCN(CCCCN2C(Cl)=COc3ccccc3C2=O)CC1)c1ncccn1 |c:11| Show InChI InChI=1S/C22H25ClN4O3/c23-19-16-30-18-7-2-1-6-17(18)20(28)27(19)13-4-3-12-26-14-8-22(29,9-15-26)21-24-10-5-11-25-21/h1-2,5-7,10-11,16,29H,3-4,8-9,12-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Suntory Biomedical Research Co., Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 15: 2990-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.059 BindingDB Entry DOI: 10.7270/Q21Z456V
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50263669 ((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...) Show SMILES O=NC1[C@@H]2C[C@@]2(Oc2ccccc12)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,15H,10H2,(H,18,20)/t13-,15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.				Bioorg Med Chem Lett 6: 763-766 (1996) Article DOI: 10.1016/0960-894X(96)00104-7 BindingDB Entry DOI: 10.7270/Q2WS8T7Q
					More data for this Ligand-Target Pair

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