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Compile Data Set for Download or QSAR

Found 23 hits with Last Name = 'nguyen' and Initial = 'ta'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537869
PNG
(CHEMBL4638367)
Show SMILES Oc1ccc(cc1)[C@@H]1Oc2ccc(\C=C\c3cc(O)cc(O)c3O)cc2[C@H]1c1cc(O)cc(O)c1O |r|
Show InChI InChI=1S/C28H22O8/c29-17-6-4-15(5-7-17)28-25(21-11-19(31)13-23(33)27(21)35)20-9-14(2-8-24(20)36-28)1-3-16-10-18(30)12-22(32)26(16)34/h1-13,25,28-35H/b3-1+/t25-,28-/m0/s1
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 920n/an/an/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate by Dixon plot analysis

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537867
PNG
(CHEMBL4649760)
Show SMILES Oc1ccc(cc1)[C@H]1Oc2ccc(\C=C\c3cc(O)cc(O)c3O)cc2[C@@H]1c1cc(O)cc(O)c1O |r|
Show InChI InChI=1S/C28H22O8/c29-17-6-4-15(5-7-17)28-25(21-11-19(31)13-23(33)27(21)35)20-9-14(2-8-24(20)36-28)1-3-16-10-18(30)12-22(32)26(16)34/h1-13,25,28-35H/b3-1+/t25-,28-/m1/s1
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 1.02E+3n/an/an/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate by Dixon plot analysis

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537869
PNG
(CHEMBL4638367)
Show SMILES Oc1ccc(cc1)[C@@H]1Oc2ccc(\C=C\c3cc(O)cc(O)c3O)cc2[C@H]1c1cc(O)cc(O)c1O |r|
Show InChI InChI=1S/C28H22O8/c29-17-6-4-15(5-7-17)28-25(21-11-19(31)13-23(33)27(21)35)20-9-14(2-8-24(20)36-28)1-3-16-10-18(30)12-22(32)26(16)34/h1-13,25,28-35H/b3-1+/t25-,28-/m0/s1
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n/an/a 1.90E+3n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537867
PNG
(CHEMBL4649760)
Show SMILES Oc1ccc(cc1)[C@H]1Oc2ccc(\C=C\c3cc(O)cc(O)c3O)cc2[C@@H]1c1cc(O)cc(O)c1O |r|
Show InChI InChI=1S/C28H22O8/c29-17-6-4-15(5-7-17)28-25(21-11-19(31)13-23(33)27(21)35)20-9-14(2-8-24(20)36-28)1-3-16-10-18(30)12-22(32)26(16)34/h1-13,25,28-35H/b3-1+/t25-,28-/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50148911
PNG
((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9|
Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537874
PNG
(CHEMBL4647539)
Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2O)cc1
Show InChI InChI=1S/C14H12O4/c15-11-5-2-9(3-6-11)1-4-10-7-12(16)8-13(17)14(10)18/h1-8,15-18H/b4-1+
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n/an/a 1.21E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50391109
PNG
(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)
Show SMILES [O-][V]([O-])([O-])=O
Show InChI InChI=1S/4O.V/q;3*-1;
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n/an/a 1.51E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537871
PNG
(CHEMBL4639409)
Show SMILES COc1cc(\C=C\C(=O)O[C@H]2[C@H](O)[C@@H](CO)O[C@@H](Oc3c(O)cc(O)cc3\C=C\c3ccc(O)cc3)[C@@H]2O)ccc1O |r|
Show InChI InChI=1S/C30H30O12/c1-39-23-12-17(5-10-21(23)34)6-11-25(36)41-29-26(37)24(15-31)40-30(27(29)38)42-28-18(13-20(33)14-22(28)35)7-2-16-3-8-19(32)9-4-16/h2-14,24,26-27,29-35,37-38H,15H2,1H3/b7-2+,11-6+/t24-,26-,27-,29+,30+/m1/s1
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n/an/a 2.74E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537866
PNG
(CHEMBL4636723)
Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc3O[C@@H]([C@H](c3c2)c2cc(O)cc(O)c2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C40H42O18/c41-14-27-30(48)32(50)34(52)39(55-27)57-36-18(10-20(44)12-24(36)46)3-1-16-2-8-26-22(9-16)29(37(54-26)17-4-6-19(43)7-5-17)23-11-21(45)13-25(47)38(23)58-40-35(53)33(51)31(49)28(15-42)56-40/h1-13,27-35,37,39-53H,14-15H2/b3-1+/t27-,28-,29-,30-,31-,32+,33+,34-,35-,37-,39+,40+/m1/s1
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n/an/a 3.22E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537868
PNG
(CHEMBL4639813)
Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc3O[C@H]([C@@H](c3c2)c2cc(O)cc(O)c2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C40H42O18/c41-14-27-30(48)32(50)34(52)39(55-27)57-36-18(10-20(44)12-24(36)46)3-1-16-2-8-26-22(9-16)29(37(54-26)17-4-6-19(43)7-5-17)23-11-21(45)13-25(47)38(23)58-40-35(53)33(51)31(49)28(15-42)56-40/h1-13,27-35,37,39-53H,14-15H2/b3-1+/t27-,28-,29+,30-,31-,32+,33+,34-,35-,37+,39+,40+/m1/s1
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n/an/a 3.49E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537870
PNG
(CHEMBL4647374)
Show SMILES CC(=O)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@@H]1O |r|
Show InChI InChI=1S/C22H24O10/c1-11(24)30-21-18(28)17(10-23)31-22(19(21)29)32-20-13(8-15(26)9-16(20)27)5-2-12-3-6-14(25)7-4-12/h2-9,17-19,21-23,25-29H,10H2,1H3/b5-2+/t17-,18-,19-,21+,22+/m1/s1
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n/an/a 3.76E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537875
PNG
(CHEMBL4643421)
Show SMILES OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)cc(O)cc3\C=C\c3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C26H32O14/c27-9-16-18(31)20(33)22(35)25(38-16)37-10-17-19(32)21(34)23(36)26(39-17)40-24-12(7-14(29)8-15(24)30)4-1-11-2-5-13(28)6-3-11/h1-8,16-23,25-36H,9-10H2/b4-1+/t16-,17-,18-,19-,20+,21+,22-,23-,25-,26+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537876
PNG
(CHEMBL4647457)
Show SMILES CC(=O)OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C22H24O10/c1-11(23)30-10-17-18(27)19(28)20(29)22(31-17)32-21-13(8-15(25)9-16(21)26)5-2-12-3-6-14(24)7-4-12/h2-9,17-20,22,24-29H,10H2,1H3/b5-2+/t17-,18-,19+,20-,22+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537877
PNG
(CHEMBL4648424)
Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C27H26O13/c28-11-20-22(35)23(36)25(39-26(37)14-8-17(31)21(34)18(32)9-14)27(38-20)40-24-13(7-16(30)10-19(24)33)4-1-12-2-5-15(29)6-3-12/h1-10,20,22-23,25,27-36H,11H2/b4-1+/t20-,22-,23+,25-,27+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537878
PNG
(CHEMBL4649674)
Show SMILES COc1cc(\C=C\C(=O)O[C@H]2[C@H](Oc3c(O)cc(O)cc3\C=C\c3ccc(O)cc3)O[C@H](CO)[C@@H](O)[C@@H]2O)ccc1O |r|
Show InChI InChI=1S/C30H30O12/c1-39-23-12-17(5-10-21(23)34)6-11-25(36)41-29-27(38)26(37)24(15-31)40-30(29)42-28-18(13-20(33)14-22(28)35)7-2-16-3-8-19(32)9-4-16/h2-14,24,26-27,29-35,37-38H,15H2,1H3/b7-2+,11-6+/t24-,26-,27+,29-,30+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537873
PNG
(CHEMBL4633335)
Show SMILES COc1cc(ccc1O)[C@@H]1CC(=O)Oc2cc(O)c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(\C=C\c3ccc(O)cc3)c12 |r|
Show InChI InChI=1S/C30H30O12/c1-39-21-10-15(5-9-19(21)33)18-11-24(35)40-22-12-20(34)29(42-30-28(38)27(37)26(36)23(13-31)41-30)17(25(18)22)8-4-14-2-6-16(32)7-3-14/h2-10,12,18,23,26-28,30-34,36-38H,11,13H2,1H3/b8-4+/t18-,23+,26+,27-,28+,30-/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537879
PNG
(CHEMBL4641043)
Show SMILES O[C@@H]1CO[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H20O8/c20-12-5-2-10(3-6-12)1-4-11-7-13(21)8-14(22)18(11)27-19-17(25)16(24)15(23)9-26-19/h1-8,15-17,19-25H,9H2/b4-1+/t15-,16+,17-,19+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537880
PNG
(CHEMBL4647972)
Show SMILES C[C@@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C20H22O8/c1-10-16(24)17(25)18(26)20(27-10)28-19-12(8-14(22)9-15(19)23)5-2-11-3-6-13(21)7-4-11/h2-10,16-18,20-26H,1H3/b5-2+/t10-,16-,17+,18+,20-/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537881
PNG
(CHEMBL4210319)
Show SMILES OC(=O)c1cc(O)cc(O)c1C(=O)Cc1ccc(O)cc1
Show InChI InChI=1S/C15H12O6/c16-9-3-1-8(2-4-9)5-12(18)14-11(15(20)21)6-10(17)7-13(14)19/h1-4,6-7,16-17,19H,5H2,(H,20,21)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537865
PNG
(CHEMBL4639639)
Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2[C@@H]2[C@H](Oc3cc(O)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(\C=C\c4ccc(O)cc4)c23)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C40H42O18/c41-14-26-30(48)32(50)34(52)39(55-26)57-37-21(10-3-16-1-6-18(43)7-2-16)28-25(13-24(37)47)54-36(17-4-8-19(44)9-5-17)29(28)22-11-20(45)12-23(46)38(22)58-40-35(53)33(51)31(49)27(15-42)56-40/h1-13,26-27,29-36,39-53H,14-15H2/b10-3+/t26-,27-,29+,30-,31-,32+,33+,34-,35-,36-,39+,40+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50537872
PNG
(CHEMBL4635601)
Show SMILES O[C@@H]1[C@@H](COC=O)O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C21H22O10/c22-10-29-9-16-17(26)18(27)19(28)21(30-16)31-20-12(7-14(24)8-15(20)25)4-1-11-2-5-13(23)6-3-11/h1-8,10,16-19,21,23-28H,9H2/b4-1+/t16-,17-,18+,19-,21+/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50020713
PNG
(CHEMBL460860)
Show SMILES OC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/m1/s1
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PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM23926
PNG
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyungpook National University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...

J Nat Prod 83: 323-332 (2020)


Article DOI: 10.1021/acs.jnatprod.9b00777
BindingDB Entry DOI: 10.7270/Q2GM8BVJ
More data for this
Ligand-Target Pair