Found 99 hits with Last Name = 'pallin' and Initial = 'td' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559562
(CHEMBL4762834)Show SMILES Cn1c(CNC(=O)C2(CC(O)=O)Cc3ccccc3C2)nc2ccccc12 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559561
(CHEMBL4760006) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559558
(CHEMBL4764936)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCCc1cc2ccccc2s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559551
(CHEMBL4758612)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1nc(cs1)-c1ccccc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559577
(CHEMBL4797456) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559576
(CHEMBL4794850)Show SMILES CC(NC(=O)CC1(Cc2ccccc2C1)C(O)=O)c1cc2ccccc2o1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559575
(CHEMBL4798439)Show SMILES Cc1ccc2oc(CNC(=O)CC3(Cc4ccccc4C3)C(O)=O)cc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559574
(CHEMBL4785438)Show SMILES Cc1ccc2oc(CNC(=O)C3(CC(O)=O)Cc4ccccc4C3)cc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559573
(CHEMBL4741361) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559572
(CHEMBL4747047) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559571
(CHEMBL4793389)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1ccc2ccccc2n1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559570
(CHEMBL4760832) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559569
(CHEMBL4761199) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559568
(CHEMBL4748733)Show SMILES C[C@H](NC(=O)C1(CC(O)=O)Cc2ccccc2C1)c1cc2ccccc2o1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559567
(CHEMBL4760989)Show SMILES C[C@@H](NC(=O)C1(CC(O)=O)Cc2ccccc2C1)c1cc2ccccc2o1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559566
(CHEMBL4749721) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559565
(CHEMBL4776453)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1cc2ccccc2[nH]1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559564
(CHEMBL4746167)Show SMILES Cn1c(CNC(=O)C2(CC(O)=O)Cc3ccccc3C2)cc2ccccc12 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559563
(CHEMBL4776454)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1nc2ccccc2[nH]1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559552
(CHEMBL4776002) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559560
(CHEMBL4756804)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1c[nH]c2ccccc12 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559559
(CHEMBL4746129)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCCc1cc2ccccc2o1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559557
(CHEMBL4794689)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCCc1cc2ccccc2[nH]1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559556
(CHEMBL4749889)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCCc1nc2ccccc2[nH]1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559555
(CHEMBL4745988)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCCc1nc2ccccc2s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559554
(CHEMBL4751454) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559553
(CHEMBL4745918)Show SMILES OC(=O)CC1(Cc2ccccc2C1)C(=O)NCc1ncc(s1)-c1ccccc1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50559578
(CHEMBL4751618) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rabbit ACE using Abz-FRK(DNP)-P as substrate measured for every 30 sec for 5 mins by UV-fluorescence based assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00554 BindingDB Entry DOI: 10.7270/Q2X63RNT |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319324
(1-(3,4-dimethoxyphenyl)-2-(1-m-tolyl-1H-tetrazol-5...)Show InChI InChI=1S/C19H19N3O3S/c1-13-5-4-6-15(9-13)22-19(11-20-21-22)26-12-16(23)14-7-8-17(24-2)18(10-14)25-3/h4-11H,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319333
(3-(1-(3-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-7-4-8-15(11-14)21-16(12-19-20-21)9-10-17(22)13-5-2-1-3-6-13/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319316
(1-(3,4-dimethoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-...)Show InChI InChI=1S/C18H17N3O3S/c1-23-16-9-8-13(10-17(16)24-2)15(22)12-25-18-11-19-20-21(18)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319331
(2-(1-cyclohexyl-1H-tetrazol-5-ylthio)-1-(3,4-dimet...)Show InChI InChI=1S/C18H23N3O3S/c1-23-16-9-8-13(10-17(16)24-2)15(22)12-25-18-11-19-20-21(18)14-6-4-3-5-7-14/h8-11,14H,3-7,12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319360
(1-(3-methoxyphenyl)-3-(1-phenyl-1H-tetrazol-5-yl)p...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-9-5-6-14(12-17)18(22)11-10-16-13-19-20-21(16)15-7-3-2-4-8-15/h2-9,12-13H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319310
(3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylthio)buta...)Show InChI InChI=1S/C14H17N3OS/c1-14(2,3)12(18)10-19-13-9-15-16-17(13)11-7-5-4-6-8-11/h4-9H,10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319311
(1-phenyl-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone...)Show InChI InChI=1S/C16H13N3OS/c20-15(13-7-3-1-4-8-13)12-21-16-11-17-18-19(16)14-9-5-2-6-10-14/h1-11H,12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319317
(1-phenyl-3-(1-phenyl-1H-tetrazol-5-ylthio)propan-2...)Show InChI InChI=1S/C17H15N3OS/c21-16(11-14-7-3-1-4-8-14)13-22-17-12-18-19-20(17)15-9-5-2-6-10-15/h1-10,12H,11,13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319343
(3-(1-(3-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylp...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-9-5-8-15(12-17)21-16(13-19-20-21)10-11-18(22)14-6-3-2-4-7-14/h2-9,12-13H,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319358
(1-(3-chlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)pr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-6-4-5-13(11-14)17(22)10-9-16-12-19-20-21(16)15-7-2-1-3-8-15/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319341
(1-phenyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one...)Show InChI InChI=1S/C17H15N3O/c21-17(14-7-3-1-4-8-14)12-11-16-13-18-19-20(16)15-9-5-2-6-10-15/h1-10,13H,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319344
(3-(1-(4-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylp...)Show InChI InChI=1S/C18H17N3O2/c1-23-17-10-7-15(8-11-17)21-16(13-19-20-21)9-12-18(22)14-5-3-2-4-6-14/h2-8,10-11,13H,9,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319318
(1-(furan-2-yl)-2-(1-phenyl-1H-tetrazol-5-ylthio)et...)Show InChI InChI=1S/C14H11N3O2S/c18-12(13-7-4-8-19-13)10-20-14-9-15-16-17(14)11-5-2-1-3-6-11/h1-9H,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 485 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319365
(3-(5-(4-methoxyphenyl)-1H-tetrazol-1-yl)-1-phenylp...)Show InChI InChI=1S/C17H16N4O2/c1-23-15-9-7-14(8-10-15)17-18-19-20-21(17)12-11-16(22)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 493 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319362
(1-cyclohexyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1...)Show InChI InChI=1S/C16H20N4O/c21-15(13-7-3-1-4-8-13)11-12-16-17-18-19-20(16)14-9-5-2-6-10-14/h2,5-6,9-10,13H,1,3-4,7-8,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 506 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319359
(1-(4-dichlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)...)Show InChI InChI=1S/C17H14ClN3O/c18-14-8-6-13(7-9-14)17(22)11-10-16-12-19-20-21(16)15-4-2-1-3-5-15/h1-9,12H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 539 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319332
(3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpr...)Show InChI InChI=1S/C17H14ClN3O/c18-14-6-8-15(9-7-14)21-16(12-19-20-21)10-11-17(22)13-4-2-1-3-5-13/h1-9,12H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 575 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319334
(1-phenyl-3-(1-p-tolyl-1H-tetrazol-5-yl)propan-1-on...)Show InChI InChI=1S/C18H17N3O/c1-14-7-9-16(10-8-14)21-17(13-19-20-21)11-12-18(22)15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 588 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319356
(1-(3-fluorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)pr...)Show InChI InChI=1S/C17H14FN3O/c18-14-6-4-5-13(11-14)17(22)10-9-16-12-19-20-21(16)15-7-2-1-3-8-15/h1-8,11-12H,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 597 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319336
(1-phenyl-3-(1-o-tolyl-1H-tetrazol-5-yl)propan-1-on...)Show InChI InChI=1S/C17H16N4O/c1-13-7-5-6-10-15(13)21-17(18-19-20-21)12-11-16(22)14-8-3-2-4-9-14/h2-10H,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 683 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319345
(4-(5-(3-oxo-3-phenylpropyl)-1H-tetrazol-1-yl)benzo...)Show InChI InChI=1S/C18H14N4O/c19-12-14-6-8-16(9-7-14)22-17(13-20-21-22)10-11-18(23)15-4-2-1-3-5-15/h1-9,13H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 686 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50319366
(3-(5-(benzo[d][1,3]dioxol-5-yl)-1H-tetrazol-1-yl)-...)Show InChI InChI=1S/C17H14N4O3/c22-14(12-4-2-1-3-5-12)8-9-21-17(18-19-20-21)13-6-7-15-16(10-13)24-11-23-15/h1-7,10H,8-9,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 722 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by ChEMBL
| Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3265-71 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ |
More data for this Ligand-Target Pair | |