Compile Data Set for Download or QSAR

Found 328 hits with Last Name = 'chou' and Initial = 'tf'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50587862 (CHEMBL5206855) Show SMILES CC(C)NCCC#Cc1ccc(OCc2cnc(SC3CCCC3)n2-c2cccnc2)cc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113446 BindingDB Entry DOI: 10.7270/Q24Q7ZXF
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50514004 (CHEMBL4476693) Show SMILES [2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(Sc2ncc(COc3cc(F)c(cc3F)C#CCOC(=O)NC3CCN(C)CC3)n2-c2cccnc2)C1([2H])[2H] Show InChI InChI=1S/C30H33F2N5O3S/c1-36-13-10-22(11-14-36)35-30(38)39-15-5-6-21-16-27(32)28(17-26(21)31)40-20-24-19-34-29(41-25-8-2-3-9-25)37(24)23-7-4-12-33-18-23/h4,7,12,16-19,22,25H,2-3,8-11,13-15,20H2,1H3,(H,35,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113446 BindingDB Entry DOI: 10.7270/Q24Q7ZXF
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50500325 (Cb 5083 | Cb-5083) Show SMILES Cc1cc2c(cccc2n1-c1nc2CCOCc2c(NCc2ccccc2)n1)C(N)=O Show InChI InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9,12H,10-11,13-14H2,1H3,(H2,25,30)(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113446 BindingDB Entry DOI: 10.7270/Q24Q7ZXF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468106 (CHEMBL4280801 | US11247985, Table 3.49) Show SMILES CN1CCN(CC1)C1(CNC2CCN(CC2)c2cccc(c2)-c2cc3cc(F)ccc3[nH]2)CCC1 Show InChI InChI=1S/C29H38FN5/c1-33-14-16-35(17-15-33)29(10-3-11-29)21-31-25-8-12-34(13-9-25)26-5-2-4-22(19-26)28-20-23-18-24(30)6-7-27(23)32-28/h2,4-7,18-20,25,31-32H,3,8-17,21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468110 (CHEMBL4288865 | US11247985, Table 3.67) Show SMILES CC(C)N1CCC(CC1)NC1CCN(CC1)c1cccc(c1)-c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C27H35FN4/c1-19(2)31-12-8-23(9-13-31)29-24-10-14-32(15-11-24)25-5-3-4-20(17-25)27-18-21-16-22(28)6-7-26(21)30-27/h3-7,16-19,23-24,29-30H,8-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468108 (CHEMBL4280125 | US11247985, Table 3.59) Show SMILES CC(C)N1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3cc(F)ccc3[nH]2)CC1 Show InChI InChI=1S/C28H38FN5/c1-21(2)33-16-14-32(15-17-33)13-10-30-25-8-11-34(12-9-25)26-5-3-4-22(19-26)28-20-23-18-24(29)6-7-27(23)31-28/h3-7,18-21,25,30-31H,8-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468112 (CHEMBL4277404 | US11247985, Table 3.63) Show SMILES CC(C)N1CCN(CC1)C1(CNC2CCN(CC2)c2cccc(c2)-c2cc3cc(F)ccc3[nH]2)COC1 Show InChI InChI=1S/C30H40FN5O/c1-22(2)34-12-14-36(15-13-34)30(20-37-21-30)19-32-26-8-10-35(11-9-26)27-5-3-4-23(17-27)29-18-24-16-25(31)6-7-28(24)33-29/h3-7,16-18,22,26,32-33H,8-15,19-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Spastin (Homo sapiens)	BDBM50587865 (CHEMBL5190401) Show SMILES CC(C)[C@@H]1CN(CCN1)c1nc(Nc2cc([nH]n2)C(C)(C)C)c2cc[nH]c2n1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113446 BindingDB Entry DOI: 10.7270/Q24Q7ZXF
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468123 (CHEMBL4291440 | US11247985, Table 3.97) Show SMILES CC(C)N1CCN(CC1)C1(CNC2CCN(CC2)c2cccc(c2)-c2cc3cc(F)ccc3[nH]2)CCC1 Show InChI InChI=1S/C31H42FN5/c1-23(2)35-15-17-37(18-16-35)31(11-4-12-31)22-33-27-9-13-36(14-10-27)28-6-3-5-24(20-28)30-21-25-19-26(32)7-8-29(25)34-30/h3,5-8,19-21,23,27,33-34H,4,9-18,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468118 (CHEMBL4280546 | US11247985, Table 3.1) Show SMILES CC(C)N1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3ccccc3[nH]2)CC1 Show InChI InChI=1S/C28H39N5/c1-22(2)32-18-16-31(17-19-32)15-12-29-25-10-13-33(14-11-25)26-8-5-7-23(20-26)28-21-24-6-3-4-9-27(24)30-28/h3-9,20-22,25,29-30H,10-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468115 (CHEMBL4278176 | US11247985, Table 3.117) Show SMILES CC(C)N1CCC(CC1)N[C@H]1CC[C@@H](CC1)c1cccc(c1)-c1cc2cc(F)ccc2[nH]1 |r,wU:13.17,wD:10.10,(52.21,-2.26,;51.43,-3.58,;52.19,-4.92,;49.89,-3.58,;49.13,-2.23,;47.59,-2.23,;46.81,-3.53,;47.56,-4.87,;49.1,-4.87,;45.28,-3.53,;44.49,-4.83,;42.95,-4.83,;42.18,-6.15,;42.94,-7.49,;44.47,-7.49,;45.26,-6.18,;42.16,-8.82,;42.93,-10.16,;42.16,-11.49,;40.62,-11.49,;39.85,-10.14,;40.62,-8.82,;38.31,-10.14,;37.41,-11.4,;35.94,-10.92,;34.6,-11.68,;33.27,-10.91,;31.94,-11.69,;33.27,-9.37,;34.6,-8.59,;35.94,-9.37,;37.41,-8.89,)| Show InChI InChI=1S/C28H36FN3/c1-19(2)32-14-12-26(13-15-32)30-25-9-6-20(7-10-25)21-4-3-5-22(16-21)28-18-23-17-24(29)8-11-27(23)31-28/h3-5,8,11,16-20,25-26,30-31H,6-7,9-10,12-15H2,1-2H3/t20-,25-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468116 (CHEMBL4276697 | US11247985, Table 3.91) Show SMILES CC(C)N1CCN(CC1)C(=O)CCNC1CCN(CC1)c1cccc(c1)-c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C29H38FN5O/c1-21(2)33-14-16-35(17-15-33)29(36)8-11-31-25-9-12-34(13-10-25)26-5-3-4-22(19-26)28-20-23-18-24(30)6-7-27(23)32-28/h3-7,18-21,25,31-32H,8-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264457 (CHEMBL4080490) Show SMILES Fc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(F)cc4)cccc3c2)cc1 Show InChI InChI=1S/C34H24F2N4O2S2/c35-27-11-7-21(8-12-27)17-39-33(41)25-15-23-3-1-5-29(31(23)37-19-25)43-44-30-6-2-4-24-16-26(20-38-32(24)30)34(42)40-18-22-9-13-28(36)14-10-22/h1-16,19-20H,17-18H2,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468122 (CHEMBL4291849 | US11247985, Table 3.15) Show SMILES CCN1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3ccccc3[nH]2)CC1 Show InChI InChI=1S/C27H37N5/c1-2-30-16-18-31(19-17-30)15-12-28-24-10-13-32(14-11-24)25-8-5-7-22(20-25)27-21-23-6-3-4-9-26(23)29-27/h3-9,20-21,24,28-29H,2,10-19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264417 (CHEMBL4104719) Show SMILES O=C(NCc1ccncc1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccncc3)cccc2c1 Show InChI InChI=1S/C32H24N6O2S2/c39-31(37-17-21-7-11-33-12-8-21)25-15-23-3-1-5-27(29(23)35-19-25)41-42-28-6-2-4-24-16-26(20-36-30(24)28)32(40)38-18-22-9-13-34-14-10-22/h1-16,19-20H,17-18H2,(H,37,39)(H,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264455 (CHEMBL4060337) Show SMILES O=C(NCc1ccc2OCOc2c1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc4OCOc4c3)cccc2c1 Show InChI InChI=1S/C36H26N4O6S2/c41-35(39-15-21-7-9-27-29(11-21)45-19-43-27)25-13-23-3-1-5-31(33(23)37-17-25)47-48-32-6-2-4-24-14-26(18-38-34(24)32)36(42)40-16-22-8-10-28-30(12-22)46-20-44-28/h1-14,17-18H,15-16,19-20H2,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50562854 (CHEMBL4763993) Show SMILES Cc1ccc(cc1)C(=O)C#Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113148 BindingDB Entry DOI: 10.7270/Q2HT2T24
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264415 (CHEMBL4096289) Show SMILES COc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(OC)cc4)cccc3c2)cc1 Show InChI InChI=1S/C36H30N4O4S2/c1-43-29-13-9-23(10-14-29)19-39-35(41)27-17-25-5-3-7-31(33(25)37-21-27)45-46-32-8-4-6-26-18-28(22-38-34(26)32)36(42)40-20-24-11-15-30(44-2)16-12-24/h3-18,21-22H,19-20H2,1-2H3,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468105 (CHEMBL4288427 | US11247985, Table 3.99) Show SMILES CC(C)(C)N1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3ccccc3[nH]2)CC1 Show InChI InChI=1S/C29H41N5/c1-29(2,3)34-19-17-32(18-20-34)16-13-30-25-11-14-33(15-12-25)26-9-6-8-23(21-26)28-22-24-7-4-5-10-27(24)31-28/h4-10,21-22,25,30-31H,11-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468109 (CHEMBL4283987 | US11247985, Table 3.13) Show SMILES CN1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3ccccc3[nH]2)CC1 Show InChI InChI=1S/C26H35N5/c1-29-15-17-30(18-16-29)14-11-27-23-9-12-31(13-10-23)24-7-4-6-21(19-24)26-20-22-5-2-3-8-25(22)28-26/h2-8,19-20,23,27-28H,9-18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264482 (CHEMBL4086748) Show SMILES COC(=O)CNC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCC(=O)OC)cccc2c1 Show InChI InChI=1S/C26H22N4O6S2/c1-35-21(31)13-29-25(33)17-9-15-5-3-7-19(23(15)27-11-17)37-38-20-8-4-6-16-10-18(12-28-24(16)20)26(34)30-14-22(32)36-2/h3-12H,13-14H2,1-2H3,(H,29,33)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264420 (CHEMBL4100384) Show SMILES O=C(NCCc1cccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCCc3cccs3)cccc2c1 Show InChI InChI=1S/C32H26N4O2S4/c37-31(33-13-11-25-7-3-15-39-25)23-17-21-5-1-9-27(29(21)35-19-23)41-42-28-10-2-6-22-18-24(20-36-30(22)28)32(38)34-14-12-26-8-4-16-40-26/h1-10,15-20H,11-14H2,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
COP9 signalosome complex subunit 5 (Homo sapiens (Human))	BDBM50264453 (CHEMBL4088568) Show SMILES O=C(NCc1ccc(cc1)N1CCCCC1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc(cc3)N3CCOCC3)cccc2c1 Show InChI InChI=1S/C43H42N6O3S2/c50-42(46-26-30-10-14-36(15-11-30)48-18-2-1-3-19-48)34-24-32-6-4-8-38(40(32)44-28-34)53-54-39-9-5-7-33-25-35(29-45-41(33)39)43(51)47-27-31-12-16-37(17-13-31)49-20-22-52-23-21-49/h4-17,24-25,28-29H,1-3,18-23,26-27H2,(H,46,50)(H,47,51)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468121 (CHEMBL4293387 | US11247985, Table 3.131) Show SMILES C(CN1CCNCC1)NC1CCN(CC1)c1cccc(c1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C25H33N5/c1-2-7-24-21(4-1)19-25(28-24)20-5-3-6-23(18-20)30-13-8-22(9-14-30)27-12-17-29-15-10-26-11-16-29/h1-7,18-19,22,26-28H,8-17H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468117 (CHEMBL4290763 | US11247985, Table 3.147) Show SMILES CC(C)N1CCN(CCCNC2CCN(CC2)c2cccc(c2)-c2cc3ccccc3[nH]2)CC1 Show InChI InChI=1S/C29H41N5/c1-23(2)33-19-17-32(18-20-33)14-6-13-30-26-11-15-34(16-12-26)27-9-5-8-24(21-27)29-22-25-7-3-4-10-28(25)31-29/h3-5,7-10,21-23,26,30-31H,6,11-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264419 (CHEMBL4073553) Show SMILES O=C(NCCc1nccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCCc3nccs3)cccc2c1 Show InChI InChI=1S/C30H24N6O2S4/c37-29(33-9-7-25-31-11-13-39-25)21-15-19-3-1-5-23(27(19)35-17-21)41-42-24-6-2-4-20-16-22(18-36-28(20)24)30(38)34-10-8-26-32-12-14-40-26/h1-6,11-18H,7-10H2,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264515 (CHEMBL4070821) Show SMILES O=C(Nc1nccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)Nc3nccs3)cccc2c1 Show InChI InChI=1S/C26H16N6O2S4/c33-23(31-25-27-7-9-35-25)17-11-15-3-1-5-19(21(15)29-13-17)37-38-20-6-2-4-16-12-18(14-30-22(16)20)24(34)32-26-28-8-10-36-26/h1-14H,(H,27,31,33)(H,28,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264471 (CHEMBL4093962) Show SMILES O=C(NCc1nccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3nccs3)cccc2c1 Show InChI InChI=1S/C28H20N6O2S4/c35-27(33-15-23-29-7-9-37-23)19-11-17-3-1-5-21(25(17)31-13-19)39-40-22-6-2-4-18-12-20(14-32-26(18)22)28(36)34-16-24-30-8-10-38-24/h1-14H,15-16H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
COP9 signalosome complex subunit 5 (Homo sapiens (Human))	BDBM50264415 (CHEMBL4096289) Show SMILES COc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(OC)cc4)cccc3c2)cc1 Show InChI InChI=1S/C36H30N4O4S2/c1-43-29-13-9-23(10-14-29)19-39-35(41)27-17-25-5-3-7-31(33(25)37-21-27)45-46-32-8-4-6-26-18-28(22-38-34(26)32)36(42)40-20-24-11-15-30(44-2)16-12-24/h3-18,21-22H,19-20H2,1-2H3,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
COP9 signalosome complex subunit 5 (Homo sapiens (Human))	BDBM50264426 (CHEMBL4095913) Show SMILES O=C(NCc1ccco1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccco3)cccc2c1 Show InChI InChI=1S/C30H22N4O4S2/c35-29(33-17-23-7-3-11-37-23)21-13-19-5-1-9-25(27(19)31-15-21)39-40-26-10-2-6-20-14-22(16-32-28(20)26)30(36)34-18-24-8-4-12-38-24/h1-16H,17-18H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264417 (CHEMBL4104719) Show SMILES O=C(NCc1ccncc1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccncc3)cccc2c1 Show InChI InChI=1S/C32H24N6O2S2/c39-31(37-17-21-7-11-33-12-8-21)25-15-23-3-1-5-27(29(23)35-19-25)41-42-28-6-2-4-24-16-26(20-36-30(24)28)32(40)38-18-22-9-13-34-14-10-22/h1-16,19-20H,17-18H2,(H,37,39)(H,38,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50562860 (CHEMBL4762311) Show SMILES CC(C)(C)n1nc(-c2ccccc2)c2c(NC(=O)C=C)ncnc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113148 BindingDB Entry DOI: 10.7270/Q2HT2T24
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264419 (CHEMBL4073553) Show SMILES O=C(NCCc1nccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCCc3nccs3)cccc2c1 Show InChI InChI=1S/C30H24N6O2S4/c37-29(33-9-7-25-31-11-13-39-25)21-15-19-3-1-5-23(27(19)35-17-21)41-42-24-6-2-4-20-16-22(18-36-28(20)24)30(38)34-10-8-26-32-12-14-40-26/h1-6,11-18H,7-10H2,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264415 (CHEMBL4096289) Show SMILES COc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(OC)cc4)cccc3c2)cc1 Show InChI InChI=1S/C36H30N4O4S2/c1-43-29-13-9-23(10-14-29)19-39-35(41)27-17-25-5-3-7-31(33(25)37-21-27)45-46-32-8-4-6-26-18-28(22-38-34(26)32)36(42)40-20-24-11-15-30(44-2)16-12-24/h3-18,21-22H,19-20H2,1-2H3,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50562857 (CHEMBL4791813) Show SMILES [O-][N+](=O)\C=C\c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113148 BindingDB Entry DOI: 10.7270/Q2HT2T24
					More data for this Ligand-Target Pair
Vacuolar protein sorting-associated protein 4B (Homo sapiens)	BDBM50514006 (CHEMBL4572843) Show SMILES Fc1ccc(cc1)C(CCCNCC1CCc2[nH]c3ccc(F)cc3c2C1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F3N2/c30-22-8-4-20(5-9-22)25(21-6-10-23(31)11-7-21)2-1-15-33-18-19-3-13-28-26(16-19)27-17-24(32)12-14-29(27)34-28/h4-12,14,17,19,25,33-34H,1-3,13,15-16,18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113446 BindingDB Entry DOI: 10.7270/Q24Q7ZXF
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264483 (CHEMBL4105598) Show SMILES O=C(NCc1cccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3cccs3)cccc2c1 Show InChI InChI=1S/C30H22N4O2S4/c35-29(33-17-23-7-3-11-37-23)21-13-19-5-1-9-25(27(19)31-15-21)39-40-26-10-2-6-20-14-22(16-32-28(20)26)30(36)34-18-24-8-4-12-38-24/h1-16H,17-18H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264453 (CHEMBL4088568) Show SMILES O=C(NCc1ccc(cc1)N1CCCCC1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc(cc3)N3CCOCC3)cccc2c1 Show InChI InChI=1S/C43H42N6O3S2/c50-42(46-26-30-10-14-36(15-11-30)48-18-2-1-3-19-48)34-24-32-6-4-8-38(40(32)44-28-34)53-54-39-9-5-7-33-25-35(29-45-41(33)39)43(51)47-27-31-12-16-37(17-13-31)49-20-22-52-23-21-49/h4-17,24-25,28-29H,1-3,18-23,26-27H2,(H,46,50)(H,47,51)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264416 (CHEMBL4069023) Show SMILES FC(F)(F)c1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(cc4)C(F)(F)F)cccc3c2)cc1 Show InChI InChI=1S/C36H24F6N4O2S2/c37-35(38,39)27-11-7-21(8-12-27)17-45-33(47)25-15-23-3-1-5-29(31(23)43-19-25)49-50-30-6-2-4-24-16-26(20-44-32(24)30)34(48)46-18-22-9-13-28(14-10-22)36(40,41)42/h1-16,19-20H,17-18H2,(H,45,47)(H,46,48)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468111 (CHEMBL4287346 | US11247985, Table 3.18) Show SMILES CN(C)CCNC1CCN(CC1)c1cccc(c1)-c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C23H29FN4/c1-27(2)13-10-25-20-8-11-28(12-9-20)21-5-3-4-17(15-21)23-16-18-14-19(24)6-7-22(18)26-23/h3-7,14-16,20,25-26H,8-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264426 (CHEMBL4095913) Show SMILES O=C(NCc1ccco1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccco3)cccc2c1 Show InChI InChI=1S/C30H22N4O4S2/c35-29(33-17-23-7-3-11-37-23)21-13-19-5-1-9-25(27(19)31-15-21)39-40-26-10-2-6-20-14-22(16-32-28(20)26)30(36)34-18-24-8-4-12-38-24/h1-16H,17-18H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50562869 (CHEMBL4759891) Show SMILES CC(C)(C)n1nc(-c2ccc(cc2)-c2ccccc2)c2c(ncnc12)N(C(=O)C=C)C(=O)C=C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113148 BindingDB Entry DOI: 10.7270/Q2HT2T24
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264453 (CHEMBL4088568) Show SMILES O=C(NCc1ccc(cc1)N1CCCCC1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc(cc3)N3CCOCC3)cccc2c1 Show InChI InChI=1S/C43H42N6O3S2/c50-42(46-26-30-10-14-36(15-11-30)48-18-2-1-3-19-48)34-24-32-6-4-8-38(40(32)44-28-34)53-54-39-9-5-7-33-25-35(29-45-41(33)39)43(51)47-27-31-12-16-37(17-13-31)49-20-22-52-23-21-49/h4-17,24-25,28-29H,1-3,18-23,26-27H2,(H,46,50)(H,47,51)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
STAM-binding protein (Homo sapiens (Human))	BDBM50264457 (CHEMBL4080490) Show SMILES Fc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(F)cc4)cccc3c2)cc1 Show InChI InChI=1S/C34H24F2N4O2S2/c35-27-11-7-21(8-12-27)17-39-33(41)25-15-23-3-1-5-29(31(23)37-19-25)43-44-30-6-2-4-24-16-26(20-38-32(24)30)34(42)40-18-22-9-13-28(36)14-10-22/h1-16,19-20H,17-18H2,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264455 (CHEMBL4060337) Show SMILES O=C(NCc1ccc2OCOc2c1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc4OCOc4c3)cccc2c1 Show InChI InChI=1S/C36H26N4O6S2/c41-35(39-15-21-7-9-27-29(11-21)45-19-43-27)25-13-23-3-1-5-31(33(23)37-17-25)47-48-32-6-2-4-24-14-26(18-38-34(24)32)36(42)40-16-22-8-10-28-30(12-22)46-20-44-28/h1-14,17-18H,15-16,19-20H2,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264426 (CHEMBL4095913) Show SMILES O=C(NCc1ccco1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccco3)cccc2c1 Show InChI InChI=1S/C30H22N4O4S2/c35-29(33-17-23-7-3-11-37-23)21-13-19-5-1-9-25(27(19)31-15-21)39-40-26-10-2-6-20-14-22(16-32-28(20)26)30(36)34-18-24-8-4-12-38-24/h1-16H,17-18H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264526 (CHEMBL4093473) Show SMILES COC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)OC)cccc2c1 Show InChI InChI=1S/C22H16N2O4S2/c1-27-21(25)15-9-13-5-3-7-17(19(13)23-11-15)29-30-18-8-4-6-14-10-16(22(26)28-2)12-24-20(14)18/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264491 (CHEMBL4101230) Show SMILES Cc1cc(S)c2ncccc2c1 Show InChI InChI=1S/C10H9NS/c1-7-5-8-3-2-4-11-10(8)9(12)6-7/h2-6,12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human))	BDBM50468104 (CHEMBL4276767 | US11247985, Table 3.23) Show SMILES Cn1ncnc1CCNC1CCN(CC1)c1cccc(c1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H28N6/c1-29-24(26-17-27-29)9-12-25-20-10-13-30(14-11-20)21-7-4-6-18(15-21)23-16-19-5-2-3-8-22(19)28-23/h2-8,15-17,20,25,28H,9-14H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Chemical Diversity Center Curated by ChEMBL					Assay Description Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...				ACS Med Chem Lett 9: 1075-1081 (2018) Article DOI: 10.1021/acsmedchemlett.8b00372 BindingDB Entry DOI: 10.7270/Q23F4SBJ
					More data for this Ligand-Target Pair
26S proteasome non-ATPase regulatory subunit 14 (Homo sapiens (Human))	BDBM50264547 (CHEMBL4077883) Show SMILES COC(=O)c1ccnc2c(SSc3cccc4c(ccnc34)C(=O)OC)cccc12 Show InChI InChI=1S/C22H16N2O4S2/c1-27-21(25)15-9-11-23-19-13(15)5-3-7-17(19)29-30-18-8-4-6-14-16(22(26)28-2)10-12-24-20(14)18/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 328 total )  |  Next  |  Last  >>

Jump to: