| Reaction Details |
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 | Report a problem with these data |
| Target | STAM-binding protein |
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| Ligand | BDBM50264455 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1698729 (CHEMBL4049711) |
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| IC50 | <200±n/a nM |
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| Citation |  Perez, C; Li, J; Parlati, F; Rouffet, M; Ma, Y; Mackinnon, AL; Chou, TF; Deshaies, RJ; Cohen, SM Discovery of an Inhibitor of the Proteasome Subunit Rpn11. J Med Chem60:1343-1361 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| STAM-binding protein |
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| Name: | STAM-binding protein |
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| Synonyms: | AMSH | STABP_HUMAN | STAM-binding protein (AMSH) | STAMBP |
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| Type: | Protein |
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| Mol. Mass.: | 48073.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95630 |
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| Residue: | 424 |
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| Sequence: | MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF
ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE
YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK
IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG
ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL
IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP
ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI
TDLR
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| BDBM50264455 |
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| n/a |
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| Name | BDBM50264455 |
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| Synonyms: | CHEMBL4060337 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H26N4O6S2 |
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| Mol. Mass. | 674.745 |
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| SMILES | O=C(NCc1ccc2OCOc2c1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccc4OCOc4c3)cccc2c1 |
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| Structure | 
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