Found 14 hits with Last Name = 'kilpatrick' and Initial = 'tj' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase Mer
(Homo sapiens (Human)) | BDBM308131
(US9649309, Compound UNC2876A)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.25,wD:27.29,(-10.11,-3.85,;-8.77,-3.08,;-7.44,-3.85,;-6.1,-3.08,;-4.77,-3.85,;-3.44,-3.08,;-2.1,-3.85,;-.77,-3.08,;-.77,-1.54,;.56,-.77,;.56,.77,;1.9,-1.54,;3.23,-.77,;4.56,-1.54,;5.9,-.77,;5.9,.77,;7.23,1.54,;8.57,.77,;9.34,-.56,;10.11,.77,;4.56,1.54,;3.23,.77,;-2.1,-.77,;-2.1,.77,;-3.44,1.54,;-4.77,.77,;-6.1,1.54,;-6.1,3.08,;-7.44,3.85,;-4.77,3.85,;-3.44,3.08,;-3.44,-1.54,)| Show InChI InChI=1S/C24H40N6O2/c1-2-3-12-25-24-26-15-21(22(29-24)27-18-6-8-20(31)9-7-18)23(32)28-19-10-13-30(14-11-19)16-17-4-5-17/h15,17-20,31H,2-14,16H2,1H3,(H,28,32)(H2,25,26,27,29)/t18-,20- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Mer
(Homo sapiens (Human)) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Tyrosine-protein kinase Mer
(Homo sapiens (Human)) | BDBM50602485
(CHEMBL5171919)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM308131
(US9649309, Compound UNC2876A)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.25,wD:27.29,(-10.11,-3.85,;-8.77,-3.08,;-7.44,-3.85,;-6.1,-3.08,;-4.77,-3.85,;-3.44,-3.08,;-2.1,-3.85,;-.77,-3.08,;-.77,-1.54,;.56,-.77,;.56,.77,;1.9,-1.54,;3.23,-.77,;4.56,-1.54,;5.9,-.77,;5.9,.77,;7.23,1.54,;8.57,.77,;9.34,-.56,;10.11,.77,;4.56,1.54,;3.23,.77,;-2.1,-.77,;-2.1,.77,;-3.44,1.54,;-4.77,.77,;-6.1,1.54,;-6.1,3.08,;-7.44,3.85,;-4.77,3.85,;-3.44,3.08,;-3.44,-1.54,)| Show InChI InChI=1S/C24H40N6O2/c1-2-3-12-25-24-26-15-21(22(29-24)27-18-6-8-20(31)9-7-18)23(32)28-19-10-13-30(14-11-19)16-17-4-5-17/h15,17-20,31H,2-14,16H2,1H3,(H,28,32)(H2,25,26,27,29)/t18-,20- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50602485
(CHEMBL5171919)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM308131
(US9649309, Compound UNC2876A)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.25,wD:27.29,(-10.11,-3.85,;-8.77,-3.08,;-7.44,-3.85,;-6.1,-3.08,;-4.77,-3.85,;-3.44,-3.08,;-2.1,-3.85,;-.77,-3.08,;-.77,-1.54,;.56,-.77,;.56,.77,;1.9,-1.54,;3.23,-.77,;4.56,-1.54,;5.9,-.77,;5.9,.77,;7.23,1.54,;8.57,.77,;9.34,-.56,;10.11,.77,;4.56,1.54,;3.23,.77,;-2.1,-.77,;-2.1,.77,;-3.44,1.54,;-4.77,.77,;-6.1,1.54,;-6.1,3.08,;-7.44,3.85,;-4.77,3.85,;-3.44,3.08,;-3.44,-1.54,)| Show InChI InChI=1S/C24H40N6O2/c1-2-3-12-25-24-26-15-21(22(29-24)27-18-6-8-20(31)9-7-18)23(32)28-19-10-13-30(14-11-19)16-17-4-5-17/h15,17-20,31H,2-14,16H2,1H3,(H,28,32)(H2,25,26,27,29)/t18-,20- | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50602485
(CHEMBL5171919)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM308131
(US9649309, Compound UNC2876A)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.25,wD:27.29,(-10.11,-3.85,;-8.77,-3.08,;-7.44,-3.85,;-6.1,-3.08,;-4.77,-3.85,;-3.44,-3.08,;-2.1,-3.85,;-.77,-3.08,;-.77,-1.54,;.56,-.77,;.56,.77,;1.9,-1.54,;3.23,-.77,;4.56,-1.54,;5.9,-.77,;5.9,.77,;7.23,1.54,;8.57,.77,;9.34,-.56,;10.11,.77,;4.56,1.54,;3.23,.77,;-2.1,-.77,;-2.1,.77,;-3.44,1.54,;-4.77,.77,;-6.1,1.54,;-6.1,3.08,;-7.44,3.85,;-4.77,3.85,;-3.44,3.08,;-3.44,-1.54,)| Show InChI InChI=1S/C24H40N6O2/c1-2-3-12-25-24-26-15-21(22(29-24)27-18-6-8-20(31)9-7-18)23(32)28-19-10-13-30(14-11-19)16-17-4-5-17/h15,17-20,31H,2-14,16H2,1H3,(H,28,32)(H2,25,26,27,29)/t18-,20- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50602485
(CHEMBL5171919)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Mer
(Mus musculus) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Mer
(Mus musculus) | BDBM50602486
(CHEMBL5196154)Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113822
BindingDB Entry DOI: 10.7270/Q2TX3KFC |
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Ligand-Target Pair | |
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