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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase receptor UFO | ||
| Ligand | BDBM50602486 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2241011 (CHEMBL5155221) | ||
| IC50 | 170±n/a nM | ||
| Citation |  Wong, SW; Vivash, L; Mudududdla, R; Nguyen, N; Hermans, SJ; Shackleford, DM; Field, J; Xue, L; Aprico, A; Hancock, NC; Haskali, M; Stashko, MA; Frye, SV; Wang, X; Binder, MD; Ackermann, U; Parker, MW; Kilpatrick, TJ; Baell, JB Development of [ Eur J Med Chem226:0 (2021) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase receptor UFO | |||
| Name: | Tyrosine-protein kinase receptor UFO | ||
| Synonyms: | AXL | AXL oncogene | TEL/AXL | Tyrosine-protein kinase receptor UFO (AXL) | UFO | UFO_HUMAN | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 98316.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P30530 | ||
| Residue: | 894 | ||
| Sequence: |
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| BDBM50602486 | |||
| n/a | |||
| Name | BDBM50602486 | ||
| Synonyms: | CHEMBL5196154 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H39FN6O2 | ||
| Mol. Mass. | 450.5932 | ||
| SMILES | CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| | ||
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