Found 124 hits with Last Name = 'may-dracka' and Initial = 'tl' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HGK using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548192
(CHEMBL4749141) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548194
(CHEMBL4762312)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2cc(oc12)-c1c(Cl)ccc(F)c1Cl | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human KHS using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HPK1 using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Hexokinase-4
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548196
(CHEMBL4753188)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2ccc(nc12)-c1cccc(F)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548195
(CHEMBL4782885)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2cc(oc12)-c1cccc(F)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586324
(CHEMBL5085284)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)NC[C@H]2c1cccc(F)c1)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50510309
(CHEMBL4568440)Show SMILES CCC(Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C22H24Cl2FN5O/c1-2-18(20-16(23)3-4-17(25)21(20)24)31-19-9-13(10-28-22(19)26)14-11-29-30(12-14)15-5-7-27-8-6-15/h3-4,9-12,15,18,27H,2,5-8H2,1H3,(H2,26,28) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50510309
(CHEMBL4568440)Show SMILES CCC(Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C22H24Cl2FN5O/c1-2-18(20-16(23)3-4-17(25)21(20)24)31-19-9-13(10-28-22(19)26)14-11-29-30(12-14)15-5-7-27-8-6-15/h3-4,9-12,15,18,27H,2,5-8H2,1H3,(H2,26,28) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548222
(CHEMBL4790577)Show SMILES Nc1ncc(cc1NCc1c(Cl)ccc(F)c1Cl)-c1cnn(c1)C1CCNCC1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548211
(CHEMBL4788727) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586314
(CHEMBL5078848)Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccccc2[nH]c1=O)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548193
(CHEMBL4785602) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50510315
(CHEMBL518323)Show SMILES Nc1ncc(cc1OCc1c(Cl)ccc(F)c1Cl)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20Cl2FN5O/c21-16-1-2-17(23)19(22)15(16)11-29-18-7-12(8-26-20(18)24)13-9-27-28(10-13)14-3-5-25-6-4-14/h1-2,7-10,14,25H,3-6,11H2,(H2,24,26) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586336
(CHEMBL5092677)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1C[C@H](C)N[C@H](C)C1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586327
(CHEMBL5078394)Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccccc2[nH]c1=O)n1ccccc1=O |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586337
(CHEMBL5085809)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1C[C@@H](C)N[C@H](C)C1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM154517
(ML299 (5))Show SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C23H26BrFN4O2/c1-16(27-21(30)17-5-7-18(24)8-6-17)14-28-11-9-23(10-12-28)22(31)26-15-29(23)20-4-2-3-19(25)13-20/h2-8,13,16H,9-12,14-15H2,1H3,(H,26,31)(H,27,30)/t16-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50306682
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D2
(Homo sapiens (Human)) | BDBM50586324
(CHEMBL5085284)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)NC[C@H]2c1cccc(F)c1)NC(=O)c1ccc(F)cc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitation |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586320
(CHEMBL5092708)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)Nc1ccccc21)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D2
(Homo sapiens (Human)) | BDBM154517
(ML299 (5))Show SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C23H26BrFN4O2/c1-16(27-21(30)17-5-7-18(24)8-6-17)14-28-11-9-23(10-12-28)22(31)26-15-29(23)20-4-2-3-19(25)13-20/h2-8,13,16H,9-12,14-15H2,1H3,(H,26,31)(H,27,30)/t16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitation |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586334
(CHEMBL5088048)Show SMILES CC[C@H]1CN(CCN1)C(=O)[C@H](C)N1CCC(CC1)n1c2ccccc2[nH]c1=O |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586321
(CHEMBL5083605)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)Nc1cc(F)ccc21)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548215
(CHEMBL4757394) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586331
(CHEMBL5086717)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1CCN[C@@H](C)C1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548216
(CHEMBL4790293) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548197
(CHEMBL4761177) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548212
(CHEMBL4742776) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548191
(CHEMBL4793665)Show SMILES CCN1CCC(CC1)c1ncc(s1)-c1cnc(N)c(OCc2ccncc2)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) transfected in human 293T cells co-transfected with GFP-fused PKCtheta assessed as reduction in PKCtheta phosphory... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548228
(CHEMBL4755070) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586329
(CHEMBL5074314)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1C[C@@H](C)c2ccccc2C1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548200
(CHEMBL4757177)Show SMILES C[C@@H](Oc1nc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586322
(CHEMBL5092706)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)Nc1ccncc21)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586326
(CHEMBL5075520) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548225
(CHEMBL4782953) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586325
(CHEMBL5076666)Show SMILES CN(CCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)C(C)=O | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586335
(CHEMBL5080858)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1CCNC[C@H]1C |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548229
(CHEMBL4744805)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2ccc(cc12)-c1cccc(F)c1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586328
(CHEMBL5086297)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1CCC(F)(F)C1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548218
(CHEMBL4778070) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548202
(CHEMBL4751159)Show SMILES Nc1ncc(cc1OCc1ccccc1C(F)(F)F)-c1cnn(c1)C1CCNCC1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548223
(CHEMBL4780336) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548201
(CHEMBL4757014) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human)) | BDBM50548227
(CHEMBL4782872)Show SMILES Nc1ncc(cc1C(=O)Nc1ccccc1)-c1cnn(c1)C1CCNCC1 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of GLK (unknown origin) by alphascreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2018.03.032 BindingDB Entry DOI: 10.7270/Q2X3522N |
More data for this Ligand-Target Pair | |
Phospholipase D1
(Homo sapiens (Human)) | BDBM50586323
(CHEMBL5080277)Show SMILES C[C@@H](CN1CCC2(CC1)OC(=O)Nc1cccnc21)NC(=O)c1ccc(F)cc1 |r| | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD1 (unknown origin) expressed in human HEK cells by immunoprecipitation assay |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |
Phospholipase D2
(Homo sapiens (Human)) | BDBM50586336
(CHEMBL5092677)Show SMILES C[C@H](N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N1C[C@H](C)N[C@H](C)C1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitation |
Bioorg Med Chem Lett 14: 5877-80 (2004)
Article DOI: 10.1021/acsmedchemlett.1c00682 BindingDB Entry DOI: 10.7270/Q27H1PGW |
More data for this Ligand-Target Pair | |