Compile Data Set for Download or QSAR

Found 2231 hits with Last Name = 'bobinski' and Initial = 'tp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578799 (4-(aminomethyl)-6-(4-benzyl-4H-1,2,4-triazol-3- yl...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1nncn1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578810 (4-(aminomethyl)-6-(1-methyl-3-(trifluoromethyl)-1H...) Show SMILES Cn1nc(cc1-c1ccc2c(c1)c(CN)n[nH]c2=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578828 (4-(aminomethyl)-6-(1-methyl-1H-pyrrolo[2,3-b]pyrid...) Show SMILES Cn1cc(-c2ccc3c(c2)c(CN)n[nH]c3=O)c2cccnc12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578954 (US11479551, Example 13-1 | US11479551, Example 6-2...) Show SMILES Brc1ccc2c(CN3C(=O)c4ccccc4C3=O)n[nH]c(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578954 (US11479551, Example 13-1 | US11479551, Example 6-2...) Show SMILES Brc1ccc2c(CN3C(=O)c4ccccc4C3=O)n[nH]c(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578799 (4-(aminomethyl)-6-(4-benzyl-4H-1,2,4-triazol-3- yl...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1nncn1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578810 (4-(aminomethyl)-6-(1-methyl-3-(trifluoromethyl)-1H...) Show SMILES Cn1nc(cc1-c1ccc2c(c1)c(CN)n[nH]c2=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578828 (4-(aminomethyl)-6-(1-methyl-1H-pyrrolo[2,3-b]pyrid...) Show SMILES Cn1cc(-c2ccc3c(c2)c(CN)n[nH]c3=O)c2cccnc12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM378893 (5,8-dichloro-2-((7-methyl-5-oxo-5,6-dihydro-1H-pyr...) Show SMILES Cc1[nH]c(=O)c(CN2CCc3c(Cl)cc(N4CC5(C4)CCOCC5)c(Cl)c3C2=O)c2CCNc12 Show InChI InChI=1S/C25H28Cl2N4O3/c1-14-22-15(2-6-28-22)17(23(32)29-14)11-30-7-3-16-18(26)10-19(21(27)20(16)24(30)33)31-12-25(13-31)4-8-34-9-5-25/h10,28H,2-9,11-13H2,1H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description Ten-point dose-response curves for a subset of compounds shown in Table 1 were determined using a Transcreener® EPIGEN Methyltransferase HTS assay us...				J Med Chem 51: 4150-69 (2008) BindingDB Entry DOI: 10.7270/Q2WM1GRX
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578895 (4-(aminomethyl)-6-(5-(2- methoxyphenoxy)pyridin-3-...) Show SMILES COc1ccccc1Oc1cncc(c1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578831 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1cccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c1C#N |(-6.5,-1.85,;-5.41,-2.93,;-3.92,-2.54,;-2.83,-3.62,;-1.34,-3.23,;-.95,-1.74,;-2.03,-.65,;-1.64,.84,;-.17,1.31,;-.17,2.85,;-1.64,3.33,;-2.54,2.08,;-4.08,2.08,;1.16,.54,;1.16,-1,;2.5,-1.77,;3.83,-1,;3.83,.54,;2.5,1.31,;5.16,1.31,;5.16,2.85,;6.5,3.62,;6.5,.54,;6.5,-1,;5.16,-1.77,;5.16,-3.31,;-3.52,-1.05,;-4.61,.04,;-5.7,1.13,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578823 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1cc(Cl)ccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.43,;-2.94,2.43,;-2.03,3.68,;-.57,3.2,;-.57,1.66,;-2.03,1.18,;-2.43,-.3,;-1.34,-1.39,;-1.74,-2.88,;-.65,-3.97,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578831 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1cccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c1C#N |(-6.5,-1.85,;-5.41,-2.93,;-3.92,-2.54,;-2.83,-3.62,;-1.34,-3.23,;-.95,-1.74,;-2.03,-.65,;-1.64,.84,;-.17,1.31,;-.17,2.85,;-1.64,3.33,;-2.54,2.08,;-4.08,2.08,;1.16,.54,;1.16,-1,;2.5,-1.77,;3.83,-1,;3.83,.54,;2.5,1.31,;5.16,1.31,;5.16,2.85,;6.5,3.62,;6.5,.54,;6.5,-1,;5.16,-1.77,;5.16,-3.31,;-3.52,-1.05,;-4.61,.04,;-5.7,1.13,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578829 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cc1ccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(c1)C#N |(-3.63,-4.37,;-3.23,-2.88,;-1.74,-2.48,;-1.34,-.99,;-2.43,.09,;-2.03,1.58,;-.57,2.06,;-.57,3.6,;-2.03,4.07,;-2.94,2.83,;-4.48,2.83,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,;-3.92,-.3,;-4.32,-1.79,;-5.01,.78,;-6.1,1.87,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578825 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(.83,-3.57,;-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578823 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1cc(Cl)ccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.43,;-2.94,2.43,;-2.03,3.68,;-.57,3.2,;-.57,1.66,;-2.03,1.18,;-2.43,-.3,;-1.34,-1.39,;-1.74,-2.88,;-.65,-3.97,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578821 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccc(Cl)cc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.83,;-2.94,2.83,;-2.03,4.07,;-.57,3.6,;-.57,2.06,;-2.03,1.58,;-2.43,.09,;-1.34,-.99,;-1.74,-2.48,;-3.23,-2.88,;-3.63,-4.37,;-4.32,-1.79,;-3.92,-.3,;-5.01,.78,;-6.1,1.87,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578819 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.08,;-2.94,2.08,;-2.03,3.33,;-.57,2.85,;-.57,1.31,;-2.03,.84,;-2.43,-.65,;-1.34,-1.74,;-1.74,-3.23,;-3.23,-3.62,;-4.32,-2.54,;-3.92,-1.05,;-5.01,.04,;-6.1,1.13,;.76,.54,;.76,-1,;2.1,-1.77,;3.43,-1,;3.43,.54,;2.1,1.31,;4.76,1.31,;4.76,2.85,;3.43,3.62,;6.1,.54,;6.1,-1,;4.76,-1.77,;4.76,-3.31,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578821 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccc(Cl)cc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.83,;-2.94,2.83,;-2.03,4.07,;-.57,3.6,;-.57,2.06,;-2.03,1.58,;-2.43,.09,;-1.34,-.99,;-1.74,-2.48,;-3.23,-2.88,;-3.63,-4.37,;-4.32,-1.79,;-3.92,-.3,;-5.01,.78,;-6.1,1.87,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578825 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(.83,-3.57,;-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578829 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cc1ccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(c1)C#N |(-3.63,-4.37,;-3.23,-2.88,;-1.74,-2.48,;-1.34,-.99,;-2.43,.09,;-2.03,1.58,;-.57,2.06,;-.57,3.6,;-2.03,4.07,;-2.94,2.83,;-4.48,2.83,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,;-3.92,-.3,;-4.32,-1.79,;-5.01,.78,;-6.1,1.87,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578895 (4-(aminomethyl)-6-(5-(2- methoxyphenoxy)pyridin-3-...) Show SMILES COc1ccccc1Oc1cncc(c1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578819 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.08,;-2.94,2.08,;-2.03,3.33,;-.57,2.85,;-.57,1.31,;-2.03,.84,;-2.43,-.65,;-1.34,-1.74,;-1.74,-3.23,;-3.23,-3.62,;-4.32,-2.54,;-3.92,-1.05,;-5.01,.04,;-6.1,1.13,;.76,.54,;.76,-1,;2.1,-1.77,;3.43,-1,;3.43,.54,;2.1,1.31,;4.76,1.31,;4.76,2.85,;3.43,3.62,;6.1,.54,;6.1,-1,;4.76,-1.77,;4.76,-3.31,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578885 (4-(aminomethyl)-6-(5-(2,4- dimethylphenoxy)pyridin...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(C)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578922 (4-(aminomethyl)-6-(3-(methoxymethyl)-1H- pyrrolo[2...) Show SMILES COCc1c[nH]c2ncc(cc12)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578885 (4-(aminomethyl)-6-(5-(2,4- dimethylphenoxy)pyridin...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(C)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578922 (4-(aminomethyl)-6-(3-(methoxymethyl)-1H- pyrrolo[2...) Show SMILES COCc1c[nH]c2ncc(cc12)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578889 (4-(aminomethyl)-6-(5-(3-chloro-2- methylphenoxy)py...) Show SMILES Cc1c(Cl)cccc1Oc1cncc(c1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578889 (4-(aminomethyl)-6-(5-(3-chloro-2- methylphenoxy)py...) Show SMILES Cc1c(Cl)cccc1Oc1cncc(c1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM378912 (5,8-dichloro-7-[methoxy(oxetan-3-yl)methyl]-2-[(7-...) Show SMILES COC(C1COC1)c1cc(Cl)c2CCN(Cc3c4ccn(C)c4c(C)[nH]c3=O)C(=O)c2c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description Ten-point dose-response curves for a subset of compounds shown in Table 1 were determined using a Transcreener® EPIGEN Methyltransferase HTS assay us...				J Med Chem 51: 4150-69 (2008) BindingDB Entry DOI: 10.7270/Q2WM1GRX
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578893 (4-(aminomethyl)-6-(5-(4- methoxyphenoxy)pyridin-3-...) Show SMILES COc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578893 (4-(aminomethyl)-6-(5-(4- methoxyphenoxy)pyridin-3-...) Show SMILES COc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578887 (4-(aminomethyl)-6-(5-(3-chloro-4- methylphenoxy)py...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)cc1Cl Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578902 (4-(aminomethyl)-6-(6- cyclopropoxyimidazo[1,2-a]py...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cnc2ccc(OC3CC3)cn12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578887 (4-(aminomethyl)-6-(5-(3-chloro-4- methylphenoxy)py...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)cc1Cl Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578902 (4-(aminomethyl)-6-(6- cyclopropoxyimidazo[1,2-a]py...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cnc2ccc(OC3CC3)cn12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578942 (4-(aminomethyl)-6-(5-(phenylthio)pyridin-3- yl)pht...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cncc(Sc2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578942 (4-(aminomethyl)-6-(5-(phenylthio)pyridin-3- yl)pht...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cncc(Sc2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578891 (4-(aminomethyl)-6-(5-(3-chloro-2,4- dimethylphenox...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(C)c1Cl Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578891 (4-(aminomethyl)-6-(5-(3-chloro-2,4- dimethylphenox...) Show SMILES Cc1ccc(Oc2cncc(c2)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(C)c1Cl Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578892 (4-(aminomethyl)-6-(1-methyl-5-phenyl-1H- pyrazol-4...) Show SMILES Cn1ncc(c1-c1ccccc1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578892 (4-(aminomethyl)-6-(1-methyl-5-phenyl-1H- pyrazol-4...) Show SMILES Cn1ncc(c1-c1ccccc1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578937 (4-(aminomethyl)-6-(1-methyl-5-(p-tolyl)-1H- pyrazo...) Show SMILES Cc1ccc(cc1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578937 (4-(aminomethyl)-6-(1-methyl-5-(p-tolyl)-1H- pyrazo...) Show SMILES Cc1ccc(cc1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578906 (4-(aminomethyl)-6-(6-phenylimidazo[1,2- a]pyridin-...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cnc2ccc(cn12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578906 (4-(aminomethyl)-6-(6-phenylimidazo[1,2- a]pyridin-...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cnc2ccc(cn12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578827 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578827 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578948 (4-(aminomethyl)-6-(5-((2- chlorophenyl)thio)pyridi...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cncc(Sc2ccccc2Cl)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578948 (4-(aminomethyl)-6-(5-((2- chlorophenyl)thio)pyridi...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cncc(Sc2ccccc2Cl)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair

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