Compile Data Set for Download or QSAR

Found 65 hits with Last Name = 'hungerford' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM14712 ((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...) Show SMILES CC(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,10H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066577 (5-Methyl-3-(4-trifluoromethoxy-phenylamino)-1H-pyr...) Show SMILES Cc1n[nH]c(Nc2ccc(OC(F)(F)F)cc2)c1C#N Show InChI InChI=1S/C12H9F3N4O/c1-7-10(6-16)11(19-18-7)17-8-2-4-9(5-3-8)20-12(13,14)15/h2-5H,1H3,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071393 (5-Ethyl-isoxazole-4-carbothioic acid (4-trifluorom...) Show SMILES CCc1oncc1C(=S)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C13H11F3N2O2S/c1-2-11-10(7-17-20-11)12(21)18-8-3-5-9(6-4-8)19-13(14,15)16/h3-7H,2H2,1H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071387 (5-Cyclopropyl-isoxazole-4-carbothioic acid (4-trif...) Show SMILES FC(F)(F)Oc1ccc(NC(=S)c2cnoc2C2CC2)cc1 Show InChI InChI=1S/C14H11F3N2O2S/c15-14(16,17)20-10-5-3-9(4-6-10)19-13(22)11-7-18-21-12(11)8-1-2-8/h3-8H,1-2H2,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071392 ((E)-2-Cyano-3-hydroxy-but-2-enethioic acid (4-trif...) Show SMILES CC(=O)C(C#N)C(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H9F3N2OS/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,10H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066601 (5-Methyl-3-(4-trifluoromethyl-phenylamino)-1H-pyra...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1C#N Show InChI InChI=1S/C12H9F3N4/c1-7-10(6-16)11(19-18-7)17-9-4-2-8(3-5-9)12(13,14)15/h2-5H,1H3,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066591 (CHEMBL118894 | [5-Methyl-3-(4-trifluoromethyl-phen...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1CO Show InChI InChI=1S/C12H12F3N3O/c1-7-10(6-19)11(18-17-7)16-9-4-2-8(3-5-9)12(13,14)15/h2-5,19H,6H2,1H3,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071403 (5-Ethyl-isoxazole-4-carbothioic acid (4-trifluorom...) Show SMILES CCc1oncc1C(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N2OS/c1-2-11-10(7-17-19-11)12(20)18-9-5-3-8(4-6-9)13(14,15)16/h3-7H,2H2,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066588 (3-(4-Cyano-phenylamino)-5-methyl-1H-pyrazole-4-car...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C#N)c1C#N Show InChI InChI=1S/C12H9N5/c1-8-11(7-14)12(17-16-8)15-10-4-2-9(6-13)3-5-10/h2-5H,1H3,(H2,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071394 (5-Cyclopropyl-isoxazole-4-carbothioic acid (4-trif...) Show SMILES FC(F)(F)c1ccc(NC(=S)c2cnoc2C2CC2)cc1 Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-5-10(6-4-9)19-13(21)11-7-18-20-12(11)8-1-2-8/h3-8H,1-2H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066590 (3-(4-tert-Butyl-phenylamino)-5-methyl-1H-pyrazole-...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C(C)(C)C)c1C#N Show InChI InChI=1S/C15H18N4/c1-10-13(9-16)14(19-18-10)17-12-7-5-11(6-8-12)15(2,3)4/h5-8H,1-4H3,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066576 (5-Isopropyl-3-(4-trifluoromethyl-phenylamino)-1H-p...) Show SMILES CC(C)c1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1C#N Show InChI InChI=1S/C14H13F3N4/c1-8(2)12-11(7-18)13(21-20-12)19-10-5-3-9(4-6-10)14(15,16)17/h3-6,8H,1-2H3,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066594 ((4,5,6,7-Tetrahydro-1H-indazol-3-yl)-(4-trifluorom...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc3CCCCc23)cc1 Show InChI InChI=1S/C14H14F3N3/c15-14(16,17)9-5-7-10(8-6-9)18-13-11-3-1-2-4-12(11)19-20-13/h5-8H,1-4H2,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066580 (3-(4-Trifluoromethyl-phenylamino)-1,5,6,7-tetrahyd...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc3CCCC(=O)c23)cc1 Show InChI InChI=1S/C14H12F3N3O/c15-14(16,17)8-4-6-9(7-5-8)18-13-12-10(19-20-13)2-1-3-11(12)21/h4-7H,1-3H2,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071396 (5-Methyl-isoxazole-4-carbothioic acid (4-trifluoro...) Show SMILES Cc1oncc1C(=S)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C12H9F3N2O2S/c1-7-10(6-16-19-7)11(20)17-8-2-4-9(5-3-8)18-12(13,14)15/h2-6H,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066585 (5-Methyl-3-(4-nitro-phenylamino)-1H-pyrazole-4-car...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)[N+]([O-])=O)c1C#N Show InChI InChI=1S/C11H9N5O2/c1-7-10(6-12)11(15-14-7)13-8-2-4-9(5-3-8)16(17)18/h2-5H,1H3,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071398 (5-Cyclopropyl-isoxazole-4-carbothioic acid (4-cyan...) Show SMILES S=C(Nc1ccc(cc1)C#N)c1cnoc1C1CC1 Show InChI InChI=1S/C14H11N3OS/c15-7-9-1-5-11(6-2-9)17-14(19)12-8-16-18-13(12)10-3-4-10/h1-2,5-6,8,10H,3-4H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50054601 (5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...) Show SMILES Cc1oncc1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071401 (5-Ethyl-isoxazole-4-carbothioic acid (4-cyano-phen...) Show SMILES CCc1oncc1C(=S)Nc1ccc(cc1)C#N Show InChI InChI=1S/C13H11N3OS/c1-2-12-11(8-15-17-12)13(18)16-10-5-3-9(7-14)4-6-10/h3-6,8H,2H2,1H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066609 (5-Methyl-3-p-tolylamino-1H-pyrazole-4-carbonitrile...) Show SMILES Cc1n[nH]c(Nc2ccc(C)cc2)c1C#N Show InChI InChI=1S/C12H12N4/c1-8-3-5-10(6-4-8)14-12-11(7-13)9(2)15-16-12/h3-6H,1-2H3,(H2,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50054601 (5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...) Show SMILES Cc1oncc1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066598 ((5-Methyl-1H-pyrazol-3-yl)-(4-trifluoromethyl-phen...) Show SMILES Cc1cc(Nc2ccc(cc2)C(F)(F)F)[nH]n1 Show InChI InChI=1S/C11H10F3N3/c1-7-6-10(17-16-7)15-9-4-2-8(3-5-9)11(12,13)14/h2-6H,1H3,(H2,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066603 (3-(4-Fluoro-phenylamino)-5-methyl-1H-pyrazole-4-ca...) Show SMILES Cc1n[nH]c(Nc2ccc(F)cc2)c1C#N Show InChI InChI=1S/C11H9FN4/c1-7-10(6-13)11(16-15-7)14-9-4-2-8(12)3-5-9/h2-5H,1H3,(H2,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066586 (5-Methyl-3-(2,4,6-trifluoro-phenylamino)-1H-pyrazo...) Show SMILES Cc1n[nH]c(Nc2c(F)cc(F)cc2F)c1C#N Show InChI InChI=1S/C11H7F3N4/c1-5-7(4-15)11(18-17-5)16-10-8(13)2-6(12)3-9(10)14/h2-3H,1H3,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066599 ((4,5-Dimethyl-1H-pyrazol-3-yl)-(4-trifluoromethyl-...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1C Show InChI InChI=1S/C12H12F3N3/c1-7-8(2)17-18-11(7)16-10-5-3-9(4-6-10)12(13,14)15/h3-6H,1-2H3,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071400 (5-Methyl-isoxazole-4-carbothioic acid (4-cyano-phe...) Show SMILES Cc1oncc1C(=S)Nc1ccc(cc1)C#N Show InChI InChI=1S/C12H9N3OS/c1-8-11(7-14-16-8)12(17)15-10-4-2-9(6-13)3-5-10/h2-5,7H,1H3,(H,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071389 (5-Ethyl-isoxazole-4-carbothioic acid (4-dimethylam...) Show SMILES CCc1oncc1C(=S)Nc1ccc(cc1)N(C)C Show InChI InChI=1S/C14H17N3OS/c1-4-13-12(9-15-18-13)14(19)16-10-5-7-11(8-6-10)17(2)3/h5-9H,4H2,1-3H3,(H,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071402 (5-Cyclohexyl-isoxazole-4-carbothioic acid (4-cyano...) Show SMILES S=C(Nc1ccc(cc1)C#N)c1cnoc1C1CCCCC1 Show InChI InChI=1S/C17H17N3OS/c18-10-12-6-8-14(9-7-12)20-17(22)15-11-19-21-16(15)13-4-2-1-3-5-13/h6-9,11,13H,1-5H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071404 (5-tert-Butyl-isoxazole-4-carbothioic acid (4-trifl...) Show SMILES CC(C)(C)c1oncc1C(=S)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H15F3N2O2S/c1-14(2,3)12-11(8-19-22-12)13(23)20-9-4-6-10(7-5-9)21-15(16,17)18/h4-8H,1-3H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071407 (5-Cyclopropyl-isoxazole-4-carbothioic acid (4-dime...) Show SMILES CN(C)c1ccc(NC(=S)c2cnoc2C2CC2)cc1 Show InChI InChI=1S/C15H17N3OS/c1-18(2)12-7-5-11(6-8-12)17-15(20)13-9-16-19-14(13)10-3-4-10/h5-10H,3-4H2,1-2H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071395 (5-Methyl-isoxazole-4-carbothioic acid (4-trifluoro...) Show SMILES Cc1oncc1C(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H9F3N2OS/c1-7-10(6-16-18-7)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071405 (5-Methyl-isoxazole-4-carbothioic acid (4-dimethyla...) Show SMILES CN(C)c1ccc(NC(=S)c2cnoc2C)cc1 Show InChI InChI=1S/C13H15N3OS/c1-9-12(8-14-17-9)13(18)15-10-4-6-11(7-5-10)16(2)3/h4-8H,1-3H3,(H,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071408 (5-Hexyl-isoxazole-4-carbothioic acid (4-trifluorom...) Show SMILES CCCCCCc1oncc1C(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H19F3N2OS/c1-2-3-4-5-6-15-14(11-21-23-15)16(24)22-13-9-7-12(8-10-13)17(18,19)20/h7-11H,2-6H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071409 (5-tert-Butyl-isoxazole-4-carbothioic acid (4-dimet...) Show SMILES CN(C)c1ccc(NC(=S)c2cnoc2C(C)(C)C)cc1 Show InChI InChI=1S/C16H21N3OS/c1-16(2,3)14-13(10-17-20-14)15(21)18-11-6-8-12(9-7-11)19(4)5/h6-10H,1-5H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50071410 (5-Hexyl-isoxazole-4-carbothioic acid (4-dimethylam...) Show SMILES CCCCCCc1oncc1C(=S)Nc1ccc(cc1)N(C)C Show InChI InChI=1S/C18H25N3OS/c1-4-5-6-7-8-17-16(13-19-22-17)18(23)20-14-9-11-15(12-10-14)21(2)3/h9-13H,4-8H2,1-3H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)				Bioorg Med Chem Lett 8: 2203-8 (1999) BindingDB Entry DOI: 10.7270/Q2QN65X4
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066578 (5-Pyridin-4-yl-3-(4-trifluoromethyl-phenylamino)-1...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc(c2C#N)-c2ccncc2)cc1 Show InChI InChI=1S/C16H10F3N5/c17-16(18,19)11-1-3-12(4-2-11)22-15-13(9-20)14(23-24-15)10-5-7-21-8-6-10/h1-8H,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50022815 ((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...) Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |r| Show InChI InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066583 (CHEMBL432427 | [4-(1-Hydrazono-ethyl)-5-methyl-1H-...) Show SMILES CC(N=N)c1c(C)n[nH]c1Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H14F3N5/c1-7(19-17)11-8(2)20-21-12(11)18-10-5-3-9(4-6-10)13(14,15)16/h3-7,17H,1-2H3,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066587 ((5-Methyl-4-phenyl-1H-pyrazol-3-yl)-(4-trifluorome...) Show SMILES Cc1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1-c1ccccc1 Show InChI InChI=1S/C17H14F3N3/c1-11-15(12-5-3-2-4-6-12)16(23-22-11)21-14-9-7-13(8-10-14)17(18,19)20/h2-10H,1H3,(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066592 (5-Pyridin-3-yl-3-(4-trifluoromethyl-phenylamino)-1...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc(c2C#N)-c2cccnc2)cc1 Show InChI InChI=1S/C16H10F3N5/c17-16(18,19)11-3-5-12(6-4-11)22-15-13(8-20)14(23-24-15)10-2-1-7-21-9-10/h1-7,9H,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066584 (3-(4-Amino-phenylamino)-5-methyl-1H-pyrazole-4-car...) Show SMILES Cc1n[nH]c(Nc2ccc(N)cc2)c1C#N Show InChI InChI=1S/C11H11N5/c1-7-10(6-12)11(16-15-7)14-9-4-2-8(13)3-5-9/h2-5H,13H2,1H3,(H2,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066600 (5-Methyl-3-(3-trifluoromethyl-phenylamino)-1H-pyra...) Show SMILES Cc1n[nH]c(Nc2cccc(c2)C(F)(F)F)c1C#N Show InChI InChI=1S/C12H9F3N4/c1-7-10(6-16)11(19-18-7)17-9-4-2-3-8(5-9)12(13,14)15/h2-5H,1H3,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066596 (5-tert-Butyl-3-(4-trifluoromethyl-phenylamino)-1H-...) Show SMILES CC(C)(C)c1n[nH]c(Nc2ccc(cc2)C(F)(F)F)c1C#N Show InChI InChI=1S/C15H15F3N4/c1-14(2,3)12-11(8-19)13(22-21-12)20-10-6-4-9(5-7-10)15(16,17)18/h4-7H,1-3H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066582 (5-Cyclopentyl-3-(4-trifluoromethyl-phenylamino)-1H...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc(C3CCCC3)c2C#N)cc1 Show InChI InChI=1S/C16H15F3N4/c17-16(18,19)11-5-7-12(8-6-11)21-15-13(9-20)14(22-23-15)10-3-1-2-4-10/h5-8,10H,1-4H2,(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066593 (5-Methyl-3-(2-trifluoromethyl-phenylamino)-1H-pyra...) Show SMILES Cc1n[nH]c(Nc2ccccc2C(F)(F)F)c1C#N Show InChI InChI=1S/C12H9F3N4/c1-7-8(6-16)11(19-18-7)17-10-5-3-2-4-9(10)12(13,14)15/h2-5H,1H3,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066589 (5-Hydroxy-3-(4-trifluoromethyl-phenylamino)-1H-pyr...) Show SMILES FC(F)(F)c1ccc(Nc2[nH][nH]c(=O)c2C#N)cc1 Show InChI InChI=1S/C11H7F3N4O/c12-11(13,14)6-1-3-7(4-2-6)16-9-8(5-15)10(19)18-17-9/h1-4H,(H3,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066579 (5-Methyl-3-[methyl-(4-trifluoromethyl-phenyl)-amin...) Show SMILES CN(c1[nH]nc(C)c1C#N)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N4/c1-8-11(7-17)12(19-18-8)20(2)10-5-3-9(4-6-10)13(14,15)16/h3-6H,1-2H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066581 (5-Methyl-3-(4-trifluoromethyl-benzylamino)-1H-pyra...) Show SMILES Cc1n[nH]c(NCc2ccc(cc2)C(F)(F)F)c1C#N Show InChI InChI=1S/C13H11F3N4/c1-8-11(6-17)12(20-19-8)18-7-9-2-4-10(5-3-9)13(14,15)16/h2-5H,7H2,1H3,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066604 (5-Methyl-3-(4-trifluoromethyl-phenylamino)-1H-pyra...) Show SMILES CCOC(=O)c1c(C)n[nH]c1Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H14F3N3O2/c1-3-22-13(21)11-8(2)19-20-12(11)18-10-6-4-9(5-7-10)14(15,16)17/h4-7H,3H2,1-2H3,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50066610 (5-Furan-2-yl-3-(4-trifluoromethyl-phenylamino)-1H-...) Show SMILES FC(F)(F)c1ccc(Nc2[nH]nc(-c3ccco3)c2C#N)cc1 Show InChI InChI=1S/C15H9F3N4O/c16-15(17,18)9-3-5-10(6-4-9)20-14-11(8-19)13(21-22-14)12-2-1-7-23-12/h1-7H,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)				J Med Chem 41: 3530-8 (1998) Article DOI: 10.1021/jm981028c BindingDB Entry DOI: 10.7270/Q2668DW6
					More data for this Ligand-Target Pair

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