Found 81 hits with Last Name = 'selchau' and Initial = 'v' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251448
(4-(((3-((2-(4-benzylphenylamino)-2-oxoethyl)(methy...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O3/c1-30(20-24-9-13-25(14-10-24)28(33)34)17-6-18-31(2)21-27(32)29-26-15-11-23(12-16-26)19-22-7-4-3-5-8-22/h3-5,7-16H,6,17-21H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251386
(4-(2-(methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylami...)Show SMILES CN(CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1)CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H33N3O4/c1-30(20-17-22-9-11-23(12-10-22)28(33)34)18-6-19-31(2)21-27(32)29-24-13-15-26(16-14-24)35-25-7-4-3-5-8-25/h3-5,7-16H,6,17-21H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251420
(2-((3-((4-(1H-tetrazol-5-yl)benzyl)(methyl)amino)p...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)-c1nnn[nH]1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H31N7O2/c1-33(19-21-9-11-22(12-10-21)27-29-31-32-30-27)17-6-18-34(2)20-26(35)28-23-13-15-25(16-14-23)36-24-7-4-3-5-8-24/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,35)(H,29,30,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251473
(4-((methyl(3-(methyl(2-(4-(4-(oxazol-2-yl)phenoxy)...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 Show InChI InChI=1S/C30H32N4O5/c1-33(20-22-4-6-24(7-5-22)30(36)37)17-3-18-34(2)21-28(35)32-25-10-14-27(15-11-25)39-26-12-8-23(9-13-26)29-31-16-19-38-29/h4-16,19H,3,17-18,20-21H2,1-2H3,(H,32,35)(H,36,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251446
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H31N3O4/c1-29(19-21-9-11-22(12-10-21)27(32)33)17-6-18-30(2)20-26(31)28-23-13-15-25(16-14-23)34-24-7-4-3-5-8-24/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251449
(4-(((3-((2-(4-(4-fluorophenoxy)phenylamino)-2-oxoe...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-20-4-6-21(7-5-20)27(33)34)16-3-17-31(2)19-26(32)29-23-10-14-25(15-11-23)35-24-12-8-22(28)9-13-24/h4-15H,3,16-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251828
(2-fluoro-4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyph...)Show SMILES CN(CCCN(C)Cc1ccc(C(O)=O)c(F)c1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-20-9-14-24(27(33)34)25(28)17-20)15-6-16-31(2)19-26(32)29-21-10-12-23(13-11-21)35-22-7-4-3-5-8-22/h3-5,7-14,17H,6,15-16,18-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251587
((R)-4-((2-((methyl(2-oxo-2-(4-phenoxyphenylamino)e...)Show SMILES CN(C[C@H]1CCCN1Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C28H31N3O4/c1-30(19-24-6-5-17-31(24)18-21-9-11-22(12-10-21)28(33)34)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251500
(4-(((2,2-dimethyl-3-(methyl(2-oxo-2-(4-phenoxyphen...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC(C)(C)CN(C)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H35N3O4/c1-29(2,20-31(3)18-22-10-12-23(13-11-22)28(34)35)21-32(4)19-27(33)30-24-14-16-26(17-15-24)36-25-8-6-5-7-9-25/h5-17H,18-21H2,1-4H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251826
(3-fluoro-4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyph...)Show SMILES CN(CCCN(C)Cc1ccc(cc1F)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-21-10-9-20(27(33)34)17-25(21)28)15-6-16-31(2)19-26(32)29-22-11-13-24(14-12-22)35-23-7-4-3-5-8-23/h3-5,7-14,17H,6,15-16,18-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251384
(2-bromo-4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphe...)Show SMILES CN(CCCN(C)Cc1ccc(C(O)=O)c(Br)c1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H30BrN3O4/c1-30(18-20-9-14-24(27(33)34)25(28)17-20)15-6-16-31(2)19-26(32)29-21-10-12-23(13-11-21)35-22-7-4-3-5-8-22/h3-5,7-14,17H,6,15-16,18-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251501
(4-((methyl(2-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29N3O4/c1-28(18-20-8-10-21(11-9-20)26(31)32)16-17-29(2)19-25(30)27-22-12-14-24(15-13-22)33-23-6-4-3-5-7-23/h3-15H,16-19H2,1-2H3,(H,27,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251827
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)Cc1ccc(cc1[N+]([O-])=O)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H30N4O6/c1-29(18-21-10-9-20(27(33)34)17-25(21)31(35)36)15-6-16-30(2)19-26(32)28-22-11-13-24(14-12-22)37-23-7-4-3-5-8-23/h3-5,7-14,17H,6,15-16,18-19H2,1-2H3,(H,28,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251447
(4-(((3-((2-(4-(2-fluorophenoxy)phenylamino)-2-oxoe...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2F)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-20-8-10-21(11-9-20)27(33)34)16-5-17-31(2)19-26(32)29-22-12-14-23(15-13-22)35-25-7-4-3-6-24(25)28/h3-4,6-15H,5,16-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251471
(4-(((3-((2-(4-(4-chlorophenoxy)phenylamino)-2-oxoe...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C27H30ClN3O4/c1-30(18-20-4-6-21(7-5-20)27(33)34)16-3-17-31(2)19-26(32)29-23-10-14-25(15-11-23)35-24-12-8-22(28)9-13-24/h4-15H,3,16-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251588
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H31N3O4/c1-30(18-21-9-11-22(12-10-21)28(33)34)19-24-6-5-17-31(24)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251588
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H31N3O4/c1-30(18-21-9-11-22(12-10-21)28(33)34)19-24-6-5-17-31(24)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251797
(5-(methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino)...)Show SMILES CN(CCCCC(O)=O)CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H33N3O4/c1-26(16-7-6-11-24(29)30)17-8-18-27(2)19-23(28)25-20-12-14-22(15-13-20)31-21-9-4-3-5-10-21/h3-5,9-10,12-15H,6-8,11,16-19H2,1-2H3,(H,25,28)(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251472
(4-(((3-((2-(4-(2-hydroxy-2-phenylethoxy)phenylamin...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(OCC(O)c2ccccc2)cc1 Show InChI InChI=1S/C29H35N3O5/c1-31(19-22-9-11-24(12-10-22)29(35)36)17-6-18-32(2)20-28(34)30-25-13-15-26(16-14-25)37-21-27(33)23-7-4-3-5-8-23/h3-5,7-16,27,33H,6,17-21H2,1-2H3,(H,30,34)(H,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251499
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CCCNCc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29N3O4/c1-29(17-5-16-27-18-20-8-10-21(11-9-20)26(31)32)19-25(30)28-22-12-14-24(15-13-22)33-23-6-3-2-4-7-23/h2-4,6-15,27H,5,16-19H2,1H3,(H,28,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251825
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC1CCC(CC1)C(O)=O |(7.49,-15.66,;7.49,-14.12,;6.16,-13.35,;4.83,-14.12,;3.49,-13.35,;2.16,-14.12,;2.16,-15.66,;.83,-13.35,;-.51,-14.11,;-.51,-15.65,;-1.84,-13.34,;-3.18,-14.11,;-4.52,-13.34,;-5.85,-14.11,;-5.85,-15.66,;-7.18,-16.43,;-8.51,-15.65,;-9.85,-16.43,;-11.18,-15.66,;-11.18,-14.12,;-9.83,-13.35,;-8.51,-14.12,;-4.52,-16.43,;-3.18,-15.66,;8.83,-13.35,;10.16,-14.12,;10.15,-15.66,;11.48,-16.43,;12.81,-15.67,;12.82,-14.13,;11.49,-13.35,;14.15,-16.45,;14.14,-17.99,;15.48,-15.68,)| Show InChI InChI=1S/C27H37N3O4/c1-29(19-21-9-11-22(12-10-21)27(32)33)17-6-18-30(2)20-26(31)28-23-13-15-25(16-14-23)34-24-7-4-3-5-8-24/h3-5,7-8,13-16,21-22H,6,9-12,17-20H2,1-2H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251385
(5-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)Cc1ccc(o1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H29N3O5/c1-27(17-22-13-14-23(33-22)25(30)31)15-6-16-28(2)18-24(29)26-19-9-11-21(12-10-19)32-20-7-4-3-5-8-20/h3-5,7-14H,6,15-18H2,1-2H3,(H,26,29)(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251587
((R)-4-((2-((methyl(2-oxo-2-(4-phenoxyphenylamino)e...)Show SMILES CN(C[C@H]1CCCN1Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C28H31N3O4/c1-30(19-24-6-5-17-31(24)18-21-9-11-22(12-10-21)28(33)34)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34)/t24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251387
(2-(Methyl-{3-[methyl-(4-sulfamoyl-benzyl)-amino]-p...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)S(N)(=O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H32N4O4S/c1-29(19-21-9-15-25(16-10-21)35(27,32)33)17-6-18-30(2)20-26(31)28-22-11-13-24(14-12-22)34-23-7-4-3-5-8-23/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,31)(H2,27,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251522
(4-((5-(2-oxo-2-(4-phenoxyphenylamino)ethyl)-2,5-di...)Show SMILES OC(=O)c1ccc(CN2CC3CC2CN3CC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 |THB:7:8:14.13:11,15:14:11:8.9| Show InChI InChI=1S/C27H27N3O4/c31-26(28-21-10-12-25(13-11-21)34-24-4-2-1-3-5-24)18-30-17-22-14-23(30)16-29(22)15-19-6-8-20(9-7-19)27(32)33/h1-13,22-23H,14-18H2,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251623
(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1 Show InChI InChI=1S/C27H29N3O4/c1-29(23-15-16-30(18-23)17-20-7-9-21(10-8-20)27(32)33)19-26(31)28-22-11-13-25(14-12-22)34-24-5-3-2-4-6-24/h2-14,23H,15-19H2,1H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251399
(4-((4-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)CC1 Show InChI InChI=1S/C28H31N3O4/c1-30(24-15-17-31(18-16-24)19-21-7-9-22(10-8-21)28(33)34)20-27(32)29-23-11-13-26(14-12-23)35-25-5-3-2-4-6-25/h2-14,24H,15-20H2,1H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251473
(4-((methyl(3-(methyl(2-(4-(4-(oxazol-2-yl)phenoxy)...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 Show InChI InChI=1S/C30H32N4O5/c1-33(20-22-4-6-24(7-5-22)30(36)37)17-3-18-34(2)21-28(35)32-25-10-14-27(15-11-25)39-26-12-8-23(9-13-26)29-31-16-19-38-29/h4-16,19H,3,17-18,20-21H2,1-2H3,(H,32,35)(H,36,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251588
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H31N3O4/c1-30(18-21-9-11-22(12-10-21)28(33)34)19-24-6-5-17-31(24)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251555
(4-((methyl((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl...)Show SMILES CN(CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H33N3O4/c1-31(19-22-10-12-23(13-11-22)29(34)35)20-25-7-5-6-18-32(25)21-28(33)30-24-14-16-27(17-15-24)36-26-8-3-2-4-9-26/h2-4,8-17,25H,5-7,18-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251521
(4-((4-(2-oxo-2-(4-phenoxyphenylamino)ethyl)-1,4-di...)Show SMILES OC(=O)c1ccc(CN2CCCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 Show InChI InChI=1S/C27H29N3O4/c31-26(28-23-11-13-25(14-12-23)34-24-5-2-1-3-6-24)20-30-16-4-15-29(17-18-30)19-21-7-9-22(10-8-21)27(32)33/h1-3,5-14H,4,15-20H2,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251448
(4-(((3-((2-(4-benzylphenylamino)-2-oxoethyl)(methy...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O3/c1-30(20-24-9-13-25(14-10-24)28(33)34)17-6-18-31(2)21-27(32)29-26-15-11-23(12-16-26)19-22-7-4-3-5-8-22/h3-5,7-16H,6,17-21H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251500
(4-(((2,2-dimethyl-3-(methyl(2-oxo-2-(4-phenoxyphen...)Show SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC(C)(C)CN(C)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H35N3O4/c1-29(2,20-31(3)18-22-10-12-23(13-11-22)28(34)35)21-32(4)19-27(33)30-24-14-16-26(17-15-24)36-25-8-6-5-7-9-25/h5-17H,18-21H2,1-4H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251386
(4-(2-(methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylami...)Show SMILES CN(CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1)CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H33N3O4/c1-30(20-17-22-9-11-23(12-10-22)28(33)34)18-6-19-31(2)21-27(32)29-24-13-15-26(16-14-24)35-25-7-4-3-5-8-25/h3-5,7-16H,6,17-21H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251795
(2-((3-(benzyl(methyl)amino)propyl)(methyl)amino)-N...)Show SMILES CN(CCCN(C)Cc1ccccc1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O2/c1-28(20-22-10-5-3-6-11-22)18-9-19-29(2)21-26(30)27-23-14-16-25(17-15-23)31-24-12-7-4-8-13-24/h3-8,10-17H,9,18-21H2,1-2H3,(H,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251471
(4-(((3-((2-(4-(4-chlorophenoxy)phenylamino)-2-oxoe...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C27H30ClN3O4/c1-30(18-20-4-6-21(7-5-20)27(33)34)16-3-17-31(2)19-26(32)29-23-10-14-25(15-11-23)35-24-12-8-22(28)9-13-24/h4-15H,3,16-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251586
((S)-4-((2-((methyl(2-oxo-2-(4-phenoxyphenylamino)e...)Show SMILES CN(C[C@@H]1CCCN1Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C28H31N3O4/c1-30(19-24-6-5-17-31(24)18-21-9-11-22(12-10-21)28(33)34)20-27(32)29-23-13-15-26(16-14-23)35-25-7-3-2-4-8-25/h2-4,7-16,24H,5-6,17-20H2,1H3,(H,29,32)(H,33,34)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251796
(4-(methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino)...)Show SMILES CN(CCCN(C)CC(=O)Nc1ccc(Oc2ccccc2)cc1)CCCC(O)=O Show InChI InChI=1S/C23H31N3O4/c1-25(15-6-10-23(28)29)16-7-17-26(2)18-22(27)24-19-11-13-21(14-12-19)30-20-8-4-3-5-9-20/h3-5,8-9,11-14H,6-7,10,15-18H2,1-2H3,(H,24,27)(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251446
(4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H31N3O4/c1-29(19-21-9-11-22(12-10-21)27(32)33)17-6-18-30(2)20-26(31)28-23-13-15-25(16-14-23)34-24-7-4-3-5-8-24/h3-5,7-16H,6,17-20H2,1-2H3,(H,28,31)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251449
(4-(((3-((2-(4-(4-fluorophenoxy)phenylamino)-2-oxoe...)Show SMILES CN(CCCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-20-4-6-21(7-5-20)27(33)34)16-3-17-31(2)19-26(32)29-23-10-14-25(15-11-23)35-24-12-8-22(28)9-13-24/h4-15H,3,16-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251794
(2-((3-(dimethylamino)propyl)(methyl)amino)-N-(4-ph...)Show InChI InChI=1S/C20H27N3O2/c1-22(2)14-7-15-23(3)16-20(24)21-17-10-12-19(13-11-17)25-18-8-5-4-6-9-18/h4-6,8-13H,7,14-16H2,1-3H3,(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM24243
(2-amino-N-[4-(benzyloxy)phenyl]acetamide | Amino a...)Show InChI InChI=1S/C15H16N2O2/c16-10-15(18)17-13-6-8-14(9-7-13)19-11-12-4-2-1-3-5-12/h1-9H,10-11,16H2,(H,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251501
(4-((methyl(2-(methyl(2-oxo-2-(4-phenoxyphenylamino...)Show SMILES CN(CCN(C)Cc1ccc(cc1)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29N3O4/c1-28(18-20-8-10-21(11-9-20)26(31)32)16-17-29(2)19-25(30)27-22-12-14-24(15-13-22)33-23-6-4-3-5-7-23/h3-15H,16-19H2,1-2H3,(H,27,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251554
(4-((methyl(1-(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)Show SMILES CN(Cc1ccc(cc1)C(O)=O)C1CCCN(CC(=O)Nc2ccc(Oc3ccccc3)cc2)CC1 Show InChI InChI=1S/C29H33N3O4/c1-31(20-22-9-11-23(12-10-22)29(34)35)25-6-5-18-32(19-17-25)21-28(33)30-24-13-15-27(16-14-24)36-26-7-3-2-4-8-26/h2-4,7-16,25H,5-6,17-21H2,1H3,(H,30,33)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251794
(2-((3-(dimethylamino)propyl)(methyl)amino)-N-(4-ph...)Show InChI InChI=1S/C20H27N3O2/c1-22(2)14-7-15-23(3)16-20(24)21-17-10-12-19(13-11-17)25-18-8-5-4-6-9-18/h4-6,8-13H,7,14-16H2,1-3H3,(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251826
(3-fluoro-4-((methyl(3-(methyl(2-oxo-2-(4-phenoxyph...)Show SMILES CN(CCCN(C)Cc1ccc(cc1F)C(O)=O)CC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H30FN3O4/c1-30(18-21-10-9-20(27(33)34)17-25(21)28)15-6-16-31(2)19-26(32)29-22-11-13-24(14-12-22)35-23-7-4-3-5-8-23/h3-5,7-14,17H,6,15-16,18-19H2,1-2H3,(H,29,32)(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
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