Found 493 hits with Last Name = 'temml' and Initial = 'v' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50143314
![PNG](/data/jpeg/tenK5014/BindingDB_50143314.png) ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515333
![PNG](/data/jpeg/tenK5051/BindingDB_50515333.png) (CHEMBL4460815)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17FN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515321
![PNG](/data/jpeg/tenK5051/BindingDB_50515321.png) (CHEMBL4543232)Show SMILES O=C(N1CCc2ccccc2C1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(23-6-5-14-3-1-2-4-15(14)11-23)16-7-19(10-21-9-16)24-12-17-8-18(13-24)22-17/h1-4,7,9-10,17-18,22H,5-6,8,11-13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515320
![PNG](/data/jpeg/tenK5051/BindingDB_50515320.png) (CHEMBL4441630)Show SMILES Clc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17ClN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.0420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515326
![PNG](/data/jpeg/tenK5051/BindingDB_50515326.png) (CHEMBL4565381)Show SMILES Fc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17FN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515327
![PNG](/data/jpeg/tenK5051/BindingDB_50515327.png) (CHEMBL4556523)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c(F)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H16F2N4O/c18-11-1-2-16(15(19)4-11)22-17(24)10-3-14(7-20-6-10)23-8-12-5-13(9-23)21-12/h1-4,6-7,12-13,21H,5,8-9H2,(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.0510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515322
![PNG](/data/jpeg/tenK5051/BindingDB_50515322.png) (CHEMBL4444866)Show SMILES O=C(Nc1ccc2OCOc2c1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C18H18N4O3/c23-18(21-12-1-2-16-17(5-12)25-10-24-16)11-3-15(7-19-6-11)22-8-13-4-14(9-22)20-13/h1-3,5-7,13-14,20H,4,8-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.106 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50143314
![PNG](/data/jpeg/tenK5014/BindingDB_50143314.png) ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515334
![PNG](/data/jpeg/tenK5051/BindingDB_50515334.png) (CHEMBL4581470)Show SMILES O=C(N1CCCc2ccccc12)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(24-7-3-5-14-4-1-2-6-19(14)24)15-8-18(11-21-10-15)23-12-16-9-17(13-23)22-16/h1-2,4,6,8,10-11,16-17,22H,3,5,7,9,12-13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515325
![PNG](/data/jpeg/tenK5051/BindingDB_50515325.png) (CHEMBL4453342)Show SMILES Fc1ccccc1NC(=O)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C17H17FN4O/c18-15-3-1-2-4-16(15)21-17(23)11-5-14(8-19-7-11)22-9-12-6-13(10-22)20-12/h1-5,7-8,12-13,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.315 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515328
![PNG](/data/jpeg/tenK5051/BindingDB_50515328.png) (CHEMBL4435435)Show SMILES Ic1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17IN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.366 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515324
![PNG](/data/jpeg/tenK5051/BindingDB_50515324.png) (CHEMBL4447564)Show SMILES Clc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17ClN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.404 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515335
![PNG](/data/jpeg/tenK5051/BindingDB_50515335.png) (CHEMBL4532589)Show SMILES COc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:14:16:22:19| Show InChI InChI=1S/C18H20N4O2/c1-24-17-4-2-3-13(7-17)21-18(23)12-5-16(9-19-8-12)22-10-14-6-15(11-22)20-14/h2-5,7-9,14-15,20H,6,10-11H2,1H3,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515332
![PNG](/data/jpeg/tenK5051/BindingDB_50515332.png) (CHEMBL4462607)Show SMILES COc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1OC |TLB:13:15:21:18| Show InChI InChI=1S/C19H22N4O3/c1-25-17-4-3-13(7-18(17)26-2)22-19(24)12-5-16(9-20-8-12)23-10-14-6-15(11-23)21-14/h3-5,7-9,14-15,21H,6,10-11H2,1-2H3,(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.828 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50406804
![PNG](/data/jpeg/tenK5040/BindingDB_50406804.png) (CHEMBL4177192)Show SMILES Clc1ccc(cn1)N1CC2CCC(C1)N2 |TLB:4:7:14:10.11| Show InChI InChI=1S/C11H14ClN3/c12-11-4-3-10(5-13-11)15-6-8-1-2-9(7-15)14-8/h3-5,8-9,14H,1-2,6-7H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain cerebral cortex membrane incubated for 75 mins by scintillation counting method |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515331
![PNG](/data/jpeg/tenK5051/BindingDB_50515331.png) (CHEMBL4530364)Show SMILES COc1cc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc(OC)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C19H22N4O3/c1-25-17-5-13(6-18(7-17)26-2)22-19(24)12-3-16(9-20-8-12)23-10-14-4-15(11-23)21-14/h3,5-9,14-15,21H,4,10-11H2,1-2H3,(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 0.985 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515329
![PNG](/data/jpeg/tenK5051/BindingDB_50515329.png) (CHEMBL4571320)Show SMILES O=C(Nc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:13:15:21:18| Show InChI InChI=1S/C17H18N4O/c22-17(20-13-4-2-1-3-5-13)12-6-16(9-18-8-12)21-10-14-7-15(11-21)19-14/h1-6,8-9,14-15,19H,7,10-11H2,(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515330
![PNG](/data/jpeg/tenK5051/BindingDB_50515330.png) (CHEMBL4476500)Show SMILES CCc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:14:16:22:19| Show InChI InChI=1S/C19H22N4O/c1-2-13-4-3-5-15(6-13)22-19(24)14-7-18(10-20-9-14)23-11-16-8-17(12-23)21-16/h3-7,9-10,16-17,21H,2,8,11-12H2,1H3,(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50515323
![PNG](/data/jpeg/tenK5051/BindingDB_50515323.png) (CHEMBL4472986)Show SMILES O=C(NCc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C18H20N4O/c23-18(20-8-13-4-2-1-3-5-13)14-6-17(10-19-9-14)22-11-15-7-16(12-22)21-15/h1-6,9-10,15-16,21H,7-8,11-12H2,(H,20,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515321
![PNG](/data/jpeg/tenK5051/BindingDB_50515321.png) (CHEMBL4543232)Show SMILES O=C(N1CCc2ccccc2C1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(23-6-5-14-3-1-2-4-15(14)11-23)16-7-19(10-21-9-16)24-12-17-8-18(13-24)22-17/h1-4,7,9-10,17-18,22H,5-6,8,11-13H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515326
![PNG](/data/jpeg/tenK5051/BindingDB_50515326.png) (CHEMBL4565381)Show SMILES Fc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17FN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515327
![PNG](/data/jpeg/tenK5051/BindingDB_50515327.png) (CHEMBL4556523)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c(F)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H16F2N4O/c18-11-1-2-16(15(19)4-11)22-17(24)10-3-14(7-20-6-10)23-8-12-5-13(9-23)21-12/h1-4,6-7,12-13,21H,5,8-9H2,(H,22,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515320
![PNG](/data/jpeg/tenK5051/BindingDB_50515320.png) (CHEMBL4441630)Show SMILES Clc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17ClN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515334
![PNG](/data/jpeg/tenK5051/BindingDB_50515334.png) (CHEMBL4581470)Show SMILES O=C(N1CCCc2ccccc12)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(24-7-3-5-14-4-1-2-6-19(14)24)15-8-18(11-21-10-15)23-12-16-9-17(13-23)22-16/h1-2,4,6,8,10-11,16-17,22H,3,5,7,9,12-13H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515333
![PNG](/data/jpeg/tenK5051/BindingDB_50515333.png) (CHEMBL4460815)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17FN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515325
![PNG](/data/jpeg/tenK5051/BindingDB_50515325.png) (CHEMBL4453342)Show SMILES Fc1ccccc1NC(=O)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C17H17FN4O/c18-15-3-1-2-4-16(15)21-17(23)11-5-14(8-19-7-11)22-9-12-6-13(10-22)20-12/h1-5,7-8,12-13,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515328
![PNG](/data/jpeg/tenK5051/BindingDB_50515328.png) (CHEMBL4435435)Show SMILES Ic1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17IN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515322
![PNG](/data/jpeg/tenK5051/BindingDB_50515322.png) (CHEMBL4444866)Show SMILES O=C(Nc1ccc2OCOc2c1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C18H18N4O3/c23-18(21-12-1-2-16-17(5-12)25-10-24-16)11-3-15(7-19-6-11)22-8-13-4-14(9-22)20-13/h1-3,5-7,13-14,20H,4,8-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515324
![PNG](/data/jpeg/tenK5051/BindingDB_50515324.png) (CHEMBL4447564)Show SMILES Clc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17ClN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515329
![PNG](/data/jpeg/tenK5051/BindingDB_50515329.png) (CHEMBL4571320)Show SMILES O=C(Nc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:13:15:21:18| Show InChI InChI=1S/C17H18N4O/c22-17(20-13-4-2-1-3-5-13)12-6-16(9-18-8-12)21-10-14-7-15(11-21)19-14/h1-6,8-9,14-15,19H,7,10-11H2,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515335
![PNG](/data/jpeg/tenK5051/BindingDB_50515335.png) (CHEMBL4532589)Show SMILES COc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:14:16:22:19| Show InChI InChI=1S/C18H20N4O2/c1-24-17-4-2-3-13(7-17)21-18(23)12-5-16(9-19-8-12)22-10-14-6-15(11-22)20-14/h2-5,7-9,14-15,20H,6,10-11H2,1H3,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 265 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515330
![PNG](/data/jpeg/tenK5051/BindingDB_50515330.png) (CHEMBL4476500)Show SMILES CCc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:14:16:22:19| Show InChI InChI=1S/C19H22N4O/c1-2-13-4-3-5-15(6-13)22-19(24)14-7-18(10-20-9-14)23-11-16-8-17(12-23)21-16/h3-7,9-10,16-17,21H,2,8,11-12H2,1H3,(H,22,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 306 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515332
![PNG](/data/jpeg/tenK5051/BindingDB_50515332.png) (CHEMBL4462607)Show SMILES COc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1OC |TLB:13:15:21:18| Show InChI InChI=1S/C19H22N4O3/c1-25-17-4-3-13(7-18(17)26-2)22-19(24)12-5-16(9-20-8-12)23-10-14-6-15(11-23)21-14/h3-5,7-9,14-15,21H,6,10-11H2,1-2H3,(H,22,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 516 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515321
![PNG](/data/jpeg/tenK5051/BindingDB_50515321.png) (CHEMBL4543232)Show SMILES O=C(N1CCc2ccccc2C1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(23-6-5-14-3-1-2-4-15(14)11-23)16-7-19(10-21-9-16)24-12-17-8-18(13-24)22-17/h1-4,7,9-10,17-18,22H,5-6,8,11-13H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515323
![PNG](/data/jpeg/tenK5051/BindingDB_50515323.png) (CHEMBL4472986)Show SMILES O=C(NCc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C18H20N4O/c23-18(20-8-13-4-2-1-3-5-13)14-6-17(10-19-9-14)22-11-15-7-16(12-22)21-15/h1-6,9-10,15-16,21H,7-8,11-12H2,(H,20,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515323
![PNG](/data/jpeg/tenK5051/BindingDB_50515323.png) (CHEMBL4472986)Show SMILES O=C(NCc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C18H20N4O/c23-18(20-8-13-4-2-1-3-5-13)14-6-17(10-19-9-14)22-11-15-7-16(12-22)21-15/h1-6,9-10,15-16,21H,7-8,11-12H2,(H,20,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50515331
![PNG](/data/jpeg/tenK5051/BindingDB_50515331.png) (CHEMBL4530364)Show SMILES COc1cc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc(OC)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C19H22N4O3/c1-25-17-5-13(6-18(7-17)26-2)22-19(24)12-3-16(9-20-8-12)23-10-14-4-15(11-23)21-14/h3,5-9,14-15,21H,4,10-11H2,1-2H3,(H,22,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515332
![PNG](/data/jpeg/tenK5051/BindingDB_50515332.png) (CHEMBL4462607)Show SMILES COc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1OC |TLB:13:15:21:18| Show InChI InChI=1S/C19H22N4O3/c1-25-17-4-3-13(7-18(17)26-2)22-19(24)12-5-16(9-20-8-12)23-10-14-6-15(11-23)21-14/h3-5,7-9,14-15,21H,6,10-11H2,1-2H3,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515329
![PNG](/data/jpeg/tenK5051/BindingDB_50515329.png) (CHEMBL4571320)Show SMILES O=C(Nc1ccccc1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:13:15:21:18| Show InChI InChI=1S/C17H18N4O/c22-17(20-13-4-2-1-3-5-13)12-6-16(9-18-8-12)21-10-14-7-15(11-21)19-14/h1-6,8-9,14-15,19H,7,10-11H2,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515325
![PNG](/data/jpeg/tenK5051/BindingDB_50515325.png) (CHEMBL4453342)Show SMILES Fc1ccccc1NC(=O)c1cncc(c1)N1CC2CC(C1)N2 |TLB:14:16:22:19| Show InChI InChI=1S/C17H17FN4O/c18-15-3-1-2-4-16(15)21-17(23)11-5-14(8-19-7-11)22-9-12-6-13(10-22)20-12/h1-5,7-8,12-13,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515322
![PNG](/data/jpeg/tenK5051/BindingDB_50515322.png) (CHEMBL4444866)Show SMILES O=C(Nc1ccc2OCOc2c1)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C18H18N4O3/c23-18(21-12-1-2-16-17(5-12)25-10-24-16)11-3-15(7-19-6-11)22-8-13-4-14(9-22)20-13/h1-3,5-7,13-14,20H,4,8-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515324
![PNG](/data/jpeg/tenK5051/BindingDB_50515324.png) (CHEMBL4447564)Show SMILES Clc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17ClN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515320
![PNG](/data/jpeg/tenK5051/BindingDB_50515320.png) (CHEMBL4441630)Show SMILES Clc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17ClN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515328
![PNG](/data/jpeg/tenK5051/BindingDB_50515328.png) (CHEMBL4435435)Show SMILES Ic1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17IN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515326
![PNG](/data/jpeg/tenK5051/BindingDB_50515326.png) (CHEMBL4565381)Show SMILES Fc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:13:15:21:18| Show InChI InChI=1S/C17H17FN4O/c18-12-2-1-3-13(5-12)21-17(23)11-4-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 2.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515333
![PNG](/data/jpeg/tenK5051/BindingDB_50515333.png) (CHEMBL4460815)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H17FN4O/c18-12-1-3-13(4-2-12)21-17(23)11-5-16(8-19-7-11)22-9-14-6-15(10-22)20-14/h1-5,7-8,14-15,20H,6,9-10H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515331
![PNG](/data/jpeg/tenK5051/BindingDB_50515331.png) (CHEMBL4530364)Show SMILES COc1cc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc(OC)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C19H22N4O3/c1-25-17-5-13(6-18(7-17)26-2)22-19(24)12-3-16(9-20-8-12)23-10-14-4-15(11-23)21-14/h3,5-9,14-15,21H,4,10-11H2,1-2H3,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 4.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515327
![PNG](/data/jpeg/tenK5051/BindingDB_50515327.png) (CHEMBL4556523)Show SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c(F)c1 |TLB:12:14:20:17| Show InChI InChI=1S/C17H16F2N4O/c18-11-1-2-16(15(19)4-11)22-17(24)10-3-14(7-20-6-10)23-8-12-5-13(9-23)21-12/h1-4,6-7,12-13,21H,5,8-9H2,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515330
![PNG](/data/jpeg/tenK5051/BindingDB_50515330.png) (CHEMBL4476500)Show SMILES CCc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1 |TLB:14:16:22:19| Show InChI InChI=1S/C19H22N4O/c1-2-13-4-3-5-15(6-13)22-19(24)14-7-18(10-20-9-14)23-11-16-8-17(12-23)21-16/h3-7,9-10,16-17,21H,2,8,11-12H2,1H3,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50515334
![PNG](/data/jpeg/tenK5051/BindingDB_50515334.png) (CHEMBL4581470)Show SMILES O=C(N1CCCc2ccccc12)c1cncc(c1)N1CC2CC(C1)N2 |TLB:16:18:24:21| Show InChI InChI=1S/C20H22N4O/c25-20(24-7-3-5-14-4-1-2-6-19(14)24)15-8-18(11-21-10-15)23-12-16-9-17(13-23)22-16/h1-2,4,6,8,10-11,16-17,22H,3,5,7,9,12-13H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membrane |
Eur J Med Chem 180: 51-61 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.079 BindingDB Entry DOI: 10.7270/Q24Q7ZBT |
More data for this Ligand-Target Pair | |