Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554469![]() (CHEMBL4796694) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0510 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554470![]() (CHEMBL4752559) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554462![]() (CHEMBL4784029) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554475![]() (CHEMBL4757064) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554471![]() (CHEMBL4761454) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554479![]() (CHEMBL4741570) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554472![]() (CHEMBL4787488) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554464![]() (CHEMBL4750152) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554484![]() (CHEMBL4747825) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554480![]() (CHEMBL4757561) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554467![]() (CHEMBL4759088) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554477![]() (CHEMBL2426243) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539233![]() (CHEMBL4642625) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50154397![]() (CHEMBL3774760) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539213![]() (CHEMBL4637176) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50154397![]() (CHEMBL3774760) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554476![]() (CHEMBL4782633) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554465![]() (CHEMBL4776064) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539211![]() (CHEMBL4642915) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539244![]() (CHEMBL4648963) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539246![]() (CHEMBL4632439) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554483![]() (CHEMBL4085008) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554457![]() (CHEMBL4793575) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554473![]() (CHEMBL4754273) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539220![]() (CHEMBL4646043) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539221![]() (CHEMBL4637948) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539212![]() (CHEMBL4648770) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554481![]() (CHEMBL4743027) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554456![]() (CHEMBL4791705) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM601043![]() (4-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-tria...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50154387![]() (CHEMBL3774528) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM601048![]() (2-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554468![]() (CHEMBL4749659) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554478![]() (CHEMBL4763193) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539214![]() (CHEMBL4641132) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539243![]() (CHEMBL4637227) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50554474![]() (CHEMBL4761164) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM600981![]() (2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50427205![]() (CHEMBL2324854) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539222![]() (CHEMBL4643862) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539248![]() (CHEMBL4633059) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539223![]() (CHEMBL4634865) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539248![]() (CHEMBL4633059) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01391 BindingDB Entry DOI: 10.7270/Q2988BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539234![]() (CHEMBL4641550) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50539216![]() (CHEMBL4636343) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM600982![]() (2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-ethox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM601045![]() (4,5-dideuterio-1-[2,4-dichloro-3-(trifluoromethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM601033![]() (1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00162 BindingDB Entry DOI: 10.7270/Q2KH0SDZ | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM601001![]() (5-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2ZS31FM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoleoyl-protein carboxylesterase NOTUM (Homo sapiens (Human)) | BDBM50154370![]() (CHEMBL1689356) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126751 BindingDB Entry DOI: 10.7270/Q23X8B58 | |||||||||||
More data for this Ligand-Target Pair |
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