Compile Data Set for Download or QSAR

Found 227 hits with Last Name = 'abdel-aziz' and Initial = 'ni'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50342799 (5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-...) Show SMILES COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O Show InChI InChI=1S/C17H14N2O7/c1-24-13-7-10(8-14(25-2)15(13)26-3)18-16(20)11-5-4-9(19(22)23)6-12(11)17(18)21/h4-8H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50174201 (ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...) Show SMILES [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50070486 (CHEMBL3408781) Show SMILES COc1cc(CN2C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C18H16N2O7/c1-25-14-6-10(7-15(26-2)16(14)27-3)9-19-17(21)12-5-4-11(20(23)24)8-13(12)18(19)22/h4-8H,9H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50174201 (ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...) Show SMILES [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50070485 (CHEMBL3408782) Show SMILES COc1ccc(CN2C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H12N2O5/c1-23-12-5-2-10(3-6-12)9-17-15(19)13-7-4-11(18(21)22)8-14(13)16(17)20/h2-8H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM13066 (2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...) Show SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382212 (CHEMBL2024229) Show SMILES FC(F)(F)c1nn(c(c1\C=N\c1cc(cc(c1)C(F)(F)F)C(F)(F)F)-c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H13ClF9N3/c26-17-8-6-14(7-9-17)21-20(22(25(33,34)35)37-38(21)19-4-2-1-3-5-19)13-36-18-11-15(23(27,28)29)10-16(12-18)24(30,31)32/h1-13H/b36-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50070483 (CHEMBL3408784) Show SMILES COc1cc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc(OC)c1OC Show InChI InChI=1S/C18H15Cl2NO5/c1-24-14-4-9(5-15(25-2)16(14)26-3)8-21-17(22)10-6-12(19)13(20)7-11(10)18(21)23/h4-7H,8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382206 (CHEMBL2024222) Show SMILES COc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1OC |c:8,10| Show InChI InChI=1S/C19H14ClF3N2O2/c1-26-15-8-3-11(10-16(15)27-2)9-14-17(12-4-6-13(20)7-5-12)24-25-18(14)19(21,22)23/h3-10H,1-2H3/b14-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX-2 using arachidonic acid as substrate assessed as production of PGH2-alpha preincubated for 5 mins followed by addition of su...				Bioorg Med Chem 24: 2032-42 (2016) Article DOI: 10.1016/j.bmc.2016.03.032 BindingDB Entry DOI: 10.7270/Q2XK8HFX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50070482 (CHEMBL3408785) Show SMILES COc1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 Show InChI InChI=1S/C16H11Cl2NO3/c1-22-10-4-2-9(3-5-10)8-19-15(20)11-6-13(17)14(18)7-12(11)16(19)21/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2alpha production from PGH2 preincubated for 5 mins before arachidonic acid addition measured a...				Eur J Med Chem 92: 115-23 (2015) Article DOI: 10.1016/j.ejmech.2014.12.039 BindingDB Entry DOI: 10.7270/Q2GH9KN3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467263 (CHEMBL4282907) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C22H20N4O2S/c1-14(16-5-6-18-12-20(28-2)10-7-17(18)11-16)21-24-25-22(29)26(21)23-13-15-3-8-19(27)9-4-15/h3-14,27H,1-2H3,(H,25,29)/b23-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382211 (CHEMBL2024228) Show SMILES [O-][N+](=O)c1ccc(cc1)\N=C\c1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C23H14ClF3N4O2/c24-16-8-6-15(7-9-16)21-20(14-28-17-10-12-19(13-11-17)31(32)33)22(23(25,26)27)29-30(21)18-4-2-1-3-5-18/h1-14H/b28-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161267 (CHEMBL3785126) Show SMILES NS(=O)(=O)c1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-19(12-14-20)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382207 (CHEMBL2024223) Show SMILES [O-][N+](=O)c1cccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)c1 |c:10,12| Show InChI InChI=1S/C17H9ClF3N3O2/c18-12-6-4-11(5-7-12)15-14(16(23-22-15)17(19,20)21)9-10-2-1-3-13(8-10)24(25)26/h1-9H/b14-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161263 (CHEMBL3786373) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-17(12-14-20)15-26-21(29)16-28-22(30)24(27-23(28)31,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344875 (3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...) Show SMILES CCN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F |w:9.10| Show InChI InChI=1S/C24H21ClF3N3O/c1-2-30-13-12-21(32)17(15-30)14-20-22(16-8-10-18(25)11-9-16)31(19-6-4-3-5-7-19)29-23(20)24(26,27)28/h3-11,14H,2,12-13,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344879 (2-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...) Show SMILES FC(F)(F)c1nn(c(c1C=C1CCCC1=O)-c1ccc(Cl)cc1)-c1ccccc1 |w:9.9| Show InChI InChI=1S/C22H16ClF3N2O/c23-16-11-9-14(10-12-16)20-18(13-15-5-4-8-19(15)29)21(22(24,25)26)27-28(20)17-6-2-1-3-7-17/h1-3,6-7,9-13H,4-5,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344885 (1-(4-Chlorophenyl)-2-(2-(3,5-bis(trifluoromethyl)p...) Show SMILES FC(F)(F)C(=O)C(=NNc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1ccc(Cl)cc1 |w:7.7| Show InChI InChI=1S/C18H8ClF9N2O2/c19-11-3-1-8(2-4-11)14(31)13(15(32)18(26,27)28)30-29-12-6-9(16(20,21)22)5-10(7-12)17(23,24)25/h1-7,29H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344879 (2-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...) Show SMILES FC(F)(F)c1nn(c(c1C=C1CCCC1=O)-c1ccc(Cl)cc1)-c1ccccc1 |w:9.9| Show InChI InChI=1S/C22H16ClF3N2O/c23-16-11-9-14(10-12-16)20-18(13-15-5-4-8-19(15)29)21(22(24,25)26)27-28(20)17-6-2-1-3-7-17/h1-3,6-7,9-13H,4-5,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344875 (3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...) Show SMILES CCN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F |w:9.10| Show InChI InChI=1S/C24H21ClF3N3O/c1-2-30-13-12-21(32)17(15-30)14-20-22(16-8-10-18(25)11-9-16)31(19-6-4-3-5-7-19)29-23(20)24(26,27)28/h3-11,14H,2,12-13,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382204 (CHEMBL2024220) Show SMILES Oc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1 |c:7,9| Show InChI InChI=1S/C17H10ClF3N2O/c18-12-5-3-11(4-6-12)15-14(16(23-22-15)17(19,20)21)9-10-1-7-13(24)8-2-10/h1-9,24H/b14-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382200 (CHEMBL2024216) Show SMILES COc1ccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1OC Show InChI InChI=1S/C19H14ClF3O4/c1-26-15-8-3-11(10-16(15)27-2)9-14(18(25)19(21,22)23)17(24)12-4-6-13(20)7-5-12/h3-10H,1-2H3/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344878 (5-(4-chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H...) Show SMILES FC(F)(F)c1nn(c(c1C=O)-c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C17H10ClF3N2O/c18-12-8-6-11(7-9-12)15-14(10-24)16(17(19,20)21)22-23(15)13-4-2-1-3-5-13/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344878 (5-(4-chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H...) Show SMILES FC(F)(F)c1nn(c(c1C=O)-c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C17H10ClF3N2O/c18-12-8-6-11(7-9-12)15-14(10-24)16(17(19,20)21)22-23(15)13-4-2-1-3-5-13/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161264 (CHEMBL3786688) Show SMILES COc1cc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C27H27N3O6/c1-34-21-14-18(15-22(35-2)24(21)36-3)16-28-23(31)17-30-25(32)27(29-26(30)33,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-15H,16-17H2,1-3H3,(H,28,31)(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467259 (CHEMBL4280674) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(O)cc1 Show InChI InChI=1S/C21H18N2O3/c1-13(15-3-4-17-12-19(25-2)10-7-16(17)11-15)20-22-23-21(26-20)14-5-8-18(24)9-6-14/h3-13,24H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382201 (CHEMBL2024217) Show SMILES [O-][N+](=O)c1cccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)c1 Show InChI InChI=1S/C17H9ClF3NO4/c18-12-6-4-11(5-7-12)15(23)14(16(24)17(19,20)21)9-10-2-1-3-13(8-10)22(25)26/h1-9H/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161259 (CHEMBL3785358) Show SMILES NS(=O)(=O)c1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C23H20N4O5S/c24-33(31,32)19-13-11-18(12-14-19)25-20(28)15-27-21(29)23(26-22(27)30,16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,15H2,(H,25,28)(H,26,30)(H2,24,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467271 (CHEMBL4293512) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1cccc(Br)c1 Show InChI InChI=1S/C22H19BrN4OS/c1-14(16-6-7-18-12-20(28-2)9-8-17(18)11-16)21-25-26-22(29)27(21)24-13-15-4-3-5-19(23)10-15/h3-14H,1-2H3,(H,26,29)/b24-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467270 (CHEMBL4286289) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1ccccc1 Show InChI InChI=1S/C22H20N4OS/c1-15(17-8-9-19-13-20(27-2)11-10-18(19)12-17)21-24-25-22(28)26(21)23-14-16-6-4-3-5-7-16/h3-15H,1-2H3,(H,25,28)/b23-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344883 (1-(4-Chlorophenyl)-2-(2-(4-nitrophenyl)hydrazone)-...) Show SMILES [O-][N+](=O)c1ccc(NN=C(C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 |w:8.7| Show InChI InChI=1S/C16H9ClF3N3O4/c17-10-3-1-9(2-4-10)14(24)13(15(25)16(18,19)20)22-21-11-5-7-12(8-6-11)23(26)27/h1-8,21H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344880 (1-(4-Chlorophenyl)-2-(2-(2-chlorophenyl)hydrazone)...) Show SMILES FC(F)(F)C(=O)C(=NNc1ccccc1Cl)C(=O)c1ccc(Cl)cc1 |w:7.7| Show InChI InChI=1S/C16H9Cl2F3N2O2/c17-10-7-5-9(6-8-10)14(24)13(15(25)16(19,20)21)23-22-12-4-2-1-3-11(12)18/h1-8,22H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344881 (1-(4-Chlorophenyl)-2-(2-(4-chlorophenyl)hydrazone)...) Show SMILES FC(F)(F)C(=O)C(=NNc1ccc(Cl)cc1)C(=O)c1ccc(Cl)cc1 |w:7.7| Show InChI InChI=1S/C16H9Cl2F3N2O2/c17-10-3-1-9(2-4-10)14(24)13(15(25)16(19,20)21)23-22-12-7-5-11(18)6-8-12/h1-8,22H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50344882 (1-(4-Chlorophenyl)-2-(2-(4-bromophenyl)hydrazone)-...) Show SMILES FC(F)(F)C(=O)C(=NNc1ccc(Br)cc1)C(=O)c1ccc(Cl)cc1 |w:7.7| Show InChI InChI=1S/C16H9BrClF3N2O2/c17-10-3-7-12(8-4-10)22-23-13(15(25)16(19,20)21)14(24)9-1-5-11(18)6-2-9/h1-8,22H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161266 (CHEMBL3786019) Show SMILES COc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C25H23N3O4/c1-32-21-14-12-20(13-15-21)26-22(29)16-17-28-23(30)25(27-24(28)31,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467261 (CHEMBL4277073) Show SMILES [#6]-[#8]-c1ccc2cc(ccc2c1)-[#6](-[#6])-[#6](=O)-[#7]\[#7]=[#6]-1\[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C20H24N2O2/c1-14(20(23)22-21-18-6-4-3-5-7-18)15-8-9-17-13-19(24-2)11-10-16(17)12-15/h8-14H,3-7H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382196 (CHEMBL2024214) Show SMILES Oc1ccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C17H10ClF3O3/c18-12-5-3-11(4-6-12)15(23)14(16(24)17(19,20)21)9-10-1-7-13(22)8-2-10/h1-9,22H/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467260 (CHEMBL4288580) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(C)cc1 Show InChI InChI=1S/C22H20N2O2/c1-14-4-6-16(7-5-14)22-24-23-21(26-22)15(2)17-8-9-19-13-20(25-3)11-10-18(19)12-17/h4-13,15H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161261 (CHEMBL2139982) Show SMILES COc1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C25H23N3O4/c1-32-21-14-12-18(13-15-21)16-26-22(29)17-28-23(30)25(27-24(28)31,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50161270 (CHEMBL3786565) Show SMILES COc1ccc(CNC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C26H25N3O4/c1-33-22-14-12-19(13-15-22)18-27-23(30)16-17-29-24(31)26(28-25(29)32,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15H,16-18H2,1H3,(H,27,30)(H,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) Article DOI: 10.1016/j.ejmech.2016.03.011 BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467264 (CHEMBL4284126) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H17N3O4/c1-13(15-3-4-17-12-19(27-2)10-7-16(17)11-15)20-22-23-21(28-20)14-5-8-18(9-6-14)24(25)26/h3-13H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50382205 (CHEMBL2024221) Show SMILES COc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1 |c:8,10| Show InChI InChI=1S/C18H12ClF3N2O/c1-25-14-8-2-11(3-9-14)10-15-16(12-4-6-13(19)7-5-12)23-24-17(15)18(20,21)22/h2-10H,1H3/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem 20: 3306-16 (2012) Article DOI: 10.1016/j.bmc.2012.03.044 BindingDB Entry DOI: 10.7270/Q2MK6DWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50174201 (ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...) Show SMILES [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mansoura Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassay				Bioorg Med Chem 19: 3416-24 (2011) Article DOI: 10.1016/j.bmc.2011.04.027 BindingDB Entry DOI: 10.7270/Q2JM29ZT
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50467269 (CHEMBL3754769) Show SMILES COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1N Show InChI InChI=1S/C15H16N4OS/c1-9(14-17-18-15(21)19(14)16)10-3-4-12-8-13(20-2)6-5-11(12)7-10/h3-9H,16H2,1-2H3,(H,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 using arachidonic acid as substrate incubated for 5 mins followed by substrate addition measured after 2 mins by colorimetri...				Eur J Med Chem 158: 134-143 (2018) Article DOI: 10.1016/j.ejmech.2018.09.007 BindingDB Entry DOI: 10.7270/Q2RF5XQD
					More data for this Ligand-Target Pair

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