Compile Data Set for Download or QSAR

Found 26 hits with Last Name = 'ahola' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178975 (4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3[nH]c(cc3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Cl2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178971 ((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...) Show SMILES N[C@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O Show InChI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178971 ((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...) Show SMILES N[C@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O Show InChI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair				3D Structure (docked)
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178974 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3[nH]c(cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Br2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178975 (4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3[nH]c(cc3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Cl2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178974 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3[nH]c(cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Br2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178972 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3CC(Cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H18Br2O4/c1-9(2)13-8-12(3-4-16(13)22)25-18-15(20)7-10-5-11(19(23)24)6-14(10)17(18)21/h3-4,7-9,11,22H,5-6H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178970 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(ccc3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO4/c1-11(2)16-10-14(5-8-19(16)23)26-20-12(3)9-18-15(13(20)4)6-7-17(22-18)21(24)25/h5-11,23H,1-4H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178972 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3CC(Cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H18Br2O4/c1-9(2)13-8-12(3-4-16(13)22)25-18-15(20)7-10-5-11(19(23)24)6-14(10)17(18)21/h3-4,7-9,11,22H,5-6H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178976 (5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3nc(cc(O)c3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H15Br2NO5/c1-8(2)10-5-9(3-4-14(10)23)27-18-11(20)6-12-16(17(18)21)15(24)7-13(22-12)19(25)26/h3-8,23H,1-2H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178970 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(ccc3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO4/c1-11(2)16-10-14(5-8-19(16)23)26-20-12(3)9-18-15(13(20)4)6-7-17(22-18)21(24)25/h5-11,23H,1-4H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50241363 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(cc(O)c3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO5/c1-10(2)14-8-13(5-6-17(14)23)27-20-11(3)7-15-19(12(20)4)18(24)9-16(22-15)21(25)26/h5-10,23H,1-4H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178976 (5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3nc(cc(O)c3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H15Br2NO5/c1-8(2)10-5-9(3-4-14(10)23)27-18-11(20)6-12-16(17(18)21)15(24)7-13(22-12)19(25)26/h3-8,23H,1-2H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50241363 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(cc(O)c3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO5/c1-10(2)14-8-13(5-6-17(14)23)27-20-11(3)7-15-19(12(20)4)18(24)9-16(22-15)21(25)26/h5-10,23H,1-4H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50241362 (5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3nc(cc(O)c3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C19H15Cl2NO5/c1-8(2)10-5-9(3-4-14(10)23)27-18-11(20)6-12-16(17(18)21)15(24)7-13(22-12)19(25)26/h3-8,23H,1-2H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRbeta1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50241362 (5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3nc(cc(O)c3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C19H15Cl2NO5/c1-8(2)10-5-9(3-4-14(10)23)27-18-11(20)6-12-16(17(18)21)15(24)7-13(22-12)19(25)26/h3-8,23H,1-2H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Inhibition of human TRalpha1 by radioligand binding assay				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178971 ((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...) Show SMILES N[C@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O Show InChI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-alpha-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178975 (4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3[nH]c(cc3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Cl2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-beta-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178971 ((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...) Show SMILES N[C@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O Show InChI InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-beta-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair				3D Structure (docked)
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178975 (4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc3[nH]c(cc3c2Cl)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Cl2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-alpha-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178972 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3CC(Cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H18Br2O4/c1-9(2)13-8-12(3-4-16(13)22)25-18-15(20)7-10-5-11(19(23)24)6-14(10)17(18)21/h3-4,7-9,11,22H,5-6H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-alpha-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178972 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3CC(Cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C19H18Br2O4/c1-9(2)13-8-12(3-4-16(13)22)25-18-15(20)7-10-5-11(19(23)24)6-14(10)17(18)21/h3-4,7-9,11,22H,5-6H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-beta-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178974 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3[nH]c(cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Br2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-alpha-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50178970 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(ccc3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO4/c1-11(2)16-10-14(5-8-19(16)23)26-20-12(3)9-18-15(13(20)4)6-7-17(22-18)21(24)25/h5-11,23H,1-4H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-alpha-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178970 (6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethylquino...) Show SMILES CC(C)c1cc(Oc2c(C)cc3nc(ccc3c2C)C(O)=O)ccc1O Show InChI InChI=1S/C21H21NO4/c1-11(2)16-10-14(5-8-19(16)23)26-20-12(3)9-18-15(13(20)4)6-7-17(22-18)21(24)25/h5-11,23H,1-4H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-beta-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50178974 (4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...) Show SMILES CC(C)c1cc(Oc2c(Br)cc3[nH]c(cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C18H15Br2NO4/c1-8(2)10-5-9(3-4-15(10)22)25-17-12(19)7-13-11(16(17)20)6-14(21-13)18(23)24/h3-8,21-22H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Karo Bio AB Curated by ChEMBL					Assay Description Efficacy against TRAF-beta-1 reporter cells				Bioorg Med Chem Lett 16: 1240-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.077 BindingDB Entry DOI: 10.7270/Q2T72H1W
					More data for this Ligand-Target Pair