Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'akhila' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142589 (CHEMBL47638 | N-{4-[2-(4-Chloro-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C17H13ClF3N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142592 (CHEMBL43842 | N-{4-[2-(4-Bromo-phenyl)-5-trifluoro...) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C18H13BrF3N3O/c1-11(26)23-14-6-2-12(3-7-14)16-10-17(18(20,21)22)24-25(16)15-8-4-13(19)5-9-15/h2-10H,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142582 (4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(18,19)20)11-2-4-12(21)5-3-11/h2-10H,21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142582 (4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(18,19)20)11-2-4-12(21)5-3-11/h2-10H,21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142583 (CHEMBL45247 | N-{4-[2-(4-Chloro-phenyl)-5-difluoro...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Cl)cc1)C(F)F Show InChI InChI=1S/C17H14ClF2N3O2S/c1-26(24,25)22-13-6-2-11(3-7-13)16-10-15(17(19)20)21-23(16)14-8-4-12(18)5-9-14/h2-10,17,22H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142591 (CHEMBL297788 | N-{4-[2-(4-Bromo-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C17H13BrF3N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142587 (CHEMBL45387 | N-{4-[2-(4-Chloro-phenyl)-5-methyl-2...) Show SMILES Cc1cc(-c2ccc(NS(C)(=O)=O)cc2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H16ClN3O2S/c1-12-11-17(21(19-12)16-9-5-14(18)6-10-16)13-3-7-15(8-4-13)20-24(2,22)23/h3-11,20H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142586 (CHEMBL298031 | N-{4-[2-(4-Methoxy-phenyl)-5-triflu...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(NS(C)(=O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S/c1-27-15-9-7-14(8-10-15)24-16(11-17(22-24)18(19,20)21)12-3-5-13(6-4-12)23-28(2,25)26/h3-11,23H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142580 (CHEMBL418516 | N-{4-[2-(4-Dimethylamino-phenyl)-5-...) Show SMILES CN(C)c1ccc(cc1)-n1nc(cc1-c1ccc(NS(C)(=O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C19H19F3N4O2S/c1-25(2)15-8-10-16(11-9-15)26-17(12-18(23-26)19(20,21)22)13-4-6-14(7-5-13)24-29(3,27)28/h4-12,24H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142584 (CHEMBL47447 | N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H...) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(C)nn1-c1ccc(Br)cc1 Show InChI InChI=1S/C18H16BrN3O/c1-12-11-18(14-3-7-16(8-4-14)20-13(2)23)22(21-12)17-9-5-15(19)6-10-17/h3-11H,1-2H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142588 (CHEMBL442548 | N-{4-[2-(4-Fluoro-phenyl)-5-trifluo...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H13F4N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142585 (CHEMBL45331 | N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H...) Show SMILES Cc1cc(-c2ccc(NS(C)(=O)=O)cc2)n(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c1-12-11-17(21(19-12)16-9-5-14(18)6-10-16)13-3-7-15(8-4-13)20-24(2,22)23/h3-11,20H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142586 (CHEMBL298031 | N-{4-[2-(4-Methoxy-phenyl)-5-triflu...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(NS(C)(=O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S/c1-27-15-9-7-14(8-10-15)24-16(11-17(22-24)18(19,20)21)12-3-5-13(6-4-12)23-28(2,25)26/h3-11,23H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142581 (CHEMBL297527 | N-{4-[2-(4-Amino-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H15F3N4O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(18,19)20)22-24(15)14-8-4-12(21)5-9-14/h2-10,23H,21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142590 (CHEMBL44319 | N-[4-(2-Phenyl-5-trifluoromethyl-2H-...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-26(24,25)22-13-9-7-12(8-10-13)15-11-16(17(18,19)20)21-23(15)14-5-3-2-4-6-14/h2-11,22H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142580 (CHEMBL418516 | N-{4-[2-(4-Dimethylamino-phenyl)-5-...) Show SMILES CN(C)c1ccc(cc1)-n1nc(cc1-c1ccc(NS(C)(=O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C19H19F3N4O2S/c1-25(2)15-8-10-16(11-9-15)26-17(12-18(23-26)19(20,21)22)13-4-6-14(7-5-13)24-29(3,27)28/h4-12,24H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142592 (CHEMBL43842 | N-{4-[2-(4-Bromo-phenyl)-5-trifluoro...) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C18H13BrF3N3O/c1-11(26)23-14-6-2-12(3-7-14)16-10-17(18(20,21)22)24-25(16)15-8-4-13(19)5-9-15/h2-10H,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142591 (CHEMBL297788 | N-{4-[2-(4-Bromo-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C17H13BrF3N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	7.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50142593 (CHEMBL296098 | N-{4-[5-Difluoromethyl-2-(4-fluoro-...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(F)cc1)C(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-26(24,25)22-13-6-2-11(3-7-13)16-10-15(17(19)20)21-23(16)14-8-4-12(18)5-9-14/h2-10,17,22H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142584 (CHEMBL47447 | N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H...) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(C)nn1-c1ccc(Br)cc1 Show InChI InChI=1S/C18H16BrN3O/c1-12-11-18(14-3-7-16(8-4-14)20-13(2)23)22(21-12)17-9-5-15(19)6-10-17/h3-11H,1-2H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142589 (CHEMBL47638 | N-{4-[2-(4-Chloro-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C17H13ClF3N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142588 (CHEMBL442548 | N-{4-[2-(4-Fluoro-phenyl)-5-trifluo...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H13F4N3O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(19,20)21)22-24(15)14-8-4-12(18)5-9-14/h2-10,23H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142581 (CHEMBL297527 | N-{4-[2-(4-Amino-phenyl)-5-trifluor...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H15F3N4O2S/c1-27(25,26)23-13-6-2-11(3-7-13)15-10-16(17(18,19)20)22-24(15)14-8-4-12(21)5-9-14/h2-10,23H,21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142583 (CHEMBL45247 | N-{4-[2-(4-Chloro-phenyl)-5-difluoro...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccc(Cl)cc1)C(F)F Show InChI InChI=1S/C17H14ClF2N3O2S/c1-26(24,25)22-13-6-2-11(3-7-13)16-10-15(17(19)20)21-23(16)14-8-4-12(18)5-9-14/h2-10,17,22H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142585 (CHEMBL45331 | N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H...) Show SMILES Cc1cc(-c2ccc(NS(C)(=O)=O)cc2)n(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c1-12-11-17(21(19-12)16-9-5-14(18)6-10-16)13-3-7-15(8-4-13)20-24(2,22)23/h3-11,20H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142590 (CHEMBL44319 | N-[4-(2-Phenyl-5-trifluoromethyl-2H-...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(nn1-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-26(24,25)22-13-9-7-12(8-10-13)15-11-16(17(18,19)20)21-23(15)14-5-3-2-4-6-14/h2-11,22H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50142587 (CHEMBL45387 | N-{4-[2-(4-Chloro-phenyl)-5-methyl-2...) Show SMILES Cc1cc(-c2ccc(NS(C)(=O)=O)cc2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H16ClN3O2S/c1-12-11-17(21(19-12)16-9-5-14(18)6-10-16)13-3-7-15(8-4-13)20-24(2,22)23/h3-11,20H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair