Compile Data Set for Download or QSAR

Found 374 hits with Last Name = 'andersen' and Initial = 'kt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324399 ((E)-4-(6-iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324404 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H19N3O5/c33-28-25-18-22(20-6-2-1-3-7-20)12-15-26(25)30-27(16-9-19-5-4-8-24(17-19)32(36)37)31(28)23-13-10-21(11-14-23)29(34)35/h1-18H,(H,34,35)/b16-9+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324426 ((E)-4-(6-iodo-2-(4-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-6-11-20-19(13-16)22(28)26(17-9-4-15(5-10-17)23(29)30)21(25-20)12-3-14-1-7-18(8-2-14)27(31)32/h1-13H,(H,29,30)/b12-3+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324405 ((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324392 ((E)-4-(6-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Cl)cc2c1=O Show InChI InChI=1S/C23H14ClN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324398 ((E)-4-(6-Bromo-2-(3-nitrostyryl)-4-oxoquinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Br)cc2c1=O Show InChI InChI=1S/C23H14BrN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324397 ((E)-4-(6-Fluoro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(F)cc2c1=O Show InChI InChI=1S/C23H14FN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324428 ((E)-3-(6-Iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-8-9-20-19(13-16)22(28)26(17-5-2-4-15(12-17)23(29)30)21(25-20)10-7-14-3-1-6-18(11-14)27(31)32/h1-13H,(H,29,30)/b10-7+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324409 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...) Show SMILES CCCc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-2-4-17-7-13-23-22(16-17)25(30)28(20-11-9-19(10-12-20)26(31)32)24(27-23)14-8-18-5-3-6-21(15-18)29(33)34/h3,5-16H,2,4H2,1H3,(H,31,32)/b14-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324404 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H19N3O5/c33-28-25-18-22(20-6-2-1-3-7-20)12-15-26(25)30-27(16-9-19-5-4-8-24(17-19)32(36)37)31(28)23-13-10-21(11-14-23)29(34)35/h1-18H,(H,34,35)/b16-9+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324445 ((E)-6-iodo-3-(2-methoxyphenyl)-2-(2-(pyridin-3-yl)...) Show SMILES COc1ccccc1-n1c(\C=C\c2cccnc2)nc2ccc(I)cc2c1=O |(9.99,5.86,;9.99,4.32,;11.33,3.56,;12.66,4.34,;14.01,3.58,;14.01,2.04,;12.68,1.26,;11.34,2.03,;10.01,1.26,;10.02,-.29,;11.36,-1.06,;11.36,-2.6,;12.69,-3.36,;14.01,-2.58,;15.35,-3.34,;15.35,-4.89,;14.02,-5.66,;12.69,-4.9,;8.68,-1.07,;7.35,-.3,;6,-1.07,;4.67,-.3,;4.67,1.24,;3.34,2.01,;6,2.01,;7.34,1.24,;8.67,2.03,;8.66,3.57,)| Show InChI InChI=1S/C22H16IN3O2/c1-28-20-7-3-2-6-19(20)26-21(11-8-15-5-4-12-24-14-15)25-18-10-9-16(23)13-17(18)22(26)27/h2-14H,1H3/b11-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324411 (4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O Show InChI InChI=1S/C31H21N3O5/c35-30-27-20-23(10-9-21-5-2-1-3-6-21)11-17-28(27)32-29(18-12-22-7-4-8-26(19-22)34(38)39)33(30)25-15-13-24(14-16-25)31(36)37/h1-20H,(H,36,37)/b10-9+,18-12+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324405 ((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324473 ((E)-3-(2-methoxyphenyl)-2-(2-nitrostyryl)quinazoli...) Show SMILES COc1ccccc1-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O |(33.08,.19,;31.74,.96,;31.74,2.5,;33.07,3.27,;33.06,4.81,;31.73,5.58,;30.4,4.8,;30.4,3.27,;29.07,2.5,;29.08,.94,;30.41,.19,;30.42,-1.37,;31.76,-2.13,;33.07,-1.35,;34.41,-2.12,;34.42,-3.66,;33.09,-4.43,;31.75,-3.67,;30.42,-4.44,;29.08,-3.67,;30.42,-5.98,;27.74,.16,;26.4,.93,;25.05,.16,;23.72,.93,;23.72,2.47,;25.05,3.25,;26.39,2.48,;27.72,3.27,;27.71,4.81,)| Show InChI InChI=1S/C23H17N3O4/c1-30-21-13-7-6-12-20(21)25-22(24-18-10-4-3-9-17(18)23(25)27)15-14-16-8-2-5-11-19(16)26(28)29/h2-15H,1H3/b15-14+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324473 ((E)-3-(2-methoxyphenyl)-2-(2-nitrostyryl)quinazoli...) Show SMILES COc1ccccc1-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O |(33.08,.19,;31.74,.96,;31.74,2.5,;33.07,3.27,;33.06,4.81,;31.73,5.58,;30.4,4.8,;30.4,3.27,;29.07,2.5,;29.08,.94,;30.41,.19,;30.42,-1.37,;31.76,-2.13,;33.07,-1.35,;34.41,-2.12,;34.42,-3.66,;33.09,-4.43,;31.75,-3.67,;30.42,-4.44,;29.08,-3.67,;30.42,-5.98,;27.74,.16,;26.4,.93,;25.05,.16,;23.72,.93,;23.72,2.47,;25.05,3.25,;26.39,2.48,;27.72,3.27,;27.71,4.81,)| Show InChI InChI=1S/C23H17N3O4/c1-30-21-13-7-6-12-20(21)25-22(24-18-10-4-3-9-17(18)23(25)27)15-14-16-8-2-5-11-19(16)26(28)29/h2-15H,1H3/b15-14+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324400 ((E)-4-(6-Methyl-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES Cc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O5/c1-15-5-11-21-20(13-15)23(28)26(18-9-7-17(8-10-18)24(29)30)22(25-21)12-6-16-3-2-4-19(14-16)27(31)32/h2-14H,1H3,(H,29,30)/b12-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324405 ((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324404 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H19N3O5/c33-28-25-18-22(20-6-2-1-3-7-20)12-15-26(25)30-27(16-9-19-5-4-8-24(17-19)32(36)37)31(28)23-13-10-21(11-14-23)29(34)35/h1-18H,(H,34,35)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324463 ((E)-3-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-9-2-3-10-19(18)24-21(13-12-15-6-1-4-11-20(15)26(30)31)25(22)17-8-5-7-16(14-17)23(28)29/h1-14H,(H,28,29)/b13-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324410 ((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1 Show InChI InChI=1S/C27H17N3O5S/c31-26-22-16-19(24-5-2-14-36-24)9-12-23(22)28-25(13-6-17-3-1-4-21(15-17)30(34)35)29(26)20-10-7-18(8-11-20)27(32)33/h1-16H,(H,32,33)/b13-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324401 ((E)-4-(6-Methoxy-2-(3-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324399 ((E)-4-(6-iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324452 ((E)-4-(6-Iodo-4-oxo-2-(2-(pyridin-3-yl)vinyl)quina...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccnc2)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C22H14IN3O3/c23-16-6-9-19-18(12-16)21(27)26(17-7-4-15(5-8-17)22(28)29)20(25-19)10-3-14-2-1-11-24-13-14/h1-13H,(H,28,29)/b10-3+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324408 ((E)-4-(6-Isopropyl-2-(3-nitrostyryl)-4-oxoquinazol...) Show SMILES CC(C)c1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C26H21N3O5/c1-16(2)19-9-12-23-22(15-19)25(30)28(20-10-7-18(8-11-20)26(31)32)24(27-23)13-6-17-4-3-5-21(14-17)29(33)34/h3-16H,1-2H3,(H,31,32)/b13-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324461 ((E)-4-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-6-2-3-7-19(18)24-21(14-11-15-5-1-4-8-20(15)26(30)31)25(22)17-12-9-16(10-13-17)23(28)29/h1-14H,(H,28,29)/b14-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324453 ((E)-3-(6-Iodo-4-oxo-2-(2-(pyridin-3-yl)vinyl)quina...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2cccnc2)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C22H14IN3O3/c23-16-7-8-19-18(12-16)21(27)26(17-5-1-4-15(11-17)22(28)29)20(25-19)9-6-14-3-2-10-24-13-14/h1-13H,(H,28,29)/b9-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324392 ((E)-4-(6-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Cl)cc2c1=O Show InChI InChI=1S/C23H14ClN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324397 ((E)-4-(6-Fluoro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(F)cc2c1=O Show InChI InChI=1S/C23H14FN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324473 ((E)-3-(2-methoxyphenyl)-2-(2-nitrostyryl)quinazoli...) Show SMILES COc1ccccc1-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O |(33.08,.19,;31.74,.96,;31.74,2.5,;33.07,3.27,;33.06,4.81,;31.73,5.58,;30.4,4.8,;30.4,3.27,;29.07,2.5,;29.08,.94,;30.41,.19,;30.42,-1.37,;31.76,-2.13,;33.07,-1.35,;34.41,-2.12,;34.42,-3.66,;33.09,-4.43,;31.75,-3.67,;30.42,-4.44,;29.08,-3.67,;30.42,-5.98,;27.74,.16,;26.4,.93,;25.05,.16,;23.72,.93,;23.72,2.47,;25.05,3.25,;26.39,2.48,;27.72,3.27,;27.71,4.81,)| Show InChI InChI=1S/C23H17N3O4/c1-30-21-13-7-6-12-20(21)25-22(24-18-10-4-3-9-17(18)23(25)27)15-14-16-8-2-5-11-19(16)26(28)29/h2-15H,1H3/b15-14+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324461 ((E)-4-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-6-2-3-7-19(18)24-21(14-11-15-5-1-4-8-20(15)26(30)31)25(22)17-12-9-16(10-13-17)23(28)29/h1-14H,(H,28,29)/b14-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324428 ((E)-3-(6-Iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-8-9-20-19(13-16)22(28)26(17-5-2-4-15(12-17)23(29)30)21(25-20)10-7-14-3-1-6-18(11-14)27(31)32/h1-13H,(H,29,30)/b10-7+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324463 ((E)-3-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-9-2-3-10-19(18)24-21(13-12-15-6-1-4-11-20(15)26(30)31)25(22)17-8-5-7-16(14-17)23(28)29/h1-14H,(H,28,29)/b13-12+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324398 ((E)-4-(6-Bromo-2-(3-nitrostyryl)-4-oxoquinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Br)cc2c1=O Show InChI InChI=1S/C23H14BrN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324396 ((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O Show InChI InChI=1S/C23H13Cl2N3O5/c24-15-11-18-21(19(25)12-15)26-20(10-3-13-1-6-17(7-2-13)28(32)33)27(22(18)29)16-8-4-14(5-9-16)23(30)31/h1-12H,(H,30,31)/b10-3+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324427 ((E)-3-(6-Iodo-2-(4-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-7-10-20-19(13-16)22(28)26(18-3-1-2-15(12-18)23(29)30)21(25-20)11-6-14-4-8-17(9-5-14)27(31)32/h1-13H,(H,29,30)/b11-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324380 ((E)-4-(2-(3-methoxystyryl)-4-oxoquinazolin-3(4H)-y...) Show SMILES COc1cccc(\C=C\c2nc3ccccc3c(=O)n2-c2ccc(cc2)C(O)=O)c1 Show InChI InChI=1S/C24H18N2O4/c1-30-19-6-4-5-16(15-19)9-14-22-25-21-8-3-2-7-20(21)23(27)26(22)18-12-10-17(11-13-18)24(28)29/h2-15H,1H3,(H,28,29)/b14-9+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324428 ((E)-3-(6-Iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H14IN3O5/c24-16-8-9-20-19(13-16)22(28)26(17-5-2-4-15(12-17)23(29)30)21(25-20)10-7-14-3-1-6-18(11-14)27(31)32/h1-13H,(H,29,30)/b10-7+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324461 ((E)-4-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-6-2-3-7-19(18)24-21(14-11-15-5-1-4-8-20(15)26(30)31)25(22)17-12-9-16(10-13-17)23(28)29/h1-14H,(H,28,29)/b14-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324405 ((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324404 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H19N3O5/c33-28-25-18-22(20-6-2-1-3-7-20)12-15-26(25)30-27(16-9-19-5-4-8-24(17-19)32(36)37)31(28)23-13-10-21(11-14-23)29(34)35/h1-18H,(H,34,35)/b16-9+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324459 ((E)-4-(2-(3-Nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-19-6-1-2-7-20(19)24-21(13-8-15-4-3-5-18(14-15)26(30)31)25(22)17-11-9-16(10-12-17)23(28)29/h1-14H,(H,28,29)/b13-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324383 ((E)-4-(4-oxo-2-(3-(trifluoromethyl)styryl)quinazol...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)C(F)(F)F)nc2ccccc2c1=O Show InChI InChI=1S/C24H15F3N2O3/c25-24(26,27)17-5-3-4-15(14-17)8-13-21-28-20-7-2-1-6-19(20)22(30)29(21)18-11-9-16(10-12-18)23(31)32/h1-14H,(H,31,32)/b13-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324394 ((E)-4-(8-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2c(Cl)cccc2c1=O Show InChI InChI=1S/C23H14ClN3O5/c24-19-6-2-5-18-21(19)25-20(12-7-14-3-1-4-17(13-14)27(31)32)26(22(18)28)16-10-8-15(9-11-16)23(29)30/h1-13H,(H,29,30)/b12-7+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324400 ((E)-4-(6-Methyl-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES Cc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O5/c1-15-5-11-21-20(13-15)23(28)26(18-9-7-17(8-10-18)24(29)30)22(25-21)12-6-16-3-2-4-19(14-16)27(31)32/h2-14H,1H3,(H,29,30)/b12-6+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324392 ((E)-4-(6-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Cl)cc2c1=O Show InChI InChI=1S/C23H14ClN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50324398 ((E)-4-(6-Bromo-2-(3-nitrostyryl)-4-oxoquinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Br)cc2c1=O Show InChI InChI=1S/C23H14BrN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50324383 ((E)-4-(4-oxo-2-(3-(trifluoromethyl)styryl)quinazol...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)C(F)(F)F)nc2ccccc2c1=O Show InChI InChI=1S/C24H15F3N2O3/c25-24(26,27)17-5-3-4-15(14-17)8-13-21-28-20-7-2-1-6-19(20)22(30)29(21)18-11-9-16(10-12-18)23(31)32/h1-14H,(H,31,32)/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324433 ((E)-4-(6-Iodo-4-oxo-2-styrylquinazolin-3(4H)-yl)be...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2)nc2ccc(I)cc2c1=O Show InChI InChI=1S/C23H15IN2O3/c24-17-9-12-20-19(14-17)22(27)26(18-10-7-16(8-11-18)23(28)29)21(25-20)13-6-15-4-2-1-3-5-15/h1-14H,(H,28,29)/b13-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324429 ((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-11-12-21-20(14-19)23(28)26(17-9-5-16(6-10-17)24(29)30)22(25-21)13-4-15-2-7-18(8-3-15)27(31)32/h2-14H,1H3,(H,29,30)/b13-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50324436 ((E)-4-(2-(2-(naphthalen-2-yl)vinyl)-4-oxoquinazoli...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc3ccccc3c2)nc2ccccc2c1=O Show InChI InChI=1S/C27H18N2O3/c30-26-23-7-3-4-8-24(23)28-25(29(26)22-14-12-20(13-15-22)27(31)32)16-10-18-9-11-19-5-1-2-6-21(19)17-18/h1-17H,(H,31,32)/b16-10+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair

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