Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'ao' and Initial = 'gz'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50140241 (Allopurinol | Aloral | Aluline 100 | Aluline 300 |...) Show SMILES O=c1[nH]cnc2[nH]ncc12 Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50424969 (CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Br)cc3)C2=O)c1 Show InChI InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50424957 (CHEMBL2316158 | US9409845, Table 1, Compound 19: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)S(C)(=O)=O)C2=O)c1 Show InChI InChI=1S/C23H24O5S/c1-27-20-13-17(14-21(15-20)28-2)12-19-6-4-5-18(23(19)24)11-16-7-9-22(10-8-16)29(3,25)26/h7-15H,4-6H2,1-3H3/b18-11+,19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50204606 (CHEMBL3933132) Show SMILES COc1cc(OC)cc(\C=C2/CC\C(=C/c3ccc(cc3)S(C)(=O)=O)C2=O)c1 Show InChI InChI=1S/C22H22O5S/c1-26-19-12-16(13-20(14-19)27-2)11-18-7-6-17(22(18)23)10-15-4-8-21(9-5-15)28(3,24)25/h4-5,8-14H,6-7H2,1-3H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50424970 (CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Br)c3)C2=O)c1 Show InChI InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50424973 (CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3Cl)C2=O)c1 Show InChI InChI=1S/C22H21ClO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50204607 (CHEMBL3960045) Show SMILES COc1cc(OC)cc(\C=C2/CC\C(=C/c3cccc(Cl)c3)C2=O)c1 Show InChI InChI=1S/C21H19ClO3/c1-24-19-11-15(12-20(13-19)25-2)9-17-7-6-16(21(17)23)8-14-4-3-5-18(22)10-14/h3-5,8-13H,6-7H2,1-2H3/b16-8+,17-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5446 (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50204608 (CHEMBL3971115) Show SMILES COc1cc(OC)cc(\C=C2/CC\C(=C/c3cccc(Br)c3)C2=O)c1 Show InChI InChI=1S/C21H19BrO3/c1-24-19-11-15(12-20(13-19)25-2)9-17-7-6-16(21(17)23)8-14-4-3-5-18(22)10-14/h3-5,8-13H,6-7H2,1-2H3/b16-8+,17-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50204605 (CHEMBL3941517) Show SMILES COc1cc(OC)cc(\C=C2/CC\C(=C/c3ccccc3Cl)C2=O)c1 Show InChI InChI=1S/C21H19ClO3/c1-24-18-10-14(11-19(13-18)25-2)9-16-7-8-17(21(16)23)12-15-5-3-4-6-20(15)22/h3-6,9-13H,7-8H2,1-2H3/b16-9+,17-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50424974 (CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Cl)c3)C2=O)c1 Show InChI InChI=1S/C22H21ClO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...				Bioorg Med Chem 25: 166-174 (2017) Article DOI: 10.1016/j.bmc.2016.10.022 BindingDB Entry DOI: 10.7270/Q2W37Z90
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424964 (CHEMBL2316151 | US9409845, Table 1, Compound 12: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(O)c(O)c3)C2=O)c1 Show InChI InChI=1S/C22H22O5/c1-26-18-10-15(11-19(13-18)27-2)9-17-5-3-4-16(22(17)25)8-14-6-7-20(23)21(24)12-14/h6-13,23-24H,3-5H2,1-2H3/b16-8+,17-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424973 (CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3Cl)C2=O)c1 Show InChI InChI=1S/C22H21ClO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424975 (CHEMBL2316140 | US9409845, Table 1, Compound 1: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3)C2=O)c1 Show InChI InChI=1S/C22H22O3/c1-24-20-13-17(14-21(15-20)25-2)12-19-10-6-9-18(22(19)23)11-16-7-4-3-5-8-16/h3-5,7-8,11-15H,6,9-10H2,1-2H3/b18-11+,19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424957 (CHEMBL2316158 | US9409845, Table 1, Compound 19: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)S(C)(=O)=O)C2=O)c1 Show InChI InChI=1S/C23H24O5S/c1-27-20-13-17(14-21(15-20)28-2)12-19-6-4-5-18(23(19)24)11-16-7-9-22(10-8-16)29(3,25)26/h7-15H,4-6H2,1-3H3/b18-11+,19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424958 (CHEMBL2316157 | US9409845, Table 1, Compound 18: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cc(OC)cc(OC)c3)C2=O)c1 Show InChI InChI=1S/C24H26O5/c1-26-20-10-16(11-21(14-20)27-2)8-18-6-5-7-19(24(18)25)9-17-12-22(28-3)15-23(13-17)29-4/h8-15H,5-7H2,1-4H3/b18-8+,19-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424972 (CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3F)C2=O)c1 Show InChI InChI=1S/C22H21FO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424974 (CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Cl)c3)C2=O)c1 Show InChI InChI=1S/C22H21ClO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424961 (CHEMBL2316154 | US9409845, Table 1, Compound 15: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(cc3)N(C)C)C2=O)c1 Show InChI InChI=1S/C24H27NO3/c1-25(2)21-10-8-17(9-11-21)12-19-6-5-7-20(24(19)26)13-18-14-22(27-3)16-23(15-18)28-4/h8-16H,5-7H2,1-4H3/b19-12+,20-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424962 (CHEMBL2316153 | US9409845, Table 1, Compound 14: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(O)cc3)C2=O)c1 Show InChI InChI=1S/C22H22O4/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14,23H,3-5H2,1-2H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424956 (CHEMBL2316159 | US9409845, Table 1, Compound 20: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)C2=O)c1 Show InChI InChI=1S/C30H38O4/c1-29(2,3)25-16-20(17-26(28(25)32)30(4,5)6)13-22-11-9-10-21(27(22)31)12-19-14-23(33-7)18-24(15-19)34-8/h12-18,32H,9-11H2,1-8H3/b21-12+,22-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424960 (CHEMBL2316155 | US9409845, Table 1, Compound 16: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(OC)c(O)c3)C2=O)c1 Show InChI InChI=1S/C23H24O5/c1-26-19-11-16(12-20(14-19)27-2)10-18-6-4-5-17(23(18)25)9-15-7-8-22(28-3)21(24)13-15/h7-14,24H,4-6H2,1-3H3/b17-9+,18-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424968 (CHEMBL2316147 | US9409845, Table 1, Compound 8: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(F)cc3)C2=O)c1 Show InChI InChI=1S/C22H21FO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424965 (CHEMBL2316150 | US9409845, Table 1, Compound 11: (...) Show SMILES COc1cccc(\C=C2/CCC\C(=C/c3cc(OC)cc(OC)c3)C2=O)c1 Show InChI InChI=1S/C23H24O4/c1-25-20-9-4-6-16(12-20)10-18-7-5-8-19(23(18)24)11-17-13-21(26-2)15-22(14-17)27-3/h4,6,9-15H,5,7-8H2,1-3H3/b18-10+,19-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424970 (CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3cccc(Br)c3)C2=O)c1 Show InChI InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)10-18-7-4-6-17(22(18)24)9-15-5-3-8-19(23)11-15/h3,5,8-14H,4,6-7H2,1-2H3/b17-9+,18-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424969 (CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Br)cc3)C2=O)c1 Show InChI InChI=1S/C22H21BrO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424966 (CHEMBL2316149 | US9409845, Table 1, Compound 10: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/C3CCCCC3)C2=O)c1 Show InChI InChI=1S/C22H28O3/c1-24-20-13-17(14-21(15-20)25-2)12-19-10-6-9-18(22(19)23)11-16-7-4-3-5-8-16/h11-16H,3-10H2,1-2H3/b18-11+,19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424971 (CHEMBL2316144 | US9409845, Table 1, Compound 5: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3Br)C2=O)c1 Show InChI InChI=1S/C22H21BrO3/c1-25-19-11-15(12-20(14-19)26-2)10-17-7-5-8-18(22(17)24)13-16-6-3-4-9-21(16)23/h3-4,6,9-14H,5,7-8H2,1-2H3/b17-10+,18-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50067040 (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O |w:12.11,5.4| Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424967 (CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Cl)cc3)C2=O)c1 Show InChI InChI=1S/C22H21ClO3/c1-25-20-12-16(13-21(14-20)26-2)11-18-5-3-4-17(22(18)24)10-15-6-8-19(23)9-7-15/h6-14H,3-5H2,1-2H3/b17-10+,18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424959 (CHEMBL2316156) Show SMILES COc1ccc(\C=C2/CCC\C(=C/c3cc(OC)cc(OC)c3)C2=O)cc1 Show InChI InChI=1S/C23H24O4/c1-25-20-9-7-16(8-10-20)11-18-5-4-6-19(23(18)24)12-17-13-21(26-2)15-22(14-17)27-3/h7-15H,4-6H2,1-3H3/b18-11+,19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424963 (CHEMBL2316152 | US9409845, Table 1, Compound 13: (...) Show SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3OC)C2=O)c1 Show InChI InChI=1S/C23H24O4/c1-25-20-12-16(13-21(15-20)26-2)11-18-8-6-9-19(23(18)24)14-17-7-4-5-10-22(17)27-3/h4-5,7,10-15H,6,8-9H2,1-3H3/b18-11+,19-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
					More data for this Ligand-Target Pair