BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50424960'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424960 (CHEMBL2316155 \| US9409845, Table 1, Compound 16: (...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...				Bioorg Med Chem 21: 388-94 (2012) Article DOI: 10.1016/j.bmc.2012.11.031 BindingDB Entry DOI: 10.7270/Q2SJ1MX6
Soochow University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50424960 (CHEMBL2316155 \| US9409845, Table 1, Compound 16: (...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.37E+3	n/a	n/a	n/a	n/a	n/a	25
PHARMAXYN LABORATORIES LTD. US Patent					Assay Description The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...				US Patent US9409845 (2016) BindingDB Entry DOI: 10.7270/Q25M64MC
PHARMAXYN LABORATORIES LTD. US Patent					More data for this Ligand-Target Pair