Compile Data Set for Download or QSAR

Found 4095 hits with Last Name = 'arora' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50040728 (CHEMBL3353219 | US9255110, 1) Show SMILES NCC1CCN(CC1)c1ccc(Cl)cc1NC(=O)c1cnn2cc(O)cnc12 Show InChI InChI=1S/C19H21ClN6O2/c20-13-1-2-17(25-5-3-12(8-21)4-6-25)16(7-13)24-19(28)15-10-23-26-11-14(27)9-22-18(15)26/h1-2,7,9-12,27H,3-6,8,21H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM206090 (US9255110, 2) Show SMILES NCC1CCN(CC1)c1cc2ncccc2cc1NC(=O)c1cnn2cccnc12 Show InChI InChI=1S/C22H23N7O/c23-13-15-4-9-28(10-5-15)20-12-18-16(3-1-6-24-18)11-19(20)27-22(30)17-14-26-29-8-2-7-25-21(17)29/h1-3,6-8,11-12,14-15H,4-5,9-10,13,23H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485457 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5-phen...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485457 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5-phen...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485461 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5- phe...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ncc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485461 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5- phe...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ncc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM206091 (US9255110, 3) Show SMILES COc1cc2nc(NCCO)ccc2cc1NC(=O)c1cnn2cccnc12 Show InChI InChI=1S/C19H18N6O3/c1-28-16-10-14-12(3-4-17(23-14)20-6-8-26)9-15(16)24-19(27)13-11-22-25-7-2-5-21-18(13)25/h2-5,7,9-11,26H,6,8H2,1H3,(H,20,23)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485467 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*S)-(2-methy...) Show SMILES Cc1nc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:25.26,30.33,(-3.32,.46,;-3.32,2,;-4.65,2.77,;-4.65,4.31,;-5.98,5.08,;-7.32,4.31,;-8.65,5.08,;-9.98,4.31,;-9.98,2.77,;-8.65,2,;-7.32,2.77,;-3.32,5.08,;-1.98,4.31,;-1.98,2.77,;-.65,2,;-.65,.46,;-1.98,-.31,;-1.98,-1.85,;-.65,-2.62,;.68,-1.85,;2.15,-2.33,;3.05,-1.08,;4.59,-1.08,;5.36,-2.41,;5.36,.25,;6.9,.25,;7.67,1.59,;9.21,1.59,;9.98,.25,;9.21,-1.08,;7.67,-1.08,;6.9,-2.41,;7.67,-3.75,;6.9,-5.08,;9.21,-3.75,;9.98,-2.41,;2.02,.46,;2.02,2,;.68,2.77,;.68,4.31,;.68,-.31,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK [386-659] (Homo sapiens (Human))	BDBM467351 (N-((3R,5S)-1-Acryloyl-5-hydroxypiperidin-3-yl)-5-(...) Show SMILES Cc1cc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4C[C@@H](O)CN(C4)C(=O)C=C)c([nH]c1=O)c23 |r,wU:27.29,wD:25.26,(-1.73,4.27,;-3.06,3.5,;-4.4,4.27,;-5.73,3.5,;-7.06,4.27,;-8.4,3.5,;-8.4,1.96,;-9.73,1.19,;-11.07,1.96,;-11.07,3.5,;-9.73,4.27,;-5.73,1.96,;-4.4,1.19,;-3.06,1.96,;-1.73,1.19,;-1.73,-.35,;-3.06,-1.12,;-3.06,-2.66,;-1.73,-3.43,;-.4,-2.66,;1.09,-3.06,;1.92,-1.6,;3.4,-1.6,;4.17,-2.94,;4.17,-.27,;5.67,-.27,;6.44,1.06,;7.98,1.06,;8.76,2.4,;8.76,-.27,;7.98,-1.6,;6.44,-1.6,;8.76,-2.94,;7.98,-4.27,;10.3,-2.94,;11.07,-1.6,;.94,-.35,;.94,1.19,;-.4,1.96,;-.4,3.5,;-.4,-1.12,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10822348 (2020) BindingDB Entry DOI: 10.7270/Q22V2K6B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485467 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*S)-(2-methy...) Show SMILES Cc1nc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:25.26,30.33,(-3.32,.46,;-3.32,2,;-4.65,2.77,;-4.65,4.31,;-5.98,5.08,;-7.32,4.31,;-8.65,5.08,;-9.98,4.31,;-9.98,2.77,;-8.65,2,;-7.32,2.77,;-3.32,5.08,;-1.98,4.31,;-1.98,2.77,;-.65,2,;-.65,.46,;-1.98,-.31,;-1.98,-1.85,;-.65,-2.62,;.68,-1.85,;2.15,-2.33,;3.05,-1.08,;4.59,-1.08,;5.36,-2.41,;5.36,.25,;6.9,.25,;7.67,1.59,;9.21,1.59,;9.98,.25,;9.21,-1.08,;7.67,-1.08,;6.9,-2.41,;7.67,-3.75,;6.9,-5.08,;9.21,-3.75,;9.98,-2.41,;2.02,.46,;2.02,2,;.68,2.77,;.68,4.31,;.68,-.31,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM467822 (N-((3R,5R)-1-Acryloyl-5-hydroxypiperidin-3-yl)-5-(...) Show SMILES Cc1cc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4C[C@@H](O)CN(C4)C(=O)C=C)c([nH]c1=O)c23 |r,wU:27.29,wD:25.26,(-1.78,4.35,;-3.12,3.58,;-4.45,4.35,;-5.78,3.58,;-7.12,4.35,;-8.45,3.58,;-9.78,4.35,;-11.12,3.58,;-11.12,2.04,;-9.78,1.27,;-8.45,2.04,;-5.78,2.04,;-4.45,1.27,;-3.12,2.04,;-1.78,1.27,;-1.78,-.27,;-3.12,-1.04,;-3.12,-2.58,;-1.78,-3.35,;-.45,-2.58,;1.04,-2.98,;1.88,-1.68,;3.42,-1.68,;4.19,-3.02,;4.19,-.35,;5.73,-.35,;6.5,.98,;8.04,.98,;8.81,2.32,;8.81,-.35,;8.04,-1.68,;6.5,-1.68,;8.81,-3.02,;8.04,-4.35,;10.35,-3.02,;11.12,-1.68,;.89,-.27,;.89,1.27,;-.45,2.04,;-.45,3.58,;-.45,-1.04,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description TBD				US Patent US10800792 (2020) BindingDB Entry DOI: 10.7270/Q2N019K7
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM206092 (US9255110, 4) Show SMILES NCC1CCN(CC1)c1cc(ccc1NC(=O)c1cnn2cccnc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H27N7O2/c27-16-18-9-13-32(14-10-18)23-15-19(25(34)30-20-5-2-1-3-6-20)7-8-22(23)31-26(35)21-17-29-33-12-4-11-28-24(21)33/h1-8,11-12,15,17-18H,9-10,13-14,16,27H2,(H,30,34)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485459 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5-phen...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4cnc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.07	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485460 (N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(5- ph...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ncc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.07	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485461 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(5- phe...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ncc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485460 (N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(5- ph...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ncc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485600 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-(py...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccn5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485458 (N-((1RS,2RS)-2-Acrylamidocyclopentyl)-5-(2-methyl-...) Show SMILES C=CC(=O)N[C@@H]1CCC(C1)NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485458 (N-((1RS,2RS)-2-Acrylamidocyclopentyl)-5-(2-methyl-...) Show SMILES C=CC(=O)N[C@@H]1CCC(C1)NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485600 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(4-(py...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccn5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485345 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485345 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485270 (N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(4-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485270 (N-((1R,2S)-2-acrylamidocyclopentyl)-4-oxo-5-(4-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485338 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(6-phen...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485338 (N-((1R,2S)-2-Acrylamidocyclohexyl)-4-oxo-5-(6-phen...) Show SMILES C=CC(=O)N[C@H]1CCCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485333 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4cc(ncn4)-c4ccccc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485333 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4cc(ncn4)-c4ccccc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485367 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4cnc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485367 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(5-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4cnc(Oc5ccccc5)cn4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM206093 (US9255110, 5) Show SMILES CC(O)C1CCN(CC1)c1ccc(Cl)cc1NC(=O)c1cnn2cccnc12 Show InChI InChI=1S/C20H22ClN5O2/c1-13(27)14-5-9-25(10-6-14)18-4-3-15(21)11-17(18)24-20(28)16-12-23-26-8-2-7-22-19(16)26/h2-4,7-8,11-14,27H,5-6,9-10H2,1H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM468112 ((R)-N-(1-Acryloylpiperidin-3-yl)-5-(5-(2-fluorophe...) Show SMILES Fc1ccccc1Oc1ccc(nc1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCCN(C4)C(=O)C=C)c([nH]c1=O)c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description TBD				US Patent US10800792 (2020) BindingDB Entry DOI: 10.7270/Q2N019K7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485331 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*R)-(4-isop...) Show SMILES CC(C)Oc1ccc(c(C)c1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:22.22,26.28,(-9.26,6.86,;-7.93,6.09,;-7.93,4.55,;-6.6,6.86,;-5.26,6.09,;-5.26,4.55,;-3.93,3.78,;-2.59,4.55,;-2.59,6.09,;-1.26,6.86,;-3.93,6.86,;-1.26,3.78,;-1.26,2.24,;-2.59,1.47,;-2.59,-.07,;-1.26,-.84,;.07,-.07,;1.56,-.46,;2.33,.87,;3.87,.87,;4.64,2.2,;4.64,-.46,;6.18,-.46,;7.09,.78,;8.55,.3,;8.55,-1.23,;7.09,-1.71,;6.69,-3.2,;7.78,-4.29,;9.26,-3.89,;7.38,-5.77,;8.47,-6.86,;1.41,2.24,;1.41,3.78,;.07,4.55,;.07,6.09,;.07,1.47,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM467999 ((R)-N-(1-Acryloylpiperidin-3-yl)-5-(R)-(2-methyl-6...) Show SMILES Cc1nc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCN(C4)C(=O)C=C)c([nH]c1=O)c23 |r,wU:25.26,(-4.48,-.77,;-4.48,.77,;-5.82,1.54,;-5.82,3.08,;-7.15,3.85,;-8.48,3.08,;-9.82,3.85,;-11.15,3.08,;-11.15,1.54,;-9.82,.77,;-8.48,1.54,;-4.48,3.85,;-3.15,3.08,;-3.15,1.54,;-1.82,.77,;-1.82,-.77,;-3.15,-1.54,;-3.15,-3.08,;-1.82,-3.85,;-.48,-3.08,;1.01,-3.48,;1.94,-1.86,;3.48,-1.86,;4.25,-3.19,;4.25,-.53,;5.79,-.53,;6.56,-1.86,;8.1,-1.86,;8.87,-.53,;8.1,.81,;6.56,.81,;8.87,2.14,;8.1,3.48,;10.41,2.14,;11.15,3.43,;.85,-.77,;.85,.77,;-.48,1.54,;-.48,3.08,;-.48,-1.54,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description TBD				US Patent US10800792 (2020) BindingDB Entry DOI: 10.7270/Q2N019K7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485331 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*R)-(4-isop...) Show SMILES CC(C)Oc1ccc(c(C)c1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:22.22,26.28,(-9.26,6.86,;-7.93,6.09,;-7.93,4.55,;-6.6,6.86,;-5.26,6.09,;-5.26,4.55,;-3.93,3.78,;-2.59,4.55,;-2.59,6.09,;-1.26,6.86,;-3.93,6.86,;-1.26,3.78,;-1.26,2.24,;-2.59,1.47,;-2.59,-.07,;-1.26,-.84,;.07,-.07,;1.56,-.46,;2.33,.87,;3.87,.87,;4.64,2.2,;4.64,-.46,;6.18,-.46,;7.09,.78,;8.55,.3,;8.55,-1.23,;7.09,-1.71,;6.69,-3.2,;7.78,-4.29,;9.26,-3.89,;7.38,-5.77,;8.47,-6.86,;1.41,2.24,;1.41,3.78,;.07,4.55,;.07,6.09,;.07,1.47,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK [386-659] (Homo sapiens (Human))	BDBM468112 ((R)-N-(1-Acryloylpiperidin-3-yl)-5-(5-(2-fluorophe...) Show SMILES Fc1ccccc1Oc1ccc(nc1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCCN(C4)C(=O)C=C)c([nH]c1=O)c23 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10822348 (2020) BindingDB Entry DOI: 10.7270/Q22V2K6B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK [386-659] (Homo sapiens (Human))	BDBM467359 ((R)-N-(1-Acryloylpiperidin-3-yl)-5-(2-fluoro-4-phe...) Show SMILES Cc1nc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCN(C4)C(=O)C=C)c([nH]c1=O)c23 |r,wD:25.26,(-4.14,.21,;-4.14,1.75,;-5.47,2.52,;-5.47,4.06,;-6.81,4.83,;-8.14,4.06,;-8.14,2.52,;-9.48,1.75,;-10.81,2.52,;-10.81,4.06,;-9.48,4.83,;-4.14,4.83,;-2.81,4.06,;-2.81,2.52,;-1.47,1.75,;-1.47,.21,;-2.81,-.56,;-2.81,-2.1,;-1.47,-2.87,;-.14,-2.1,;1.35,-2.5,;2.34,-.82,;3.88,-.82,;4.65,-2.16,;4.65,.51,;6.19,.51,;6.96,1.84,;8.5,1.84,;9.27,.51,;8.5,-.82,;6.96,-.82,;9.27,-2.16,;10.81,-2.16,;8.5,-3.49,;9.27,-4.83,;1.19,.21,;1.19,1.75,;-.14,2.52,;-.14,4.06,;-.14,-.56,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10822348 (2020) BindingDB Entry DOI: 10.7270/Q22V2K6B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485387 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*S)-(6-cyclo...) Show SMILES Cc1cc(OC2CCC2)ncc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:28.31,23.24,(-1.07,6.19,;-2.4,5.42,;-3.73,6.19,;-5.07,5.42,;-6.4,6.19,;-7.73,5.42,;-9.22,5.82,;-9.62,4.33,;-8.13,3.93,;-5.07,3.88,;-3.73,3.11,;-2.4,3.88,;-1.07,3.11,;-1.07,1.57,;-2.4,.8,;-2.4,-.74,;-1.07,-1.51,;.27,-.74,;1.76,-1.14,;2.69,.48,;4.23,.48,;5,1.81,;5,-.85,;6.54,-.85,;7.31,.48,;8.85,.48,;9.62,-.85,;8.85,-2.19,;7.31,-2.19,;6.54,-3.52,;7.31,-4.86,;6.54,-6.19,;8.85,-4.86,;9.62,-3.52,;1.6,1.57,;1.6,3.11,;.27,3.88,;.27,5.42,;.27,.8,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.13	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485349 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(6-cyclobutox...) Show SMILES Cc1cc(OC2CCC2)ncc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:23.24,28.31,(-1.03,6.4,;-2.36,5.63,;-3.7,6.4,;-5.03,5.63,;-6.36,6.4,;-7.7,5.63,;-9.18,6.02,;-9.58,4.54,;-8.1,4.14,;-5.03,4.09,;-3.7,3.32,;-2.36,4.09,;-1.03,3.32,;-1.03,1.78,;-2.34,1.04,;-2.34,-.49,;-1.03,-1.23,;.31,-.49,;1.76,-.96,;2.65,.27,;4.19,.27,;4.96,1.61,;4.96,-1.06,;6.5,-1.06,;7.27,.27,;8.81,.27,;9.58,-1.06,;8.81,-2.4,;7.27,-2.4,;6.5,-3.73,;7.27,-5.06,;6.5,-6.4,;8.81,-5.06,;9.58,-3.73,;1.62,1.79,;1.64,3.32,;.31,4.09,;.31,5.63,;.31,1.04,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485344 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485340 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*R)-(4-isopr...) Show SMILES CC(C)Oc1ccc(c(C)c1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wU:22.22,27.29,(-9.32,3.6,;-7.98,2.83,;-7.98,1.29,;-6.65,3.6,;-5.32,2.83,;-5.32,1.29,;-3.98,.52,;-2.65,1.29,;-2.65,2.83,;-1.32,3.6,;-3.98,3.6,;-1.32,.52,;-1.32,-1.02,;-2.65,-1.79,;-2.65,-3.33,;-1.32,-4.1,;.02,-3.33,;1.48,-3.81,;2.39,-2.56,;3.93,-2.56,;4.7,-3.9,;4.7,-1.23,;6.24,-1.23,;7.01,-2.56,;8.55,-2.56,;9.32,-1.23,;8.55,.1,;7.01,.1,;6.24,1.44,;7.01,2.77,;6.24,4.1,;8.55,2.77,;9.32,1.44,;1.35,-1.02,;1.35,.52,;.02,1.29,;.02,2.83,;.02,-1.79,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485344 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(6-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5ccccc5)nc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485340 (N-((1R,2S)-2-Acrylamidocyclohexyl)-5-(*R)-(4-isopr...) Show SMILES CC(C)Oc1ccc(c(C)c1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wU:22.22,27.29,(-9.32,3.6,;-7.98,2.83,;-7.98,1.29,;-6.65,3.6,;-5.32,2.83,;-5.32,1.29,;-3.98,.52,;-2.65,1.29,;-2.65,2.83,;-1.32,3.6,;-3.98,3.6,;-1.32,.52,;-1.32,-1.02,;-2.65,-1.79,;-2.65,-3.33,;-1.32,-4.1,;.02,-3.33,;1.48,-3.81,;2.39,-2.56,;3.93,-2.56,;4.7,-3.9,;4.7,-1.23,;6.24,-1.23,;7.01,-2.56,;8.55,-2.56,;9.32,-1.23,;8.55,.1,;7.01,.1,;6.24,1.44,;7.01,2.77,;6.24,4.1,;8.55,2.77,;9.32,1.44,;1.35,-1.02,;1.35,.52,;.02,1.29,;.02,2.83,;.02,-1.79,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485464 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(*S)-(...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5cccnc5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.37	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485464 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(*S)-(...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccc(Oc5cccnc5)cc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485335 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(2-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccnc(c4)-c4ccccc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485335 (N-((1R,2S)-2-Acrylamidocyclopentyl)-4-oxo-5-(2-phe...) Show SMILES C=CC(=O)N[C@H]1CCC[C@H]1NC(=O)c1sc2nccc3n(-c4ccnc(c4)-c4ccccc4)c(=O)[nH]c1c23 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485273 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(2-meth...) Show SMILES Cc1cc(Oc2ccccc2)ccc1-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wU:25.26,29.32,(-.48,2.9,;-1.82,2.13,;-3.15,2.9,;-4.48,2.13,;-5.82,2.9,;-7.15,2.13,;-8.49,2.9,;-9.82,2.13,;-9.82,.59,;-8.49,-.18,;-7.15,.59,;-4.48,.59,;-3.15,-.18,;-1.82,.59,;-.48,-.18,;-.48,-1.72,;-1.82,-2.49,;-1.82,-4.03,;-.48,-4.8,;.85,-4.03,;2.3,-4.48,;3,-3,;4.54,-3,;5.31,-4.33,;5.31,-1.66,;6.85,-1.66,;7.76,-2.91,;9.22,-2.43,;9.22,-.89,;7.76,-.42,;7.28,1.05,;8.31,2.19,;9.82,1.87,;7.84,3.66,;8.87,4.8,;2.18,-1.72,;2.18,-.18,;.85,.59,;.85,2.13,;.85,-2.49,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485536 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isob...) Show SMILES CC(C)COc1cc(C)c(cn1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:23.23,27.29,(-10,4.9,;-8.75,5.8,;-8.91,7.33,;-7.34,5.18,;-6.01,5.95,;-4.68,5.18,;-3.34,5.95,;-2.01,5.18,;-.68,5.95,;-2.01,3.64,;-3.34,2.87,;-4.68,3.64,;-.51,2.84,;-.51,1.3,;-1.84,.53,;-1.83,-1.01,;-.5,-1.78,;.83,-1.01,;2.32,-1.4,;3.25,.02,;4.9,-.01,;5.83,1.22,;5.43,-1.82,;7.01,-1.85,;8.09,-.75,;9.47,-1.45,;9.24,-2.97,;7.72,-3.22,;6.69,-4.57,;7.49,-5.88,;6.97,-7.33,;9,-5.61,;10,-6.79,;2.16,1.31,;2.15,2.85,;.82,3.61,;.81,5.15,;.83,.53,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485536 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isob...) Show SMILES CC(C)COc1cc(C)c(cn1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:23.23,27.29,(-10,4.9,;-8.75,5.8,;-8.91,7.33,;-7.34,5.18,;-6.01,5.95,;-4.68,5.18,;-3.34,5.95,;-2.01,5.18,;-.68,5.95,;-2.01,3.64,;-3.34,2.87,;-4.68,3.64,;-.51,2.84,;-.51,1.3,;-1.84,.53,;-1.83,-1.01,;-.5,-1.78,;.83,-1.01,;2.32,-1.4,;3.25,.02,;4.9,-.01,;5.83,1.22,;5.43,-1.82,;7.01,-1.85,;8.09,-.75,;9.47,-1.45,;9.24,-2.97,;7.72,-3.22,;6.69,-4.57,;7.49,-5.88,;6.97,-7.33,;9,-5.61,;10,-6.79,;2.16,1.31,;2.15,2.85,;.82,3.61,;.81,5.15,;.83,.53,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair

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