Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM485536'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485536 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isob...) Show SMILES CC(C)COc1cc(C)c(cn1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:23.23,27.29,(-10,4.9,;-8.75,5.8,;-8.91,7.33,;-7.34,5.18,;-6.01,5.95,;-4.68,5.18,;-3.34,5.95,;-2.01,5.18,;-.68,5.95,;-2.01,3.64,;-3.34,2.87,;-4.68,3.64,;-.51,2.84,;-.51,1.3,;-1.84,.53,;-1.83,-1.01,;-.5,-1.78,;.83,-1.01,;2.32,-1.4,;3.25,.02,;4.9,-.01,;5.83,1.22,;5.43,-1.82,;7.01,-1.85,;8.09,-.75,;9.47,-1.45,;9.24,-2.97,;7.72,-3.22,;6.69,-4.57,;7.49,-5.88,;6.97,-7.33,;9,-5.61,;10,-6.79,;2.16,1.31,;2.15,2.85,;.82,3.61,;.81,5.15,;.83,.53,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2F55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM485536 (N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(6-isob...) Show SMILES CC(C)COc1cc(C)c(cn1)-n1c2ccnc3sc(C(=O)N[C@@H]4CCC[C@@H]4NC(=O)C=C)c([nH]c1=O)c23 |r,wD:23.23,27.29,(-10,4.9,;-8.75,5.8,;-8.91,7.33,;-7.34,5.18,;-6.01,5.95,;-4.68,5.18,;-3.34,5.95,;-2.01,5.18,;-.68,5.95,;-2.01,3.64,;-3.34,2.87,;-4.68,3.64,;-.51,2.84,;-.51,1.3,;-1.84,.53,;-1.83,-1.01,;-.5,-1.78,;.83,-1.01,;2.32,-1.4,;3.25,.02,;4.9,-.01,;5.83,1.22,;5.43,-1.82,;7.01,-1.85,;8.09,-.75,;9.47,-1.45,;9.24,-2.97,;7.72,-3.22,;6.69,-4.57,;7.49,-5.88,;6.97,-7.33,;9,-5.61,;10,-6.79,;2.16,1.31,;2.15,2.85,;.82,3.61,;.81,5.15,;.83,.53,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...				US Patent US10934310 (2021) BindingDB Entry DOI: 10.7270/Q2FT8Q4F
					More data for this Ligand-Target Pair