Compile Data Set for Download or QSAR

Found 127 hits with Last Name = 'ashoor' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004518 (CHEMBL2079256) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-32-29(36)31(25-13-5-3-6-14-25,26-15-7-4-8-16-26)35(30(32)37)20-12-11-19-33-21-23-34(24-22-33)27-17-9-10-18-28(27)38-2/h3-10,13-18H,11-12,19-24H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004756 (CHEMBL3233679) Show SMILES Cl.COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(C2=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C24H29FN4O4.ClH/c1-24(17-7-9-18(25)10-8-17)22(31)29(23(32)26-24)16-19(30)15-27-11-13-28(14-12-27)20-5-3-4-6-21(20)33-2;/h3-10,19,30H,11-16H2,1-2H3,(H,26,32);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004520 (CHEMBL3233401) Show SMILES CCOc1ccccc1N1CCN(CCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-3-38-28-18-11-10-17-27(28)34-23-21-33(22-24-34)19-12-20-35-30(37)32(2)29(36)31(35,25-13-6-4-7-14-25)26-15-8-5-9-16-26/h4-11,13-18H,3,12,19-24H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004517 (CHEMBL1916745) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C30H34N4O3/c1-31-28(35)30(24-12-5-3-6-13-24,25-14-7-4-8-15-25)34(29(31)36)19-11-18-32-20-22-33(23-21-32)26-16-9-10-17-27(26)37-2/h3-10,12-17H,11,18-23H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004521 (CHEMBL3233402) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2)C(C1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N4O2.ClH/c1-32-29(36)31(26-14-6-2-7-15-26,27-16-8-3-9-17-27)35(30(32)37)21-13-5-12-20-33-22-24-34(25-23-33)28-18-10-4-11-19-28;/h2-4,6-11,14-19H,5,12-13,20-25H2,1H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004518 (CHEMBL2079256) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-32-29(36)31(25-13-5-3-6-14-25,26-15-7-4-8-16-26)35(30(32)37)20-12-11-19-33-21-23-34(24-22-33)27-17-9-10-18-28(27)38-2/h3-10,13-18H,11-12,19-24H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004524 (CHEMBL3233667) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 Show InChI InChI=1S/C27H36N4O3.ClH/c1-27(22-12-6-4-7-13-22)25(32)28(2)26(33)31(27)17-11-5-10-16-29-18-20-30(21-19-29)23-14-8-9-15-24(23)34-3;/h4,6-9,12-15H,5,10-11,16-21H2,1-3H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004570 (CHEMBL3233669) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(Cc3ccccc3)C(=O)C2(C)C)CC1 Show InChI InChI=1S/C28H38N4O3.ClH/c1-28(2)26(33)31(22-23-12-6-4-7-13-23)27(34)32(28)17-11-5-10-16-29-18-20-30(21-19-29)24-14-8-9-15-25(24)35-3;/h4,6-9,12-15H,5,10-11,16-22H2,1-3H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004684 (CHEMBL3233676) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-9-10-20(28)17-22(19)30)26(37)35(27)12-5-3-4-11-32-13-15-33(16-14-32)23-8-6-7-21(29)24(23)31;/h6-10,17H,3-5,11-16,18H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004524 (CHEMBL3233667) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 Show InChI InChI=1S/C27H36N4O3.ClH/c1-27(22-12-6-4-7-13-22)25(32)28(2)26(33)31(27)17-11-5-10-16-29-18-20-30(21-19-29)23-14-8-9-15-24(23)34-3;/h4,6-9,12-15H,5,10-11,16-21H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004591 (CHEMBL3233670) Show SMILES Cl.COc1cccc(c1)N1CCN(CCCCCN2C(=O)N(Cc3ccccc3)C(=O)C2(C)C)CC1 Show InChI InChI=1S/C28H38N4O3.ClH/c1-28(2)26(33)31(22-23-11-6-4-7-12-23)27(34)32(28)16-9-5-8-15-29-17-19-30(20-18-29)24-13-10-14-25(21-24)35-3;/h4,6-7,10-14,21H,5,8-9,15-20,22H2,1-3H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004655 (CHEMBL3233672) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-9-5-3-6-10-22)26(34)32(27)16-8-4-7-15-29-17-19-30(20-18-29)24-13-11-23(28)12-14-24;/h3,5-6,9-14H,4,7-8,15-21H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004683 (CHEMBL3233675) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H34F2N4O2.ClH/c1-27(2)25(34)32(20-21-6-8-22(28)9-7-21)26(35)33(27)15-5-3-4-14-30-16-18-31(19-17-30)24-12-10-23(29)11-13-24;/h6-13H,3-5,14-20H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004525 (CHEMBL3233668) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccccc2)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H36N4O2.ClH/c1-27(2)25(32)30(22-23-12-6-3-7-13-23)26(33)31(27)17-11-5-10-16-28-18-20-29(21-19-28)24-14-8-4-9-15-24;/h3-4,6-9,12-15H,5,10-11,16-22H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004570 (CHEMBL3233669) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(Cc3ccccc3)C(=O)C2(C)C)CC1 Show InChI InChI=1S/C28H38N4O3.ClH/c1-28(2)26(33)31(22-23-12-6-4-7-13-23)27(34)32(28)17-11-5-10-16-29-18-20-30(21-19-29)24-14-8-9-15-25(24)35-3;/h4,6-9,12-15H,5,10-11,16-22H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004647 (CHEMBL3233671) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccccc2F)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-11-5-3-6-12-22)26(34)32(27)16-10-4-9-15-29-17-19-30(20-18-29)24-14-8-7-13-23(24)28;/h3,5-8,11-14H,4,9-10,15-21H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004521 (CHEMBL3233402) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2)C(C1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N4O2.ClH/c1-32-29(36)31(26-14-6-2-7-15-26,27-16-8-3-9-17-27)35(30(32)37)21-13-5-12-20-33-22-24-34(25-23-33)28-18-10-4-11-19-28;/h2-4,6-11,14-19H,5,12-13,20-25H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004685 (CHEMBL3233677) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-6-7-20(28)16-23(19)30)26(37)35(27)11-5-3-4-10-32-12-14-33(15-13-32)21-8-9-22(29)24(31)17-21;/h6-9,16-17H,3-5,10-15,18H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004525 (CHEMBL3233668) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccccc2)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H36N4O2.ClH/c1-27(2)25(32)30(22-23-12-6-3-7-13-23)26(33)31(27)17-11-5-10-16-28-18-20-29(21-19-28)24-14-8-4-9-15-24;/h3-4,6-9,12-15H,5,10-11,16-22H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004684 (CHEMBL3233676) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-9-10-20(28)17-22(19)30)26(37)35(27)12-5-3-4-11-32-13-15-33(16-14-32)23-8-6-7-21(29)24(23)31;/h6-10,17H,3-5,11-16,18H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004520 (CHEMBL3233401) Show SMILES CCOc1ccccc1N1CCN(CCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H36N4O3/c1-3-38-28-18-11-10-17-27(28)34-23-21-33(22-24-34)19-12-20-35-30(37)32(2)29(36)31(35,25-13-6-4-7-14-25)26-15-8-5-9-16-26/h4-11,13-18H,3,12,19-24H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004756 (CHEMBL3233679) Show SMILES Cl.COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(C2=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C24H29FN4O4.ClH/c1-24(17-7-9-18(25)10-8-17)22(31)29(23(32)26-24)16-19(30)15-27-11-13-28(14-12-27)20-5-3-4-6-21(20)33-2;/h3-10,19,30H,11-16H2,1-2H3,(H,26,32);1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004591 (CHEMBL3233670) Show SMILES Cl.COc1cccc(c1)N1CCN(CCCCCN2C(=O)N(Cc3ccccc3)C(=O)C2(C)C)CC1 Show InChI InChI=1S/C28H38N4O3.ClH/c1-28(2)26(33)31(22-23-11-6-4-7-12-23)27(34)32(28)16-9-5-8-15-29-17-19-30(20-18-29)24-13-10-14-25(21-24)35-3;/h4,6-7,10-14,21H,5,8-9,15-20,22H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004682 (CHEMBL3233674) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2F)C(=O)N(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H33F3N4O2.ClH/c1-27(2)25(35)33(19-20-6-8-21(28)9-7-20)26(36)34(27)13-5-3-4-12-31-14-16-32(17-15-31)24-11-10-22(29)18-23(24)30;/h6-11,18H,3-5,12-17,19H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004523 (CHEMBL3233666) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2F)C(C)(C1=O)c1ccccc1 Show InChI InChI=1S/C26H33FN4O2.ClH/c1-26(21-11-5-3-6-12-21)24(32)28(2)25(33)31(26)16-10-4-9-15-29-17-19-30(20-18-29)23-14-8-7-13-22(23)27;/h3,5-8,11-14H,4,9-10,15-20H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004522 (CHEMBL3233665) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2)C(C)(C1=O)c1ccccc1 Show InChI InChI=1S/C26H34N4O2.ClH/c1-26(22-12-6-3-7-13-22)24(31)27(2)25(32)30(26)17-11-5-10-16-28-18-20-29(21-19-28)23-14-8-4-9-15-23;/h3-4,6-9,12-15H,5,10-11,16-21H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004647 (CHEMBL3233671) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccccc2F)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-11-5-3-6-12-22)26(34)32(27)16-10-4-9-15-29-17-19-30(20-18-29)24-14-8-7-13-23(24)28;/h3,5-8,11-14H,4,9-10,15-21H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004523 (CHEMBL3233666) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2F)C(C)(C1=O)c1ccccc1 Show InChI InChI=1S/C26H33FN4O2.ClH/c1-26(21-11-5-3-6-12-21)24(32)28(2)25(33)31(26)16-10-4-9-15-29-17-19-30(20-18-29)23-14-8-7-13-22(23)27;/h3,5-8,11-14H,4,9-10,15-20H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004680 (CHEMBL3233673) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2F)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H34F2N4O2.ClH/c1-27(2)25(34)32(20-21-9-5-3-6-10-21)26(35)33(27)14-8-4-7-13-30-15-17-31(18-16-30)24-12-11-22(28)19-23(24)29;/h3,5-6,9-12,19H,4,7-8,13-18,20H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004655 (CHEMBL3233672) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-9-5-3-6-10-22)26(34)32(27)16-8-4-7-15-29-17-19-30(20-18-29)24-13-11-23(28)12-14-24;/h3,5-6,9-14H,4,7-8,15-21H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004517 (CHEMBL1916745) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)N(C)C(=O)C2(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C30H34N4O3/c1-31-28(35)30(24-12-5-3-6-13-24,25-14-7-4-8-15-25)34(29(31)36)19-11-18-32-20-22-33(23-21-32)26-16-9-10-17-27(26)37-2/h3-10,12-17H,11,18-23H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004680 (CHEMBL3233673) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2F)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H34F2N4O2.ClH/c1-27(2)25(34)32(20-21-9-5-3-6-10-21)26(35)33(27)14-8-4-7-13-30-15-17-31(18-16-30)24-12-11-22(28)19-23(24)29;/h3,5-6,9-12,19H,4,7-8,13-18,20H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004682 (CHEMBL3233674) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2F)C(=O)N(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H33F3N4O2.ClH/c1-27(2)25(35)33(19-20-6-8-21(28)9-7-20)26(36)34(27)13-5-3-4-12-31-14-16-32(17-15-31)24-11-10-22(29)18-23(24)30;/h6-11,18H,3-5,12-17,19H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004685 (CHEMBL3233677) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-6-7-20(28)16-23(19)30)26(37)35(27)11-5-3-4-10-32-12-14-33(15-13-32)21-8-9-22(29)24(31)17-21;/h6-9,16-17H,3-5,10-15,18H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	301	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004683 (CHEMBL3233675) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H34F2N4O2.ClH/c1-27(2)25(34)32(20-21-6-8-22(28)9-7-21)26(35)33(27)15-5-3-4-14-30-16-18-31(19-17-30)24-12-10-23(29)11-13-24;/h6-13H,3-5,14-20H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004685 (CHEMBL3233677) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-6-7-20(28)16-23(19)30)26(37)35(27)11-5-3-4-10-32-12-14-33(15-13-32)21-8-9-22(29)24(31)17-21;/h6-9,16-17H,3-5,10-15,18H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	314	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004516 (CHEMBL1916746) Show SMILES CN1C(=O)N(CC(O)CN2CCN(CC2)c2ccccc2)C(C1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-30-27(35)29(23-11-5-2-6-12-23,24-13-7-3-8-14-24)33(28(30)36)22-26(34)21-31-17-19-32(20-18-31)25-15-9-4-10-16-25/h2-16,26,34H,17-22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004516 (CHEMBL1916746) Show SMILES CN1C(=O)N(CC(O)CN2CCN(CC2)c2ccccc2)C(C1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-30-27(35)29(23-11-5-2-6-12-23,24-13-7-3-8-14-24)33(28(30)36)22-26(34)21-31-17-19-32(20-18-31)25-15-9-4-10-16-25/h2-16,26,34H,17-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	353	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004684 (CHEMBL3233676) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H32Cl4N4O2.ClH/c1-27(2)25(36)34(18-19-9-10-20(28)17-22(19)30)26(37)35(27)12-5-3-4-11-32-13-15-33(16-14-32)23-8-6-7-21(29)24(23)31;/h6-10,17H,3-5,11-16,18H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	395	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004686 (CHEMBL3233678) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H33Cl3N4O2.ClH/c1-27(2)25(35)33(19-20-6-7-22(29)18-24(20)30)26(36)34(27)13-5-3-4-12-31-14-16-32(17-15-31)23-10-8-21(28)9-11-23;/h6-11,18H,3-5,12-17,19H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	456	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004683 (CHEMBL3233675) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H34F2N4O2.ClH/c1-27(2)25(34)32(20-21-6-8-22(28)9-7-21)26(35)33(27)15-5-3-4-14-30-16-18-31(19-17-30)24-12-10-23(29)11-13-24;/h6-13H,3-5,14-20H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004655 (CHEMBL3233672) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-9-5-3-6-10-22)26(34)32(27)16-8-4-7-15-29-17-19-30(20-18-29)24-13-11-23(28)12-14-24;/h3,5-6,9-14H,4,7-8,15-21H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004686 (CHEMBL3233678) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H33Cl3N4O2.ClH/c1-27(2)25(35)33(19-20-6-7-22(29)18-24(20)30)26(36)34(27)13-5-3-4-12-31-14-16-32(17-15-31)23-10-8-21(28)9-11-23;/h6-11,18H,3-5,12-17,19H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004647 (CHEMBL3233671) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccccc2F)C(=O)N(Cc2ccccc2)C1=O Show InChI InChI=1S/C27H35FN4O2.ClH/c1-27(2)25(33)31(21-22-11-5-3-6-12-22)26(34)32(27)16-10-4-9-15-29-17-19-30(20-18-29)24-14-8-7-13-23(24)28;/h3,5-8,11-14H,4,9-10,15-21H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004686 (CHEMBL3233678) Show SMILES Cl.CC1(C)N(CCCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)N(Cc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C27H33Cl3N4O2.ClH/c1-27(2)25(35)33(19-20-6-7-22(29)18-24(20)30)26(36)34(27)13-5-3-4-12-31-14-16-32(17-15-31)23-10-8-21(28)9-11-23;/h6-11,18H,3-5,12-17,19H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004591 (CHEMBL3233670) Show SMILES Cl.COc1cccc(c1)N1CCN(CCCCCN2C(=O)N(Cc3ccccc3)C(=O)C2(C)C)CC1 Show InChI InChI=1S/C28H38N4O3.ClH/c1-28(2)26(33)31(22-23-11-6-4-7-12-23)27(34)32(28)16-9-5-8-15-29-17-19-30(20-18-29)24-13-10-14-25(21-24)35-3;/h4,6-7,10-14,21H,5,8-9,15-20,22H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004521 (CHEMBL3233402) Show SMILES Cl.CN1C(=O)N(CCCCCN2CCN(CC2)c2ccccc2)C(C1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N4O2.ClH/c1-32-29(36)31(26-14-6-2-7-15-26,27-16-8-3-9-17-27)35(30(32)37)21-13-5-12-20-33-22-24-34(25-23-33)28-18-10-4-11-19-28;/h2-4,6-11,14-19H,5,12-13,20-25H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair

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