| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50004524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1337826 (CHEMBL3240654) |
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| Ki | 34±n/a nM |
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| Citation |  Handzlik, J; Bojarski, AJ; Satala, G; Kubacka, M; Sadek, B; Ashoor, A; Siwek, A; Wiecek, M; Kucwaj, K; Filipek, B; Kiec-Kononowicz, K SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT(7) receptor ligands among phenylpiperazine hydantoin derivatives. Eur J Med Chem78:324-39 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50004524 |
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| n/a |
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| Name | BDBM50004524 |
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| Synonyms: | CHEMBL3233667 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37ClN4O3 |
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| Mol. Mass. | 501.061 |
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| SMILES | Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 |
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| Structure | 
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