BindingDB PrimarySearch

Found 26 hits with Last Name = 'assis' and Initial = 'dm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM241952 (Fukugetin) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of S�o Paulo					Assay Description To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...				J Enzyme Inhib Med Chem 28: 661-70 (2013) Article DOI: 10.3109/14756366.2012.668539 BindingDB Entry DOI: 10.7270/Q2T43S03
Federal University of S�o Paulo					More data for this Ligand-Target Pair
Kallikrein-2 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated fo...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Mixed-type inhibition of human tissue kallikrein-1 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated fo...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM241952 (Fukugetin) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of S�o Paulo					Assay Description To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...				J Enzyme Inhib Med Chem 28: 661-70 (2013) Article DOI: 10.3109/14756366.2012.668539 BindingDB Entry DOI: 10.7270/Q2T43S03
Federal University of S�o Paulo					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50157741 (CHEMBL374508 \| E-64 \| E64) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50286441 ((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50378032 (CHEMBL452483 \| Guttiferone A) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50378032 (CHEMBL452483 \| Guttiferone A) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50378032 (CHEMBL452483 \| Guttiferone A) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin G by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-2 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-1 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-5 [D153N] (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-5 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Prostate-specific antigen (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-3 expressed in baculovirus infected insect cells using Abz-KLYSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-6 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-6 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-7 (Homo sapiens (Human))	BDBM50292533 (CHEMBL446790 \| Fukugetin) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Campus Inc Curated by ChEMBL					Assay Description Inhibition of human tissue kallikrein-7 expressed in baculovirus infected insect cells using Abz-KLYSSQ-EDDnp as substrate preincubated for 10 mins f...				Bioorg Med Chem Lett 26: 1485-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.039 BindingDB Entry DOI: 10.7270/Q2862J9K
Campus Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50249351 (CHEMBL470519 \| epiclusianone) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50249351 (CHEMBL470519 \| epiclusianone) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin G by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50249351 (CHEMBL470519 \| epiclusianone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50249352 (CHEMBL470520 \| garciniaphenone) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin G by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50249352 (CHEMBL470520 \| garciniaphenone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50249352 (CHEMBL470520 \| garciniaphenone) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50249353 (1,1,3-trihydroxybenzophenone \| 2,2',4-trihydroxybe...) Show SMILES Oc1ccc(C(=O)c2ccccc2O)c(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM22726 (Benzophenone \| CHEMBL90039 \| diphenylmethanone) Show SMILES O=C(c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin B by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50249353 (1,1,3-trihydroxybenzophenone \| 2,2',4-trihydroxybe...) Show SMILES Oc1ccc(C(=O)c2ccccc2O)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of cathepsin G by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50249353 (1,1,3-trihydroxybenzophenone \| 2,2',4-trihydroxybe...) Show SMILES Oc1ccc(C(=O)c2ccccc2O)c(O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM22726 (Benzophenone \| CHEMBL90039 \| diphenylmethanone) Show SMILES O=C(c1ccccc1)c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	3.47E+6	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Alfenas Curated by ChEMBL					Assay Description Inhibition of Carica papaya papain by spectrofluorimetry				Eur J Med Chem 44: 1230-9 (2009) Article DOI: 10.1016/j.ejmech.2008.09.018 BindingDB Entry DOI: 10.7270/Q26974HM
Federal University of Alfenas Curated by ChEMBL					More data for this Ligand-Target Pair