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TargetKallikrein 2
LigandBDBM50292533
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1558619
IC50 3200±n/a nM
Citation Santos JAKondo MYFreitas RFdos Santos MHRamalho TCAssis DMJuliano LJuliano MAPuzer L The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins. Bioorg Med Chem Lett 26:1485-9 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Kallikrein 2
Name:Kallikrein 2
Synonyms:Glandular kallikrein-1 | Kallikrein-2 | Tissue kallikrein-2 | hGK-1
Type:PROTEIN
Mol. Mass.:28673.68
Organism:Homo sapiens (Human)
Description:ChEMBL_862797
Residue:261
Sequence:
MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP
AVYTKVVHYRKWIKDTIAANP
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  Blast E-value cutoff:
BDBM50292533
n/a
NameBDBM50292533
Synonyms:CHEMBL446790 | Fukugetin
TypeSmall organic molecule
Emp. Form.C30H22O11
Mol. Mass.558.4891
SMILESOc1ccc(cc1)[C@@H]1Oc2cc(O)cc(O)c2C(=O)[C@H]1c1c(O)cc(O)c2C(=O)CC(Oc12)c1ccc(O)c(O)c1 |r|
Structure
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