BindingDB PrimarySearch

Found 12 hits with Last Name = 'baker' and Initial = 'at'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066275 (CHEMBL3401548) Show SMILES OC(\C=C\c1ccccn1)c1ccccc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066274 (CHEMBL3401549) Show SMILES OC(\C=C\c1ccncc1)c1ccccc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	8.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066275 (CHEMBL3401548) Show SMILES OC(\C=C\c1ccccn1)c1ccccc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066274 (CHEMBL3401549) Show SMILES OC(\C=C\c1ccncc1)c1ccccc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM50271369 (CHEMBL4127400) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM50271365 (CHEMBL4127261) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM50236893 (CHEBI:15664 \| CHEMBL145233) Show SMILES C\C(CO)=C/COP(O)(=O)OP(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM12578 (2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...) Show SMILES OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	487	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM50271366 (CHEMBL4126163) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair
Butyrophilin subfamily 3 member A1 (Homo sapiens (Human))	BDBM50271368 (CHEMBL4126016) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and C...				J Med Chem 61: 2111-2117 (2018) Article DOI: 10.1021/acs.jmedchem.7b01824 BindingDB Entry DOI: 10.7270/Q2JD509N
Cardiff University Curated by ChEMBL					More data for this Ligand-Target Pair