Compile Data Set for Download or QSAR

Found 80 hits with Last Name = 'barsotti' and Initial = 'am'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453246 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-4-28(2,3)34-25(35)17-37-22-7-5-6-19(12-22)26-32-24-16-36-15-23(24)27(33-26)31-21-10-8-18(9-11-21)20-13-29-30-14-20/h5-14H,4,15-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453265 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)34-25(35)17-37-22-6-4-5-19(13-22)26-32-24-11-12-36-16-23(24)27(33-26)31-21-9-7-18(8-10-21)20-14-29-30-15-20/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453264 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-3-22(4-2)32-27(36)18-38-24-7-5-6-20(14-24)28-34-26-12-13-37-17-25(26)29(35-28)33-23-10-8-19(9-11-23)21-15-30-31-16-21/h5-11,14-16,22H,3-4,12-13,17-18H2,1-2H3,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453265 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)34-25(35)17-37-22-6-4-5-19(13-22)26-32-24-11-12-36-16-23(24)27(33-26)31-21-9-7-18(8-10-21)20-14-29-30-15-20/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453246 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-4-28(2,3)34-25(35)17-37-22-7-5-6-19(12-22)26-32-24-16-36-15-23(24)27(33-26)31-21-10-8-18(9-11-21)20-13-29-30-14-20/h5-14H,4,15-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453228 (US10729691, Example 13) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C28H28N6O3/c35-26(31-21-5-1-2-6-21)17-37-23-7-3-4-19(12-23)27-33-25-16-36-15-24(25)28(34-27)32-22-10-8-18(9-11-22)20-13-29-30-14-20/h3-4,7-14,21H,1-2,5-6,15-17H2,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453264 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-3-22(4-2)32-27(36)18-38-24-7-5-6-20(14-24)28-34-26-12-13-37-17-25(26)29(35-28)33-23-10-8-19(9-11-23)21-15-30-31-16-21/h5-11,14-16,22H,3-4,12-13,17-18H2,1-2H3,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50514308 (CHEMBL4448899) Show SMILES Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F Show InChI InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538375 (CHEMBL4633651) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H31N7O2/c1-28(2,3)35-25(36)17-37-22-6-4-5-19(13-22)26-33-24-11-12-29-16-23(24)27(34-26)32-21-9-7-18(8-10-21)20-14-30-31-15-20/h4-10,13-15,29H,11-12,16-17H2,1-3H3,(H,30,31)(H,35,36)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453227 (US10729691, Example 12) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCC1 Show InChI InChI=1S/C27H26N6O3/c34-25(30-20-4-2-5-20)16-36-22-6-1-3-18(11-22)26-32-24-15-35-14-23(24)27(33-26)31-21-9-7-17(8-10-21)19-12-28-29-13-19/h1,3,6-13,20H,2,4-5,14-16H2,(H,28,29)(H,30,34)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538383 (CHEMBL4645036) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CC1 Show InChI InChI=1S/C31H33N7O2/c1-31(12-13-31)37-28(39)19-40-25-4-2-3-21(15-25)29-35-27-11-14-38(24-9-10-24)18-26(27)30(36-29)34-23-7-5-20(6-8-23)22-16-32-33-17-22/h2-8,15-17,24H,9-14,18-19H2,1H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453217 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-16(2)29-24(33)15-35-21-5-3-4-18(10-21)25-31-23-14-34-13-22(23)26(32-25)30-20-8-6-17(7-9-20)19-11-27-28-12-19/h3-12,16H,13-15H2,1-2H3,(H,27,28)(H,29,33)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453228 (US10729691, Example 13) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C28H28N6O3/c35-26(31-21-5-1-2-6-21)17-37-23-7-3-4-19(12-23)27-33-25-16-36-15-24(25)28(34-27)32-22-10-8-18(9-11-22)20-13-29-30-14-20/h3-4,7-14,21H,1-2,5-6,15-17H2,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538382 (CHEMBL4649311) Show SMILES CC(CF)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H36FN7O2/c1-20(15-32)39-13-12-27-26(18-39)30(35-24-10-8-21(9-11-24)23-16-33-34-17-23)37-29(36-27)22-6-5-7-25(14-22)41-19-28(40)38-31(2,3)4/h5-11,14,16-17,20H,12-13,15,18-19H2,1-4H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538374 (CHEMBL4637134) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H33N7O2/c1-3-22(4-2)33-27(37)18-38-24-7-5-6-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h5-11,14-16,22,30H,3-4,12-13,17-18H2,1-2H3,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538391 (CHEMBL4642046) Show SMILES COCC(C)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C32H39N7O3/c1-21(19-41-5)39-14-13-28-27(18-39)31(35-25-11-9-22(10-12-25)24-16-33-34-17-24)37-30(36-28)23-7-6-8-26(15-23)42-20-29(40)38-32(2,3)4/h6-12,15-17,21H,13-14,18-20H2,1-5H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538373 (CHEMBL4635564) Show SMILES O=C(COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C29H31N7O2/c37-27(33-22-5-1-2-6-22)18-38-24-7-3-4-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h3-4,7-11,14-16,22,30H,1-2,5-6,12-13,17-18H2,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538384 (CHEMBL4645662) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CC1 Show InChI InChI=1S/C30H33N7O2/c1-19(2)33-28(38)18-39-25-5-3-4-21(14-25)29-35-27-12-13-37(24-10-11-24)17-26(27)30(36-29)34-23-8-6-20(7-9-23)22-15-31-32-16-22/h3-9,14-16,19,24H,10-13,17-18H2,1-2H3,(H,31,32)(H,33,38)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538390 (CHEMBL4638542) Show SMILES COCCN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H37N7O3/c1-31(2,3)37-28(39)20-41-25-7-5-6-22(16-25)29-35-27-12-13-38(14-15-40-4)19-26(27)30(36-29)34-24-10-8-21(9-11-24)23-17-32-33-18-23/h5-11,16-18H,12-15,19-20H2,1-4H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538389 (CHEMBL4634012) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCOC1 Show InChI InChI=1S/C32H37N7O3/c1-32(2,3)38-29(40)20-42-26-6-4-5-22(15-26)30-36-28-11-13-39(25-12-14-41-19-25)18-27(28)31(37-30)35-24-9-7-21(8-10-24)23-16-33-34-17-23/h4-10,15-17,25H,11-14,18-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453248 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES FC(F)(F)CNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C25H21F3N6O3/c26-25(27,28)14-29-22(35)13-37-19-3-1-2-16(8-19)23-33-21-12-36-11-20(21)24(34-23)32-18-6-4-15(5-7-18)17-9-30-31-10-17/h1-10H,11-14H2,(H,29,35)(H,30,31)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538389 (CHEMBL4634012) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCOC1 Show InChI InChI=1S/C32H37N7O3/c1-32(2,3)38-29(40)20-42-26-6-4-5-22(15-26)30-36-28-11-13-39(25-12-14-41-19-25)18-27(28)31(37-30)35-24-9-7-21(8-10-24)23-16-33-34-17-23/h4-10,15-17,25H,11-14,18-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538390 (CHEMBL4638542) Show SMILES COCCN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H37N7O3/c1-31(2,3)37-28(39)20-41-25-7-5-6-22(16-25)29-35-27-12-13-38(14-15-40-4)19-26(27)30(36-29)34-24-10-8-21(9-11-24)23-17-32-33-18-23/h5-11,16-18H,12-15,19-20H2,1-4H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538386 (CHEMBL4647401) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H35N7O2/c1-32(13-14-32)38-29(40)20-41-26-7-2-4-22(16-26)30-36-28-12-15-39(25-5-3-6-25)19-27(28)31(37-30)35-24-10-8-21(9-11-24)23-17-33-34-18-23/h2,4,7-11,16-18,25H,3,5-6,12-15,19-20H2,1H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453227 (US10729691, Example 12) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCC1 Show InChI InChI=1S/C27H26N6O3/c34-25(30-20-4-2-5-20)16-36-22-6-1-3-18(11-22)26-32-24-15-35-14-23(24)27(33-26)31-21-9-7-17(8-10-21)19-12-28-29-13-19/h1,3,6-13,20H,2,4-5,14-16H2,(H,28,29)(H,30,34)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538383 (CHEMBL4645036) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CC1 Show InChI InChI=1S/C31H33N7O2/c1-31(12-13-31)37-28(39)19-40-25-4-2-3-21(15-25)29-35-27-11-14-38(24-9-10-24)18-26(27)30(36-29)34-23-7-5-20(6-8-23)22-16-32-33-17-22/h2-8,15-17,24H,9-14,18-19H2,1H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538375 (CHEMBL4633651) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H31N7O2/c1-28(2,3)35-25(36)17-37-22-6-4-5-19(13-22)26-33-24-11-12-29-16-23(24)27(34-26)32-21-9-7-18(8-10-21)20-14-30-31-15-20/h4-10,13-15,29H,11-12,16-17H2,1-3H3,(H,30,31)(H,35,36)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538382 (CHEMBL4649311) Show SMILES CC(CF)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H36FN7O2/c1-20(15-32)39-13-12-27-26(18-39)30(35-24-10-8-21(9-11-24)23-16-33-34-17-23)37-29(36-27)22-6-5-7-25(14-22)41-19-28(40)38-31(2,3)4/h5-11,14,16-17,20H,12-13,15,18-19H2,1-4H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538387 (CHEMBL4642809) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C31H35N7O2/c1-20(2)34-29(39)19-40-26-8-3-5-22(15-26)30-36-28-13-14-38(25-6-4-7-25)18-27(28)31(37-30)35-24-11-9-21(10-12-24)23-16-32-33-17-23/h3,5,8-12,15-17,20,25H,4,6-7,13-14,18-19H2,1-2H3,(H,32,33)(H,34,39)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453219 (US10729691, Example 4) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CC1 Show InChI InChI=1S/C26H24N6O3/c33-24(29-19-8-9-19)15-35-21-3-1-2-17(10-21)25-31-23-14-34-13-22(23)26(32-25)30-20-6-4-16(5-7-20)18-11-27-28-12-18/h1-7,10-12,19H,8-9,13-15H2,(H,27,28)(H,29,33)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538386 (CHEMBL4647401) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H35N7O2/c1-32(13-14-32)38-29(40)20-41-26-7-2-4-22(16-26)30-36-28-12-15-39(25-5-3-6-25)19-27(28)31(37-30)35-24-10-8-21(9-11-24)23-17-33-34-18-23/h2,4,7-11,16-18,25H,3,5-6,12-15,19-20H2,1H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538385 (CHEMBL4632395) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H37N7O2/c1-32(2,3)38-29(40)20-41-26-9-4-6-22(16-26)30-36-28-14-15-39(25-7-5-8-25)19-27(28)31(37-30)35-24-12-10-21(11-13-24)23-17-33-34-18-23/h4,6,9-13,16-18,25H,5,7-8,14-15,19-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538391 (CHEMBL4642046) Show SMILES COCC(C)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C32H39N7O3/c1-21(19-41-5)39-14-13-28-27(18-39)31(35-25-11-9-22(10-12-25)24-16-33-34-17-24)37-30(36-28)23-7-6-8-26(15-23)42-20-29(40)38-32(2,3)4/h6-12,15-17,21H,13-14,18-20H2,1-5H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538385 (CHEMBL4632395) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H37N7O2/c1-32(2,3)38-29(40)20-41-26-9-4-6-22(16-26)30-36-28-14-15-39(25-7-5-8-25)19-27(28)31(37-30)35-24-12-10-21(11-13-24)23-17-33-34-18-23/h4,6,9-13,16-18,25H,5,7-8,14-15,19-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	287	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453217 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-16(2)29-24(33)15-35-21-5-3-4-18(10-21)25-31-23-14-34-13-22(23)26(32-25)30-20-8-6-17(7-9-20)19-11-27-28-12-19/h3-12,16H,13-15H2,1-2H3,(H,27,28)(H,29,33)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	289	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538365 (CHEMBL4632920) Show SMILES CCCNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-2-10-27-24(33)16-35-21-5-3-4-18(11-21)25-31-23-15-34-14-22(23)26(32-25)30-20-8-6-17(7-9-20)19-12-28-29-13-19/h3-9,11-13H,2,10,14-16H2,1H3,(H,27,33)(H,28,29)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538368 (CHEMBL4649877) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)Nc1ccccc1 Show InChI InChI=1S/C29H24N6O3/c36-27(32-22-6-2-1-3-7-22)18-38-24-8-4-5-20(13-24)28-34-26-17-37-16-25(26)29(35-28)33-23-11-9-19(10-12-23)21-14-30-31-15-21/h1-15H,16-18H2,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538381 (CHEMBL4648473) Show SMILES CC(C)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H37N7O2/c1-20(2)38-14-13-27-26(18-38)30(34-24-11-9-21(10-12-24)23-16-32-33-17-23)36-29(35-27)22-7-6-8-25(15-22)40-19-28(39)37-31(3,4)5/h6-12,15-17,20H,13-14,18-19H2,1-5H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	326	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538371 (CHEMBL4635864) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(C)Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C30H35N7O2/c1-5-30(2,3)36-27(38)19-39-24-8-6-7-21(15-24)28-34-26-13-14-37(4)18-25(26)29(35-28)33-23-11-9-20(10-12-23)22-16-31-32-17-22/h6-12,15-17H,5,13-14,18-19H2,1-4H3,(H,31,32)(H,36,38)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453252 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-methy...) Show SMILES CN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C29H33N7O2/c1-29(2,3)35-26(37)18-38-23-7-5-6-20(14-23)27-33-25-12-13-36(4)17-24(25)28(34-27)32-22-10-8-19(9-11-22)21-15-30-31-16-21/h5-11,14-16H,12-13,17-18H2,1-4H3,(H,30,31)(H,35,37)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538372 (CHEMBL4637262) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H29N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-10-11-28-15-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-9,12-14,17,28H,10-11,15-16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453252 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-methy...) Show SMILES CN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C29H33N7O2/c1-29(2,3)35-26(37)18-38-23-7-5-6-20(14-23)27-33-25-12-13-36(4)17-24(25)28(34-27)32-22-10-8-19(9-11-22)21-15-30-31-16-21/h5-11,14-16H,12-13,17-18H2,1-4H3,(H,30,31)(H,35,37)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538370 (CHEMBL4633530) Show SMILES CN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC2CCCC2)c1 Show InChI InChI=1S/C30H33N7O2/c1-37-14-13-27-26(18-37)30(34-24-11-9-20(10-12-24)22-16-31-32-17-22)36-29(35-27)21-5-4-8-25(15-21)39-19-28(38)33-23-6-2-3-7-23/h4-5,8-12,15-17,23H,2-3,6-7,13-14,18-19H2,1H3,(H,31,32)(H,33,38)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	391	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538371 (CHEMBL4635864) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(C)Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C30H35N7O2/c1-5-30(2,3)36-27(38)19-39-24-8-6-7-21(15-24)28-34-26-13-14-37(4)18-25(26)29(35-28)33-23-11-9-20(10-12-23)22-16-31-32-17-22/h6-12,15-17H,5,13-14,18-19H2,1-4H3,(H,31,32)(H,36,38)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	391	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538388 (CHEMBL4648189) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1(C)CC1 Show InChI InChI=1S/C31H35N7O2/c1-20(2)34-28(39)19-40-25-6-4-5-22(15-25)29-36-27-11-14-38(31(3)12-13-31)18-26(27)30(37-29)35-24-9-7-21(8-10-24)23-16-32-33-17-23/h4-10,15-17,20H,11-14,18-19H2,1-3H3,(H,32,33)(H,34,39)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538381 (CHEMBL4648473) Show SMILES CC(C)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H37N7O2/c1-20(2)38-14-13-27-26(18-38)30(34-24-11-9-21(10-12-24)23-16-32-33-17-23)36-29(35-27)22-7-6-8-25(15-22)40-19-28(39)37-31(3,4)5/h6-12,15-17,20H,13-14,18-19H2,1-5H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538374 (CHEMBL4637134) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H33N7O2/c1-3-22(4-2)33-27(37)18-38-24-7-5-6-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h5-11,14-16,22,30H,3-4,12-13,17-18H2,1-2H3,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	441	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538365 (CHEMBL4632920) Show SMILES CCCNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-2-10-27-24(33)16-35-21-5-3-4-18(11-21)25-31-23-15-34-14-22(23)26(32-25)30-20-8-6-17(7-9-20)19-12-28-29-13-19/h3-9,11-13H,2,10,14-16H2,1H3,(H,27,33)(H,28,29)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50538373 (CHEMBL4635564) Show SMILES O=C(COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C29H31N7O2/c37-27(33-22-5-1-2-6-22)18-38-24-7-3-4-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h3-4,7-11,14-16,22,30H,1-2,5-6,12-13,17-18H2,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	459	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538377 (CHEMBL4641999) Show SMILES CCN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C30H35N7O2/c1-5-37-14-13-26-25(18-37)29(33-23-11-9-20(10-12-23)22-16-31-32-17-22)35-28(34-26)21-7-6-8-24(15-21)39-19-27(38)36-30(2,3)4/h6-12,15-17H,5,13-14,18-19H2,1-4H3,(H,31,32)(H,36,38)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	482	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair

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