Compile Data Set for Download or QSAR

Found 128 hits with Last Name = 'bence' and Initial = 'nf'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575632 (US11464802, Compound 1) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575633 (US11464802, Compound 2) Show SMILES C[C@H]1C[C@@H](C)CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575641 (US11464802, Compound 10) Show SMILES Cn1cnnc1CC1(COC1)c1cccc(c1)N1Cc2c(cc(CN3CCC(F)(F)[C@H](C3)C#N)cc2C(F)(F)F)C1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575659 (US11464802, Compound 22) Show SMILES C[C@H]1C[C@H](CO)CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575660 (US11464802, Compound 23) Show SMILES C[C@H]1C[C@@H](CO)CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575661 (US11464802, Compound 24) Show SMILES CC1CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)CC2)CCC1(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575669 (US11464802, Compound 32) Show SMILES C[C@@H]1CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)C2(Cc3nncn3C)COC2)C2CC2)CCC1(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575673 (US11464802, Compound 36) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C(F)F)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575676 (US11464802, Compound 39) Show SMILES CCOc1cc(cc(n1)N1Cc2c(cc(CN3CCC[C@H](C)C3)cc2C(F)(F)F)C1=O)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575677 (US11464802, Compound 40) Show SMILES CCOc1cc(cc(n1)N1Cc2c(cc(CN3CCC[C@H](C)C3)nc2C2CC2)C1=O)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575681 (US11464802, Compound 44) Show SMILES CCNc1cc(cc(n1)N1Cc2c(cc(CN3CCC[C@H](C)C3)cc2C(F)(F)F)C1=O)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575685 (US11464802, Compound 49) Show SMILES C[C@H](N1CCC(F)(F)[C@H](C)C1)c1cc2C(=O)N(Cc2c(n1)C1CC1)c1cccc(c1)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575686 (US11464802, Compound 50) Show SMILES C[C@@H](N1CCC(F)(F)[C@H](C)C1)c1cc2C(=O)N(Cc2c(n1)C1CC1)c1cccc(c1)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575687 (US11464802, Compound 51) Show SMILES C[C@H](N1CCC[C@H](C)C1)c1cc2C(=O)N(Cc2c(n1)C1CC1)c1cccc(c1)C1(Cc2nncn2C)COC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585797 (US11530229, Compound 12) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CNC3CC4C(C3)C4(F)F)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(8.23,-1.35,;6.77,-1.83,;6.29,-3.29,;4.75,-3.29,;4.28,-1.83,;5.52,-.92,;5.52,.62,;6.86,1.39,;7.94,.3,;9.03,1.39,;7.94,2.48,;10.57,1.39,;12.11,1.39,;5.52,2.16,;5.52,3.7,;4.19,4.47,;2.85,3.7,;2.85,2.16,;4.19,1.39,;1.52,1.39,;1.36,-.15,;-.15,-.47,;-.92,.87,;-2.46,.87,;-3.23,-.47,;-4.77,-.47,;-5.54,-1.8,;-7.08,-1.8,;-7.98,-.55,;-9.45,-1.03,;-9.45,-2.57,;-7.98,-3.04,;-10.78,-1.8,;-12.11,-1.03,;-12.11,-2.57,;-2.46,-1.8,;-.92,-1.8,;-.15,-3.13,;-.92,-4.47,;1.39,-3.13,;.62,-4.47,;.11,2.01,;-.21,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585803 (US11530229, Compound 18) Show SMILES C[C@H]1C[C@@H](C)CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:37.43,wD:28.30,1.0,3.3,(-10.75,-2.39,;-9.21,-2.39,;-8.44,-3.72,;-6.9,-3.72,;-6.5,-5.21,;-6.13,-2.39,;-6.9,-1.06,;-6.13,.28,;-4.59,.28,;-3.82,1.61,;-2.28,1.61,;-1.25,2.76,;-1.57,4.26,;.16,2.13,;-0,.6,;-1.51,.28,;-2.28,-1.06,;-3.82,-1.06,;-1.51,-2.39,;-2.28,-3.72,;.03,-2.39,;-.74,-3.72,;1.49,2.9,;1.49,4.44,;2.82,5.21,;4.16,4.44,;4.16,2.9,;2.82,2.13,;5.49,2.13,;4.16,1.36,;4.16,-.18,;2.91,-1.09,;3.39,-2.55,;4.93,-2.55,;5.4,-1.09,;6.87,-.61,;6.58,1.04,;7.67,2.13,;6.58,3.22,;9.21,2.13,;10.75,2.13,;-8.44,-1.06,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585804 (US11530229, Compound 19) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:36.42,wD:27.29,1.0,(-10.75,-3.13,;-9.21,-3.13,;-8.44,-4.47,;-6.9,-4.47,;-6.13,-3.13,;-6.9,-1.8,;-6.13,-.47,;-4.59,-.47,;-3.82,.87,;-2.28,.87,;-1.25,2.01,;-1.57,3.52,;.16,1.39,;-0,-.15,;-1.51,-.47,;-2.28,-1.8,;-3.82,-1.8,;-1.51,-3.13,;-2.28,-4.47,;.03,-3.13,;-.74,-4.47,;1.49,2.16,;1.49,3.7,;2.82,4.47,;4.16,3.7,;4.16,2.16,;2.82,1.39,;5.49,1.39,;4.16,.62,;4.16,-.92,;2.91,-1.83,;3.39,-3.29,;4.93,-3.29,;5.4,-1.83,;6.87,-1.35,;6.58,.3,;7.67,1.39,;6.58,2.48,;9.21,1.39,;10.75,1.39,;-8.44,-1.8,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585805 (US11530229, Compound 20) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,27.29,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585806 (US11530229, Compound 21) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,27.29,wD:7.14,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585810 (US11530229, Compound 25) Show SMILES CC1CCCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:37.43,wD:28.30,(-10.83,-2.31,;-9.32,-2.65,;-8.98,-4.15,;-7.59,-4.82,;-6.21,-4.15,;-5.86,-2.65,;-6.82,-1.45,;-6.05,-.11,;-4.51,-.11,;-3.74,1.22,;-2.2,1.22,;-1.17,2.37,;-1.49,3.87,;.23,1.74,;.07,.21,;-1.43,-.11,;-2.2,-1.45,;-3.74,-1.45,;-1.43,-2.78,;-2.2,-4.11,;.11,-2.78,;-.66,-4.11,;1.57,2.51,;1.57,4.05,;2.9,4.82,;4.23,4.05,;4.23,2.51,;2.9,1.74,;5.57,1.74,;4.23,.97,;4.23,-.57,;2.99,-1.48,;3.46,-2.94,;5,-2.94,;5.48,-1.48,;6.94,-1,;6.66,.65,;7.75,1.74,;6.66,2.83,;9.29,1.74,;10.83,1.74,;-8.36,-1.45,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585816 (US11530229, Compound 31) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CNC3CCC(C)(C)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585834 (US11530229, Compound 49) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCC[C@@H](C3)C(F)(F)F)nc2C2CC2)C1=O |r,wU:9.12,wD:7.14,30.35,(6.86,-1.25,;5.4,-1.73,;4.92,-3.19,;3.38,-3.19,;2.9,-1.73,;4.15,-.82,;4.15,.72,;5.48,1.49,;6.57,.4,;7.66,1.49,;6.57,2.58,;9.2,1.49,;10.74,1.49,;4.15,2.26,;4.15,3.8,;2.82,4.57,;1.48,3.8,;1.48,2.26,;2.82,1.49,;.15,1.49,;-.01,-.04,;-1.52,-.36,;-2.29,.97,;-3.83,.97,;-4.6,-.36,;-6.14,-.36,;-6.91,-1.7,;-6.12,-3.03,;-6.89,-4.36,;-8.43,-4.36,;-9.2,-3.03,;-8.43,-1.7,;-10.74,-3.03,;-11.51,-1.7,;-11.51,-4.36,;-12.28,-3.03,;-3.83,-1.7,;-2.29,-1.7,;-1.52,-3.03,;-1.52,-4.57,;-.18,-3.8,;-1.26,2.12,;-1.58,3.62,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585838 (US11530229, Compound 53) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(NC(=O)c2cc(CN3CCC4(CC4)C3)cc(n2)C2CC2)c1 |r,wU:9.12,wD:7.14,(8.11,-3.9,;8.58,-2.44,;10.05,-1.96,;10.05,-.42,;8.58,.05,;7.68,-1.19,;6.14,-1.19,;5.37,.14,;6.46,1.23,;5.37,2.32,;4.28,1.23,;5.37,3.86,;5.37,5.4,;4.6,-1.19,;5.37,-2.53,;4.6,-3.86,;3.06,-3.86,;2.29,-2.53,;.75,-2.53,;-.02,-1.19,;.75,.14,;-1.56,-1.19,;-2.33,.14,;-3.87,.14,;-4.61,1.47,;-6.15,1.47,;-7.05,.23,;-8.52,.7,;-8.52,2.24,;-9.14,3.65,;-10.05,2.4,;-7.05,2.72,;-4.64,-1.19,;-3.87,-2.53,;-2.33,-2.53,;-4.64,-3.86,;-5.98,-4.63,;-4.64,-5.4,;3.06,-1.19,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585839 (US11530229, Compound 54) Show SMILES C[C@H]1C[C@@H](C)CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C2CC2)C1 |r,wU:32.37,wD:23.24,1.0,3.3,(-9.64,4.14,;-8.87,2.81,;-9.64,1.47,;-8.87,.14,;-9.64,-1.2,;-7.33,.14,;-6.56,1.47,;-5.02,1.47,;-4.28,.14,;-5.05,-1.19,;-4.28,-2.53,;-2.74,-2.53,;-1.97,-1.19,;-2.74,.14,;-.43,-1.19,;.34,.14,;.34,-2.53,;1.88,-2.53,;2.65,-3.86,;4.19,-3.86,;4.96,-2.53,;4.19,-1.19,;2.65,-1.19,;4.96,.14,;5.73,-1.19,;7.27,-1.19,;8.17,.05,;9.64,-.42,;9.64,-1.96,;8.17,-2.44,;7.7,-3.9,;6.05,1.23,;4.96,2.32,;3.87,1.23,;4.96,3.86,;4.96,5.4,;-5.05,-3.86,;-6.39,-4.63,;-5.05,-5.4,;-7.33,2.81,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585840 (US11530229, Compound 55) Show SMILES C[C@H]1CCCN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C2CC2)C1 |r,wU:31.36,wD:22.23,1.0,(-9.64,4.14,;-8.87,2.81,;-9.64,1.47,;-8.87,.14,;-7.33,.14,;-6.56,1.47,;-5.02,1.47,;-4.28,.14,;-5.05,-1.19,;-4.28,-2.53,;-2.74,-2.53,;-1.97,-1.19,;-2.74,.14,;-.43,-1.19,;.34,.14,;.34,-2.53,;1.88,-2.53,;2.65,-3.86,;4.19,-3.86,;4.96,-2.53,;4.19,-1.19,;2.65,-1.19,;4.96,.14,;5.73,-1.19,;7.27,-1.19,;8.17,.05,;9.64,-.42,;9.64,-1.96,;8.17,-2.44,;7.7,-3.9,;6.05,1.23,;4.96,2.32,;3.87,1.23,;4.96,3.86,;4.96,5.4,;-5.05,-3.86,;-6.39,-4.63,;-5.05,-5.4,;-7.33,2.81,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585841 (US11530229, Compound 56) Show SMILES C[C@@H]1CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C2CC2)CCO1 |r,wU:29.34,wD:20.21,1.0,(-9.64,4.14,;-8.87,2.81,;-7.33,2.81,;-6.56,1.47,;-5.02,1.47,;-4.28,.14,;-5.05,-1.19,;-4.28,-2.53,;-2.74,-2.53,;-1.97,-1.19,;-2.74,.14,;-.43,-1.19,;.34,.14,;.34,-2.53,;1.88,-2.53,;2.65,-3.86,;4.19,-3.86,;4.96,-2.53,;4.19,-1.19,;2.65,-1.19,;4.96,.14,;5.73,-1.19,;7.27,-1.19,;8.17,.05,;9.64,-.42,;9.64,-1.96,;8.17,-2.44,;7.7,-3.9,;6.05,1.23,;4.96,2.32,;3.87,1.23,;4.96,3.86,;4.96,5.4,;-5.05,-3.86,;-6.39,-4.63,;-5.05,-5.4,;-7.33,.14,;-8.87,.14,;-9.64,1.47,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585842 (US11530229, Compound 57) Show SMILES C[C@@H]1CN(Cc2cc(nc(n2)C2CC2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)CCC1(F)F |r,wU:32.38,wD:23.25,1.0,(-8.97,4.14,;-8.2,2.81,;-6.66,2.81,;-5.89,1.47,;-4.35,1.47,;-3.62,.14,;-2.08,.14,;-1.31,-1.19,;-2.08,-2.53,;-3.62,-2.53,;-4.39,-1.19,;-4.39,-3.86,;-5.72,-4.63,;-4.39,-5.4,;.23,-1.19,;1,.14,;1,-2.53,;2.54,-2.53,;3.31,-3.86,;4.85,-3.86,;5.62,-2.53,;4.85,-1.19,;3.31,-1.19,;5.62,.14,;6.39,-1.19,;7.93,-1.19,;8.84,.05,;10.3,-.42,;10.3,-1.96,;8.84,-2.44,;8.36,-3.9,;6.71,1.23,;5.62,2.32,;4.53,1.23,;5.62,3.86,;5.62,5.4,;-6.66,.14,;-8.2,.14,;-8.97,1.47,;-10.06,.38,;-10.3,2.24,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585804 (US11530229, Compound 19) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:36.42,wD:27.29,1.0,(-10.75,-3.13,;-9.21,-3.13,;-8.44,-4.47,;-6.9,-4.47,;-6.13,-3.13,;-6.9,-1.8,;-6.13,-.47,;-4.59,-.47,;-3.82,.87,;-2.28,.87,;-1.25,2.01,;-1.57,3.52,;.16,1.39,;-0,-.15,;-1.51,-.47,;-2.28,-1.8,;-3.82,-1.8,;-1.51,-3.13,;-2.28,-4.47,;.03,-3.13,;-.74,-4.47,;1.49,2.16,;1.49,3.7,;2.82,4.47,;4.16,3.7,;4.16,2.16,;2.82,1.39,;5.49,1.39,;4.16,.62,;4.16,-.92,;2.91,-1.83,;3.39,-3.29,;4.93,-3.29,;5.4,-1.83,;6.87,-1.35,;6.58,.3,;7.67,1.39,;6.58,2.48,;9.21,1.39,;10.75,1.39,;-8.44,-1.8,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585805 (US11530229, Compound 20) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,27.29,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585806 (US11530229, Compound 21) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,27.29,wD:7.14,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585841 (US11530229, Compound 56) Show SMILES C[C@@H]1CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C2CC2)CCO1 |r,wU:29.34,wD:20.21,1.0,(-9.64,4.14,;-8.87,2.81,;-7.33,2.81,;-6.56,1.47,;-5.02,1.47,;-4.28,.14,;-5.05,-1.19,;-4.28,-2.53,;-2.74,-2.53,;-1.97,-1.19,;-2.74,.14,;-.43,-1.19,;.34,.14,;.34,-2.53,;1.88,-2.53,;2.65,-3.86,;4.19,-3.86,;4.96,-2.53,;4.19,-1.19,;2.65,-1.19,;4.96,.14,;5.73,-1.19,;7.27,-1.19,;8.17,.05,;9.64,-.42,;9.64,-1.96,;8.17,-2.44,;7.7,-3.9,;6.05,1.23,;4.96,2.32,;3.87,1.23,;4.96,3.86,;4.96,5.4,;-5.05,-3.86,;-6.39,-4.63,;-5.05,-5.4,;-7.33,.14,;-8.87,.14,;-9.64,1.47,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585804 (US11530229, Compound 19) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:36.42,wD:27.29,1.0,(-10.75,-3.13,;-9.21,-3.13,;-8.44,-4.47,;-6.9,-4.47,;-6.13,-3.13,;-6.9,-1.8,;-6.13,-.47,;-4.59,-.47,;-3.82,.87,;-2.28,.87,;-1.25,2.01,;-1.57,3.52,;.16,1.39,;-0,-.15,;-1.51,-.47,;-2.28,-1.8,;-3.82,-1.8,;-1.51,-3.13,;-2.28,-4.47,;.03,-3.13,;-.74,-4.47,;1.49,2.16,;1.49,3.7,;2.82,4.47,;4.16,3.7,;4.16,2.16,;2.82,1.39,;5.49,1.39,;4.16,.62,;4.16,-.92,;2.91,-1.83,;3.39,-3.29,;4.93,-3.29,;5.4,-1.83,;6.87,-1.35,;6.58,.3,;7.67,1.39,;6.58,2.48,;9.21,1.39,;10.75,1.39,;-8.44,-1.8,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585805 (US11530229, Compound 20) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,27.29,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585806 (US11530229, Compound 21) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN[C@@H]3CCC(F)(F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,27.29,wD:7.14,(7.67,-1.35,;6.2,-1.83,;5.73,-3.29,;4.19,-3.29,;3.71,-1.83,;4.96,-.92,;4.96,.62,;6.29,1.39,;7.38,.3,;8.47,1.39,;7.38,2.48,;10.01,1.39,;11.55,1.39,;4.96,2.16,;4.96,3.7,;3.62,4.47,;2.29,3.7,;2.29,2.16,;3.62,1.39,;.96,1.39,;.8,-.15,;-.71,-.47,;-1.48,.87,;-3.02,.87,;-3.79,-.47,;-5.33,-.47,;-6.1,-1.8,;-7.64,-1.8,;-8.55,-.55,;-10.01,-1.03,;-10.01,-2.57,;-11.55,-2.57,;-10.01,-4.11,;-8.55,-3.04,;-3.02,-1.8,;-1.48,-1.8,;-.71,-3.13,;-1.48,-4.47,;.83,-3.13,;.06,-4.47,;-.45,2.01,;-.77,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585841 (US11530229, Compound 56) Show SMILES C[C@@H]1CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C2CC2)CCO1 |r,wU:29.34,wD:20.21,1.0,(-9.64,4.14,;-8.87,2.81,;-7.33,2.81,;-6.56,1.47,;-5.02,1.47,;-4.28,.14,;-5.05,-1.19,;-4.28,-2.53,;-2.74,-2.53,;-1.97,-1.19,;-2.74,.14,;-.43,-1.19,;.34,.14,;.34,-2.53,;1.88,-2.53,;2.65,-3.86,;4.19,-3.86,;4.96,-2.53,;4.19,-1.19,;2.65,-1.19,;4.96,.14,;5.73,-1.19,;7.27,-1.19,;8.17,.05,;9.64,-.42,;9.64,-1.96,;8.17,-2.44,;7.7,-3.9,;6.05,1.23,;4.96,2.32,;3.87,1.23,;4.96,3.86,;4.96,5.4,;-5.05,-3.86,;-6.39,-4.63,;-5.05,-5.4,;-7.33,.14,;-8.87,.14,;-9.64,1.47,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585789 (US11530229, Compound 4) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCC4(CC4)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(6.71,-1.35,;5.24,-1.83,;4.76,-3.29,;3.22,-3.29,;2.75,-1.83,;3.99,-.92,;3.99,.62,;5.33,1.39,;6.42,.3,;7.51,1.39,;6.42,2.48,;9.05,1.39,;10.59,1.39,;3.99,2.16,;3.99,3.7,;2.66,4.47,;1.33,3.7,;1.33,2.16,;2.66,1.39,;-.01,1.39,;-.17,-.15,;-1.67,-.47,;-2.44,.87,;-3.98,.87,;-4.75,-.47,;-6.29,-.47,;-7.06,-1.8,;-6.59,-3.26,;-7.83,-4.17,;-9.08,-3.26,;-10.59,-2.94,;-10.11,-4.41,;-8.6,-1.8,;-3.98,-1.8,;-2.44,-1.8,;-1.67,-3.13,;-2.44,-4.47,;-.13,-3.13,;-.9,-4.47,;-1.41,2.01,;-1.73,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585796 (US11530229, Compound 11) Show SMILES C[C@@H]1CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)CCC1(F)F |r,wU:34.40,wD:25.27,1.0,(-10.75,-2.36,;-9.21,-2.36,;-8.44,-1.03,;-6.9,-1.03,;-6.13,.3,;-4.59,.3,;-3.82,1.64,;-2.28,1.64,;-1.25,2.78,;-1.57,4.29,;.16,2.16,;-0,.62,;-1.51,.3,;-2.28,-1.03,;-3.82,-1.03,;-1.51,-2.36,;-2.28,-3.7,;.03,-2.36,;-.74,-3.7,;1.49,2.93,;1.49,4.47,;2.82,5.24,;4.16,4.47,;4.16,2.93,;2.82,2.16,;5.49,2.16,;4.16,1.39,;4.16,-.15,;2.91,-1.06,;3.39,-2.52,;4.93,-2.52,;5.4,-1.06,;6.87,-.58,;6.58,1.07,;7.67,2.16,;6.58,3.25,;9.21,2.16,;10.75,2.16,;-6.13,-2.36,;-6.9,-3.7,;-8.44,-3.7,;-8.44,-5.24,;-9.77,-4.47,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585801 (US11530229, Compound 16) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCO[C@@H](C3)C(F)(F)F)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,30.35,(7.64,-1.35,;6.17,-1.83,;5.7,-3.29,;4.16,-3.29,;3.68,-1.83,;4.93,-.92,;4.93,.62,;6.26,1.39,;7.35,.3,;8.44,1.39,;7.35,2.48,;9.98,1.39,;11.52,1.39,;4.93,2.16,;4.93,3.7,;3.59,4.47,;2.26,3.7,;2.26,2.16,;3.59,1.39,;.93,1.39,;.77,-.15,;-.74,-.47,;-1.51,.87,;-3.05,.87,;-3.82,-.47,;-5.36,-.47,;-6.13,-1.8,;-5.36,-3.13,;-6.13,-4.47,;-7.67,-4.47,;-8.44,-3.13,;-7.67,-1.8,;-9.98,-3.13,;-10.75,-4.47,;-10.75,-1.8,;-11.52,-3.13,;-3.05,-1.8,;-1.51,-1.8,;-.74,-3.13,;-1.51,-4.47,;.8,-3.13,;.03,-4.47,;-.48,2.01,;-.8,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585802 (US11530229, Compound 17) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCCC(F)(F)CC3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(6.77,-.55,;5.31,-1.03,;4.83,-2.49,;3.29,-2.49,;2.81,-1.03,;4.06,-.12,;4.06,1.42,;5.39,2.19,;6.48,1.1,;7.57,2.19,;6.48,3.28,;9.11,2.19,;10.65,2.19,;4.06,2.96,;4.06,4.5,;2.73,5.27,;1.39,4.5,;1.39,2.96,;2.73,2.19,;.06,2.19,;-.1,.66,;-1.61,.34,;-2.38,1.67,;-3.92,1.67,;-4.69,.34,;-6.23,.34,;-7,-1,;-6.01,-2.21,;-6.36,-3.73,;-7.76,-4.41,;-9.16,-3.73,;-9.16,-5.27,;-10.65,-4.13,;-9.51,-2.21,;-8.54,-1,;-3.92,-1,;-2.38,-1,;-1.61,-2.33,;-2.38,-3.66,;-.07,-2.33,;-.84,-3.66,;-1.35,2.82,;-1.67,4.32,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585808 (US11530229, Compound 23) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CNC3CC4(CC4(F)F)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(8.14,-1.35,;6.67,-1.83,;6.2,-3.29,;4.66,-3.29,;4.18,-1.83,;5.43,-.92,;5.43,.62,;6.76,1.39,;7.85,.3,;8.94,1.39,;7.85,2.48,;10.48,1.39,;12.02,1.39,;5.43,2.16,;5.43,3.7,;4.09,4.47,;2.76,3.7,;2.76,2.16,;4.09,1.39,;1.43,1.39,;1.26,-.15,;-.24,-.47,;-1.01,.87,;-2.55,.87,;-3.32,-.47,;-4.86,-.47,;-5.63,-1.8,;-7.17,-1.8,;-8.26,-.71,;-9.35,-1.8,;-10.68,-2.57,;-10.68,-1.03,;-10.29,.46,;-12.02,-.26,;-8.26,-2.89,;-2.55,-1.8,;-1.01,-1.8,;-.24,-3.13,;-1.01,-4.47,;1.3,-3.13,;.53,-4.47,;.02,2.01,;-.3,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585796 (US11530229, Compound 11) Show SMILES C[C@@H]1CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)CCC1(F)F |r,wU:34.40,wD:25.27,1.0,(-10.75,-2.36,;-9.21,-2.36,;-8.44,-1.03,;-6.9,-1.03,;-6.13,.3,;-4.59,.3,;-3.82,1.64,;-2.28,1.64,;-1.25,2.78,;-1.57,4.29,;.16,2.16,;-0,.62,;-1.51,.3,;-2.28,-1.03,;-3.82,-1.03,;-1.51,-2.36,;-2.28,-3.7,;.03,-2.36,;-.74,-3.7,;1.49,2.93,;1.49,4.47,;2.82,5.24,;4.16,4.47,;4.16,2.93,;2.82,2.16,;5.49,2.16,;4.16,1.39,;4.16,-.15,;2.91,-1.06,;3.39,-2.52,;4.93,-2.52,;5.4,-1.06,;6.87,-.58,;6.58,1.07,;7.67,2.16,;6.58,3.25,;9.21,2.16,;10.75,2.16,;-6.13,-2.36,;-6.9,-3.7,;-8.44,-3.7,;-8.44,-5.24,;-9.77,-4.47,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585825 (US11530229, Compound 40) Show SMILES C[C@H]1CCCN(Cc2cc3C(=O)N(Cc3c(n2)C2CC2)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)C1 |r,wU:35.42,wD:26.29,1.0,(-10.74,-3.03,;-9.2,-3.03,;-8.43,-4.36,;-6.89,-4.36,;-6.12,-3.03,;-6.91,-1.7,;-6.14,-.36,;-4.6,-.36,;-3.83,.97,;-2.29,.97,;-1.26,2.12,;-1.58,3.62,;.15,1.49,;-.01,-.04,;-1.52,-.36,;-2.29,-1.7,;-3.83,-1.7,;-1.52,-3.03,;-1.52,-4.57,;-.18,-3.8,;1.48,2.26,;1.48,3.8,;2.82,4.57,;4.15,3.8,;4.15,2.26,;2.82,1.49,;5.48,1.49,;4.15,.72,;4.15,-.82,;2.9,-1.73,;3.38,-3.19,;4.92,-3.19,;5.4,-1.73,;6.86,-1.25,;6.57,.4,;7.66,1.49,;6.57,2.58,;9.2,1.49,;10.74,1.49,;-8.43,-1.7,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585829 (US11530229, Compound 44) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCOCC(CO)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(7.48,-1,;6.01,-1.48,;5.54,-2.94,;4,-2.94,;3.52,-1.48,;4.77,-.57,;4.77,.97,;6.1,1.74,;7.19,.65,;8.28,1.74,;7.19,2.83,;9.82,1.74,;11.36,1.74,;4.77,2.51,;4.77,4.05,;3.43,4.82,;2.1,4.05,;2.1,2.51,;3.43,1.74,;.77,1.74,;.6,.2,;-.9,-.12,;-1.67,1.22,;-3.21,1.22,;-3.98,-.12,;-5.52,-.12,;-6.29,-1.45,;-5.34,-2.66,;-5.7,-4.16,;-7.09,-4.82,;-8.47,-4.14,;-8.8,-2.63,;-10.3,-2.28,;-11.36,-3.4,;-7.83,-1.44,;-3.21,-1.45,;-1.67,-1.45,;-.9,-2.78,;-1.67,-4.12,;.64,-2.78,;-.13,-4.12,;-.64,2.36,;-.96,3.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585833 (US11530229, Compound 48) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCCCC(CO)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(7.48,-1,;6.01,-1.48,;5.54,-2.94,;4,-2.94,;3.52,-1.48,;4.77,-.57,;4.77,.97,;6.1,1.74,;7.19,.65,;8.28,1.74,;7.19,2.83,;9.82,1.74,;11.36,1.74,;4.77,2.51,;4.77,4.05,;3.43,4.82,;2.1,4.05,;2.1,2.51,;3.43,1.74,;.77,1.74,;.6,.2,;-.9,-.12,;-1.67,1.22,;-3.21,1.22,;-3.98,-.12,;-5.52,-.12,;-6.29,-1.45,;-5.34,-2.66,;-5.7,-4.16,;-7.09,-4.82,;-8.47,-4.14,;-8.8,-2.63,;-10.3,-2.28,;-11.36,-3.4,;-7.83,-1.44,;-3.21,-1.45,;-1.67,-1.45,;-.9,-2.78,;-1.67,-4.12,;.64,-2.78,;-.13,-4.12,;-.64,2.36,;-.96,3.87,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585773 (US11530229, Compound 1) Show SMILES Cc1cc(nc(n1)C1CC1)C(=O)Nc1cccc(c1)[C@@]1(Cc2nncn2C)C[C@@H](C1)C#N |r,wU:28.34,wD:19.21,(-8.63,1.82,;-7.3,1.05,;-5.96,1.82,;-4.63,1.05,;-4.63,-.49,;-5.96,-1.26,;-7.3,-.49,;-5.96,-2.8,;-6.73,-4.13,;-5.19,-4.13,;-3.3,1.82,;-3.3,3.36,;-1.96,1.05,;-.63,1.82,;-.63,3.36,;.71,4.13,;2.04,3.36,;2.04,1.82,;.71,1.05,;3.37,1.05,;2.04,.28,;2.04,-1.26,;.79,-2.16,;1.27,-3.63,;2.81,-3.63,;3.28,-2.16,;4.75,-1.69,;4.46,-.04,;5.55,1.05,;4.46,2.14,;7.09,1.05,;8.63,1.05,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585789 (US11530229, Compound 4) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCC4(CC4)C3)cc2C(F)(F)F)C1=O |r,wU:9.12,wD:7.14,(6.71,-1.35,;5.24,-1.83,;4.76,-3.29,;3.22,-3.29,;2.75,-1.83,;3.99,-.92,;3.99,.62,;5.33,1.39,;6.42,.3,;7.51,1.39,;6.42,2.48,;9.05,1.39,;10.59,1.39,;3.99,2.16,;3.99,3.7,;2.66,4.47,;1.33,3.7,;1.33,2.16,;2.66,1.39,;-.01,1.39,;-.17,-.15,;-1.67,-.47,;-2.44,.87,;-3.98,.87,;-4.75,-.47,;-6.29,-.47,;-7.06,-1.8,;-6.59,-3.26,;-7.83,-4.17,;-9.08,-3.26,;-10.59,-2.94,;-10.11,-4.41,;-8.6,-1.8,;-3.98,-1.8,;-2.44,-1.8,;-1.67,-3.13,;-2.44,-4.47,;-.13,-3.13,;-.9,-4.47,;-1.41,2.01,;-1.73,3.52,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM585824 (US11530229, Compound 39) Show SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CNC3CCC(F)(F)C3)nc2C2CC2)C1=O |r,wU:9.12,wD:7.14,(7.67,-1.25,;6.2,-1.73,;5.73,-3.19,;4.19,-3.19,;3.71,-1.73,;4.96,-.82,;4.96,.72,;6.29,1.49,;7.38,.4,;8.47,1.49,;7.38,2.58,;10.01,1.49,;11.55,1.49,;4.96,2.26,;4.96,3.8,;3.62,4.57,;2.29,3.8,;2.29,2.26,;3.62,1.49,;.96,1.49,;.8,-.04,;-.71,-.36,;-1.48,.97,;-3.02,.97,;-3.79,-.36,;-5.33,-.36,;-6.1,-1.7,;-7.64,-1.7,;-8.55,-.45,;-10.01,-.93,;-10.01,-2.47,;-11.55,-2.47,;-10.01,-4.01,;-8.55,-2.94,;-3.02,-1.7,;-1.48,-1.7,;-.71,-3.03,;-.71,-4.57,;.62,-3.8,;-.45,2.12,;-.77,3.62,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280CGT
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575634 (US11464802, Compound 3) Show SMILES C[C@@H]1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575635 (US11464802, Compound 4) Show SMILES Cn1cnnc1CC1(COC1)c1cccc(c1)N1Cc2c(cc(CN3CCCC(CC#N)C3)cc2C(F)(F)F)C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair
Isoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))	BDBM575642 (US11464802, Compound 11) Show SMILES Cn1cnnc1CC1(COC1)c1cccc(c1)N1Cc2c(cc(CN3CCC(F)(F)[C@@H](C3)C#N)cc2C(F)(F)F)C1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V98CBJ
					More data for this Ligand-Target Pair

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