Compile Data Set for Download or QSAR

Found 24 hits with Last Name = 'betari' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50130725 (3-(3-Chloro-4-hydroxy-phenylamino)-4-(2-nitro-phen...) Show SMILES Oc1ccc(NC2=C(C(=O)NC2=O)c2ccccc2[N+]([O-])=O)cc1Cl |t:6| Show InChI InChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501616 (CHEMBL4084089) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCNCCCN)c3=O Show InChI InChI=1S/C31H35N5O5/c1-41-25-8-3-2-7-20(25)19-34-16-6-18-36-30(39)23-11-9-21-26-22(10-12-24(27(23)26)31(36)40)29(38)35(28(21)37)17-5-15-33-14-4-13-32/h2-3,7-12,33-34H,4-6,13-19,32H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501615 (CHEMBL4091846) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCNCCCCNCCCN)c3=O Show InChI InChI=1S/C35H44N6O5/c1-46-29-10-3-2-9-24(29)23-39-20-8-22-41-34(44)27-13-11-25-30-26(12-14-28(31(27)30)35(41)45)33(43)40(32(25)42)21-7-19-38-17-5-4-16-37-18-6-15-36/h2-3,9-14,37-39H,4-8,15-23,36H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50535403 (CHEMBL4590543) Show SMILES ONC(=O)CCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C13H14N4O4S/c18-10(17-21)2-1-5-14-13(22)15-7-3-4-8-9(6-7)12(20)16-11(8)19/h3-4,6,21H,1-2,5H2,(H,17,18)(H2,14,15,22)(H,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50535402 (CHEMBL4449010) Show SMILES ONC(=O)CCCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C15H18N4O4S/c20-12(19-23)4-2-1-3-7-16-15(24)17-9-5-6-10-11(8-9)14(22)18-13(10)21/h5-6,8,23H,1-4,7H2,(H,19,20)(H2,16,17,24)(H,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50535402 (CHEMBL4449010) Show SMILES ONC(=O)CCCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C15H18N4O4S/c20-12(19-23)4-2-1-3-7-16-15(24)17-9-5-6-10-11(8-9)14(22)18-13(10)21/h5-6,8,23H,1-4,7H2,(H,19,20)(H2,16,17,24)(H,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC6 expressed in baculovirus infected Sf6 insect cells using batcp as substrate incubated for 1 hr by fl...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50535401 (CHEMBL4443876) Show SMILES ONC(=O)CCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C12H12N4O4S/c17-9(16-20)3-4-13-12(21)14-6-1-2-7-8(5-6)11(19)15-10(7)18/h1-2,5,20H,3-4H2,(H,16,17)(H2,13,14,21)(H,15,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50535400 (CHEMBL4575045) Show SMILES ONC(=O)CCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C14H16N4O4S/c19-11(18-22)3-1-2-6-15-14(23)16-8-4-5-9-10(7-8)13(21)17-12(9)20/h4-5,7,22H,1-3,6H2,(H,18,19)(H2,15,16,23)(H,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50535400 (CHEMBL4575045) Show SMILES ONC(=O)CCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C14H16N4O4S/c19-11(18-22)3-1-2-6-15-14(23)16-8-4-5-9-10(7-8)13(21)17-12(9)20/h4-5,7,22H,1-3,6H2,(H,18,19)(H2,15,16,23)(H,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501619 (CHEMBL4084827) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCOCCCCOCCCN)c3=O Show InChI InChI=1S/C35H42N4O7/c1-44-29-10-3-2-9-24(29)23-37-16-7-17-38-32(40)25-11-13-27-31-28(14-12-26(30(25)31)33(38)41)35(43)39(34(27)42)18-8-22-46-20-5-4-19-45-21-6-15-36/h2-3,9-14,37H,4-8,15-23,36H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501614 (CHEMBL583073) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCNCc1ccccc1OC)c3=O Show InChI InChI=1S/C36H36N4O6/c1-45-29-11-5-3-9-23(29)21-37-17-7-19-39-33(41)25-13-15-27-32-28(16-14-26(31(25)32)34(39)42)36(44)40(35(27)43)20-8-18-38-22-24-10-4-6-12-30(24)46-2/h3-6,9-16,37-38H,7-8,17-22H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501618 (CHEMBL4064888) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCCNCCCN)c3=O Show InChI InChI=1S/C32H37N5O5/c1-42-26-9-3-2-8-21(26)20-35-17-7-19-37-31(40)24-12-10-22-27-23(11-13-25(28(24)27)32(37)41)30(39)36(29(22)38)18-5-4-15-34-16-6-14-33/h2-3,8-13,34-35H,4-7,14-20,33H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50501617 (CHEMBL4092588) Show SMILES COc1ccccc1CNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCNCCCCN)c3=O Show InChI InChI=1S/C32H37N5O5/c1-42-26-9-3-2-8-21(26)20-35-17-7-19-37-31(40)24-12-10-22-27-23(11-13-25(28(24)27)32(37)41)30(39)36(29(22)38)18-6-16-34-15-5-4-14-33/h2-3,8-13,34-35H,4-7,14-20,33H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...				Eur J Med Chem 128: 107-122 (2017) Article DOI: 10.1016/j.ejmech.2017.01.025 BindingDB Entry DOI: 10.7270/Q2668H7X
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50535403 (CHEMBL4590543) Show SMILES ONC(=O)CCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C13H14N4O4S/c18-10(17-21)2-1-5-14-13(22)15-7-3-4-8-9(6-7)12(20)16-11(8)19/h3-4,6,21H,1-2,5H2,(H,17,18)(H2,14,15,22)(H,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50535403 (CHEMBL4590543) Show SMILES ONC(=O)CCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C13H14N4O4S/c18-10(17-21)2-1-5-14-13(22)15-7-3-4-8-9(6-7)12(20)16-11(8)19/h3-4,6,21H,1-2,5H2,(H,17,18)(H2,14,15,22)(H,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC6 expressed in baculovirus infected Sf6 insect cells using batcp as substrate incubated for 1 hr by fl...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50535402 (CHEMBL4449010) Show SMILES ONC(=O)CCCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C15H18N4O4S/c20-12(19-23)4-2-1-3-7-16-15(24)17-9-5-6-10-11(8-9)14(22)18-13(10)21/h5-6,8,23H,1-4,7H2,(H,19,20)(H2,16,17,24)(H,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50535400 (CHEMBL4575045) Show SMILES ONC(=O)CCCCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C14H16N4O4S/c19-11(18-22)3-1-2-6-15-14(23)16-8-4-5-9-10(7-8)13(21)17-12(9)20/h4-5,7,22H,1-3,6H2,(H,18,19)(H2,15,16,23)(H,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC6 expressed in baculovirus infected Sf6 insect cells using batcp as substrate incubated for 1 hr by fl...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50535401 (CHEMBL4443876) Show SMILES ONC(=O)CCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C12H12N4O4S/c17-9(16-20)3-4-13-12(21)14-6-1-2-7-8(5-6)11(19)15-10(7)18/h1-2,5,20H,3-4H2,(H,16,17)(H2,13,14,21)(H,15,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant his tagged HDAC6 expressed in baculovirus infected Sf6 insect cells using batcp as substrate incubated for 1 hr by fl...				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50535401 (CHEMBL4443876) Show SMILES ONC(=O)CCNC(=S)Nc1ccc2C(=O)NC(=O)c2c1 Show InChI InChI=1S/C12H12N4O4S/c17-9(16-20)3-4-13-12(21)14-6-1-2-7-8(5-6)11(19)15-10(7)18/h1-2,5,20H,3-4H2,(H,16,17)(H2,13,14,21)(H,15,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50350644 (PHTHALIMIDE) Show SMILES O=C1NC(=O)c2ccccc12 Show InChI InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay				ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50555892 (CHEMBL4745205) Show SMILES CN(C)CCNc1cccc-2c1C(=O)c1nc3ccccc3c(=O)n-21 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112504 BindingDB Entry DOI: 10.7270/Q2VT1WRN
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)c2cc3OCOc3cc12 |r| Show InChI InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112504 BindingDB Entry DOI: 10.7270/Q2VT1WRN
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50555891 (CHEMBL4756707) Show SMILES CN1CCN(CC1)c1cccc-2c1C(=O)c1nc3ccccc3c(=O)n-21 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112504 BindingDB Entry DOI: 10.7270/Q2VT1WRN
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50555893 (CHEMBL4747945) Show SMILES CN1CCN(CC1)c1ccc2C(=O)c3nc4ccccc4c(=O)n3-c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112504 BindingDB Entry DOI: 10.7270/Q2VT1WRN
					More data for this Ligand-Target Pair