Compile Data Set for Download or QSAR

Found 110 hits with Last Name = 'beveridge' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP1A2 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C9 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes assessed as reduction in testosterone 6beta-hydroxylation activity by high-pressure liquid chromatogra...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2D6 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50566354 (CHEMBL4853103) Show SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-ta...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00044 BindingDB Entry DOI: 10.7270/Q2MG7T86
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513079 (CHEMBL4583846) Show SMILES COc1ccc(NC(=O)Cn2nc(C)cc(Cc3ccccc3OC)c2=O)cc1 Show InChI InChI=1S/C22H23N3O4/c1-15-12-17(13-16-6-4-5-7-20(16)29-3)22(27)25(24-15)14-21(26)23-18-8-10-19(28-2)11-9-18/h4-12H,13-14H2,1-3H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513080 (CHEMBL4453208) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3c(F)cc(Cl)cc3F)c2=O)c1 Show InChI InChI=1S/C21H18ClF2N3O3/c1-12-6-14(7-13-4-3-5-16(8-13)30-2)21(29)27(26-12)11-19(28)25-20-17(23)9-15(22)10-18(20)24/h3-6,8-10H,7,11H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513081 (CHEMBL4556579) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(cc(Cc2ccccc2OC)c1=O)C(F)(F)F Show InChI InChI=1S/C25H25ClF3N3O3/c1-3-4-8-20(23(33)30-19-12-10-18(26)11-13-19)32-24(34)17(15-22(31-32)25(27,28)29)14-16-7-5-6-9-21(16)35-2/h5-7,9-13,15,20H,3-4,8,14H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513082 (CHEMBL4440569) Show SMILES COc1ccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccc(Br)cc3)c2=O)cc1 Show InChI InChI=1S/C22H22BrN3O3/c1-14-12-17(13-16-4-10-20(29-3)11-5-16)22(28)26(25-14)15(2)21(27)24-19-8-6-18(23)7-9-19/h4-12,15H,13H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513083 (CHEMBL4551649) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2)c1=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-9-23(24(30)27-21-12-10-20(26)11-13-21)29-25(31)19(14-17(2)28-29)15-18-7-6-8-22(16-18)32-3/h6-8,10-14,16,23H,4-5,9,15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513084 (CHEMBL4472897) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2F)c1=O Show InChI InChI=1S/C21H19ClFN3O3/c1-13-9-15(10-14-5-3-4-6-19(14)29-2)21(28)26(25-13)12-20(27)24-18-8-7-16(22)11-17(18)23/h3-9,11H,10,12H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513085 (CHEMBL4454594) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513086 (CHEMBL4452950) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(Cl)cc3F)c2=O)c1 Show InChI InChI=1S/C21H19ClFN3O3/c1-13-8-15(9-14-4-3-5-17(10-14)29-2)21(28)26(25-13)12-20(27)24-19-7-6-16(22)11-18(19)23/h3-8,10-11H,9,12H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513087 (CHEMBL4568124) Show SMILES Cc1cc(Cc2ccc(F)cc2)c(=O)n(CC(=O)Nc2ccc(Br)cc2[N+]([O-])=O)n1 Show InChI InChI=1S/C20H16BrFN4O4/c1-12-8-14(9-13-2-5-16(22)6-3-13)20(28)25(24-12)11-19(27)23-17-7-4-15(21)10-18(17)26(29)30/h2-8,10H,9,11H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513088 (CHEMBL4560787) Show SMILES Cc1cc(Cc2ccc(F)cc2)c(=O)n(CC(=O)Nc2c(F)cc(F)cc2[N+]([O-])=O)n1 Show InChI InChI=1S/C20H15F3N4O4/c1-11-6-13(7-12-2-4-14(21)5-3-12)20(29)26(25-11)10-18(28)24-19-16(23)8-15(22)9-17(19)27(30)31/h2-6,8-9H,7,10H2,1H3,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513089 (CHEMBL4447632) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(Cl)cc3)c2=O)c1OC Show InChI InChI=1S/C22H22ClN3O4/c1-14-11-16(12-15-5-4-6-19(29-2)21(15)30-3)22(28)26(25-14)13-20(27)24-18-9-7-17(23)8-10-18/h4-11H,12-13H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513090 (CHEMBL4447830) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccc(Cl)cc3)c2=O)c1OC Show InChI InChI=1S/C23H24ClN3O4/c1-14-12-17(13-16-6-5-7-20(30-3)21(16)31-4)23(29)27(26-14)15(2)22(28)25-19-10-8-18(24)9-11-19/h5-12,15H,13H2,1-4H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	145	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513091 (CHEMBL4517103) Show SMILES CCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C23H24ClN3O3/c1-4-20(22(28)25-19-11-9-18(24)10-12-19)27-23(29)17(13-15(2)26-27)14-16-7-5-6-8-21(16)30-3/h5-13,20H,4,14H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513092 (CHEMBL4440250) Show SMILES COc1ccccc1Cc1cc(C)nn(C(C(C)C)C(=O)Nc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H26ClN3O3/c1-15(2)22(23(29)26-20-11-9-19(25)10-12-20)28-24(30)18(13-16(3)27-28)14-17-7-5-6-8-21(17)31-4/h5-13,15,22H,14H2,1-4H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513093 (CHEMBL4581644) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28BrN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	331	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513094 (CHEMBL4448213) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2cccc(OC)c2)c1=O Show InChI InChI=1S/C25H28BrN3O3/c1-4-5-9-23(24(30)27-21-12-10-20(26)11-13-21)29-25(31)19(14-17(2)28-29)15-18-7-6-8-22(16-18)32-3/h6-8,10-14,16,23H,4-5,9,15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513095 (CHEMBL4532583) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30BrN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	245	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513096 (CHEMBL4459219) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2cccc(Cl)c2)c1=O Show InChI InChI=1S/C21H20ClN3O3/c1-14-10-16(11-15-6-3-4-9-19(15)28-2)21(27)25(24-14)13-20(26)23-18-8-5-7-17(22)12-18/h3-10,12H,11,13H2,1-2H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513097 (CHEMBL4536766) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C21H20ClN3O3/c1-14-11-16(12-15-5-3-4-6-19(15)28-2)21(27)25(24-14)13-20(26)23-18-9-7-17(22)8-10-18/h3-11H,12-13H2,1-2H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513098 (CHEMBL4581717) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccccc2C#N)c1=O Show InChI InChI=1S/C22H20N4O3/c1-15-11-18(12-16-7-4-6-10-20(16)29-2)22(28)26(25-15)14-21(27)24-19-9-5-3-8-17(19)13-23/h3-11H,12,14H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513099 (CHEMBL4581435) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccc(cc2)C#N)c1=O Show InChI InChI=1S/C22H20N4O3/c1-15-11-18(12-17-5-3-4-6-20(17)29-2)22(28)26(25-15)14-21(27)24-19-9-7-16(13-23)8-10-19/h3-11H,12,14H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513079 (CHEMBL4583846) Show SMILES COc1ccc(NC(=O)Cn2nc(C)cc(Cc3ccccc3OC)c2=O)cc1 Show InChI InChI=1S/C22H23N3O4/c1-15-12-17(13-16-6-4-5-7-20(16)29-3)22(27)25(24-15)14-21(26)23-18-8-10-19(28-2)11-9-18/h4-12H,13-14H2,1-3H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513100 (CHEMBL4457243) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2Cl)c1=O Show InChI InChI=1S/C21H19Cl2N3O3/c1-13-9-15(10-14-5-3-4-6-19(14)29-2)21(28)26(25-13)12-20(27)24-18-8-7-16(22)11-17(18)23/h3-9,11H,10,12H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513101 (CHEMBL4571633) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2c(F)cc(Cl)cc2F)c1=O Show InChI InChI=1S/C21H18ClF2N3O3/c1-12-7-14(8-13-5-3-4-6-18(13)30-2)21(29)27(26-12)11-19(28)25-20-16(23)9-15(22)10-17(20)24/h3-7,9-10H,8,11H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50295524 (CHEMBL551589 | N-(4-Bromophenyl)-2-[5-(3-methoxybe...) Show SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)c1 Show InChI InChI=1S/C21H20BrN3O3/c1-14-10-16(11-15-4-3-5-19(12-15)28-2)21(27)25(24-14)13-20(26)23-18-8-6-17(22)7-9-18/h3-10,12H,11,13H2,1-2H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513102 (CHEMBL4448576) Show SMILES CC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2ccccc2F)c1=O Show InChI InChI=1S/C21H19BrFN3O2/c1-13-11-16(12-15-5-3-4-6-19(15)23)21(28)26(25-13)14(2)20(27)24-18-9-7-17(22)8-10-18/h3-11,14H,12H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513103 (CHEMBL4447184) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccccc3Cl)c2=O)c1 Show InChI InChI=1S/C22H22ClN3O3/c1-14-11-17(12-16-7-6-8-18(13-16)29-3)22(28)26(25-14)15(2)21(27)24-20-10-5-4-9-19(20)23/h4-11,13,15H,12H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513104 (CHEMBL4456812) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccccc3F)c2=O)c1 Show InChI InChI=1S/C22H22FN3O3/c1-14-11-17(12-16-7-6-8-18(13-16)29-3)22(28)26(25-14)15(2)21(27)24-20-10-5-4-9-19(20)23/h4-11,13,15H,12H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513105 (CHEMBL4473444) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3cccc(F)c3)c2=O)c1 Show InChI InChI=1S/C22H22FN3O3/c1-14-10-17(11-16-6-4-9-20(12-16)29-3)22(28)26(25-14)15(2)21(27)24-19-8-5-7-18(23)13-19/h4-10,12-13,15H,11H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513106 (CHEMBL4543016) Show SMILES CC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2cccc(F)c2)c1=O Show InChI InChI=1S/C21H19BrFN3O2/c1-13-10-16(11-15-4-3-5-18(23)12-15)21(28)26(25-13)14(2)20(27)24-19-8-6-17(22)7-9-19/h3-10,12,14H,11H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513107 (CHEMBL4436651) Show SMILES CC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C21H19BrFN3O2/c1-13-11-16(12-15-3-7-18(23)8-4-15)21(28)26(25-13)14(2)20(27)24-19-9-5-17(22)6-10-19/h3-11,14H,12H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513088 (CHEMBL4560787) Show SMILES Cc1cc(Cc2ccc(F)cc2)c(=O)n(CC(=O)Nc2c(F)cc(F)cc2[N+]([O-])=O)n1 Show InChI InChI=1S/C20H15F3N4O4/c1-11-6-13(7-12-2-4-14(21)5-3-12)20(29)26(25-11)10-18(28)24-19-16(23)8-15(22)9-17(19)27(30)31/h2-6,8-9H,7,10H2,1H3,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513108 (CHEMBL4549250) Show SMILES COc1ccc(OC)c(Cc2cc(C)nn(CC(=O)Nc3ccc(Cl)cc3)c2=O)c1 Show InChI InChI=1S/C22H22ClN3O4/c1-14-10-16(11-15-12-19(29-2)8-9-20(15)30-3)22(28)26(25-14)13-21(27)24-18-6-4-17(23)5-7-18/h4-10,12H,11,13H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513091 (CHEMBL4517103) Show SMILES CCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C23H24ClN3O3/c1-4-20(22(28)25-19-11-9-18(24)10-12-19)27-23(29)17(13-15(2)26-27)14-16-7-5-6-8-21(16)30-3/h5-13,20H,4,14H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513093 (CHEMBL4581644) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28BrN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513085 (CHEMBL4454594) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	891	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513094 (CHEMBL4448213) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2cccc(OC)c2)c1=O Show InChI InChI=1S/C25H28BrN3O3/c1-4-5-9-23(24(30)27-21-12-10-20(26)11-13-21)29-25(31)19(14-17(2)28-29)15-18-7-6-8-22(16-18)32-3/h6-8,10-14,16,23H,4-5,9,15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513095 (CHEMBL4532583) Show SMILES CCCCC(C(=O)Nc1ccc(Br)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30BrN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50513085 (CHEMBL4454594) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21692 (1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair				3D Structure (crystal)
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513085 (CHEMBL4454594) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-9-22(24(30)27-21-13-11-20(26)12-14-21)29-25(31)19(15-17(2)28-29)16-18-8-6-7-10-23(18)32-3/h6-8,10-15,22H,4-5,9,16H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	891	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513098 (CHEMBL4581717) Show SMILES COc1ccccc1Cc1cc(C)nn(CC(=O)Nc2ccccc2C#N)c1=O Show InChI InChI=1S/C22H20N4O3/c1-15-11-18(12-16-7-4-6-10-20(16)29-2)22(28)26(25-15)14-21(27)24-19-9-5-3-8-17(19)13-23/h3-11H,12,14H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair

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