Compile Data Set for Download or QSAR

Found 104 hits with Last Name = 'black-schaefer' and Initial = 'cl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201303 (1-(4-(4-amino-7-(pyrimidin-5-yl)thieno[3,2-c]pyrid...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2cncnc2)c1 Show InChI InChI=1S/C25H20N6OS/c1-15-3-2-4-19(9-15)31-25(32)30-18-7-5-16(6-8-18)21-13-33-23-20(12-29-24(26)22(21)23)17-10-27-14-28-11-17/h2-14H,1H3,(H2,26,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201330 (1-(4-(4-amino-7-(pyridin-4-yl)thieno[3,2-c]pyridin...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccncc2)c1 Show InChI InChI=1S/C26H21N5OS/c1-16-3-2-4-20(13-16)31-26(32)30-19-7-5-17(6-8-19)22-15-33-24-21(14-29-25(27)23(22)24)18-9-11-28-12-10-18/h2-15H,1H3,(H2,27,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201323 (1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2cccnc2)c1 Show InChI InChI=1S/C26H21N5OS/c1-16-4-2-6-20(12-16)31-26(32)30-19-9-7-17(8-10-19)22-15-33-24-21(14-29-25(27)23(22)24)18-5-3-11-28-13-18/h2-15H,1H3,(H2,27,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201330 (1-(4-(4-amino-7-(pyridin-4-yl)thieno[3,2-c]pyridin...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccncc2)c1 Show InChI InChI=1S/C26H21N5OS/c1-16-3-2-4-20(13-16)31-26(32)30-19-7-5-17(6-8-19)22-15-33-24-21(14-29-25(27)23(22)24)18-9-11-28-12-10-18/h2-15H,1H3,(H2,27,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201303 (1-(4-(4-amino-7-(pyrimidin-5-yl)thieno[3,2-c]pyrid...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2cncnc2)c1 Show InChI InChI=1S/C25H20N6OS/c1-15-3-2-4-19(9-15)31-25(32)30-18-7-5-16(6-8-18)21-13-33-23-20(12-29-24(26)22(21)23)17-10-27-14-28-11-17/h2-14H,1H3,(H2,26,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201307 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C21H18N4OS/c1-13-3-2-4-16(11-13)25-21(26)24-15-7-5-14(6-8-15)17-12-27-18-9-10-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201323 (1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2cccnc2)c1 Show InChI InChI=1S/C26H21N5OS/c1-16-4-2-6-20(12-16)31-26(32)30-19-9-7-17(8-10-19)22-15-33-24-21(14-29-25(27)23(22)24)18-5-3-11-28-13-18/h2-15H,1H3,(H2,27,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201314 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)cc1C Show InChI InChI=1S/C22H20N4OS/c1-13-3-6-17(11-14(13)2)26-22(27)25-16-7-4-15(5-8-16)18-12-28-19-9-10-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201319 (1-(4-(4-amino-7-(3-(methylcarbamoyl)phenyl)thieno[...) Show SMILES CNC(=O)c1cccc(c1)-c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C29H25N5O2S/c1-17-5-3-8-22(13-17)34-29(36)33-21-11-9-18(10-12-21)24-16-37-26-23(15-32-27(30)25(24)26)19-6-4-7-20(14-19)28(35)31-2/h3-16H,1-2H3,(H2,30,32)(H,31,35)(H2,33,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201327 (1-(4-(4-amino-7-(4-hydroxyphenyl)thieno[3,2-c]pyri...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccc(O)cc2)c1 Show InChI InChI=1S/C27H22N4O2S/c1-16-3-2-4-20(13-16)31-27(33)30-19-9-5-18(6-10-19)23-15-34-25-22(14-29-26(28)24(23)25)17-7-11-21(32)12-8-17/h2-15,32H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201302 (1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201318 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 Show InChI InChI=1S/C20H15FN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201308 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C24H18N4OS/c25-23-22-20(14-30-21(22)11-12-26-23)16-6-8-18(9-7-16)27-24(29)28-19-10-5-15-3-1-2-4-17(15)13-19/h1-14H,(H2,25,26)(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201320 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-13-9-14(2)11-17(10-13)26-22(27)25-16-5-3-15(4-6-16)18-12-28-19-7-8-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201308 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C24H18N4OS/c25-23-22-20(14-30-21(22)11-12-26-23)16-6-8-18(9-7-16)27-24(29)28-19-10-5-15-3-1-2-4-17(15)13-19/h1-14H,(H2,25,26)(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201311 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12 Show InChI InChI=1S/C20H15ClN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137758 (2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...) Show SMILES Oc1ccc(cc1)C1CCc2c(C1)sc(NC(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1)c2C#N Show InChI InChI=1S/C26H23Cl2N3O5S2/c27-21-13-22(28)24(38(34,35)31-7-9-36-10-8-31)12-19(21)25(33)30-26-20(14-29)18-6-3-16(11-23(18)37-26)15-1-4-17(32)5-2-15/h1-2,4-5,12-13,16,32H,3,6-11H2,(H,30,33)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.				Bioorg Med Chem Lett 14: 267-70 (2003) BindingDB Entry DOI: 10.7270/Q2R49Q55
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137758 (2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...) Show SMILES Oc1ccc(cc1)C1CCc2c(C1)sc(NC(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1)c2C#N Show InChI InChI=1S/C26H23Cl2N3O5S2/c27-21-13-22(28)24(38(34,35)31-7-9-36-10-8-31)12-19(21)25(33)30-26-20(14-29)18-6-3-16(11-23(18)37-26)15-1-4-17(32)5-2-15/h1-2,4-5,12-13,16,32H,3,6-11H2,(H,30,33)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.				Chem Biol Drug Des 67: 58-65 (2006) Article DOI: 10.1111/j.1747-0285.2005.00317.x BindingDB Entry DOI: 10.7270/Q2GF0S0Z
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201328 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-1-m...) Show SMILES CN(C(=O)Nc1cccc(C)c1)c1ccc(cc1)-c1csc2ccnc(N)c12 Show InChI InChI=1S/C22H20N4OS/c1-14-4-3-5-16(12-14)25-22(27)26(2)17-8-6-15(7-9-17)18-13-28-19-10-11-24-21(23)20(18)19/h3-13H,1-2H3,(H2,23,24)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201310 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-2-14-4-3-5-17(12-14)26-22(27)25-16-8-6-15(7-9-16)18-13-28-19-10-11-24-21(23)20(18)19/h3-13H,2H2,1H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201322 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)cc1 Show InChI InChI=1S/C21H18N4OS/c1-13-2-6-15(7-3-13)24-21(26)25-16-8-4-14(5-9-16)17-12-27-18-10-11-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201325 (1-(4-(4-amino-2-methylthieno[3,2-c]pyridin-3-yl)ph...) Show SMILES Cc1sc2ccnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C22H20N4OS/c1-13-4-3-5-17(12-13)26-22(27)25-16-8-6-15(7-9-16)19-14(2)28-18-10-11-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201327 (1-(4-(4-amino-7-(4-hydroxyphenyl)thieno[3,2-c]pyri...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccc(O)cc2)c1 Show InChI InChI=1S/C27H22N4O2S/c1-16-3-2-4-20(13-16)31-27(33)30-19-9-5-18(6-10-19)23-15-34-25-22(14-29-26(28)24(23)25)17-7-11-21(32)12-8-17/h2-15,32H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201309 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccs4)cc3)c12 Show InChI InChI=1S/C18H14N4OS2/c19-17-16-13(10-25-14(16)7-8-20-17)11-3-5-12(6-4-11)21-18(23)22-15-2-1-9-24-15/h1-10H,(H2,19,20)(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201310 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-2-14-4-3-5-17(12-14)26-22(27)25-16-8-6-15(7-9-16)18-13-28-19-10-11-24-21(23)20(18)19/h3-13H,2H2,1H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201307 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C21H18N4OS/c1-13-3-2-4-16(11-13)25-21(26)24-15-7-5-14(6-8-15)17-12-27-18-9-10-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201302 (1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201301 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccsc4)cc3)c12 Show InChI InChI=1S/C18H14N4OS2/c19-17-16-14(10-25-15(16)5-7-20-17)11-1-3-12(4-2-11)21-18(23)22-13-6-8-24-9-13/h1-10H,(H2,19,20)(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201314 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)cc1C Show InChI InChI=1S/C22H20N4OS/c1-13-3-6-17(11-14(13)2)26-22(27)25-16-7-4-15(5-8-16)18-12-28-19-9-10-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201305 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(c4)C#N)cc3)c12 Show InChI InChI=1S/C21H15N5OS/c22-11-13-2-1-3-16(10-13)26-21(27)25-15-6-4-14(5-7-15)17-12-28-18-8-9-24-20(23)19(17)18/h1-10,12H,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201320 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-13-9-14(2)11-17(10-13)26-22(27)25-16-5-3-15(4-6-16)18-12-28-19-7-8-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201309 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccs4)cc3)c12 Show InChI InChI=1S/C18H14N4OS2/c19-17-16-13(10-25-14(16)7-8-20-17)11-3-5-12(6-4-11)21-18(23)22-15-2-1-9-24-15/h1-10H,(H2,19,20)(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137762 (2-Chloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6,7-t...) Show SMILES CCN(CC)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)Nc1sc2CC(CCc2c1C#N)c1ccc(O)cc1 Show InChI InChI=1S/C26H26ClN3O4S2/c1-3-30(4-2)36(33,34)19-10-12-23(27)21(14-19)25(32)29-26-22(15-28)20-11-7-17(13-24(20)35-26)16-5-8-18(31)9-6-16/h5-6,8-10,12,14,17,31H,3-4,7,11,13H2,1-2H3,(H,29,32)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.				Bioorg Med Chem Lett 14: 267-70 (2003) BindingDB Entry DOI: 10.7270/Q2R49Q55
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201311 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12 Show InChI InChI=1S/C20H15ClN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201319 (1-(4-(4-amino-7-(3-(methylcarbamoyl)phenyl)thieno[...) Show SMILES CNC(=O)c1cccc(c1)-c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C29H25N5O2S/c1-17-5-3-8-22(13-17)34-29(36)33-21-11-9-18(10-12-21)24-16-37-26-23(15-32-27(30)25(24)26)19-6-4-7-20(14-19)28(35)31-2/h3-16H,1-2H3,(H2,30,32)(H,31,35)(H2,33,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201317 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 Show InChI InChI=1S/C20H16N4OS/c21-19-18-16(12-26-17(18)10-11-22-19)13-6-8-15(9-7-13)24-20(25)23-14-4-2-1-3-5-14/h1-12H,(H2,21,22)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201301 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccsc4)cc3)c12 Show InChI InChI=1S/C18H14N4OS2/c19-17-16-14(10-25-15(16)5-7-20-17)11-1-3-12(4-2-11)21-18(23)22-13-6-8-24-9-13/h1-10H,(H2,19,20)(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137786 (2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...) Show SMILES CCN(CC)S(=O)(=O)c1cc(C(=O)Nc2sc3CC(CCc3c2C#N)c2ccc(O)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C26H25Cl2N3O4S2/c1-3-31(4-2)37(34,35)24-12-19(21(27)13-22(24)28)25(33)30-26-20(14-29)18-10-7-16(11-23(18)36-26)15-5-8-17(32)9-6-15/h5-6,8-9,12-13,16,32H,3-4,7,10-11H2,1-2H3,(H,30,33)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.				Bioorg Med Chem Lett 14: 267-70 (2003) BindingDB Entry DOI: 10.7270/Q2R49Q55
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137786 (2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...) Show SMILES CCN(CC)S(=O)(=O)c1cc(C(=O)Nc2sc3CC(CCc3c2C#N)c2ccc(O)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C26H25Cl2N3O4S2/c1-3-31(4-2)37(34,35)24-12-19(21(27)13-22(24)28)25(33)30-26-20(14-29)18-10-7-16(11-23(18)36-26)15-5-8-17(32)9-6-15/h5-6,8-9,12-13,16,32H,3-4,7,10-11H2,1-2H3,(H,30,33)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.				Chem Biol Drug Des 67: 58-65 (2006) Article DOI: 10.1111/j.1747-0285.2005.00317.x BindingDB Entry DOI: 10.7270/Q2GF0S0Z
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137768 (2,4-Dichloro-N-(3-cyano-6-phenyl-4,5,6,7-tetrahydr...) Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1sc2CC(CCc2c1C#N)c1ccccc1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C26H23Cl2N3O4S2/c27-21-14-22(28)24(37(33,34)31-8-10-35-11-9-31)13-19(21)25(32)30-26-20(15-29)18-7-6-17(12-23(18)36-26)16-4-2-1-3-5-16/h1-5,13-14,17H,6-12H2,(H,30,32)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.				Bioorg Med Chem Lett 14: 267-70 (2003) BindingDB Entry DOI: 10.7270/Q2R49Q55
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201317 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 Show InChI InChI=1S/C20H16N4OS/c21-19-18-16(12-26-17(18)10-11-22-19)13-6-8-15(9-7-13)24-20(25)23-14-4-2-1-3-5-14/h1-12H,(H2,21,22)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201304 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc5ccccc45)cc3)c12 Show InChI InChI=1S/C24H18N4OS/c25-23-22-19(14-30-21(22)12-13-26-23)16-8-10-17(11-9-16)27-24(29)28-20-7-3-5-15-4-1-2-6-18(15)20/h1-14H,(H2,25,26)(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201315 (2-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-N-m...) Show SMILES Cc1cccc(NC(=O)Cc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H19N3OS/c1-14-3-2-4-17(11-14)25-20(26)12-15-5-7-16(8-6-15)18-13-27-19-9-10-24-22(23)21(18)19/h2-11,13H,12H2,1H3,(H2,23,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201322 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)cc1 Show InChI InChI=1S/C21H18N4OS/c1-13-2-6-15(7-3-13)24-21(26)25-16-8-4-14(5-9-16)17-12-27-18-10-11-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201318 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 Show InChI InChI=1S/C20H15FN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201331 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-o...) Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1csc2ccnc(N)c12 Show InChI InChI=1S/C21H18N4OS/c1-13-4-2-3-5-17(13)25-21(26)24-15-8-6-14(7-9-15)16-12-27-18-10-11-23-20(22)19(16)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201305 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(c4)C#N)cc3)c12 Show InChI InChI=1S/C21H15N5OS/c22-11-13-2-1-3-16(10-13)26-21(27)25-15-6-4-14(5-7-15)17-12-28-18-8-9-24-20(23)19(17)18/h1-10,12H,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201324 (1-(3-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...) Show SMILES Cc1cccc(NC(=O)Nc2cccc(c2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C21H18N4OS/c1-13-4-2-6-15(10-13)24-21(26)25-16-7-3-5-14(11-16)17-12-27-18-8-9-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50201323 (1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2cccnc2)c1 Show InChI InChI=1S/C26H21N5OS/c1-16-4-2-6-20(12-16)31-26(32)30-19-9-7-17(8-10-19)22-15-33-24-21(14-29-25(27)23(22)24)18-5-3-11-28-13-18/h2-15H,1H3,(H2,27,29)(H2,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae (Firmicutes))	BDBM50137760 (2,4-dichloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[...) Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1sc2CCCc2c1C#N)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C19H17Cl2N3O4S2/c20-14-9-15(21)17(30(26,27)24-4-6-28-7-5-24)8-12(14)18(25)23-19-13(10-22)11-2-1-3-16(11)29-19/h8-9H,1-7H2,(H,23,25)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.				Chem Biol Drug Des 67: 58-65 (2006) Article DOI: 10.1111/j.1747-0285.2005.00317.x BindingDB Entry DOI: 10.7270/Q2GF0S0Z
					More data for this Ligand-Target Pair

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