BindingDB PrimarySearch

Found 46 hits with Last Name = 'bouchet' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate measured after 10 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate measured after 45 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate measured after 60 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate class 2a measured after 45 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate measured after 10 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate measured after 45 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate measured after 60 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 5 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 \| N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC4 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50499957 (CHEMBL3739529) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate measured after 15 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide \| CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM50525406 (CHEMBL164868) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC9 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50328678 (6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...) Show SMILES ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 \| N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC11 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50179360 (CHEMBL3040216) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant sirtuin 1 using fluorogenic HDAC substrate measured after 20 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 \| N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50179360 (CHEMBL3040216) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant sirtuin 2 using fluoro-lysine sirtuin 2 deacetylase substrate measured after 60 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide \| CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50499957 (CHEMBL3739529) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50499957 (CHEMBL3739529) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human))	BDBM27507 (3-Pyridinecarboxamide \| CHEMBL1140 \| NAM \| niacina...) Show SMILES NC(=O)c1cccnc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of human recombinant sirtuin 3 using fluoro-lysine sirtuin 2 deacetylase substrate measured after 45 mins by fluorimetry assay				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 \| N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide \| CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide \| CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50499957 (CHEMBL3739529) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) by fluorimetric assay				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of HDAC in human MeT-5A cells assessed as increase in transfected YFP fused histone H3 acetylation treated at 8 hrs after YFP fused H3 tra...				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50499957 (CHEMBL3739529) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50499958 (CHEMBL3740591) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50115661 (CHEMBL320497 \| N,8-dihydroxy-8-(hydroxyamino)octan...) Show SMILES ONC(=O)CCCCCCC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50005711 (CHEBI:46024 \| GNF-Pf-1011 \| TRICHOSTATIN \| Trichos...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA				Bioorg Med Chem Lett 26: 154-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.011 BindingDB Entry DOI: 10.7270/Q2BK1GCP
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase (Homo sapiens (Human))	BDBM50525404 (CHEMBL4563988) Show SMILES COC(=O)c1ccc2ccccc2c1OCCCCCCCC(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.84E+3	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of HDAC in human MeT-5A cells assessed as increase in transfected YFP fused histone H3 acetylation treated at 8 hrs after YFP fused H3 tra...				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50525405 (CHEMBL4516678) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.14E+3	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of HDAC in human MeT-5A cells assessed as increase in transfected YFP fused histone H3 acetylation treated at 8 hrs after YFP fused H3 tra...				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide \| CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.81E+3	n/a	n/a	n/a	n/a
UMR CNRS 7285 Curated by ChEMBL					Assay Description Inhibition of HDAC in human MeT-5A cells assessed as increase in transfected YFP fused histone H3 acetylation treated at 8 hrs after YFP fused H3 tra...				ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS
UMR CNRS 7285 Curated by ChEMBL					More data for this Ligand-Target Pair