Compile Data Set for Download or QSAR

Found 48 hits with Last Name = 'bruni' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205615 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2n[n+]([O-])c3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(16(17)14-9)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122013 (8-Chloro-5-oxy-benzo[e]pyrazolo[5,1-c][1,2,4]triaz...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)C(=O)OCc1cccs1 Show InChI InChI=1S/C15H9ClN4O3S/c16-9-3-4-12-13(6-9)19-14(18-20(12)22)11(7-17-19)15(21)23-8-10-2-1-5-24-10/h1-7H,8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205622 (8-ethoxy-3-iodo-benzo[e]pyrazolo[5,1-c][1,2,4]tria...) Show SMILES CCOc1ccc2[n+]([O-])nc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(14-16(9)17)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50078032 (8-Chloro-3-thiophen-3-yl-benzo[e]pyrazolo[5,1-c][1...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)-c1ccsc1 Show InChI InChI=1S/C13H7ClN4OS/c14-9-1-2-11-12(5-9)17-13(16-18(11)19)10(6-15-17)8-3-4-20-7-8/h1-7H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122842 (3-Pyridin-2-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccccn1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-11(10-4-6-21-9-10)7-17-14-12(8-18-19(14)15)13-3-1-2-5-16-13/h1-9,18H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122013 (8-Chloro-5-oxy-benzo[e]pyrazolo[5,1-c][1,2,4]triaz...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)C(=O)OCc1cccs1 Show InChI InChI=1S/C15H9ClN4O3S/c16-9-3-4-12-13(6-9)19-14(18-20(12)22)11(7-17-19)15(21)23-8-10-2-1-5-24-10/h1-7H,8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50205615 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2n[n+]([O-])c3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(16(17)14-9)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha3beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205616 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2nnc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O/c1-2-17-7-3-4-9-10(5-7)16-11(15-14-9)8(12)6-13-16/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	13.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha3beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122847 (3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccnc1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-13(11-3-5-21-9-11)7-17-14-12(8-18-19(14)15)10-2-1-4-16-6-10/h1-9,18H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	26.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	26.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50078032 (8-Chloro-3-thiophen-3-yl-benzo[e]pyrazolo[5,1-c][1...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)-c1ccsc1 Show InChI InChI=1S/C13H7ClN4OS/c14-9-1-2-11-12(5-9)17-13(16-18(11)19)10(6-15-17)8-3-4-20-7-8/h1-7H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50205622 (8-ethoxy-3-iodo-benzo[e]pyrazolo[5,1-c][1,2,4]tria...) Show SMILES CCOc1ccc2[n+]([O-])nc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(14-16(9)17)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha3beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122845 (3-(3-Methoxy-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1...) Show SMILES COc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H13N3O2S/c1-22-13-4-2-3-11(7-13)14-9-19-20-16(14)18-8-15(17(20)21)12-5-6-23-10-12/h2-10,19H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122848 (3-Naphthalen-1-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccc2ccccc12)-c1ccsc1 Show InChI InChI=1S/C20H13N3OS/c24-20-17(14-8-9-25-12-14)10-21-19-18(11-22-23(19)20)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,22H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50205616 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2nnc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O/c1-2-17-7-3-4-9-10(5-7)16-11(15-14-9)8(12)6-13-16/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha3beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122848 (3-Naphthalen-1-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccc2ccccc12)-c1ccsc1 Show InChI InChI=1S/C20H13N3OS/c24-20-17(14-8-9-25-12-14)10-21-19-18(11-22-23(19)20)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	196	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122847 (3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccnc1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-13(11-3-5-21-9-11)7-17-14-12(8-18-19(14)15)10-2-1-4-16-6-10/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	291	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122847 (3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccnc1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-13(11-3-5-21-9-11)7-17-14-12(8-18-19(14)15)10-2-1-4-16-6-10/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	315	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	383	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	383	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha3-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122845 (3-(3-Methoxy-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1...) Show SMILES COc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H13N3O2S/c1-22-13-4-2-3-11(7-13)14-9-19-20-16(14)18-8-15(17(20)21)12-5-6-23-10-12/h2-10,19H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	737	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM50122842 (3-Pyridin-2-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccccn1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-11(10-4-6-21-9-10)7-17-14-12(8-18-19(14)15)13-3-1-2-5-16-13/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122845 (3-(3-Methoxy-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1...) Show SMILES COc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H13N3O2S/c1-22-13-4-2-3-11(7-13)14-9-19-20-16(14)18-8-15(17(20)21)12-5-6-23-10-12/h2-10,19H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	827	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat alpha2-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122842 (3-Pyridin-2-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccccn1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-11(10-4-6-21-9-10)7-17-14-12(8-18-19(14)15)13-3-1-2-5-16-13/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	927	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2 (Rattus norvegicus (Rat)-RAT)	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha5-beta3-gamma2 subunits expresssed in HEK 293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122848 (3-Naphthalen-1-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccc2ccccc12)-c1ccsc1 Show InChI InChI=1S/C20H13N3OS/c24-20-17(14-8-9-25-12-14)10-21-19-18(11-22-23(19)20)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair