BindingDB PrimarySearch

Found 46 hits with Last Name = 'cieplak' and Initial = 'p'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidylate synthase (Mus musculus)	BDBM50423452 (CHEMBL401166) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50084626 (CHEMBL284440 \| N-(2-Benzo[1,3]dioxol-5-yl-ethyl)-N...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50110934 (CHEMBL30483 \| N-((1S,3S)-1-Benzyl-3-{[2-(2,4-dichl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423448 (CHEMBL254204) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423449 (CHEMBL253999) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50110932 (CHEMBL283863 \| N-(2-Benzo[1,3]dioxol-5-yl-ethyl)-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423450 (CHEMBL251934) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423455 (CHEMBL399050) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50110931 (CHEMBL284441 \| N-((1S,3S)-1-Benzyl-3-{[2-(2,4-dich...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423454 (CHEMBL400683) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423457 (CHEMBL251255) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423453 (CHEMBL401165) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50110933 (CHEMBL30571 \| N-(2-Benzo[1,3]dioxol-5-yl-ethyl)-3-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin D (Homo sapiens (Human))	BDBM50110935 ((E)-N-((1S,3S)-1-Benzyl-2-hydroxy-3-{(2-pyridin-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory activity of compound against human Cathepsin D				J Med Chem 45: 1412-9 (2002) BindingDB Entry DOI: 10.7270/Q25T3JSH
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423451 (CHEMBL254205) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.62E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423447 (CHEMBL255049) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Mus musculus)	BDBM50423456 (CHEMBL255050) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.02E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse thymidylate synthase in mouse L1210 cells				Bioorg Med Chem 15: 2346-58 (2007) Article DOI: 10.1016/j.bmc.2007.01.021 BindingDB Entry DOI: 10.7270/Q21G0NK7
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24572 ((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24573 ((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24574 ((2R)-1-[(2S,3R)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24575 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24569 ((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24570 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24576 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24571 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24577 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]-3-{[(4-m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24578 ((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24579 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24580 ((2S,5E)-6-(4-fluorophenyl)-1-[(2S,3S)-3-hexyl-4-ox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24581 ((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24582 ((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]propan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24583 ((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24569 ((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24585 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24586 ((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24587 ((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24588 ((1R)-1-{[(2S,3S)-3-butyl-4-oxooxetan-2-yl]methyl}d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24586 ((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24590 ((2S)-1-[(2S,3S)-3-octyl-4-oxooxetan-2-yl]undecan-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24591 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24592 ((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24593 ((2S)-1-[(2R,3R)-3-hexyl-4-oxooxetan-2-yl]pentadeca...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.74E+3	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24594 ((2S)-1-[(2S,3S)-3-methyl-4-oxooxetan-2-yl]tridecan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24595 ((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24596 ((2S)-1-[(2R,3R)-3-methyl-4-oxooxetan-2-yl]tridecan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.51E+4	n/a	n/a	n/a	n/a	7.4	37
The Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				J Med Chem 51: 5285-96 (2008) Article DOI: 10.1021/jm800321h BindingDB Entry DOI: 10.7270/Q2NV9GJH
The Burnham Institute for Medical Research					More data for this Ligand-Target Pair