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Compile Data Set for Download or QSAR

Found 66 hits with Last Name = 'civenni' and Initial = 'g'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562420
PNG
(CHEMBL4758825)
Show SMILES C(C[C@@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
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0.610n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562420
PNG
(CHEMBL4758825)
Show SMILES C(C[C@@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
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0.610n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569770
PNG
(CHEMBL4873323)
Show SMILES C(C[C@@H]1CCC[C@@H](O1)c1ccccc1)NCC1CCCCC1 |r|
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0.950n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562419
PNG
(CHEMBL4756284)
Show SMILES C(C[C@H]1CCC[C@H](C1)c1ccccc1)NCc1ccccc1 |r|
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1.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562418
PNG
(CHEMBL4793113)
Show SMILES C(C[C@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
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1.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569768
PNG
(CHEMBL4860790)
Show SMILES C(C[C@@H]1CCC[C@@H](O1)c1ccccc1)NCc1ccccc1 |r|
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1.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562417
PNG
(CHEMBL4746722)
Show SMILES C(C[C@@H]1CCC[C@H](C1)c1ccccc1)NCc1ccccc1 |r|
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1.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562417
PNG
(CHEMBL4746722)
Show SMILES C(C[C@@H]1CCC[C@H](C1)c1ccccc1)NCc1ccccc1 |r|
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1.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562425
PNG
(CHEMBL4741910)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@H](C1)c1ccccc1 |r|
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2n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569769
PNG
(CHEMBL4869117)
Show SMILES C(C[C@H]1CCC[C@H](O1)c1ccccc1)NCC1CCCCC1 |r|
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2.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562416
PNG
(CHEMBL4757626)
Show SMILES C(CCc1ccccc1)CNCCC1CCCC(C1)c1ccccc1
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3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562412
PNG
(CHEMBL4747167)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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3.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562415
PNG
(CHEMBL4751986)
Show SMILES CN(C)CCC1CCCC(C1)c1ccccc1
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4.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569767
PNG
(CHEMBL4858036)
Show SMILES C(C[C@H]1CCC[C@H](O1)c1ccccc1)NCc1ccccc1 |r|
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5.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50001028
PNG
((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...)
Show SMILES [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10|
Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1
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5.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50001028
PNG
((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...)
Show SMILES [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10|
Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1
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5.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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6.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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6.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562413
PNG
(CHEMBL4741498)
Show SMILES CN(C)CC[C@H]1CCC[C@H](C1)c1ccccc1 |r|
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562427
PNG
(CHEMBL4749981)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CCC[C@@H](C1)c1ccccc1 |r|
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13n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562414
PNG
(CHEMBL4754878)
Show SMILES CN(C)CC[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569772
PNG
(CHEMBL4875521)
Show SMILES C(CCc1ccccc1)CNCC[C@@H]1CCC[C@@H](O1)c1ccccc1 |r|
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15n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562426
PNG
(CHEMBL4797217)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569778
PNG
(CHEMBL4865171)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@@H]1CCC[C@@H](O1)c1ccccc1 |r|
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21n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569771
PNG
(CHEMBL4861025)
Show SMILES C(CCc1ccccc1)CNCC[C@H]1CCC[C@H](O1)c1ccccc1 |r|
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29n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569775
PNG
(CHEMBL4857336)
Show SMILES C(CN1CCCC1)[C@H]1CCC[C@H](O1)c1ccccc1 |r|
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31n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562425
PNG
(CHEMBL4741910)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@H](C1)c1ccccc1 |r|
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33n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50569769
PNG
(CHEMBL4869117)
Show SMILES C(C[C@H]1CCC[C@H](O1)c1ccccc1)NCC1CCCCC1 |r|
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36n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562421
PNG
(CHEMBL4754558)
Show SMILES NCC[C@@H]1CCC[C@H](C1)c1ccccc1 |r|
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43n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562418
PNG
(CHEMBL4793113)
Show SMILES C(C[C@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
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46n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562419
PNG
(CHEMBL4756284)
Show SMILES C(C[C@H]1CCC[C@H](C1)c1ccccc1)NCc1ccccc1 |r|
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47n/an/an/an/an/an/an/an/a


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Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50569770
PNG
(CHEMBL4873323)
Show SMILES C(C[C@@H]1CCC[C@@H](O1)c1ccccc1)NCC1CCCCC1 |r|
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57n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569777
PNG
(CHEMBL4859364)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@H]1CCC[C@H](O1)c1ccccc1 |r|
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57n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50009307
PNG
(DITOLYLGUANIDINE | Di-o-tolylguanidine)
Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
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58n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50009307
PNG
(DITOLYLGUANIDINE | Di-o-tolylguanidine)
Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
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58n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50569776
PNG
(CHEMBL4861960)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@@H](O1)c1ccccc1 |r|
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60n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562412
PNG
(CHEMBL4747167)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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61n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562414
PNG
(CHEMBL4754878)
Show SMILES CN(C)CC[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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76n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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78n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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78n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50009307
PNG
(DITOLYLGUANIDINE | Di-o-tolylguanidine)
Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
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89n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50009307
PNG
(DITOLYLGUANIDINE | Di-o-tolylguanidine)
Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
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89n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562416
PNG
(CHEMBL4757626)
Show SMILES C(CCc1ccccc1)CNCCC1CCCC(C1)c1ccccc1
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93n/an/an/an/an/an/an/an/a


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Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50569776
PNG
(CHEMBL4861960)
Show SMILES C(CN1CCCC1)[C@@H]1CCC[C@@H](O1)c1ccccc1 |r|
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115n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562415
PNG
(CHEMBL4751986)
Show SMILES CN(C)CCC1CCCC(C1)c1ccccc1
UniProtKB/SwissProt

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115n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562426
PNG
(CHEMBL4797217)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@@H]1CCC[C@@H](C1)c1ccccc1 |r|
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118n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562420
PNG
(CHEMBL4758825)
Show SMILES C(C[C@@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
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130n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50562420
PNG
(CHEMBL4758825)
Show SMILES C(C[C@@H]1CCC[C@@H](C1)c1ccccc1)NCc1ccccc1 |r|
UniProtKB/SwissProt

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130n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Rattus norvegicus (Rat))
BDBM50569778
PNG
(CHEMBL4865171)
Show SMILES C(CN1CCN(CC1)c1ccccc1)[C@@H]1CCC[C@@H](O1)c1ccccc1 |r|
UniProtKB/SwissProt

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131n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113443
BindingDB Entry DOI: 10.7270/Q2JM2FD9
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50562423
PNG
(CHEMBL4758163)
Show SMILES NCC[C@H]1CCC[C@H](C1)c1ccccc1 |r|
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138n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112950
BindingDB Entry DOI: 10.7270/Q25M69F6
More data for this
Ligand-Target Pair
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