| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50569772 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2110101 (CHEMBL4818776) |
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| Ki | 15±n/a nM |
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| Citation |  Kopp, N; Civenni, G; Marson, D; Laurini, E; Pricl, S; Catapano, CV; Humpf, HU; Almansa, C; Nieto, FR; Schepmann, D; Wünsch, B Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high ? Eur J Med Chem219:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50569772 |
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| n/a |
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| Name | BDBM50569772 |
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| Synonyms: | CHEMBL4875521 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31NO |
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| Mol. Mass. | 337.4983 |
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| SMILES | C(CCc1ccccc1)CNCC[C@@H]1CCC[C@@H](O1)c1ccccc1 |r| |
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| Structure | 
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