Found 322 hits with Last Name = 'clausen' and Initial = 'dj' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514590
(US11098029, Example 26)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:15.16,8.8,5.5,wD:21.25,18.18,(3.21,-6.71,;4.12,-5.46,;3.49,-4.05,;1.96,-3.89,;4.4,-2.81,;5.94,-2.81,;6.84,-4.05,;6.41,-1.34,;5.17,-.44,;5.17,1.1,;6.5,1.87,;7.27,.54,;5.73,3.21,;7.83,2.64,;7.83,4.18,;3.92,-1.34,;2.45,-.87,;1.31,-1.9,;-.15,-1.42,;-.47,.08,;-1.94,.56,;-3.08,-.47,;-2.76,-1.98,;-1.3,-2.45,;-4.55,.01,;-4.87,1.51,;-6.33,1.99,;-7.48,.96,;-7.16,-.55,;-8.3,-1.58,;-5.69,-1.03,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514601
(US11098029, Example 37)Show SMILES COc1ccc(CN([C@H]2C[C@@H](C)N([C@H]2CO[C@H]2CC[C@H](CC2)c2cccc(F)c2)C(=O)OCc2ccccc2)S(=O)(=O)N(C)C)cc1 |r,wU:10.10,8.7,13.14,16.16,19.23,(-8.92,-1.04,;-7.39,-1.2,;-6.49,.05,;-7.11,1.45,;-6.21,2.7,;-4.67,2.54,;-3.77,3.78,;-2.24,3.62,;-1.33,4.87,;-1.81,6.33,;-.56,7.24,;-.56,8.78,;.68,6.33,;.21,4.87,;1.11,3.62,;2.64,3.78,;3.55,2.54,;5.08,2.7,;5.99,1.45,;5.36,.05,;3.83,-.12,;2.92,1.13,;6.26,-1.2,;5.64,-2.61,;6.54,-3.85,;8.08,-3.69,;8.7,-2.29,;10.23,-2.12,;7.8,-1.04,;2.15,6.81,;3.29,5.78,;2.47,8.31,;1.32,9.35,;1.64,10.85,;.5,11.88,;.82,13.39,;2.28,13.86,;3.43,12.83,;3.11,11.33,;-1.61,2.22,;-.2,2.84,;-3.02,1.59,;-.99,.81,;.55,.65,;-1.89,-.44,;-4.05,1.13,;-4.95,-.12,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514589
(US11098029, Example 25)Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1)C(=O)OC |r,wU:17.21,14.14,11.12,6.5,8.8,(-.26,2.51,;.65,1.26,;2.18,1.42,;2.02,2.96,;2.34,-.11,;3.71,1.59,;4.62,.34,;6.16,.34,;6.63,-1.13,;7.96,-1.9,;5.39,-2.03,;4.14,-1.13,;2.65,-1.52,;1.56,-.43,;.08,-.83,;-.32,-2.32,;-1.81,-2.72,;-2.9,-1.63,;-2.5,-.14,;-1.01,.26,;-4.39,-2.03,;-4.79,-3.52,;-6.27,-3.92,;-7.36,-2.83,;-6.96,-1.34,;-8.05,-.25,;-5.48,-.94,;5.39,-3.57,;4.05,-4.34,;6.72,-4.34,;8.05,-3.57,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606050
(US11680060, Example 124)Show SMILES CC(C)OC(=O)N1CCC[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606079
(US11680060, Example 166)Show SMILES CCOC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514632
(US11098029, Example 67)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:8.8,5.5,16.17,19.19,22.26,(8.37,-3.54,;7.03,-4.31,;5.7,-3.54,;4.36,-4.31,;5.7,-2,;6.94,-1.1,;8.41,-1.57,;6.47,.37,;4.93,.37,;4.02,1.61,;4.65,3.02,;3.24,3.65,;5.28,4.43,;6.06,2.39,;7.2,3.42,;6.83,1.06,;4.45,-1.1,;2.99,-1.57,;1.84,-.54,;.38,-1.02,;.06,-2.52,;-1.41,-3,;-2.55,-1.97,;-2.23,-.46,;-.77,.01,;-4.02,-2.45,;-4.34,-3.95,;-5.8,-4.43,;-6.94,-3.4,;-6.62,-1.89,;-7.77,-.86,;-5.16,-1.41,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514585
(US11098029, Example 21)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cc(F)ccc1F |r,wU:22.26,19.19,16.17,8.8,5.5,(4.45,-5.1,;5.22,-3.77,;4.45,-2.43,;2.91,-2.43,;5.22,-1.1,;6.76,-1.1,;7.53,-2.43,;7.24,.36,;5.99,1.27,;5.99,2.81,;4.66,3.56,;4.64,5.1,;5.99,4.33,;3.34,2.78,;2,3.55,;2.57,1.44,;4.75,.36,;3.41,1.13,;2.08,.36,;.59,.76,;-.5,-.33,;-1.98,.07,;-2.38,1.56,;-1.29,2.65,;.2,2.25,;-3.87,1.96,;-4.96,.87,;-6.45,1.27,;-7.53,.18,;-6.84,2.76,;-5.76,3.85,;-4.27,3.45,;-3.18,4.54,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514582
(US11098029, Example 18)Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)OC |r,wU:11.12,14.14,6.5,8.8,17.21,(7.6,1.68,;8.51,.43,;7.88,-.97,;6.48,-.35,;9.29,-1.6,;7.26,-2.38,;8.16,-3.63,;9.7,-3.63,;10.18,-5.09,;11.51,-5.86,;8.93,-6,;7.69,-5.09,;6.2,-5.49,;5.11,-4.4,;3.62,-4.8,;3.22,-6.29,;1.74,-6.69,;.59,-5.61,;1.05,-4.11,;2.53,-3.71,;-.89,-6.01,;-1.29,-7.5,;-2.78,-7.9,;-3.87,-6.81,;-3.47,-5.32,;-1.98,-4.92,;8.93,-7.54,;10.27,-8.31,;7.6,-8.31,;6.42,-7.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514580
(US11098029, Example 16)Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)OCC(F)F |r,wU:8.8,11.12,14.14,6.5,17.21,(9.86,-.89,;9.09,-2.23,;7.55,-2.23,;6.78,-.89,;8.32,-3.56,;6.78,-3.56,;7.55,-4.89,;9.09,-4.89,;9.57,-6.36,;11.06,-6.76,;8.32,-7.26,;7.08,-6.36,;5.59,-6.76,;4.5,-5.67,;3.01,-6.07,;2.62,-7.55,;1.13,-7.95,;.04,-6.86,;.44,-5.38,;1.93,-4.98,;-1.45,-7.26,;-2.59,-6.23,;-4.06,-6.71,;-4.38,-8.21,;-3.23,-9.24,;-1.77,-8.77,;8.32,-8.8,;6.99,-9.57,;9.66,-9.57,;9.66,-11.11,;8.32,-11.88,;6.99,-11.11,;8.32,-13.42,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514583
(US11098029, Example 19)Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)OC |r,wU:11.12,14.14,6.5,8.8,17.21,(7.6,1.66,;8.51,.41,;7.88,-.99,;6.48,-.37,;9.29,-1.62,;7.26,-2.4,;8.16,-3.65,;9.7,-3.65,;10.18,-5.11,;11.51,-5.88,;8.93,-6.01,;7.69,-5.11,;6.2,-5.51,;5.11,-4.42,;3.62,-4.82,;3.22,-6.31,;1.74,-6.7,;.59,-5.63,;1.05,-4.13,;2.53,-3.73,;-.89,-6.03,;-1.29,-7.52,;-2.78,-7.91,;-3.87,-6.82,;-3.47,-5.34,;-1.98,-4.94,;8.93,-7.55,;10.27,-8.32,;7.6,-8.32,;6.42,-7.34,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514596
(US11098029, Example 32)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cc(F)cc(F)c1 |r,wU:16.17,5.5,8.8,wD:22.26,19.19,(2.74,-7,;3.65,-5.76,;3.02,-4.35,;1.49,-4.19,;3.92,-3.1,;5.46,-3.1,;6.37,-4.35,;5.94,-1.64,;4.69,-.73,;4.69,.81,;6.03,1.58,;6.8,.24,;5.26,2.91,;7.36,2.35,;7.36,3.89,;8.7,1.58,;3.45,-1.64,;1.98,-1.16,;.84,-2.19,;-.63,-1.72,;-.95,-.21,;-2.41,.26,;-3.55,-.77,;-3.23,-2.27,;-1.77,-2.75,;-5.02,-.29,;-5.34,1.22,;-6.8,1.69,;-7.12,3.2,;-7.95,.66,;-7.63,-.85,;-8.77,-1.88,;-6.16,-1.32,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514581
(US11098029, Example 17)Show SMILES CNS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1)C(=O)OCC(F)F |r,wU:11.12,14.14,6.5,8.8,17.21,(7.6,-1.02,;8.51,-2.27,;7.88,-3.67,;9.29,-4.3,;6.48,-3.05,;7.26,-5.08,;8.16,-6.33,;9.7,-6.33,;10.18,-7.79,;11.51,-8.56,;8.93,-8.69,;7.69,-7.79,;6.2,-8.19,;5.11,-7.1,;3.62,-7.5,;3.22,-8.99,;1.74,-9.38,;.59,-8.31,;1.05,-6.81,;2.53,-6.41,;-.89,-8.71,;-1.29,-10.2,;-2.78,-10.59,;-3.87,-9.5,;-3.47,-8.02,;-1.98,-7.62,;8.93,-10.23,;7.6,-11,;10.27,-11,;10.27,-12.54,;8.93,-13.31,;7.6,-12.54,;8.93,-14.85,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605963
(US11680060, Example 30)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514618
(US11098029, Example 53)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)CC#N)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:8.8,18.19,21.21,5.5,24.28,(-.46,-22.67,;1.01,-23.15,;2.15,-22.12,;1.83,-20.61,;3.61,-22.59,;4.09,-24.06,;3.19,-25.3,;5.63,-24.06,;6.11,-22.59,;7.57,-22.12,;7.89,-20.61,;9.4,-20.93,;6.39,-20.29,;8.21,-19.11,;7.07,-18.08,;9.68,-18.63,;10.82,-19.66,;11.97,-20.69,;4.86,-21.69,;4.86,-20.15,;3.53,-19.38,;3.53,-17.84,;2.19,-17.07,;2.19,-15.53,;3.53,-14.76,;4.86,-15.53,;4.86,-17.07,;3.53,-13.22,;4.86,-12.45,;4.86,-10.91,;3.53,-10.14,;2.19,-10.91,;.86,-10.14,;2.19,-12.45,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606039
(US11680060, Example 113)Show SMILES COC(=O)N1[C@@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)[C@H](C[C@H]1C(F)F)NS(=O)(=O)CF |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605999
(US11680060, Example 66)Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)N1C(=O)OCC(F)F |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514586
(US11098029, Example 22)Show SMILES C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@H](CO[C@H]2CC[C@H](CC2)c2cc(F)ccc2F)N1C(=O)OCC(F)F |r,wU:17.20,14.13,11.11,3.3,1.0,(7.53,-1.1,;6.76,.23,;7.24,1.7,;5.99,2.6,;5.99,4.14,;4.66,4.89,;4.64,6.43,;5.99,5.66,;3.34,4.11,;2,4.88,;2.57,2.78,;4.75,1.7,;3.41,2.47,;2.08,1.7,;.59,2.1,;-.5,1.01,;-1.98,1.41,;-2.38,2.89,;-1.29,3.98,;.2,3.58,;-3.87,3.29,;-4.96,2.2,;-6.45,2.6,;-7.53,1.51,;-6.84,4.09,;-5.76,5.18,;-4.27,4.78,;-3.18,5.87,;5.22,.23,;4.45,-1.1,;2.91,-1.1,;5.22,-2.43,;4.45,-3.77,;5.22,-5.1,;6.76,-5.1,;4.45,-6.43,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514619
(US11098029, Example 54)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)CCC#N)[C@@H]1CO[C@H]1CCC(CC1)c1cccc(F)c1 |r,wU:22.22,19.20,5.5,8.8,(4,-3.81,;3.61,-2.32,;4.69,-1.23,;6.18,-1.63,;4.3,.26,;5.2,1.5,;6.74,1.5,;4.3,2.75,;2.83,2.27,;1.5,3.04,;1.5,4.58,;-.04,4.58,;.73,5.91,;2.83,5.35,;2.83,6.89,;4.16,4.58,;5.5,5.35,;6.83,4.58,;8.17,3.81,;2.83,.73,;1.74,-.36,;.25,.04,;-.83,-1.05,;-.44,-2.54,;-1.53,-3.62,;-3.01,-3.23,;-3.41,-1.74,;-2.32,-.65,;-4.1,-4.31,;-3.7,-5.8,;-4.79,-6.89,;-6.28,-6.49,;-6.68,-5.01,;-8.17,-4.61,;-5.59,-3.92,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514616
(US11098029, Example 51)Show SMILES COC[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@H](CO[C@H]2CC[C@H](CC2)c2cccc(F)c2)N1C(=O)OC |r,wU:3.2,13.13,16.15,19.22,5.5,(-2.2,-1.03,;-2.2,-2.57,;-.87,-3.34,;-.87,-4.88,;-2.11,-5.79,;-1.64,-7.25,;-2.54,-8.5,;-4.08,-8.34,;-3.91,-6.81,;-4.24,-9.87,;-5.61,-8.18,;-6.51,-9.42,;-6.23,-6.77,;-.1,-7.25,;.81,-8.5,;2.34,-8.34,;3.24,-9.59,;4.77,-9.42,;5.68,-10.67,;5.05,-12.08,;3.52,-12.24,;2.62,-10.99,;5.96,-13.32,;5.33,-14.73,;6.24,-15.98,;7.77,-15.81,;8.4,-14.41,;9.93,-14.25,;7.49,-13.16,;.38,-5.79,;1.84,-5.31,;2.16,-3.81,;2.99,-6.34,;4.45,-5.87,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605992
(US11680060, Example 59)Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)N1C(=O)OCC1CC1(F)F |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514636
(US11098029, Example 71)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cc(F)cc(F)c1 |r,wU:8.8,5.5,16.17,19.19,22.26,(8.05,-3.54,;6.71,-4.31,;5.38,-3.54,;4.04,-4.31,;5.38,-2,;6.62,-1.1,;8.09,-1.57,;6.15,.37,;4.61,.37,;3.7,1.61,;4.33,3.02,;2.92,3.65,;4.96,4.43,;5.74,2.39,;6.88,3.42,;6.51,1.06,;4.13,-1.1,;2.67,-1.57,;1.52,-.54,;.06,-1.02,;-.26,-2.52,;-1.73,-3,;-2.87,-1.97,;-2.55,-.46,;-1.09,.01,;-4.34,-2.45,;-5.48,-1.41,;-6.94,-1.89,;-8.09,-.86,;-7.26,-3.4,;-6.12,-4.43,;-6.44,-5.93,;-4.66,-3.95,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514599
(US11098029, Example 35 | US11098029, Example 36)Show SMILES COC(=O)N1[C@H](C)C[C@@H]([C@@H]1CO[C@H]1CCC(CC1)OCc1ccccc1)N(Cc1ccc(OC)cc1)S(=O)(=O)N(C)C |r,wD:12.12,9.10,8.28,5.5,(5.88,-17.41,;4.41,-17.89,;4.09,-19.4,;5.24,-20.43,;2.63,-19.87,;2.15,-21.34,;3.06,-22.58,;.61,-21.34,;.13,-19.87,;1.38,-18.97,;1.38,-17.43,;2.71,-16.66,;2.71,-15.12,;4.05,-14.35,;4.05,-12.81,;2.71,-12.04,;1.38,-12.81,;1.38,-14.35,;2.71,-10.5,;1.38,-9.73,;.05,-10.5,;-1.29,-9.73,;-2.62,-10.5,;-2.62,-12.04,;-1.29,-12.81,;.05,-12.04,;-1.33,-19.4,;-2.47,-20.43,;-2.15,-21.93,;-3.3,-22.96,;-2.98,-24.47,;-1.51,-24.95,;-1.19,-26.45,;.27,-26.93,;-.37,-23.92,;-.69,-22.41,;-1.65,-17.89,;-3.16,-18.21,;-.14,-17.57,;-1.97,-16.38,;-3.44,-15.91,;-.83,-15.35,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605996
(US11680060, Example 63)Show SMILES CC(OC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1)C(F)F |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606038
(US11680060, Example 112)Show SMILES COC(=O)N1[C@@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)[C@H](C[C@H]1C(F)F)NS(=O)(=O)C(F)F |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606076
(US11680060, Example 161)Show SMILES CC(C)OC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514621
(US11098029, Example 56)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)CCO)[C@@H]1CO[C@H]1CCC(CC1)c1cccc(F)c1 |r,wU:21.21,18.19,5.5,8.8,(4.67,-3.81,;4.27,-2.32,;5.36,-1.23,;6.85,-1.63,;4.96,.26,;5.87,1.5,;7.41,1.5,;4.96,2.75,;3.5,2.27,;2.16,3.04,;2.16,4.58,;.62,4.58,;1.39,5.91,;3.5,5.35,;3.5,6.89,;4.83,4.58,;6.16,5.35,;7.5,4.58,;3.5,.73,;2.41,-.36,;.92,.04,;-.17,-1.05,;.23,-2.54,;-.86,-3.62,;-2.35,-3.23,;-2.74,-1.74,;-1.66,-.65,;-3.43,-4.31,;-3.04,-5.8,;-4.12,-6.89,;-5.61,-6.49,;-6.01,-5.01,;-7.5,-4.61,;-4.92,-3.92,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606012
(US11680060, Example 79 | US11680060, Example 94)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1COC1CCC2(CC2C1)c1ncc(Cl)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606047
(US11680060, Example 121)Show SMILES CC(C)OC(=O)N1CCC[C@H](NS(=O)(=O)C(F)F)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606055
(US11680060, Example 129)Show SMILES CCS(=O)(=O)N[C@@H]1[C@H](COC2CCC3(CC3C2)c2ncc(F)cn2)N([C@@H]2CCC[C@H]12)C(=O)OC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605971
(US11680060, Example 38)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)C(C)C)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514587
(US11098029, Example 23)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1F |r,wU:22.26,19.19,16.17,8.8,5.5,(4.11,-5.1,;4.88,-3.77,;4.11,-2.43,;2.57,-2.43,;4.88,-1.1,;6.42,-1.1,;7.19,-2.43,;6.9,.36,;5.65,1.27,;5.65,2.81,;4.32,3.56,;4.3,5.1,;5.65,4.33,;2.99,2.78,;1.66,3.55,;2.22,1.44,;4.4,.36,;3.07,1.13,;1.74,.36,;.25,.76,;-.84,-.33,;-2.33,.07,;-2.73,1.56,;-1.64,2.65,;-.15,2.25,;-4.21,1.96,;-5.3,.87,;-6.79,1.27,;-7.19,2.76,;-6.1,3.85,;-4.61,3.45,;-3.52,4.54,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514590
(US11098029, Example 26)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:15.16,8.8,5.5,wD:21.25,18.18,(3.21,-6.71,;4.12,-5.46,;3.49,-4.05,;1.96,-3.89,;4.4,-2.81,;5.94,-2.81,;6.84,-4.05,;6.41,-1.34,;5.17,-.44,;5.17,1.1,;6.5,1.87,;7.27,.54,;5.73,3.21,;7.83,2.64,;7.83,4.18,;3.92,-1.34,;2.45,-.87,;1.31,-1.9,;-.15,-1.42,;-.47,.08,;-1.94,.56,;-3.08,-.47,;-2.76,-1.98,;-1.3,-2.45,;-4.55,.01,;-4.87,1.51,;-6.33,1.99,;-7.48,.96,;-7.16,-.55,;-8.3,-1.58,;-5.69,-1.03,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605969
(US11680060, Example 36)Show SMILES CCS(=O)(=O)N[C@H]1C[C@@H](C)N([C@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1)C(=O)OC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514593
(US11098029, Example 29)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1 |r,wU:21.25,18.18,15.16,5.5,8.8,(4.11,-5.11,;4.88,-3.78,;4.11,-2.44,;2.57,-2.44,;4.88,-1.11,;6.42,-1.11,;7.19,-2.44,;6.9,.36,;5.65,1.26,;5.65,2.8,;4.32,3.57,;4.32,5.11,;5.65,4.34,;2.98,2.8,;1.65,3.57,;4.4,.36,;3.07,1.13,;1.74,.36,;.25,.75,;-.84,-.34,;-2.33,.06,;-2.73,1.55,;-1.64,2.64,;-.15,2.24,;-4.21,1.95,;-5.3,.86,;-6.79,1.26,;-7.19,2.75,;-6.1,3.84,;-4.61,3.44,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605945
(US11680060, Example 186 | US11680060, Example 187 ...)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1COC1CCC2(CC2C1)c1ncccn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606051
(US11680060, Example 125)Show SMILES CC(C)OC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606044
(US11680060, Example 118)Show SMILES CCS(=O)(=O)N[C@H]1C[C@@H](C(F)F)N([C@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1)C(=O)OC(C)C |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606020
(US11680060, Example 89)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1COC1CCC2(CC2C1)c1ncc(Br)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514624
(US11098029, Example 59)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)CCOC(F)(F)F)[C@@H]1CO[C@H]1CCC(CC1)c1cccc(F)c1 |r,wU:25.25,22.23,5.5,8.8,(3.34,-3.81,;2.94,-2.32,;4.03,-1.23,;5.51,-1.63,;3.63,.26,;4.53,1.5,;6.07,1.5,;3.63,2.75,;2.16,2.27,;.83,3.04,;.83,4.58,;-.71,4.58,;.06,5.91,;2.16,5.35,;2.16,6.89,;3.5,4.58,;4.83,5.35,;6.16,4.58,;7.5,5.35,;8.83,4.58,;7.5,6.89,;8.83,6.12,;2.16,.73,;1.07,-.36,;-.41,.04,;-1.5,-1.05,;-1.1,-2.54,;-2.19,-3.62,;-3.68,-3.23,;-4.08,-1.74,;-2.99,-.65,;-4.77,-4.31,;-4.37,-5.8,;-5.46,-6.89,;-6.95,-6.49,;-7.34,-5.01,;-8.83,-4.61,;-6.26,-3.92,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514588
(US11098029, Example 24)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)c1cccc(F)c1 |r,wU:20.24,17.17,14.15,8.8,5.5,(8.05,-3.57,;6.72,-4.34,;5.39,-3.57,;4.05,-4.34,;5.39,-2.03,;6.63,-1.13,;7.96,-1.9,;6.16,.34,;4.62,.34,;3.71,1.59,;2.18,1.42,;.65,1.26,;2.02,2.96,;2.34,-.11,;4.14,-1.13,;2.65,-1.52,;1.56,-.43,;.08,-.83,;-.32,-2.32,;-1.81,-2.72,;-2.9,-1.63,;-2.5,-.14,;-1.01,.26,;-4.39,-2.03,;-4.79,-3.52,;-6.27,-3.92,;-7.36,-2.83,;-6.96,-1.34,;-8.05,-.25,;-5.48,-.94,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606037
(US11680060, Example 111)Show SMILES CC(C)OC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1COC1CCC2(CC2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605988
(US11680060, Example 55)Show SMILES C[C@H]1[C@H](COC(=O)N2[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]2CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)C1(F)F |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606029
(US11680060, Example 100)Show SMILES CC(C)OC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)CF)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514592
(US11098029, Example 28)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)c1c(F)ccc(F)c1F |r,wU:20.24,17.17,14.15,5.5,8.8,(4.11,-5.22,;4.88,-3.88,;4.11,-2.55,;2.57,-2.55,;4.88,-1.22,;6.42,-1.22,;7.19,-2.55,;6.9,.25,;5.65,1.15,;5.65,2.69,;4.32,3.46,;2.98,2.69,;4.32,5,;5.65,4.23,;4.4,.25,;3.07,1.02,;1.74,.25,;.25,.65,;-.84,-.44,;-2.33,-.04,;-2.73,1.44,;-1.64,2.53,;-.15,2.13,;-4.21,1.84,;-5.3,.75,;-4.9,-.73,;-6.79,1.15,;-7.19,2.64,;-6.1,3.73,;-6.5,5.22,;-4.61,3.33,;-3.52,4.42,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514628
(US11098029, Example 63)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ccc(C#N)c(C)c1 |r,wU:16.17,19.19,22.26,5.5,8.8,(10.61,-16.15,;9.27,-16.92,;7.94,-16.15,;6.61,-16.92,;7.94,-14.61,;9.19,-13.71,;10.67,-14.1,;8.71,-12.24,;7.17,-12.24,;6.4,-10.91,;7.17,-9.57,;8.66,-9.17,;6.08,-8.48,;7.94,-8.24,;9.48,-8.24,;7.17,-6.91,;6.69,-13.71,;5.21,-14.1,;4.12,-13.01,;2.63,-13.41,;2.23,-14.9,;.74,-15.3,;-.34,-14.21,;.05,-12.72,;1.54,-12.32,;-1.83,-14.61,;-2.92,-13.52,;-4.41,-13.92,;-4.86,-15.41,;-6.36,-15.76,;-7.86,-16.12,;-3.78,-16.55,;-4.19,-18.04,;-2.23,-16.1,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM605982
(US11680060, Example 49)Show SMILES C[C@@H]1C[C@H](NS(C)(=O)=O)[C@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(F)cn2)N1C(=O)OCC1CC(F)C1 |r,wU:17.16,12.11,9.9,1.0,3.3,wD:15.20,(19.51,-11.94,;17.98,-11.78,;17.21,-10.44,;15.7,-10.76,;14.56,-9.73,;14.56,-8.19,;14.56,-6.65,;16.1,-8.19,;13.02,-8.19,;15.54,-12.29,;14.21,-13.06,;12.87,-12.29,;11.54,-13.06,;11.54,-14.6,;10.21,-15.37,;8.87,-14.6,;7.54,-13.83,;8.87,-13.06,;10.21,-12.29,;7.54,-15.37,;6.2,-14.6,;4.87,-15.37,;4.87,-16.91,;3.54,-17.68,;6.2,-17.68,;7.54,-16.91,;16.95,-12.92,;17.27,-14.43,;18.73,-14.9,;16.12,-15.46,;16.12,-17,;14.79,-17.77,;13.3,-17.37,;12.9,-18.86,;11.57,-19.63,;14.39,-19.25,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606041
(US11680060, Example 115)Show SMILES COC(=O)N1[C@@H](CO[C@H]2CC[C@]3(C[C@H]3C2)c2ncc(Cl)cn2)[C@H](C[C@H]1C(F)F)NS(=O)(=O)CF |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM514604
(US11098029, Example 39)Show SMILES CC(C)OC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)N(C)C)[C@@H]1COC1CCN(CC1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C250MP |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606021
(US11680060, Example 90)Show SMILES CC(C)OC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)C(F)F)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(F)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM606011
(US11680060, Example 78)Show SMILES COC(=O)N1[C@H](C)C[C@H](NS(=O)(=O)C(F)F)[C@@H]1CO[C@H]1CC[C@]2(C[C@H]2C1)c1ncc(Cl)cn1 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25Q516D |
More data for this
Ligand-Target Pair | |
Search and Browse
