Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM21492 (4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Inc Curated by ChEMBL | Assay Description Inhibition of Transforming growth factor beta-1 receptor (TbetaRI) autophosphorylation | Bioorg Med Chem Lett 13: 4355-9 (2003) BindingDB Entry DOI: 10.7270/Q29886FH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Inc Curated by ChEMBL | Assay Description Inhibition of Transforming growth factor beta-1 receptor (TbetaRI) | Bioorg Med Chem Lett 13: 4355-9 (2003) BindingDB Entry DOI: 10.7270/Q29886FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM21492 (4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Biogen Inc Curated by ChEMBL | Assay Description Dissociation constant for TGF-beta receptor type I | Bioorg Med Chem Lett 13: 4355-9 (2003) BindingDB Entry DOI: 10.7270/Q29886FH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |