Compile Data Set for Download or QSAR

Found 10 hits with Last Name = 'corcoran' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heparanase (Homo sapiens (Human))	BDBM50175932 (1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1 Show InChI InChI=1S/C31H28N6O/c1-17-13-25-26(14-18(17)2)35-29(34-25)21-5-9-23(10-6-21)32-31(38)33-24-11-7-22(8-12-24)30-36-27-15-19(3)20(4)16-28(27)37-30/h5-16H,1-4H3,(H,34,35)(H,36,37)(H2,32,33,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175936 (1,3-bis(4-(6-methyl-1H-benzo[d]imidazol-2-yl)pheny...) Show SMILES Cc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccc(C)cc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O/c1-17-3-13-23-25(15-17)34-27(32-23)19-5-9-21(10-6-19)30-29(36)31-22-11-7-20(8-12-22)28-33-24-14-4-18(2)16-26(24)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175931 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...) Show SMILES Cc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C28H22N6O/c1-17-5-4-8-24-25(17)34-27(33-24)19-11-15-21(16-12-19)30-28(35)29-20-13-9-18(10-14-20)26-31-22-6-2-3-7-23(22)32-26/h2-16H,1H3,(H,31,32)(H,33,34)(H2,29,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175938 (1,3-bis(4-(7-methyl-1H-benzo[d]imidazol-2-yl)pheny...) Show SMILES Cc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3c(C)cccc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O/c1-17-5-3-7-23-25(17)34-27(32-23)19-9-13-21(14-10-19)30-29(36)31-22-15-11-20(12-16-22)28-33-24-8-4-6-18(2)26(24)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175939 (1,3-bis-[4-(1H-benzoimidazol-2-yl)phenyl]urea | CH...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2[nH]1)Nc1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C27H20N6O/c34-27(28-19-13-9-17(10-14-19)25-30-21-5-1-2-6-22(21)31-25)29-20-15-11-18(12-16-20)26-32-23-7-3-4-8-24(23)33-26/h1-16H,(H,30,31)(H,32,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175937 (1,3-bis(4-(7-methoxy-1H-benzo[d]imidazol-2-yl)phen...) Show SMILES COc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3c(OC)cccc3[nH]2)cc1 Show InChI InChI=1S/C29H24N6O3/c1-37-23-7-3-5-21-25(23)34-27(32-21)17-9-13-19(14-10-17)30-29(36)31-20-15-11-18(12-16-20)28-33-22-6-4-8-24(38-2)26(22)35-28/h3-16H,1-2H3,(H,32,34)(H,33,35)(H2,30,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175933 (1,3-bis(4-(1H-imidazo[4,5-c]pyridin-2-yl)phenyl)ur...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccncc2[nH]1)Nc1ccc(cc1)-c1nc2ccncc2[nH]1 Show InChI InChI=1S/C25H18N8O/c34-25(28-17-5-1-15(2-6-17)23-30-19-9-11-26-13-21(19)32-23)29-18-7-3-16(4-8-18)24-31-20-10-12-27-14-22(20)33-24/h1-14H,(H,30,32)(H,31,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175934 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(1H-im...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2[nH]1)Nc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C26H19N7O/c34-26(28-18-11-7-16(8-12-18)23-30-20-4-1-2-5-21(20)31-23)29-19-13-9-17(10-14-19)24-32-22-6-3-15-27-25(22)33-24/h1-15H,(H,30,31)(H,27,32,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175930 (1-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-(4-(7-met...) Show SMILES COc1cccc2[nH]c(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)-c2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C28H22N6O2/c1-36-24-8-4-7-23-25(24)34-27(33-23)18-11-15-20(16-12-18)30-28(35)29-19-13-9-17(10-14-19)26-31-21-5-2-3-6-22(21)32-26/h2-16H,1H3,(H,31,32)(H,33,34)(H2,29,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50175935 (1,3-bis(4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl)ur...) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ncccc2[nH]1)Nc1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C25H18N8O/c34-25(28-17-9-5-15(6-10-17)21-30-19-3-1-13-26-23(19)32-21)29-18-11-7-16(8-12-18)22-31-20-4-2-14-27-24(20)33-22/h1-14H,(H,26,30,32)(H,27,31,33)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibitory activity against heparanase from human platelets				Bioorg Med Chem Lett 16: 409-12 (2005) Article DOI: 10.1016/j.bmcl.2005.09.069 BindingDB Entry DOI: 10.7270/Q2ST7PDB
					More data for this Ligand-Target Pair