Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286954 (CHEMBL176689 | N-{4-[3-(3,4-Dihydroxy-phenyl)-prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286969 (CHEMBL367410 | N-{4-[2-(3,4-Dihydroxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against reticulocyte 15-lipoxygenase in rabbit was evaluated. | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286964 (CHEMBL177100 | N-{4-[4-(3,4-Dihydroxy-phenyl)-buty...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286956 (1-Hydroxy-naphthalene-2-carboxylic acid {4-[2-(3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286960 (CHEMBL175216 | N-{4-[2-(3,4-Dihydroxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM22372 (4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against rat basophilic leukemia cell 5-lipoxygenase | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286963 (4-Chloro-N-{4-[2-(3,4-dihydroxy-phenyl)-ethyl]-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286959 (2-Hydroxy-naphthalene-1-carboxylic acid {4-[2-(3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286958 (3-Chloro-N-{4-[2-(3,4-dihydroxy-phenyl)-ethyl]-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286967 (5-Bromo-N-{4-[2-(3,4-dihydroxy-phenyl)-ethyl]-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM22372 (4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286965 (CHEMBL177098 | N-{4-[2-(3,4-Dihydroxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286957 (CHEMBL177171 | N-{4-[2-(3,4-Dihydroxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human)) | BDBM22372 (4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against human platelet 12-lipoxygenase | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286961 (2-Hydroxy-N-{4-[2-(4-hydroxy-3-methoxy-phenyl)-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286968 (CHEMBL176634 | N-{4-[2-(3,4-Dihydroxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286966 (CHEMBL175315 | N-{4-[2-(3,4-Dimethoxy-phenyl)-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286955 (3-Hydroxy-biphenyl-4-carboxylic acid {4-[2-(3,4-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50286962 (3'-{4-[2-(3,4-Dihydroxy-phenyl)-ethyl]-phenylcarba...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit reticulocyte 15-lipoxygenase was evaluated by measuring inhibition of the conversion of linoleic acid to hydropero... | Bioorg Med Chem Lett 6: 93-96 (1996) Article DOI: 10.1016/0960-894X(95)00565-B BindingDB Entry DOI: 10.7270/Q2VM4C7S | |||||||||||
More data for this Ligand-Target Pair |