| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyunsaturated fatty acid lipoxygenase ALOX15 |
|---|
| Ligand | BDBM50286961 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_196592 |
|---|
| IC50 | >25000±n/a nM |
|---|
| Citation |  Tait, BD; Dyer, RD; Auerbach, BJ; Bornemeier, D; Guilds-Zamarka, L; Oxender, M; Roth, BD; Trivedi, BK; Cornicelli, JA Catechol based inhibitors of 15-lipoxygenase Bioorg Med Chem Lett6:93-96 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Polyunsaturated fatty acid lipoxygenase ALOX15 |
|---|
| Name: | Polyunsaturated fatty acid lipoxygenase ALOX15 |
|---|
| Synonyms: | 15-Lipoxygenase-1 (15-LOX-1) | ALOX15 | Arachidonate 15-lipoxygenase | Arachidonate 15-lipoxygenase-1 | LOG15 | LOX15_HUMAN | Reticulocyte 15-lipoxygenase-1 | Sphingosine 1-phosphate receptor 1 (S1P1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 74804.05 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 662 |
|---|
| Sequence: | MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL
LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP
QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK
GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV
LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL
VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH
LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST
GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS
LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH
ASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQ
PVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSV
AI
|
|
|
|---|
| BDBM50286961 |
|---|
| n/a |
|---|
| Name | BDBM50286961 |
|---|
| Synonyms: | 2-Hydroxy-N-{4-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-phenyl}-4-methyl-benzamide | CHEMBL172429 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H23NO4 |
|---|
| Mol. Mass. | 377.433 |
|---|
| SMILES | COc1cc(CCc2ccc(NC(=O)c3ccc(C)cc3O)cc2)ccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
