Compile Data Set for Download or QSAR

Found 27 hits with Last Name = 'cunningham' and Initial = 'am'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5328 (2-quinolinone deriv. 3 | 3-(1H-indol-2-yl)-1,2-dih...) Show SMILES O=c1[nH]c2ccccc2cc1-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C17H12N2O/c20-17-13(9-11-5-1-4-8-15(11)19-17)16-10-12-6-2-3-7-14(12)18-16/h1-10,18H,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5375 (1-phenyl-5-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1H...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C26H27N3O/c1-3-7-23(8-4-1)29-20-27-25-19-22(11-14-26(25)29)21-9-12-24(13-10-21)30-18-17-28-15-5-2-6-16-28/h1,3-4,7-14,19-20H,2,5-6,15-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5323 (1-[3-(4-methylpiperazin-1-yl)propyl]-3-[5-(thiophe...) Show SMILES CN1CCN(CCCn2cc(-c3cncc(c3)-c3ccsc3)c3ccccc23)CC1 Show InChI InChI=1S/C25H28N4S/c1-27-10-12-28(13-11-27)8-4-9-29-18-24(23-5-2-3-6-25(23)29)22-15-21(16-26-17-22)20-7-14-30-19-20/h2-3,5-7,14-19H,4,8-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5366 (1-phenyl-5-{6-[2-(piperidin-1-yl)ethoxy]pyridin-3-...) Show SMILES C(CN1CCCCC1)Oc1ccc(cn1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1-3-7-22(8-4-1)29-19-27-23-17-20(9-11-24(23)29)21-10-12-25(26-18-21)30-16-15-28-13-5-2-6-14-28/h1,3-4,7-12,17-19H,2,5-6,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5368 (4-(1-phenyl-1H-1,3-benzodiazol-5-yl)-1-[3-(piperid...) Show SMILES O=c1cc(ccn1CCCN1CCCCC1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C26H28N4O/c31-26-19-22(12-17-29(26)16-7-15-28-13-5-2-6-14-28)21-10-11-25-24(18-21)27-20-30(25)23-8-3-1-4-9-23/h1,3-4,8-12,17-20H,2,5-7,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5369 (5-(1-phenyl-1H-1,3-benzodiazol-5-yl)-1-[3-(piperid...) Show SMILES O=c1ccc(cn1CCCN1CCCCC1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C26H28N4O/c31-26-13-11-22(19-29(26)17-7-16-28-14-5-2-6-15-28)21-10-12-25-24(18-21)27-20-30(25)23-8-3-1-4-9-23/h1,3-4,8-13,18-20H,2,5-7,14-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5376 (1-[2-(4-{3-phenyl-3H-imidazo[4,5-b]pyridin-6-yl}ph...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1-3-7-22(8-4-1)29-19-27-24-17-21(18-26-25(24)29)20-9-11-23(12-10-20)30-16-15-28-13-5-2-6-14-28/h1,3-4,7-12,17-19H,2,5-6,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5322 (1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...) Show SMILES C(CN1CCCCC1)Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12 Show InChI InChI=1S/C25H27N3S/c1-4-10-27(11-5-1)12-6-13-28-18-24(23-7-2-3-8-25(23)28)22-15-21(16-26-17-22)20-9-14-29-19-20/h2-3,7-9,14-19H,1,4-6,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5327 (2-quinolinone deriv. 2 | 3-(1H-1,3-benzodiazol-2-y...) Show SMILES O=c1[nH]c2ccccc2cc1-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C16H11N3O/c20-16-11(9-10-5-1-2-6-12(10)19-16)15-17-13-7-3-4-8-14(13)18-15/h1-9H,(H,17,18)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5325 (3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3h | dimethy...) Show SMILES CC(CN(C)C)Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12 Show InChI InChI=1S/C23H25N3S/c1-17(13-25(2)3)14-26-15-22(21-6-4-5-7-23(21)26)20-10-19(11-24-12-20)18-8-9-27-16-18/h4-12,15-17H,13-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5367 (N-[2-(morpholin-4-yl)ethyl]-5-(1-phenyl-1H-1,3-ben...) Show SMILES C(CN1CCOCC1)Nc1ccc(cn1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C24H25N5O/c1-2-4-21(5-3-1)29-18-27-22-16-19(6-8-23(22)29)20-7-9-24(26-17-20)25-10-11-28-12-14-30-15-13-28/h1-9,16-18H,10-15H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5321 (3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3d | 4-(2-{3...) Show SMILES C(Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12)N1CCOCC1 Show InChI InChI=1S/C23H23N3OS/c1-2-4-23-21(3-1)22(16-26(23)7-6-25-8-10-27-11-9-25)20-13-19(14-24-15-20)18-5-12-28-17-18/h1-5,12-17H,6-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5324 (3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3g | dimethy...) Show SMILES CN(C)CCCn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12 Show InChI InChI=1S/C22H23N3S/c1-24(2)9-5-10-25-15-21(20-6-3-4-7-22(20)25)19-12-18(13-23-14-19)17-8-11-26-16-17/h3-4,6-8,11-16H,5,9-10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5370 (4-(1-phenyl-1H-1,3-benzodiazol-5-yl)-1-[2-(piperid...) Show SMILES O=c1cc(ccn1CCN1CCCCC1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c30-25-18-21(11-14-28(25)16-15-27-12-5-2-6-13-27)20-9-10-24-23(17-20)26-19-29(24)22-7-3-1-4-8-22/h1,3-4,7-11,14,17-19H,2,5-6,12-13,15-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5372 (4-(1-phenyl-1H-1,3-benzodiazol-5-yl)-1-[3-(piperid...) Show SMILES O=c1nc(ccn1CCCN1CCCCC1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C25H27N5O/c31-25-27-22(12-17-29(25)16-7-15-28-13-5-2-6-14-28)20-10-11-24-23(18-20)26-19-30(24)21-8-3-1-4-9-21/h1,3-4,8-12,17-19H,2,5-7,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5320 (1-[2-(piperidin-1-yl)ethyl]-3-[5-(thiophen-3-yl)py...) Show SMILES C(Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12)N1CCCCC1 Show InChI InChI=1S/C24H25N3S/c1-4-9-26(10-5-1)11-12-27-17-23(22-6-2-3-7-24(22)27)21-14-20(15-25-16-21)19-8-13-28-18-19/h2-3,6-8,13-18H,1,4-5,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5374 (4-(1H-1,3-benzodiazol-1-yl)-N-(3-chlorophenyl)pyri...) Show SMILES Clc1cccc(Nc2nccc(n2)-n2cnc3ccccc23)c1 Show InChI InChI=1S/C17H12ClN5/c18-12-4-3-5-13(10-12)21-17-19-9-8-16(22-17)23-11-20-14-6-1-2-7-15(14)23/h1-11H,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5319 (3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3b | dimethy...) Show SMILES CN(C)CCn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12 Show InChI InChI=1S/C21H21N3S/c1-23(2)8-9-24-14-20(19-5-3-4-6-21(19)24)18-11-17(12-22-13-18)16-7-10-25-15-16/h3-7,10-15H,8-9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5318 (3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3a | 3-[5-(t...) Show SMILES c1cc(cs1)-c1cncc(c1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C17H12N2S/c1-2-4-17-15(3-1)16(10-19-17)14-7-13(8-18-9-14)12-5-6-20-11-12/h1-11,19H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5312 (2,4-diaryloxazole deriv. 2a | N-{4-phenyl-2-[5-(th...) Show SMILES CC(=O)Nc1oc(nc1-c1ccccc1)-c1cncc(c1)-c1ccsc1 Show InChI InChI=1S/C20H15N3O2S/c1-13(24)22-20-18(14-5-3-2-4-6-14)23-19(25-20)17-9-16(10-21-11-17)15-7-8-26-12-15/h2-12H,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5371 (5-(1-phenyl-1H-1,3-benzodiazol-5-yl)-1-[2-(piperid...) Show SMILES O=c1ccc(cn1CCN1CCCCC1)-c1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c30-25-12-10-21(18-28(25)16-15-27-13-5-2-6-14-27)20-9-11-24-23(17-20)26-19-29(24)22-7-3-1-4-8-22/h1,3-4,7-12,17-19H,2,5-6,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2485-8 (2003) Article DOI: 10.1016/s0960-894x(03)00485-2 BindingDB Entry DOI: 10.7270/Q21R6NQ2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5326 (6-(1H-1,3-benzodiazol-2-yl)-7H-benzo[7]annulen-7-o...) Show SMILES O=c1ccc2ccccc2cc1-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C18H12N2O/c21-17-10-9-12-5-1-2-6-13(12)11-14(17)18-19-15-7-3-4-8-16(15)20-18/h1-11H,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5313 (2,4-diaryloxazole deriv. 2b | N-[4-phenyl-2-(5-phe...) Show SMILES CC(=O)Nc1oc(nc1-c1ccccc1)-c1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C22H17N3O2/c1-15(26)24-22-20(17-10-6-3-7-11-17)25-21(27-22)19-12-18(13-23-14-19)16-8-4-2-5-9-16/h2-14H,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5317 (2,4-diaryloxazole deriv. 2f | N-{2-[5-(4-methoxyph...) Show SMILES COc1ccc(cc1)-c1cncc(c1)-c1nc(c(NC(C)=O)o1)-c1ccccc1 Show InChI InChI=1S/C23H19N3O3/c1-15(27)25-23-21(17-6-4-3-5-7-17)26-22(29-23)19-12-18(13-24-14-19)16-8-10-20(28-2)11-9-16/h3-14H,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5316 (2,4-diaryloxazole deriv. 2e | N-{2-[5-(3-methoxyph...) Show SMILES COc1cccc(c1)-c1cncc(c1)-c1nc(c(NC(C)=O)o1)-c1ccccc1 Show InChI InChI=1S/C23H19N3O3/c1-15(27)25-23-21(16-7-4-3-5-8-16)26-22(29-23)19-11-18(13-24-14-19)17-9-6-10-20(12-17)28-2/h3-14H,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5314 (2,4-diaryloxazole deriv. 2c | N-{2-[5-(3-fluorophe...) Show SMILES CC(=O)Nc1oc(nc1-c1ccccc1)-c1cncc(c1)-c1cccc(F)c1 Show InChI InChI=1S/C22H16FN3O2/c1-14(27)25-22-20(15-6-3-2-4-7-15)26-21(28-22)18-10-17(12-24-13-18)16-8-5-9-19(23)11-16/h2-13H,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5315 (2,4-diaryloxazole deriv. 2d | N-{2-[5-(3-chlorophe...) Show SMILES CC(=O)Nc1oc(nc1-c1ccccc1)-c1cncc(c1)-c1cccc(Cl)c1 Show InChI InChI=1S/C22H16ClN3O2/c1-14(27)25-22-20(15-6-3-2-4-7-15)26-21(28-22)18-10-17(12-24-13-18)16-8-5-9-19(23)11-16/h2-13H,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.32E+3	n/a	n/a	n/a	n/a	7.4	22
Merck Research Laboratories					Assay Description Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...				Bioorg Med Chem Lett 13: 2973-6 (2003) Article DOI: 10.1016/s0960-894x(03)00627-9 BindingDB Entry DOI: 10.7270/Q2DZ06H6
					More data for this Ligand-Target Pair